JP2008531710A - 神経変性疾患の調節 - Google Patents

神経変性疾患の調節 Download PDF

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Publication number
JP2008531710A
JP2008531710A JP2007558177A JP2007558177A JP2008531710A JP 2008531710 A JP2008531710 A JP 2008531710A JP 2007558177 A JP2007558177 A JP 2007558177A JP 2007558177 A JP2007558177 A JP 2007558177A JP 2008531710 A JP2008531710 A JP 2008531710A
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Japan
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group
sod
substituted
protein
pyrimethamine
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English (en)
Japanese (ja)
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JP2008531710A5 (enExample
Inventor
スコツト,シーン
ベンジヤミン,ダニエル
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アルスジエン・インコーポレーテツド
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Publication of JP2008531710A publication Critical patent/JP2008531710A/ja
Publication of JP2008531710A5 publication Critical patent/JP2008531710A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polyurethanes Or Polyureas (AREA)
JP2007558177A 2005-03-04 2006-03-01 神経変性疾患の調節 Pending JP2008531710A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65850505P 2005-03-04 2005-03-04
PCT/US2006/007257 WO2006096405A2 (en) 2005-03-04 2006-03-01 Treatment of amyotrophic lateral sclerosis with pyrimethamine and analogues

Publications (2)

Publication Number Publication Date
JP2008531710A true JP2008531710A (ja) 2008-08-14
JP2008531710A5 JP2008531710A5 (enExample) 2009-11-26

Family

ID=36953835

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007558177A Pending JP2008531710A (ja) 2005-03-04 2006-03-01 神経変性疾患の調節

Country Status (10)

Country Link
US (1) US20060211645A1 (enExample)
EP (1) EP1917017B1 (enExample)
JP (1) JP2008531710A (enExample)
CN (1) CN101184493A (enExample)
AT (1) ATE456953T1 (enExample)
AU (1) AU2006220919A1 (enExample)
CA (1) CA2600067A1 (enExample)
DE (1) DE602006012115D1 (enExample)
ES (1) ES2340708T3 (enExample)
WO (1) WO2006096405A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017066165A (ja) * 2010-09-10 2017-04-06 ヘルパービー セラピューティクス リミテッドHelperby Therapeutics Limited 微生物感染の治療薬

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006096404A2 (en) * 2005-03-04 2006-09-14 Alsgen, Inc Treatment of amyotrophic lateral sclerosis with norethindrone and anal0gues
US20060211673A1 (en) * 2005-03-04 2006-09-21 Alsgen, Llc Modulation of neurodegenerative diseases through the estrogen receptor
US20070135437A1 (en) * 2005-03-04 2007-06-14 Alsgen, Inc. Modulation of neurodegenerative diseases
US20080153094A1 (en) * 2006-10-13 2008-06-26 Minor James M Reduction of nonspecific binding in nucleic acid assays and nucleic acid synthesis reactions
US20110092554A1 (en) * 2007-11-19 2011-04-21 Richard Chesworth 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders
AU2008345573B2 (en) 2007-12-20 2013-12-19 Envivo Pharmaceuticals, Inc. Tetrasubstituted benzenes
US9040538B2 (en) * 2009-05-21 2015-05-26 Universite Laval Pyrimidines as novel therapeutic agents
KR20180084153A (ko) 2011-06-10 2018-07-24 메르크 파텐트 게엠베하 Btk 억제 활성을 갖는 피리미딘 및 피리딘 화합물의 조성물 및 제조방법
CN104398517A (zh) * 2014-11-28 2015-03-11 四川大学 乙胺嘧啶的新用途及治疗肿瘤的药物组合物
WO2021096199A1 (ko) * 2019-11-11 2021-05-20 에스케이케미칼 주식회사 피리메타민을 유효성분으로 포함하는 면역 관련 질환의 치료 또는 예방용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231170A (en) * 1986-08-27 1993-07-27 Paul Averback Antibodies to dense microspheres
US5866562A (en) * 1996-10-25 1999-02-02 Bayer Aktiengesellschaft Ring-bridged bis-quinolines
US7442629B2 (en) * 2004-09-24 2008-10-28 President & Fellows Of Harvard College Femtosecond laser-induced formation of submicrometer spikes on a semiconductor substrate
ES2330090T3 (es) * 2001-11-28 2009-12-04 Btg International Limited Agentes profilacticos o remedios para la enfermedad de alzheimer o unhibidores de la fibrosis de las proteinas amiloides que contiene compuestos de heteroarilo que contiene nitrogeno.
KR20040099324A (ko) * 2002-03-13 2004-11-26 유로-셀티큐 에스.에이. 아릴 치환된 피리미딘 및 이것의 용도
US20050026823A1 (en) * 2003-06-20 2005-02-03 Biomarin Pharmaceutical Inc. Use of the chaperone receptor-associated protein (RAP) for the delivery of therapeutic compounds to the brain and other tissues
WO2006096404A2 (en) * 2005-03-04 2006-09-14 Alsgen, Inc Treatment of amyotrophic lateral sclerosis with norethindrone and anal0gues
US20070135437A1 (en) * 2005-03-04 2007-06-14 Alsgen, Inc. Modulation of neurodegenerative diseases

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017066165A (ja) * 2010-09-10 2017-04-06 ヘルパービー セラピューティクス リミテッドHelperby Therapeutics Limited 微生物感染の治療薬
US10265373B2 (en) 2010-09-10 2019-04-23 Helperby Therapeutics Limited Pharmaceutical composition and method of treating a microbial infection with sulcotidil

Also Published As

Publication number Publication date
CN101184493A (zh) 2008-05-21
US20060211645A1 (en) 2006-09-21
CA2600067A1 (en) 2006-09-14
EP1917017A2 (en) 2008-05-07
AU2006220919A1 (en) 2006-09-14
EP1917017B1 (en) 2010-02-03
WO2006096405A2 (en) 2006-09-14
DE602006012115D1 (de) 2010-03-25
WO2006096405A3 (en) 2007-05-18
ES2340708T3 (es) 2010-06-08
ATE456953T1 (de) 2010-02-15
WO2006096405A8 (en) 2008-04-10

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