JP2012503674A - 抗癌剤との補助的治療薬としての下垂体アデニル酸シクラーゼ活性化ポリペプチド(pacap)及びpacap類似体の使用 - Google Patents
抗癌剤との補助的治療薬としての下垂体アデニル酸シクラーゼ活性化ポリペプチド(pacap)及びpacap類似体の使用 Download PDFInfo
- Publication number
- JP2012503674A JP2012503674A JP2011529275A JP2011529275A JP2012503674A JP 2012503674 A JP2012503674 A JP 2012503674A JP 2011529275 A JP2011529275 A JP 2011529275A JP 2011529275 A JP2011529275 A JP 2011529275A JP 2012503674 A JP2012503674 A JP 2012503674A
- Authority
- JP
- Japan
- Prior art keywords
- pacap
- compound
- subject
- administered
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19416608P | 2008-09-25 | 2008-09-25 | |
| US61/194,166 | 2008-09-25 | ||
| PCT/US2009/058445 WO2010036936A2 (en) | 2008-09-25 | 2009-09-25 | Use of pituitary adenylate cyclase-activating polypeptide (pacap) and pacap analogs as adjunctive treatments with anticancer agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012503674A true JP2012503674A (ja) | 2012-02-09 |
| JP2012503674A5 JP2012503674A5 (enExample) | 2013-11-28 |
Family
ID=42060409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011529275A Pending JP2012503674A (ja) | 2008-09-25 | 2009-09-25 | 抗癌剤との補助的治療薬としての下垂体アデニル酸シクラーゼ活性化ポリペプチド(pacap)及びpacap類似体の使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110268789A1 (enExample) |
| EP (1) | EP2337577A4 (enExample) |
| JP (1) | JP2012503674A (enExample) |
| CN (1) | CN102215859B (enExample) |
| AU (1) | AU2009296456B2 (enExample) |
| CA (1) | CA2738549A1 (enExample) |
| WO (1) | WO2010036936A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5908406B2 (ja) | 2009-11-02 | 2016-04-26 | ジ アドミニストレーターズ オブ ザ トゥレーン エデュケーショナル ファンド | 下垂体アデニル酸シクラーゼ活性化ポリペプチド(pacap)の類似体およびその使用方法 |
| CA2788835A1 (en) * | 2010-02-05 | 2011-08-11 | The Administrators Of The Tulane Educational Fund | The use of pituitary adenylate cyclase-activating polypeptide (pacap) and pacap analogs as adjunctive treatments with inhibitors of calcineurin or inhibitors of the mammalian target of rapamycin (mtor) complexes |
| US9353171B2 (en) * | 2011-11-17 | 2016-05-31 | The Administrators Of The Tulane Educational Fund | Use of pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP analogs for treating contrast-induced nephropathy |
| CN103145851B (zh) * | 2013-02-22 | 2014-07-02 | 暨南大学 | 重组蛋白PACAP38-NtA及其编码基因与应用 |
| WO2018129200A2 (en) | 2017-01-05 | 2018-07-12 | The Regents Of The University Of California | Pac1 receptor agonists (maxcaps) and uses thereof |
| ES2677242B1 (es) * | 2017-01-31 | 2019-03-27 | Univ Alcala Henares | Nanoconjugados formados por moléculas dendríticas y péptidos como agentes antitumorales frente al cáncer |
| JP7695772B2 (ja) * | 2017-11-14 | 2025-06-19 | 千寿製薬株式会社 | Pacapの安定化ペプチド |
| JPWO2020230869A1 (enExample) * | 2019-05-14 | 2020-11-19 | ||
| DE102024001175A1 (de) * | 2024-04-04 | 2025-10-09 | ReViSan Healthcare GmbH | Zubereitung zur Behandlung von entzündlichen Erkrankungen der Atemwege. |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005538942A (ja) * | 2002-05-03 | 2005-12-22 | ニューロノヴァ アーベー | 成体の神経幹又は前駆体細胞に関するpacap、vip及びマキサディランの機能的役割及び治療への使用可能性 |
| JP2008501723A (ja) * | 2004-06-11 | 2008-01-24 | ベクタス・バイオシステムズ・リミテッド | 循環器病の治療のための組成物および方法 |
| JP2008507540A (ja) * | 2004-07-21 | 2008-03-13 | チューレン ユニバーシティ ヘルス サイエンス センター | Pacap化合物を用いる腎臓機能障害及び多発性骨髄腫の治療 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008303956A1 (en) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Proadrenomedullin alone or in combination with big gastrin I as a therapeutic agent |
-
2009
- 2009-09-25 AU AU2009296456A patent/AU2009296456B2/en not_active Ceased
- 2009-09-25 CA CA2738549A patent/CA2738549A1/en not_active Abandoned
- 2009-09-25 US US13/120,862 patent/US20110268789A1/en not_active Abandoned
- 2009-09-25 JP JP2011529275A patent/JP2012503674A/ja active Pending
- 2009-09-25 WO PCT/US2009/058445 patent/WO2010036936A2/en not_active Ceased
- 2009-09-25 EP EP09816932A patent/EP2337577A4/en not_active Withdrawn
- 2009-09-25 CN CN200980145368.4A patent/CN102215859B/zh not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005538942A (ja) * | 2002-05-03 | 2005-12-22 | ニューロノヴァ アーベー | 成体の神経幹又は前駆体細胞に関するpacap、vip及びマキサディランの機能的役割及び治療への使用可能性 |
| JP2008501723A (ja) * | 2004-06-11 | 2008-01-24 | ベクタス・バイオシステムズ・リミテッド | 循環器病の治療のための組成物および方法 |
| JP2008507540A (ja) * | 2004-07-21 | 2008-03-13 | チューレン ユニバーシティ ヘルス サイエンス センター | Pacap化合物を用いる腎臓機能障害及び多発性骨髄腫の治療 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009296456A1 (en) | 2010-04-01 |
| WO2010036936A9 (en) | 2010-07-15 |
| EP2337577A1 (en) | 2011-06-29 |
| WO2010036936A2 (en) | 2010-04-01 |
| CN102215859B (zh) | 2016-04-20 |
| CN102215859A (zh) | 2011-10-12 |
| US20110268789A1 (en) | 2011-11-03 |
| EP2337577A4 (en) | 2012-08-15 |
| AU2009296456B2 (en) | 2016-06-16 |
| CA2738549A1 (en) | 2010-04-01 |
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Legal Events
| Date | Code | Title | Description |
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| A521 | Request for written amendment filed |
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| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
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| A912 | Re-examination (zenchi) completed and case transferred to appeal board |
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