JP2012507026A5 - - Google Patents
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- Publication number
- JP2012507026A5 JP2012507026A5 JP2011533750A JP2011533750A JP2012507026A5 JP 2012507026 A5 JP2012507026 A5 JP 2012507026A5 JP 2011533750 A JP2011533750 A JP 2011533750A JP 2011533750 A JP2011533750 A JP 2011533750A JP 2012507026 A5 JP2012507026 A5 JP 2012507026A5
- Authority
- JP
- Japan
- Prior art keywords
- vegfb
- thbs1
- pgf
- patient
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108010073925 Vascular Endothelial Growth Factor B Proteins 0.000 claims 32
- 102100038217 Vascular endothelial growth factor B Human genes 0.000 claims 32
- 101000595923 Homo sapiens Placenta growth factor Proteins 0.000 claims 28
- 102100035194 Placenta growth factor Human genes 0.000 claims 28
- 102000007614 Thrombospondin 1 Human genes 0.000 claims 28
- 108010046722 Thrombospondin 1 Proteins 0.000 claims 28
- 238000000034 method Methods 0.000 claims 24
- 239000000523 sample Substances 0.000 claims 20
- 208000010125 myocardial infarction Diseases 0.000 claims 11
- 208000019622 heart disease Diseases 0.000 claims 10
- 210000001124 body fluid Anatomy 0.000 claims 8
- 239000010839 body fluid Substances 0.000 claims 6
- 238000004393 prognosis Methods 0.000 claims 6
- 206010061216 Infarction Diseases 0.000 claims 5
- 239000003153 chemical reaction reagent Substances 0.000 claims 5
- 230000007574 infarction Effects 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 4
- 108020004999 messenger RNA Proteins 0.000 claims 3
- 239000013610 patient sample Substances 0.000 claims 3
- 102000004506 Blood Proteins Human genes 0.000 claims 2
- 108010017384 Blood Proteins Proteins 0.000 claims 2
- 206010019280 Heart failures Diseases 0.000 claims 2
- 108010090804 Streptavidin Proteins 0.000 claims 2
- 238000004458 analytical method Methods 0.000 claims 2
- 239000013074 reference sample Substances 0.000 claims 2
- 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 1
- 208000031229 Cardiomyopathies Diseases 0.000 claims 1
- 238000008157 ELISA kit Methods 0.000 claims 1
- 206010048858 Ischaemic cardiomyopathy Diseases 0.000 claims 1
- 208000033774 Ventricular Remodeling Diseases 0.000 claims 1
- 239000013060 biological fluid Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 238000007619 statistical method Methods 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10964908P | 2008-10-30 | 2008-10-30 | |
| US61/109,649 | 2008-10-30 | ||
| PCT/EP2009/064410 WO2010049538A1 (en) | 2008-10-30 | 2009-10-30 | Biomarkers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012507026A JP2012507026A (ja) | 2012-03-22 |
| JP2012507026A5 true JP2012507026A5 (cg-RX-API-DMAC7.html) | 2012-12-13 |
| JP5749171B2 JP5749171B2 (ja) | 2015-07-15 |
Family
ID=41528764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011533750A Expired - Fee Related JP5749171B2 (ja) | 2008-10-30 | 2009-10-30 | バイオマーカー |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20110294683A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2362942B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5749171B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102203606A (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0920069A8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2741117A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2640900T3 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2545757C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010049538A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG186953A1 (en) | 2010-07-09 | 2013-02-28 | Somalogic Inc | Lung cancer biomarkers and uses thereof |
| US20120040861A1 (en) | 2010-08-13 | 2012-02-16 | Somalogic, Inc. | Pancreatic Cancer Biomarkers and Uses Thereof |
| EP2592422A1 (en) * | 2011-11-08 | 2013-05-15 | Zora Biosciences OY | Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients undergoing statin treatment |
| EP2592423A1 (en) | 2011-11-08 | 2013-05-15 | Zora Biosciences OY | Lipidomic biomarkers for the prediction of cardiovascular outcomes in coronary artery disease patients not undergoing statin treatment |
| JP2014207883A (ja) * | 2013-03-27 | 2014-11-06 | 国立大学法人岡山大学 | がん幹細胞及びその用途 |
| CN105451758A (zh) * | 2013-05-31 | 2016-03-30 | 科比欧尔斯公司 | 用于心力衰竭的预防或治疗的人plgf-2 |
| EP3441768A3 (en) | 2013-08-26 | 2019-03-20 | Roche Diagnostics GmbH | Marker for statin treatment stratification in heart failure |
| CN103487586B (zh) * | 2013-09-04 | 2015-07-15 | 石家庄洹众生物科技有限公司 | 一种定量检测可溶性生长刺激表达蛋白2的试验装置 |
| PL228091B1 (pl) * | 2014-02-12 | 2018-02-28 | Inst Biochemii I Biofizyki Polskiej Akademii Nauk | Zestaw biomarkerów transkryptomicznych do zastosowania w stratyfikacji indywidualnego ryzyka rozwoju pozawałowej niewydolnosci serca, sposób diagnozowania ryzyka wystapienia u pacjenta pozawałowej niewydolnosci serca i zastosowanie biomarkerów do diagnostyki in vitro |
| US10041120B2 (en) | 2014-05-28 | 2018-08-07 | Scripps Health | Predictive analysis for myocardial infarction |
| CN105243294B (zh) * | 2015-09-18 | 2017-06-09 | 淮南师范学院 | 一种用于预测癌症病人预后相关的蛋白质对的方法 |
| RU2634375C2 (ru) * | 2016-04-18 | 2017-10-26 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт кардиологии" | Способ предупреждения постинфарктного ремоделирования сердца в эксперименте |
| EP4322168A3 (en) * | 2016-07-06 | 2024-05-15 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
| DE102017116204B4 (de) | 2017-07-18 | 2024-06-27 | Universität Rostock | Verfahren zur Vorhersage der Antwort auf die kardiovaskuläre Regeneration |
| US11708600B2 (en) * | 2017-10-05 | 2023-07-25 | Decode Health, Inc. | Long non-coding RNA gene expression signatures in disease diagnosis |
| EP4038629A1 (en) * | 2019-09-30 | 2022-08-10 | F. Hoffmann-La Roche AG | Prediction of disease status |
| JP7489059B2 (ja) * | 2020-04-21 | 2024-05-23 | 国立大学法人横浜国立大学 | 画像生成装置、表示装置、画像生成方法、提示方法およびプログラム |
| US11915807B1 (en) * | 2022-10-11 | 2024-02-27 | Flatiron Health, Inc. | Machine learning extraction of clinical variable values for subjects from clinical record data |
| US11854675B1 (en) | 2022-10-11 | 2023-12-26 | Flatiron Health, Inc. | Machine learning extraction of clinical variable values for subjects from clinical record data |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004513328A (ja) * | 1999-03-03 | 2004-04-30 | ルードヴィッヒ インスティテュート フォー キャンサー リサーチ | 血管内皮増殖因子（ｖｅｇｆ−ｂ）欠損動物の心臓異常及びこれら心臓異常に関する方法 |
| CN1260492A (zh) * | 1999-11-09 | 2000-07-19 | 赵永同 | 肿瘤预后评估试剂盒及其制备工艺 |
| CN1139811C (zh) * | 1999-11-09 | 2004-02-25 | 赵永同 | 肿瘤早期检测评估试剂盒及其制备工艺 |
| EP1230552B1 (en) * | 1999-11-16 | 2006-01-11 | Genentech, Inc. | Elisa for vegf |
| CN1441849A (zh) * | 2000-05-17 | 2003-09-10 | 路德维格癌症研究所 | 检测肿瘤细胞的存在及筛选抗肿瘤剂的方法 |
| CA2451311A1 (en) * | 2001-06-20 | 2003-01-03 | Ludwig Institute For Cancer Research | Stimulation of vascularization with vegf-b |
| US20030143572A1 (en) * | 2001-08-13 | 2003-07-31 | Lu Mou-Ying Fu | Molecular diagnostic and computerized decision support system for selecting the optimum treatment for human cancer |
| US20030096248A1 (en) * | 2001-09-04 | 2003-05-22 | Vitivity, Inc. | Diagnosis and treatment of vascular disease |
| US7435419B2 (en) * | 2002-07-19 | 2008-10-14 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating pre-eclampsia or eclampsia |
| JP4741249B2 (ja) * | 2002-11-16 | 2011-08-03 | シーメンス・ヘルスケア・ダイアグノスティックス・プロダクツ・ゲーエムベーハー | 心血管疾患における生化学的マーカーの組合せとしてのｓＣＤ４０Ｌ，ＰＡＰＰ−Ａおよび胎盤増殖因子（ＰｌＧＦ） |
| WO2005054860A1 (en) * | 2003-12-01 | 2005-06-16 | Dako Denmark A/S | Methods and compositions for immuno-histochemical detection |
| CN101426489A (zh) * | 2004-04-16 | 2009-05-06 | 曹义海 | 抑制血管生成的成分和方法 |
| US20070037232A1 (en) * | 2005-03-31 | 2007-02-15 | Barasch Jonathan M | Detection of NGAL in chronic renal disease |
| TW200732347A (en) * | 2005-10-06 | 2007-09-01 | Trophogen Inc | VEGF analogs and methods of use |
-
2009
- 2009-10-30 ES ES09752320.3T patent/ES2640900T3/es active Active
- 2009-10-30 RU RU2011121613/15A patent/RU2545757C2/ru active
- 2009-10-30 CN CN200980143296XA patent/CN102203606A/zh active Pending
- 2009-10-30 BR BRPI0920069A patent/BRPI0920069A8/pt not_active IP Right Cessation
- 2009-10-30 JP JP2011533750A patent/JP5749171B2/ja not_active Expired - Fee Related
- 2009-10-30 EP EP09752320.3A patent/EP2362942B1/en not_active Not-in-force
- 2009-10-30 CA CA2741117A patent/CA2741117A1/en not_active Abandoned
- 2009-10-30 US US12/998,543 patent/US20110294683A1/en not_active Abandoned
- 2009-10-30 WO PCT/EP2009/064410 patent/WO2010049538A1/en not_active Ceased
-
2015
- 2015-09-22 US US14/861,506 patent/US20160188835A1/en not_active Abandoned
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