JP2012506257A - 細胞および細胞由来生成物の産生のための、灌流バイオリアクター、細胞培養システム、および方法 - Google Patents

細胞および細胞由来生成物の産生のための、灌流バイオリアクター、細胞培養システム、および方法 Download PDF

Info

Publication number
JP2012506257A
JP2012506257A JP2011533338A JP2011533338A JP2012506257A JP 2012506257 A JP2012506257 A JP 2012506257A JP 2011533338 A JP2011533338 A JP 2011533338A JP 2011533338 A JP2011533338 A JP 2011533338A JP 2012506257 A JP2012506257 A JP 2012506257A
Authority
JP
Japan
Prior art keywords
cell
cells
cell culture
bioreactor
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011533338A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012506257A5 (enExample
Inventor
マーク ハーシェル
ダレル ペイジ
ロバート ウォイチェホフスキ
Original Assignee
バイオベスト インターナショナル インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイオベスト インターナショナル インコーポレイテッド filed Critical バイオベスト インターナショナル インコーポレイテッド
Publication of JP2012506257A publication Critical patent/JP2012506257A/ja
Publication of JP2012506257A5 publication Critical patent/JP2012506257A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2011533338A 2008-10-22 2009-10-22 細胞および細胞由来生成物の産生のための、灌流バイオリアクター、細胞培養システム、および方法 Withdrawn JP2012506257A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10764408P 2008-10-22 2008-10-22
US61/107,644 2008-10-22
PCT/US2009/061700 WO2010048417A2 (en) 2008-10-22 2009-10-22 Perfusion bioreactors, cell culture systems, and methods for production of cells and cell-derived products

Publications (2)

Publication Number Publication Date
JP2012506257A true JP2012506257A (ja) 2012-03-15
JP2012506257A5 JP2012506257A5 (enExample) 2012-12-06

Family

ID=42119984

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011533338A Withdrawn JP2012506257A (ja) 2008-10-22 2009-10-22 細胞および細胞由来生成物の産生のための、灌流バイオリアクター、細胞培養システム、および方法

Country Status (7)

Country Link
US (1) US20110212493A1 (enExample)
EP (1) EP2346984A4 (enExample)
JP (1) JP2012506257A (enExample)
AU (1) AU2009308354A1 (enExample)
CA (1) CA2741481A1 (enExample)
IL (1) IL212387A0 (enExample)
WO (1) WO2010048417A2 (enExample)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015526094A (ja) * 2012-08-20 2015-09-10 テルモ ビーシーティー、インコーポレーテッド 細胞成長チャンバーを循環する流体の成分を濃縮する方法
WO2016093321A1 (ja) * 2014-12-11 2016-06-16 株式会社アイカムス・ラボ 細胞培養方法及び細胞培養装置
JP2017513512A (ja) * 2014-04-28 2017-06-01 ビババイオセル エスピーエー 自動細胞培養及び回収装置
JP2018023289A (ja) * 2016-08-08 2018-02-15 株式会社カネカ 細胞培養容器、これを用いた細胞培養システム、および細胞培養方法
WO2020013221A1 (ja) * 2018-07-12 2020-01-16 日本曹達株式会社 培養装置、担体、および培養対象回収方法
JP2020043808A (ja) * 2018-09-18 2020-03-26 テルモ株式会社 バイオリアクタ、細胞培養システム及び細胞培養方法
JP2020043809A (ja) * 2018-09-18 2020-03-26 テルモ株式会社 バイオリアクタ、細胞培養システム及び細胞培養方法
WO2021038997A1 (ja) * 2019-08-29 2021-03-04 ファナック株式会社 細胞製造装置
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
WO2021107450A1 (ko) * 2019-11-29 2021-06-03 주식회사 아모그린텍 세포배양장치
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11608486B2 (en) 2015-07-02 2023-03-21 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
JP2023521726A (ja) * 2020-04-10 2023-05-25 サウスウエスト リサーチ インスティテュート ウイルスベクター産生のための3次元バイオリアクター
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
JP2025029059A (ja) * 2018-12-21 2025-03-05 ロンザ ウォーカーズヴィル,インコーポレーテッド ウイルスベクターの自動産生方法
JP7905882B2 (ja) 2020-04-10 2026-08-17 サウスウエスト リサーチ インスティテュート ウイルスベクター産生のための3次元バイオリアクター

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE496987T1 (de) 2006-05-22 2011-02-15 Biovest Int Inc Ausserkapilläres fluidzirkulationssystem und - verfahren
EP2609189A4 (en) * 2010-08-24 2015-08-05 Hawley & Hazel Chemical Co Zhongshan Ltd METHODS, DEVICES AND USES RELATED TO BIOFILMS
US9725689B2 (en) 2010-10-08 2017-08-08 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2012079086A2 (en) * 2010-12-10 2012-06-14 Florida State University Research Foundation, Inc. Mesenchymal stem cells (msc) expansion methods and materials
EP2714886B1 (en) * 2011-05-30 2020-01-22 Atech Partners Ltd. Bioreactor system for continuous cell cultivation
WO2012171030A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Method and apparatus for antibody production and purification
WO2012171026A2 (en) * 2011-06-10 2012-12-13 Biovest International, Inc. Methods for high yield virus production
US10989362B2 (en) 2011-10-07 2021-04-27 Pall Technology Uk Limited Fluid processing control system and related methods
US9683207B2 (en) 2012-05-01 2017-06-20 FiberCell Production Solutions LLC Method for growing cells in hollow fibers
CA2920957A1 (en) * 2012-08-28 2014-03-06 Biovest International, Inc. Biomanufacturing suite and methods for large-scale production of cells, viruses, and biomolecules
WO2014036488A1 (en) 2012-08-31 2014-03-06 Biovest International, Inc. Methods for producing high-fidelity autologous idiotype vaccines
US9512393B2 (en) 2012-09-06 2016-12-06 Pluristem Ltd. Devices and methods for culture of cells
EP2706112A1 (en) * 2012-09-06 2014-03-12 Université Catholique De Louvain Fluidic device for studying of surface-dwelling multicellular layers and microbial biofilms
ES2489315B1 (es) * 2013-01-16 2015-09-09 Fundación Para La Investigación Biomédica Del Hospital Universitario La Paz Cámara de cultivo celular sobre biomateriales
CN105143443A (zh) 2013-02-22 2015-12-09 建新公司 微载体灌注培养方法及其用途
US10900023B2 (en) 2013-08-22 2021-01-26 University of Pittsburgh—of the Commonwealth System of Higher Education Modular, microfluidic, mechanically active bioreactor for 3D, multi-tissue, tissue culture
WO2015048712A2 (en) * 2013-09-30 2015-04-02 Weyerhaeuser Nr Company Independent ports in automated bioreactor system
EP3068867B1 (en) 2013-11-16 2018-04-18 Terumo BCT, Inc. Expanding cells in a bioreactor
EP3105311A1 (en) 2014-02-10 2016-12-21 Univercells NV System, apparatus and method for biomolecules production
US20160361476A1 (en) * 2014-02-28 2016-12-15 Bdbc Sciences Corp. System for tissue manipulation
US10039244B2 (en) * 2014-03-04 2018-08-07 Greenonyx Ltd Systems and methods for cultivating and distributing aquatic organisms
TWI743024B (zh) * 2014-06-06 2021-10-21 美商健臻公司 灌注培養方法及其用途
EP3198006B1 (en) 2014-09-26 2021-03-24 Terumo BCT, Inc. Scheduled feed
US11154858B2 (en) 2015-10-06 2021-10-26 University of Pittsburgh—of the Commonwealth System of Higher Education Microfluidic tissue development systems
EP3365425A1 (en) 2015-10-20 2018-08-29 Locus Solutions LLC Apparatus, systems and methods for growing miroorganisms
WO2017087535A1 (en) * 2015-11-17 2017-05-26 Oregon State University Bio-lamina bioreactors and methods of making and using the same
SG11201806310TA (en) * 2016-01-26 2018-08-30 Boehringer Ingelheim Int Linked perfusion to continuous-flow stirred-tank reactor cell culture system
GB2554635A (en) * 2016-08-03 2018-04-11 Northwick Park Institute For Medical Res Ltd Bioreactors and methods for processing biological material
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
TWI675696B (zh) * 2017-06-01 2019-11-01 美商Emd密理博公司 用於灌注應用之切向流過濾裝置
KR102176500B1 (ko) 2017-07-21 2020-11-09 포항공과대학교 산학협력단 관류식 바이오 리액터를 사용한 세포밖 소포체 분비량 향상 방법 및 이를 위한 시스템
US11680241B2 (en) 2018-02-08 2023-06-20 University Of Florida Research Foundation, Inc. Perfusion enabled bioreactors
IL263127B (en) * 2018-11-19 2022-07-01 The Interdisciplinary Center Herzliya Cc A liquid-based biological system
CN113728085B (zh) 2019-02-05 2025-07-04 康宁股份有限公司 织造细胞培养基材
IL288338B2 (en) 2019-05-28 2023-02-01 Upside Foods Inc Apparatuses and methods for preparing a comestible meat product
EP4004180A4 (en) * 2019-07-29 2023-09-06 VitroLabs Inc SCALABLE BIOREACTOR SYSTEMS AND TISSUE GROWING METHODS
US11118151B2 (en) 2019-11-05 2021-09-14 Corning Incorporated Fixed bed bioreactor and methods of using the same
MX2022006095A (es) 2019-11-20 2022-08-16 Upside Foods Inc Aparatos y sistemas para preparar un producto carnico.
CN114945661A (zh) * 2019-11-27 2022-08-26 康宁股份有限公司 径向流固定床生物反应器及其使用方法
USD961115S1 (en) * 2020-01-20 2022-08-16 Adva Biotechnology Ltd. Bioreactor cabinet
CN116194569A (zh) * 2020-08-17 2023-05-30 东北大学 用于金属纳米颗粒生产的微生物辅助灌流系统
CN116601282A (zh) 2020-10-09 2023-08-15 康宁股份有限公司 表面改性的细胞培养基材和改性细胞培养基材的方法
EP4314244B1 (en) 2021-03-23 2025-07-23 Terumo BCT, Inc. Cell capture and expansion
US11752509B2 (en) 2021-06-17 2023-09-12 Upside Foods, Inc. Fluid dispenser for recovering material from a surface
US12606788B2 (en) 2021-09-01 2026-04-21 Global Life Sciences Solutions Usa Llc Perfusion filter membrane assembly
US20230066039A1 (en) * 2021-09-01 2023-03-02 Global Life Sciences Solutions Usa Llc Perfusion filter membrane and method of use
US12241050B2 (en) 2021-09-01 2025-03-04 Global Life Sciences Solutions Usa, Llc Perfusion filter assembly for increased cross flow
WO2023121655A1 (en) * 2021-12-21 2023-06-29 Bayer Aktiengesellschaft Improved cell culture method
WO2023164273A1 (en) * 2022-02-28 2023-08-31 University Of Georgia Research Foundation, Inc. Bioreactor for cell expansion and cultivation
US12152699B2 (en) 2022-02-28 2024-11-26 Terumo Bct, Inc. Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device
WO2024073071A1 (en) * 2022-09-29 2024-04-04 The University Of Akron Chamber assembly for ex-vivo electroretinogram with filleted perfusion inlet and outlet
US11981884B2 (en) 2022-10-17 2024-05-14 Upside Foods, Inc. Pipe-based bioreactors for producing comestible meat products and methods of using the same
WO2026046948A1 (en) * 2024-08-26 2026-03-05 Qorium B.V. Perfusion bioreactor, scaffold cassette, and method for culturing cells

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804628A (en) * 1984-10-09 1989-02-14 Endotronics, Inc. Hollow fiber cell culture device and method of operation
US5266476A (en) * 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US5786215A (en) * 1987-05-20 1998-07-28 Baxter International Inc. Method for culturing animal cells
DE3923279A1 (de) * 1989-07-14 1990-01-18 Will W Prof Dr Minuth Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivieren
US5126269A (en) * 1990-09-13 1992-06-30 Life Techologies, Inc. Spin filter perfusion bioreactor (sfpb) cell culture apparatus
BE1009306A5 (fr) * 1995-04-28 1997-02-04 Baxter Int Bioreacteur.
EP1181355A4 (en) * 1997-01-16 2005-05-04 Yissum Res Dev Co METHOD AND DEVICE FOR REALIZING A BIOLOGICAL MODIFICATION OF A FLUID
AU7172598A (en) * 1997-05-07 1998-11-27 Baxter International Inc. Method and apparatus for high volume production of viral particles
US6943008B1 (en) * 2002-08-21 2005-09-13 Florida State University Research Foundation, Inc. Bioreactor for cell culture
US6875605B1 (en) * 2002-08-21 2005-04-05 Florida State University Research Foundation, Inc. Modular cell culture bioreactor and associated methods
US7534601B2 (en) * 2002-08-27 2009-05-19 Vanderbilt University Capillary perfused bioreactors with multiple chambers
CN101120083B (zh) * 2003-10-08 2013-03-27 威尔森沃尔夫制造公司 利用透气性材料进行细胞培养的方法及装置
US7767446B2 (en) * 2004-09-16 2010-08-03 Becton, Dickinson And Company Perfusion bioreactors for culturing cells
JP4639799B2 (ja) * 2004-12-27 2011-02-23 カシオ計算機株式会社 カメラ装置、レンズ駆動方法
WO2007071072A1 (en) * 2005-12-22 2007-06-28 Corporation De L'ecole Polytechnique De Montreal High-rate perfusion bioreactor
ATE496987T1 (de) * 2006-05-22 2011-02-15 Biovest Int Inc Ausserkapilläres fluidzirkulationssystem und - verfahren

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015526094A (ja) * 2012-08-20 2015-09-10 テルモ ビーシーティー、インコーポレーテッド 細胞成長チャンバーを循環する流体の成分を濃縮する方法
US11795432B2 (en) 2014-03-25 2023-10-24 Terumo Bct, Inc. Passive replacement of media
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
JP2017513512A (ja) * 2014-04-28 2017-06-01 ビババイオセル エスピーエー 自動細胞培養及び回収装置
WO2016093321A1 (ja) * 2014-12-11 2016-06-16 株式会社アイカムス・ラボ 細胞培養方法及び細胞培養装置
JPWO2016093321A1 (ja) * 2014-12-11 2017-11-16 株式会社アイカムス・ラボ 細胞培養方法及び細胞培養装置
US11608486B2 (en) 2015-07-02 2023-03-21 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11634677B2 (en) 2016-06-07 2023-04-25 Terumo Bct, Inc. Coating a bioreactor in a cell expansion system
JP2018023289A (ja) * 2016-08-08 2018-02-15 株式会社カネカ 細胞培養容器、これを用いた細胞培養システム、および細胞培養方法
US11702634B2 (en) 2017-03-31 2023-07-18 Terumo Bct, Inc. Expanding cells in a bioreactor
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
WO2020013221A1 (ja) * 2018-07-12 2020-01-16 日本曹達株式会社 培養装置、担体、および培養対象回収方法
JP2020043809A (ja) * 2018-09-18 2020-03-26 テルモ株式会社 バイオリアクタ、細胞培養システム及び細胞培養方法
JP2020043808A (ja) * 2018-09-18 2020-03-26 テルモ株式会社 バイオリアクタ、細胞培養システム及び細胞培養方法
JP7133409B2 (ja) 2018-09-18 2022-09-08 テルモ株式会社 バイオリアクタ、細胞培養システム及び細胞培養方法
JP7133410B2 (ja) 2018-09-18 2022-09-08 テルモ株式会社 バイオリアクタ、細胞培養システム及び細胞培養方法
JP2025029059A (ja) * 2018-12-21 2025-03-05 ロンザ ウォーカーズヴィル,インコーポレーテッド ウイルスベクターの自動産生方法
CN114341337A (zh) * 2019-08-29 2022-04-12 发那科株式会社 细胞制造装置
JP7297272B2 (ja) 2019-08-29 2023-06-26 ファナック株式会社 細胞製造装置
JPWO2021038997A1 (enExample) * 2019-08-29 2021-03-04
WO2021038997A1 (ja) * 2019-08-29 2021-03-04 ファナック株式会社 細胞製造装置
KR102417445B1 (ko) * 2019-11-29 2022-07-06 주식회사 아모그린텍 세포배양장치
KR20210067562A (ko) * 2019-11-29 2021-06-08 주식회사 아모그린텍 세포배양장치
WO2021107450A1 (ko) * 2019-11-29 2021-06-03 주식회사 아모그린텍 세포배양장치
JP2023521726A (ja) * 2020-04-10 2023-05-25 サウスウエスト リサーチ インスティテュート ウイルスベクター産生のための3次元バイオリアクター
JP7905882B2 (ja) 2020-04-10 2026-08-17 サウスウエスト リサーチ インスティテュート ウイルスベクター産生のための3次元バイオリアクター

Also Published As

Publication number Publication date
WO2010048417A3 (en) 2010-08-19
WO2010048417A2 (en) 2010-04-29
AU2009308354A1 (en) 2010-04-29
EP2346984A4 (en) 2013-10-30
US20110212493A1 (en) 2011-09-01
IL212387A0 (en) 2011-06-30
CA2741481A1 (en) 2010-04-29
EP2346984A2 (en) 2011-07-27

Similar Documents

Publication Publication Date Title
US20110212493A1 (en) Perfusion bioreactors, cell culture systems, and methods for production of cells and cell-derived products
US10662401B2 (en) Biomanufacturing suite and methods for large-scale production of cells, viruses, and biomolecules
JP6586407B2 (ja) 自動的な組織工学モジュール
US20070122904A1 (en) Method and apparatus for culturing cells
US20210062147A1 (en) Method of manufacturing or differentiating mammalian pluripotent stem cellsor progenitor cells using a hollow fiber bioreactor
JPH078274A (ja) 膜バイオリアクター中の物質移動を改良する方法及び装置
JP2019528087A (ja) バイオリアクタおよびその使用法
CN117957304A (zh) 用于从细胞生产培养的肉类、组织和相关产品的系统
JP2019514402A (ja) 自動化された製造及び収集
CN1373800A (zh) 一种进行液体的生物学改变的装置和方法
WO2001023520A1 (en) Method and apparatus for culturing cells
JP2025522935A (ja) 乳汁分泌のための乳腺細胞型の拍動流培養
CN211035948U (zh) 一种模块化三维灌注细胞培养系统
Goltry et al. Large-scale production of adult stem cells for clinical use
CN110669669A (zh) 一种模块化三维灌注细胞培养系统
Taya et al. 2.27 Bioreactors for Animal Cell Cultures
AU781265B2 (en) Method and apparatus for culturing cells
Badhe et al. Design and functioning of new flow chamber bioreactor for skin tissue engineering applications

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121019

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20121019

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20130920

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20130926

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20130920