JP2012506861A5 - - Google Patents
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- Publication number
- JP2012506861A5 JP2012506861A5 JP2011533328A JP2011533328A JP2012506861A5 JP 2012506861 A5 JP2012506861 A5 JP 2012506861A5 JP 2011533328 A JP2011533328 A JP 2011533328A JP 2011533328 A JP2011533328 A JP 2011533328A JP 2012506861 A5 JP2012506861 A5 JP 2012506861A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- therapeutic agent
- pellet
- prepared
- debranched starch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 9
- 239000008188 pellet Substances 0.000 claims 5
- 229920002472 Starch Polymers 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 235000019698 starch Nutrition 0.000 claims 4
- 239000008107 starch Substances 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- 229920001685 Amylomaize Polymers 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 108090000637 alpha-Amylases Proteins 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 238000005563 spheronization Methods 0.000 claims 1
- 229940120293 vaginal suppository Drugs 0.000 claims 1
- 239000006216 vaginal suppository Substances 0.000 claims 1
- 229940044977 vaginal tablet Drugs 0.000 claims 1
- 239000000003 vaginal tablet Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10778408P | 2008-10-23 | 2008-10-23 | |
| US61/107,784 | 2008-10-23 | ||
| PCT/US2009/061662 WO2010048389A2 (en) | 2008-10-23 | 2009-10-22 | Pharmaceutical pellets comprising modified starch and therapeutic applications therefor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012506861A JP2012506861A (ja) | 2012-03-22 |
| JP2012506861A5 true JP2012506861A5 (enExample) | 2012-12-06 |
| JP5608167B2 JP5608167B2 (ja) | 2014-10-15 |
Family
ID=42118112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011533328A Expired - Fee Related JP5608167B2 (ja) | 2008-10-23 | 2009-10-22 | 加工デンプンを含む医薬ペレット、およびそれの治療への応用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20100105784A1 (enExample) |
| EP (1) | EP2344121B1 (enExample) |
| JP (1) | JP5608167B2 (enExample) |
| KR (1) | KR20110073618A (enExample) |
| CN (1) | CN102202648B (enExample) |
| BR (1) | BRPI0919869A2 (enExample) |
| RU (1) | RU2519715C2 (enExample) |
| TW (1) | TWI500429B (enExample) |
| WO (1) | WO2010048389A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2554347C2 (ru) | 2008-08-19 | 2015-06-27 | Ксенопорт, Инк. | Пролекарства метилгидрофумарата, фармацевтические композиции с ними и способы применения |
| MX2013012745A (es) * | 2011-05-02 | 2014-12-05 | Aptalis Pharmatech Inc | Composiciones en forma de comprmido de disolución rápida para administración vaginal. |
| EP2887934A1 (en) | 2012-08-22 | 2015-07-01 | XenoPort, Inc. | Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects |
| AU2013305684B2 (en) | 2012-08-22 | 2016-11-24 | Xenoport, Inc. | Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof |
| WO2014160633A1 (en) | 2013-03-24 | 2014-10-02 | Xenoport, Inc. | Pharmaceutical compositions of dimethyl fumarate |
| US9302977B2 (en) | 2013-06-07 | 2016-04-05 | Xenoport, Inc. | Method of making monomethyl fumarate |
| WO2014205392A1 (en) | 2013-06-21 | 2014-12-24 | Xenoport, Inc. | Cocrystals of dimethyl fumarate |
| WO2015035184A1 (en) | 2013-09-06 | 2015-03-12 | Xenoport, Inc. | Crystalline forms of (n,n-diethylcarbamoyl)methyl methyl (2e)but-2-ene-1,4-dioate, methods of synthesis and use |
| US9999672B2 (en) | 2014-03-24 | 2018-06-19 | Xenoport, Inc. | Pharmaceutical compositions of fumaric acid esters |
| EP3787656A1 (en) * | 2018-05-04 | 2021-03-10 | The Procter & Gamble Company | Compositions and methods for treating vaginal dryness |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8723846D0 (en) * | 1987-10-10 | 1987-11-11 | Danbiosyst Ltd | Bioadhesive microsphere drug delivery system |
| CH678697A5 (enExample) * | 1989-04-03 | 1991-10-31 | Warner Lambert Co | |
| US5468286A (en) * | 1989-10-25 | 1995-11-21 | National Starch And Chemical Investment Holding Corporation | Enzymatically debranched starches as tablet excipients |
| US5281276A (en) * | 1992-03-25 | 1994-01-25 | National Starch And Chemical Investment Holding Corporation | Process for making amylase resistant starch from high amylose starch |
| US5260068A (en) * | 1992-05-04 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Multiparticulate pulsatile drug delivery system |
| NL9201195A (nl) * | 1992-07-03 | 1994-02-01 | Tno | Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat. |
| CA2211778A1 (en) * | 1997-08-14 | 1999-02-14 | Francois Carriere | Preparation of pregelatinized high amylose starch and debranched starch useful as an excipient for controlled release of active agents |
| DK1079810T3 (da) * | 1998-04-22 | 2004-11-01 | Glycologic Ltd | Oralt administrerbare sammensætninger, der omfatter kationtværbundet polysaccharid og en polymer, som er fordöjelig i den nedre mave-tarmkanal |
| US7262170B2 (en) * | 1998-04-26 | 2007-08-28 | Zhongming Zeng | Pharmaceutical composition for reducing vaginal acidity and treatment of vaginitis, and the use thereof |
| US7238677B2 (en) * | 2003-03-28 | 2007-07-03 | Kimberly-Clark Worldwide, Inc. | Prevention of urogenital infections |
| US7276486B2 (en) * | 2004-03-15 | 2007-10-02 | Kimberly-Clark Worldwide, Inc. | Compositions for vaginal treatment |
| US20050214364A1 (en) * | 2004-03-23 | 2005-09-29 | Hutman Herbert W | Products and methods for treating vaginal infections |
| BRPI0602614A (pt) * | 2005-05-02 | 2006-12-26 | Nat Starch Chem Invest | utilização de amido desramificado na extrusão - esferonização de pelotas farmacêuticas |
| US8318230B2 (en) * | 2005-05-02 | 2012-11-27 | Henkel Ag & Co. Kgaa | Use of debranched starch in extrusion-spheronization pharmaceutical pellets |
| EP1872775A1 (en) * | 2006-06-29 | 2008-01-02 | Polichem S.A. | Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders |
-
2009
- 2009-10-22 RU RU2011120438/15A patent/RU2519715C2/ru not_active IP Right Cessation
- 2009-10-22 JP JP2011533328A patent/JP5608167B2/ja not_active Expired - Fee Related
- 2009-10-22 EP EP09744012.7A patent/EP2344121B1/en active Active
- 2009-10-22 US US12/603,917 patent/US20100105784A1/en not_active Abandoned
- 2009-10-22 CN CN200980142499.7A patent/CN102202648B/zh not_active Expired - Fee Related
- 2009-10-22 KR KR1020117011716A patent/KR20110073618A/ko not_active Ceased
- 2009-10-22 WO PCT/US2009/061662 patent/WO2010048389A2/en not_active Ceased
- 2009-10-22 BR BRPI0919869A patent/BRPI0919869A2/pt not_active IP Right Cessation
- 2009-10-23 TW TW098136057A patent/TWI500429B/zh not_active IP Right Cessation
-
2012
- 2012-04-24 US US13/454,592 patent/US20120207823A1/en not_active Abandoned
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