JP2012506421A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012506421A5 JP2012506421A5 JP2011532774A JP2011532774A JP2012506421A5 JP 2012506421 A5 JP2012506421 A5 JP 2012506421A5 JP 2011532774 A JP2011532774 A JP 2011532774A JP 2011532774 A JP2011532774 A JP 2011532774A JP 2012506421 A5 JP2012506421 A5 JP 2012506421A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- amount
- present
- hib
- type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 44
- 102000036639 antigens Human genes 0.000 claims 44
- 108091007433 antigens Proteins 0.000 claims 44
- 238000002360 preparation method Methods 0.000 claims 13
- 229960005486 vaccine Drugs 0.000 claims 13
- 239000000203 mixture Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 9
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims 7
- 229960005323 phenoxyethanol Drugs 0.000 claims 7
- 201000005702 Pertussis Diseases 0.000 claims 6
- 206010043376 Tetanus Diseases 0.000 claims 5
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 claims 5
- 229940001442 combination vaccine Drugs 0.000 claims 5
- 206010013023 diphtheria Diseases 0.000 claims 5
- 239000007788 liquid Substances 0.000 claims 4
- 241000991587 Enterovirus C Species 0.000 claims 3
- 241000606768 Haemophilus influenzae Species 0.000 claims 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 3
- 239000002671 adjuvant Substances 0.000 claims 3
- 101000623895 Bos taurus Mucin-15 Proteins 0.000 claims 2
- 241000274177 Juniperus sabina Species 0.000 claims 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 2
- 229940024545 aluminum hydroxide Drugs 0.000 claims 2
- 229940047650 haemophilus influenzae Drugs 0.000 claims 2
- 208000006454 hepatitis Diseases 0.000 claims 2
- 231100000283 hepatitis Toxicity 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000003755 preservative agent Substances 0.000 claims 2
- 230000002335 preservative effect Effects 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 claims 1
- 102000014914 Carrier Proteins Human genes 0.000 claims 1
- 108010078791 Carrier Proteins Proteins 0.000 claims 1
- 101150047505 FIM1 gene Proteins 0.000 claims 1
- 101710154606 Hemagglutinin Proteins 0.000 claims 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 1
- 101710116435 Outer membrane protein Proteins 0.000 claims 1
- 101710176177 Protein A56 Proteins 0.000 claims 1
- SGSXWFDMRKAVLS-UHFFFAOYSA-N [6'-acetyloxy-5-[3-[3-[4-(1-methylindol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propylcarbamoyl]-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] acetate Chemical compound C1=C(C=2C(NC(=O)C=2C=2C3=CC=CC=C3N(C)C=2)=O)C2=CC=CC=C2N1CCCNC(=O)C(C=C1C(=O)O2)=CC=C1C12C2=CC=C(OC(C)=O)C=C2OC2=CC(OC(=O)C)=CC=C12 SGSXWFDMRKAVLS-UHFFFAOYSA-N 0.000 claims 1
- 229940024546 aluminum hydroxide gel Drugs 0.000 claims 1
- SMYKVLBUSSNXMV-UHFFFAOYSA-K aluminum;trihydroxide;hydrate Chemical compound O.[OH-].[OH-].[OH-].[Al+3] SMYKVLBUSSNXMV-UHFFFAOYSA-K 0.000 claims 1
- 201000006599 congenital myasthenic syndrome 4C Diseases 0.000 claims 1
- 229960003983 diphtheria toxoid Drugs 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 239000000185 hemagglutinin Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 108010021711 pertactin Proteins 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 229960000814 tetanus toxoid Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2438DE2008 | 2008-10-24 | ||
| IN2438/DEL/2008 | 2008-10-24 | ||
| PCT/IN2009/000600 WO2010046935A1 (en) | 2008-10-24 | 2009-10-23 | Combination vaccine with acellular pertussis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012506421A JP2012506421A (ja) | 2012-03-15 |
| JP2012506421A5 true JP2012506421A5 (cg-RX-API-DMAC7.html) | 2012-12-06 |
Family
ID=42119003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011532774A Pending JP2012506421A (ja) | 2008-10-24 | 2009-10-23 | 新規な無細胞百日咳ワクチン組成物およびその製造方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8551451B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2529749A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2012506421A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102196818A (cg-RX-API-DMAC7.html) |
| AP (1) | AP2011005701A0 (cg-RX-API-DMAC7.html) |
| AR (1) | AR073959A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0920630A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2741396A1 (cg-RX-API-DMAC7.html) |
| CL (1) | CL2011000914A1 (cg-RX-API-DMAC7.html) |
| CO (1) | CO6430434A2 (cg-RX-API-DMAC7.html) |
| MA (1) | MA32819B1 (cg-RX-API-DMAC7.html) |
| PE (1) | PE20100366A1 (cg-RX-API-DMAC7.html) |
| RU (2) | RU2526214C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010046935A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ575273A (en) | 2006-09-07 | 2012-02-24 | Glaxosmithkline Biolog Sa | Method for making combination vaccine comprising inactivated poliovirus type 1, diptheria toxoid and tetanus toxoid |
| GB0822633D0 (en) * | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
| RU2705163C2 (ru) * | 2011-01-05 | 2019-11-05 | Бхарат Байотек Интернэшнл Лимитед | Комбинированная семивалентная вакцина |
| FR2985663B1 (fr) * | 2012-01-17 | 2015-03-27 | Sanofi Pasteur | Procede de formulation d'un vaccin contenant au moins deux antigenes susceptibles de s'adsorber sur de l'oxy hydroxyde d'aluminium |
| FR2992656B1 (fr) * | 2012-07-02 | 2016-10-07 | Sanofi Pasteur | Procede de production d'antigenes haemophilus influenzae type b |
| DK2884996T3 (da) * | 2012-08-17 | 2020-03-09 | Intervet Int Bv | Immunogen sammensætning af dræbte leptospira-bakterier |
| MX362793B (es) | 2013-03-08 | 2019-02-13 | Janssen Vaccines & Prevention Bv | Vacuna acelular contra pertussis. |
| US9849066B2 (en) | 2013-04-24 | 2017-12-26 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
| BR112016002354A2 (pt) * | 2013-08-05 | 2017-09-12 | Glaxosmithkline Biologicals Sa | composição imunogênica, métodos para proteger um bebê contra infecção ou doença e para evocar uma resposta imune, regime de vacinação, e, kit |
| CN105861535B (zh) * | 2015-01-20 | 2019-10-25 | 中国人民解放军军事医学科学院生物工程研究所 | 伤寒糖蛋白的生物制备方法及其应用 |
| CN106075428A (zh) * | 2015-07-01 | 2016-11-09 | 北京科兴中维生物技术有限公司 | 一种免疫原性组合物及其制备方法 |
| JP7404226B2 (ja) * | 2017-07-18 | 2023-12-25 | セラム インスティテュート オブ インディア プライベート リミティド | 向上した安定性、高度の免疫原性、及び減少した反応源性を有する免疫原性組成物、並びにその調製プロセス |
| CN109550046B (zh) * | 2018-12-21 | 2020-08-25 | 北京民海生物科技有限公司 | 一种吸附无细胞百白破-脊髓灰质炎-b型流感嗜血杆菌联合疫苗及其制备方法 |
| WO2020165920A1 (en) * | 2019-02-12 | 2020-08-20 | Biological E Limited | Multivalent vaccine composition |
| CN110917344B (zh) * | 2019-12-26 | 2022-11-04 | 北京科兴中维生物技术有限公司 | 一种液体疫苗组合物及其应用 |
| CN111053898B (zh) * | 2019-12-26 | 2023-05-16 | 北京科兴中维生物技术有限公司 | 一种疫苗组合物及其应用 |
| WO2021176409A1 (en) | 2020-03-05 | 2021-09-10 | Sanofi Healthcare India Private Limited | Preservative combination for vaccine composition |
| US20240238298A1 (en) * | 2021-05-26 | 2024-07-18 | Emory University | JAK Inhibitors for Managing Conditions in Patients with Down's Syndrome or Other Trisomy |
| WO2025109417A1 (en) * | 2023-11-21 | 2025-05-30 | Panacea Biotec Limited | Immunogenic composition of haemophilus influenzae conjugated to protein d |
| CN119524117B (zh) * | 2025-01-23 | 2025-09-23 | 康希诺生物股份公司 | 免疫原性组合物、百白破联合疫苗及其制备方法和应用 |
| CN119548620B (zh) * | 2025-01-23 | 2025-09-12 | 康希诺生物股份公司 | 一种用于预防白喉、百日咳和破伤风的免疫原性组合物、疫苗及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0642355B1 (en) | 1992-05-23 | 1998-07-15 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Combined vaccines comprising hepatitis b surface antigen and other antigens |
| US5877298A (en) | 1995-05-04 | 1999-03-02 | Connaught Lab | Acellular pertussis vaccines and methods of preparing thereof |
| FR2734484B1 (fr) | 1995-05-24 | 1997-06-27 | Pasteur Merieux Serums Vacc | Composition vaccinale liquide et procede de fabrication |
| US20020054884A1 (en) | 1995-06-23 | 2002-05-09 | Smithkline Beecham Biologicals, Sa | Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate |
| CN100408095C (zh) * | 1996-07-02 | 2008-08-06 | 康诺特实验室有限公司 | 多价dtp-polio疫苗 |
| DE69735191T2 (de) | 1997-09-15 | 2006-10-05 | Sanofi Pasteur Msd | Verfahren zur Herstellung multivalenter Impfstoffe |
| GB9806456D0 (en) | 1998-03-25 | 1998-05-27 | Smithkline Beecham Biolog | Vaccine composition |
| GB0313916D0 (en) | 2003-06-16 | 2003-07-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
| GB0405787D0 (en) | 2004-03-15 | 2004-04-21 | Chiron Srl | Low dose vaccines |
| JP5135220B2 (ja) * | 2005-09-01 | 2013-02-06 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー | 血清群ｃ髄膜炎菌を含む複数ワクチン接種 |
| US20070065462A1 (en) * | 2005-09-21 | 2007-03-22 | Ryall Robert P | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine |
| GB0522765D0 (en) | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
-
2009
- 2009-10-22 PE PE2009001196A patent/PE20100366A1/es not_active Application Discontinuation
- 2009-10-23 US US13/125,708 patent/US8551451B2/en not_active Expired - Fee Related
- 2009-10-23 BR BRPI0920630A patent/BRPI0920630A2/pt not_active Application Discontinuation
- 2009-10-23 AR ARP090104080A patent/AR073959A1/es not_active Application Discontinuation
- 2009-10-23 CA CA2741396A patent/CA2741396A1/en not_active Abandoned
- 2009-10-23 WO PCT/IN2009/000600 patent/WO2010046935A1/en not_active Ceased
- 2009-10-23 AP AP2011005701A patent/AP2011005701A0/xx unknown
- 2009-10-23 EP EP11172591.7A patent/EP2529749A1/en not_active Withdrawn
- 2009-10-23 CN CN200980142461XA patent/CN102196818A/zh active Pending
- 2009-10-23 JP JP2011532774A patent/JP2012506421A/ja active Pending
- 2009-10-23 RU RU2011120308/10A patent/RU2526214C2/ru active
- 2009-10-23 EP EP09821706A patent/EP2362781A4/en not_active Withdrawn
-
2011
- 2011-04-21 CL CL2011000914A patent/CL2011000914A1/es unknown
- 2011-05-20 MA MA33875A patent/MA32819B1/fr unknown
- 2011-05-24 CO CO11063979A patent/CO6430434A2/es not_active Application Discontinuation
-
2013
- 2013-01-14 RU RU2013101418A patent/RU2634393C2/ru active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012506421A5 (cg-RX-API-DMAC7.html) | ||
| RU2013101418A (ru) | Комбинированная вакцина с ацеллюлярным коклюшем | |
| JP2020527571A5 (cg-RX-API-DMAC7.html) | ||
| RU2008112289A (ru) | Множественная вакцинация, включающая менингококки серогруппы с | |
| JP5637848B2 (ja) | 髄膜炎ワクチンの製剤化 | |
| EP0833662B1 (en) | A vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate | |
| JP2009525260A5 (cg-RX-API-DMAC7.html) | ||
| HRP20110431T1 (hr) | Kombinirano cjepivo od inaktiviranog poliovirusa | |
| RU2011135761A (ru) | Комбинированная вакцина с цельноклеточным коклюшем | |
| WO1999048525A1 (en) | Hib/dtpa vaccine composition and methods of preparation | |
| JP2004501873A5 (cg-RX-API-DMAC7.html) | ||
| JP2010529103A5 (cg-RX-API-DMAC7.html) | ||
| JP2015034178A (ja) | 全細胞百日咳抗原を含む混合ワクチン | |
| RU2016150422A (ru) | Комбинированная семивалентная вакцина | |
| RU2008123006A (ru) | Получение вакцин, содержащих поверхностный антиген вируса гепатита в и поверхностно-активное вещество | |
| RU2006142156A (ru) | Объединенные менингококковые конъюгаты с общим белком-носителем | |
| JP2015531389A5 (cg-RX-API-DMAC7.html) | ||
| RU2015106745A (ru) | Иммуногенные композиции | |
| CA2855224A1 (en) | Fermentation media free of animal-derived components for production of diphtheria toxoids suitable for human vaccine use | |
| JP2022502469A (ja) | 低減用量の不活化ポリオウイルスを含む混合ワクチン組成物およびそれを調製するための方法 | |
| JP2015509963A5 (cg-RX-API-DMAC7.html) | ||
| JP2024009899A (ja) | 多価ワクチン組成物 | |
| CA2434421C (en) | Manufacturing method of combined vaccine | |
| CN109550046B (zh) | 一种吸附无细胞百白破-脊髓灰质炎-b型流感嗜血杆菌联合疫苗及其制备方法 | |
| CN104906569A (zh) | 一种百日咳疫苗制剂及其联合疫苗 |