JP2012508027A5 - - Google Patents

Download PDF

Info

Publication number
JP2012508027A5
JP2012508027A5 JP2011535765A JP2011535765A JP2012508027A5 JP 2012508027 A5 JP2012508027 A5 JP 2012508027A5 JP 2011535765 A JP2011535765 A JP 2011535765A JP 2011535765 A JP2011535765 A JP 2011535765A JP 2012508027 A5 JP2012508027 A5 JP 2012508027A5
Authority
JP
Japan
Prior art keywords
cadherin
seq
diabody
cells
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011535765A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012508027A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/063881 external-priority patent/WO2010054377A2/en
Publication of JP2012508027A publication Critical patent/JP2012508027A/ja
Publication of JP2012508027A5 publication Critical patent/JP2012508027A5/ja
Pending legal-status Critical Current

Links

JP2011535765A 2008-11-10 2009-11-10 N−カドヘリンに対する完全ヒト抗体 Pending JP2012508027A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11304208P 2008-11-10 2008-11-10
US61/113,042 2008-11-10
PCT/US2009/063881 WO2010054377A2 (en) 2008-11-10 2009-11-10 Fully human antibodies against n-cadherin

Publications (2)

Publication Number Publication Date
JP2012508027A JP2012508027A (ja) 2012-04-05
JP2012508027A5 true JP2012508027A5 (enExample) 2012-12-20

Family

ID=42153647

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011535765A Pending JP2012508027A (ja) 2008-11-10 2009-11-10 N−カドヘリンに対する完全ヒト抗体

Country Status (13)

Country Link
US (2) US8703920B2 (enExample)
EP (1) EP2356145A4 (enExample)
JP (1) JP2012508027A (enExample)
KR (1) KR20110084309A (enExample)
CN (1) CN102300873A (enExample)
AU (1) AU2009313239A1 (enExample)
BR (1) BRPI0921457A2 (enExample)
CA (1) CA2743122A1 (enExample)
CO (1) CO6362022A2 (enExample)
IL (1) IL212795A0 (enExample)
MX (1) MX2011004945A (enExample)
RU (1) RU2011123655A (enExample)
WO (1) WO2010054377A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8663635B2 (en) 2006-03-21 2014-03-04 The Regents Of The University Of California N-cadherin: target for cancer diagnosis and therapy
WO2007109347A2 (en) * 2006-03-21 2007-09-27 The Regents Of The University Of California N-cadherin and ly6 e: targets for cancer diagnosis and therapy
KR20100132998A (ko) * 2008-04-04 2010-12-20 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 종양 성장, 혈관신생 및 전이를 차단하는 것을 목표로 하는 암에 대한 항체
US8703920B2 (en) 2008-11-10 2014-04-22 The Regents Of The University Of California Fully human antibodies against N-cadherin
GB201119089D0 (en) 2011-11-04 2011-12-21 Isis Innovation Treatment of musculoskeletal fibroproliferative disorders
EP2830659A1 (en) 2012-03-27 2015-02-04 Novartis AG Treatment of fibrosis
CN107076160B (zh) * 2014-08-21 2019-12-20 江森自控科技公司 电池监测系统
US20200165351A1 (en) * 2017-06-06 2020-05-28 The Regents Of The University Of California Humanized anti-n-cadherin antibodies and uses thereof
EP4337702A1 (en) * 2021-05-13 2024-03-20 Wuxi Biologics Ireland Limited Antibody conjugate comprising anti-p-cadherin antibody and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889157A (en) 1990-10-12 1999-03-30 The United States Of America As Represented By The Department Of Health And Human Services Humanized B3 antibody fragments, fusion proteins, and uses thereof
AU669124B2 (en) 1991-09-18 1996-05-30 Kyowa Hakko Kirin Co., Ltd. Process for producing humanized chimera antibody
US6680175B2 (en) 1998-05-05 2004-01-20 Adherex Technologies, Inc. Methods for diagnosing and evaluating cancer
US6277824B1 (en) 1998-07-10 2001-08-21 Adherex Technologies Compounds and methods for modulating adhesion molecule function
WO2001062206A2 (en) 2000-02-22 2001-08-30 Mount Sinai School Of Medicine Of New York University N-cadherin modulated migration, invasion, and metastasis
US20030190602A1 (en) 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
DK1629011T3 (da) * 2003-05-31 2010-05-03 Micromet Ag Humane anti-humane-DC3-bindingsmolekyler
US7973139B2 (en) * 2004-03-26 2011-07-05 Human Genome Sciences, Inc. Antibodies against nogo receptor
AU2006259583A1 (en) 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20100278821A1 (en) 2006-03-21 2010-11-04 The Regents Of The University Of California N-cadherin: target for cancer diagnosis and therapy
US8663635B2 (en) 2006-03-21 2014-03-04 The Regents Of The University Of California N-cadherin: target for cancer diagnosis and therapy
WO2007109347A2 (en) 2006-03-21 2007-09-27 The Regents Of The University Of California N-cadherin and ly6 e: targets for cancer diagnosis and therapy
KR20100132998A (ko) 2008-04-04 2010-12-20 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 종양 성장, 혈관신생 및 전이를 차단하는 것을 목표로 하는 암에 대한 항체
US8703920B2 (en) 2008-11-10 2014-04-22 The Regents Of The University Of California Fully human antibodies against N-cadherin

Similar Documents

Publication Publication Date Title
JP2012508027A5 (enExample)
CN110536900B (zh) 调节补体依赖性细胞溶解效应子功能的修饰的人igm恒定区
CN105837688B (zh) 单域抗体及其编码基因,免疫毒素及其编码基因、制备方法、表达载体、应用,及宿主细胞
CN106117354B (zh) 一种全人源抗CD47的全分子IgG抗体及其应用
RU2009118621A (ru) Агонистические антитела против notch3 и их применение для лечения ntch3-ассоциированных заболеваний
JP2003510366A (ja) Aprilレセプター(bcma)およびその使用
KR101671955B1 (ko) 항 TNF-α/CXCL10 이중 타겟 항체 및 그의 용도
CN113480657B (zh) 针对her2的单域抗体及其衍生蛋白和应用
CN109206514A (zh) Tslp单克隆抗体及其制备方法和应用
TWI688575B (zh) 阻礙血管內皮脂酶之酵素活性的人類化單株抗體
CN109705225B (zh) 一种抗人caix抗原的嵌合抗原受体及其应用
WO2003106499A1 (ja) 抗体および阻害剤並びにそれを用いた形質転換方法および形質転換キット
CN113321721B (zh) 一种细胞外Ezrin蛋白及其应用
CN115058430B (zh) 一种拟穴青蟹5-ht2受体基因及其应用
CA2323091A1 (en) Nephrin gene and protein
CN117866903B (zh) 单域抗体修饰的干细胞及其在疾病治疗中用途
CN101544695B (zh) 人源化抗cd25单链抗体及制备方法
JP6574033B2 (ja) Wnt蛋白質の製造方法および保存方法
KR20100118900A (ko) 사이토케라틴17―특이적인 인간항체
CN117866902A (zh) 具有抗il-17a活性的基因修饰干细胞及其制备方法以及药物组合物
CN110117325B (zh) 一种猪cd127多肽及其编码基因和应用
JP3288716B2 (ja) ヒト接着分子オクルディン
CN107686519A (zh) 抗小鼠mxra7单克隆抗体的制备方法及其应用
CN120040594B (zh) 一种靶向flt3基因编辑通用型car-t细胞的制备方法和应用
CN120005027B (zh) 大口黑鲈cd6抗原结合肽、及其单克隆抗体和应用