JP2012506551A - 骨または軟骨障害の検出および診断のための方法 - Google Patents

骨または軟骨障害の検出および診断のための方法 Download PDF

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JP2012506551A
JP2012506551A JP2011532635A JP2011532635A JP2012506551A JP 2012506551 A JP2012506551 A JP 2012506551A JP 2011532635 A JP2011532635 A JP 2011532635A JP 2011532635 A JP2011532635 A JP 2011532635A JP 2012506551 A JP2012506551 A JP 2012506551A
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antibody
polypeptide
bone
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JP2012506551A5 (enExample
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ボロスズクズク，ボルフガンク
ハバ，ゲルハルト
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バイオマーカー デザイン フォルシュングス ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Urology & Nephrology (AREA)
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  • General Physics & Mathematics (AREA)
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  • Peptides Or Proteins (AREA)
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JP2011532635A 2008-10-22 2009-10-22 骨または軟骨障害の検出および診断のための方法 Pending JP2012506551A (ja)

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Application Number Priority Date Filing Date Title
US10756408P 2008-10-22 2008-10-22
US61/107,564 2008-10-22
PCT/EP2009/063909 WO2010046443A2 (en) 2008-10-22 2009-10-22 Methods for detection and diagnosis of a bone or cartilage disorder

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JP2012506551A true JP2012506551A (ja) 2012-03-15
JP2012506551A5 JP2012506551A5 (enExample) 2012-11-15

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US (1) US20110189694A1 (enExample)
EP (1) EP2359145A2 (enExample)
JP (1) JP2012506551A (enExample)
CN (1) CN102203617A (enExample)
CA (1) CA2739159A1 (enExample)
WO (1) WO2010046443A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019513223A (ja) * 2016-03-25 2019-05-23 ユニベルシテ・ド・リエージュＵｎｉｖｅｒｓｉｔｅ Ｄｅ Ｌｉｅｇｅ 骨関節炎のバイオマーカーとしてのオステオモジュリン及びオステオモジュリンフラグメント、並びにそれらの使用
JP2025000999A (ja) * 2013-08-05 2025-01-07 イマティクス バイオテクノロジーズ ゲーエムベーハー Ｎｓｃｌｃをはじめとする肺がんなどの数種の腫瘍に対する新規免疫療法

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US9404932B2 (en) * 2007-11-05 2016-08-02 Nordic Bioscience A/S Pathology biomarker assay
GB201107922D0 (en) * 2011-05-12 2011-06-22 Nordic Bioscience As Biochemical markers for CVD risk assessment
JP5873652B2 (ja) * 2011-05-31 2016-03-01 国立大学法人京都大学 軟骨疾患治療薬のスクリーニング方法および軟骨疾患治療用改変軟骨細胞
CA2912266A1 (en) * 2013-05-14 2014-11-20 Lisbet HAGLUND Chondroadherin fragments as indicators of intervertebral disc degeneration
JP6420074B2 (ja) 2013-06-27 2018-11-07 国立大学法人京都大学 プテロシン誘導体を含む軟骨欠損、軟骨変性、および／または軟骨菲薄疾患治療剤
EP3233919B1 (en) * 2014-12-19 2020-11-25 Val-Chum, Limited Partnership Dicam-specific antibodies and uses thereof
US11560594B2 (en) 2015-02-05 2023-01-24 Duke University Methods of detecting osteoarthritis and predicting progression thereof
PT3388075T (pt) 2015-03-27 2023-08-18 Immatics Biotechnologies Gmbh Novos péptidos e combinações de péptidos para uso em imunoterapia contra vários tumores
GB201505305D0 (en) 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
CN106117357B (zh) * 2016-06-29 2019-08-30 烟台正海生物科技股份有限公司 Bmp-2抗体及其在检测骨修复材料中bmp-2蛋白含量中的应用
US10646540B2 (en) * 2016-11-18 2020-05-12 City Of Hope Peptide inhibitors of twist
CN107383176A (zh) * 2017-05-10 2017-11-24 于学杰 用于对汉滩病毒和汉城病毒引起的肾综合征出血热分型的多肽
AT521641B1 (de) * 2018-09-12 2020-07-15 Fianostics Gmbh Verfahren zur Diagnose von Lebererkrankungen
US20230212282A1 (en) * 2020-05-29 2023-07-06 New York Society for the Relief of the Ruptured and Crippled, maintaining the Hospital for Special Methods and compositions for treating, preventing the onset and/or slowing progression of osteoarthritis
CN118126974B (zh) * 2024-03-14 2025-04-11 江苏大学附属医院 骨关节炎标记物loxl1及其应用

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JP2005503533A (ja) * 2001-01-19 2005-02-03 ケンブリッジ サイエンティフィック， インコーポレイテッド 骨粗鬆症の診断方法および処置方法
WO2006014013A1 (ja) * 2004-08-04 2006-02-09 Riken 骨・関節疾患感受性遺伝子およびその用途
WO2006125973A2 (en) * 2005-05-23 2006-11-30 St George's Enterprises Limited Diagnosis of tuberculosis using gene expression marker analysis

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US4857456A (en) * 1985-04-30 1989-08-15 The Regents Of The University Of California Assay of Bone morphogenetic protein (BMP) and anti-BMP antibody for the diagnosis of bone disorders
US7189520B2 (en) * 2002-12-12 2007-03-13 Strategic Diagnostics Inc. Compositions and methods for detecting animal byproduct in feed
US8012950B2 (en) * 2003-08-29 2011-09-06 Wisconsin Alumni Research Foundation Method to diagnose and treat degenerative joint disease
WO2007045661A1 (en) * 2005-10-20 2007-04-26 Nordic Bioscience Diagnostics A/S Detection or quantification of aggrecan and its fragments
US20100081136A1 (en) * 2006-10-16 2010-04-01 Stefan Golz Crtac as a biomarker, therapeutic and diagnostic target
US8182998B2 (en) * 2007-04-26 2012-05-22 Genera Istrazivanja D.O.O. Blood biomarkers for bone fracture and cartilage injury

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JP2005503533A (ja) * 2001-01-19 2005-02-03 ケンブリッジ サイエンティフィック， インコーポレイテッド 骨粗鬆症の診断方法および処置方法
WO2006014013A1 (ja) * 2004-08-04 2006-02-09 Riken 骨・関節疾患感受性遺伝子およびその用途
WO2006125973A2 (en) * 2005-05-23 2006-11-30 St George's Enterprises Limited Diagnosis of tuberculosis using gene expression marker analysis

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JPN5012003201; ＬＯＲＥＮＺＯ　Ｐ: 'ＩＤＥＮＴＩＦＩＣＡＴＩＯＮ　ＡＮＤ　ＣＨＡＲＡＣＴＥＲＩＺＡＴＩＯＮ　ＯＦ　ＡＳＰＯＲＩＮ．　Ａ　ＮＯＶＥＬ　ＭＥＭＢＥＲ　ＯＦ　ＴＨＥ　ＬＥＵＣＩＮＥ-ＲＩＣＨ　以下備考' ＪＯＵＲＮＡＬ　ＯＦ　ＢＩＯＬＯＧＩＣＡＬ　ＣＨＥＭＩＳＴＲＹ Ｖ２７６　Ｎ１５, 20010413, Ｐ１２２０１-１２２１１, ＡＭＥＲＩＣＡＮ　ＳＯＣＩＥＴＹ　ＯＦ　ＢＩＯＣＨＥＭＩＣＡＬ　ＢＩＯＬＯＧＩＳＴＳ *
JPN6013049757; 水野守道: 'Ｃｈｏｎｄｒｏａｄｈｅｒｉｎの構造と機能，そして骨粗しょう症早期診断システムへの応用の可能性について' Ｏｓｔｅｏｐｏｒｏｓｉｓ Ｊｐｎ． Ｖｏｌ．６，Ｎｏ．３ （１９９８．１０）, 199810, Ｐ．６７７-６８２ *
JPN6014038330; 奴賀賢　ほか: 'エピフィカン／バイグリカンダブルノックアウトマウスは変形性関節症のモデルとなりうる' 日本整形外科学会雑誌 Ｖｏｌ．７７，Ｎｏ．８, 20030825, Ｐ．Ｓ９６０ *
JPN6014038331; 桃原茂樹ほか: '変形性膝関節軟骨におけるデルマタン硫酸プロテオグリカン代謝の検討-関節マーカーとしての可能性-' 日本整形外科学会雑誌 Ｖｏｌ．７７，Ｎｏ．８, 20030825, Ｐ．Ｓ９６１ *
JPN6014038332; 星和人、小沢英浩: '骨粗鬆症の生化学-非コラーゲン性蛋白を中心に-' Ｇｅｒｉａｔｒ．　Ｍｅｄ． Ｖｏｌ．４１，Ｎｏ．１１, 20031101, Ｐ．１５７９-１５８５ *
JPN6014038333; Ｍｉｃｈｅｌｌｅ　ＤＥＥＲＥ　ｅｔ　ａｌ．: 'Ｃｈａｒａｃｔｅｒｉｚａｔｉｏｎ　ｏｆ　ｈｕｍａｎ　ＤＳＰＧ３，　ａ　ｓｍａｌｌ　ｄｅｒｍａｔａｎ　ｓｕｌｆａｔｅ　ｐｒｏｔｅｏｇｌｙｃａｎ' Ｇｅｎｏｍｉｃｓ Ｖｏｌ．３８，Ｎｏ．３, 19961215, Ｐ．３９９-４０４ *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025000999A (ja) * 2013-08-05 2025-01-07 イマティクス バイオテクノロジーズ ゲーエムベーハー Ｎｓｃｌｃをはじめとする肺がんなどの数種の腫瘍に対する新規免疫療法
JP2019513223A (ja) * 2016-03-25 2019-05-23 ユニベルシテ・ド・リエージュＵｎｉｖｅｒｓｉｔｅ Ｄｅ Ｌｉｅｇｅ 骨関節炎のバイオマーカーとしてのオステオモジュリン及びオステオモジュリンフラグメント、並びにそれらの使用

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CA2739159A1 (en) 2010-04-29
US20110189694A1 (en) 2011-08-04
EP2359145A2 (en) 2011-08-24
CN102203617A (zh) 2011-09-28
WO2010046443A2 (en) 2010-04-29
WO2010046443A3 (en) 2010-08-12

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