JP2008531710A5 - - Google Patents
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- Publication number
- JP2008531710A5 JP2008531710A5 JP2007558177A JP2007558177A JP2008531710A5 JP 2008531710 A5 JP2008531710 A5 JP 2008531710A5 JP 2007558177 A JP2007558177 A JP 2007558177A JP 2007558177 A JP2007558177 A JP 2007558177A JP 2008531710 A5 JP2008531710 A5 JP 2008531710A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- cell
- sod protein
- pyrimethamine
- administering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 102000007399 Nuclear hormone receptor Human genes 0.000 claims 1
- 108020005497 Nuclear hormone receptor Proteins 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 108020004017 nuclear receptors Proteins 0.000 claims 1
- 239000002831 pharmacologic agent Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- WKSAUQYGYAYLPV-UHFFFAOYSA-N pyrimethamine Chemical compound CCC1=NC(N)=NC(N)=C1C1=CC=C(Cl)C=C1 WKSAUQYGYAYLPV-UHFFFAOYSA-N 0.000 claims 1
- 229960000611 pyrimethamine Drugs 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65850505P | 2005-03-04 | 2005-03-04 | |
| PCT/US2006/007257 WO2006096405A2 (en) | 2005-03-04 | 2006-03-01 | Treatment of amyotrophic lateral sclerosis with pyrimethamine and analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008531710A JP2008531710A (ja) | 2008-08-14 |
| JP2008531710A5 true JP2008531710A5 (enExample) | 2009-11-26 |
Family
ID=36953835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007558177A Pending JP2008531710A (ja) | 2005-03-04 | 2006-03-01 | 神経変性疾患の調節 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060211645A1 (enExample) |
| EP (1) | EP1917017B1 (enExample) |
| JP (1) | JP2008531710A (enExample) |
| CN (1) | CN101184493A (enExample) |
| AT (1) | ATE456953T1 (enExample) |
| AU (1) | AU2006220919A1 (enExample) |
| CA (1) | CA2600067A1 (enExample) |
| DE (1) | DE602006012115D1 (enExample) |
| ES (1) | ES2340708T3 (enExample) |
| WO (1) | WO2006096405A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006096415A2 (en) * | 2005-03-04 | 2006-09-14 | Alsgen, Llc | Modulation of neurodegenerative diseases through the estrogen receptor |
| JP2008536808A (ja) * | 2005-03-04 | 2008-09-11 | アルスジエン・インコーポレーテツド | プロゲステロン受容体による神経変性疾患の調節 |
| US20070135437A1 (en) * | 2005-03-04 | 2007-06-14 | Alsgen, Inc. | Modulation of neurodegenerative diseases |
| WO2008046056A1 (en) * | 2006-10-13 | 2008-04-17 | Welldoc Communications, Inc. | Reduction of nonspecific binding in nucleic acid assays and nucleic acid synthesis reactions |
| US20110092554A1 (en) * | 2007-11-19 | 2011-04-21 | Richard Chesworth | 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders |
| WO2009086277A1 (en) | 2007-12-20 | 2009-07-09 | Envivo Pharmaceuticals, Inc. | Tetrasubstituted benzenes |
| CA2762680C (en) | 2009-05-21 | 2018-04-17 | Chlorion Pharma, Inc. | Methyl sulfanyl pyrmidmes useful as antiinflammatories, analgesics, and antiepileptics |
| GB201015079D0 (en) * | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
| US9073947B2 (en) * | 2011-06-10 | 2015-07-07 | Merck Patent Gmbh | Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity |
| CN104398517A (zh) * | 2014-11-28 | 2015-03-11 | 四川大学 | 乙胺嘧啶的新用途及治疗肿瘤的药物组合物 |
| WO2021096199A1 (ko) * | 2019-11-11 | 2021-05-20 | 에스케이케미칼 주식회사 | 피리메타민을 유효성분으로 포함하는 면역 관련 질환의 치료 또는 예방용 약학 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5231170A (en) * | 1986-08-27 | 1993-07-27 | Paul Averback | Antibodies to dense microspheres |
| US5866562A (en) * | 1996-10-25 | 1999-02-02 | Bayer Aktiengesellschaft | Ring-bridged bis-quinolines |
| US7442629B2 (en) * | 2004-09-24 | 2008-10-28 | President & Fellows Of Harvard College | Femtosecond laser-induced formation of submicrometer spikes on a semiconductor substrate |
| IL162210A0 (en) * | 2001-11-28 | 2005-11-20 | Btg Int Ltd | Preventives or remedies for alzheimer's disease oramyloid protein fibrosis inhibitors containing ni trogen-containing heteroaryl |
| CA2479036A1 (en) * | 2002-03-13 | 2003-09-18 | Euro-Celtique S.A. | Aryl substituted pyrimidines and the use thereof |
| US20050026823A1 (en) * | 2003-06-20 | 2005-02-03 | Biomarin Pharmaceutical Inc. | Use of the chaperone receptor-associated protein (RAP) for the delivery of therapeutic compounds to the brain and other tissues |
| JP2008536808A (ja) * | 2005-03-04 | 2008-09-11 | アルスジエン・インコーポレーテツド | プロゲステロン受容体による神経変性疾患の調節 |
| US20070135437A1 (en) * | 2005-03-04 | 2007-06-14 | Alsgen, Inc. | Modulation of neurodegenerative diseases |
-
2006
- 2006-03-01 CN CNA2006800153119A patent/CN101184493A/zh active Pending
- 2006-03-01 CA CA002600067A patent/CA2600067A1/en not_active Abandoned
- 2006-03-01 DE DE602006012115T patent/DE602006012115D1/de not_active Expired - Lifetime
- 2006-03-01 EP EP06736552A patent/EP1917017B1/en not_active Expired - Lifetime
- 2006-03-01 US US11/365,462 patent/US20060211645A1/en not_active Abandoned
- 2006-03-01 ES ES06736552T patent/ES2340708T3/es not_active Expired - Lifetime
- 2006-03-01 AU AU2006220919A patent/AU2006220919A1/en not_active Abandoned
- 2006-03-01 AT AT06736552T patent/ATE456953T1/de not_active IP Right Cessation
- 2006-03-01 JP JP2007558177A patent/JP2008531710A/ja active Pending
- 2006-03-01 WO PCT/US2006/007257 patent/WO2006096405A2/en not_active Ceased
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