JP2012503025A - 精製されたポリペプチド組成物を調製するための方法 - Google Patents
精製されたポリペプチド組成物を調製するための方法 Download PDFInfo
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- JP2012503025A JP2012503025A JP2011528083A JP2011528083A JP2012503025A JP 2012503025 A JP2012503025 A JP 2012503025A JP 2011528083 A JP2011528083 A JP 2011528083A JP 2011528083 A JP2011528083 A JP 2011528083A JP 2012503025 A JP2012503025 A JP 2012503025A
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- amino acid
- peptidomimetic macrocycle
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- peptidomimetic
- macrocycle
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| JP2019153604A Pending JP2019214614A (ja) | 2008-09-22 | 2019-08-26 | 精製されたポリペプチド組成物を調製するための方法 |
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| JP2015509940A (ja) * | 2012-02-15 | 2015-04-02 | エイルロン セラピューティクス，インコーポレイテッド | ペプチドミメティック大環状化合物 |
| JP2016537413A (ja) * | 2013-10-28 | 2016-12-01 | ノーレックス インコーポレイテッド | Ｎｍｄａ受容体モジュレーター及びプロドラッグ、塩、並びにこれらの使用 |
| JP2017513826A (ja) * | 2014-04-02 | 2017-06-01 | ユニバーシティー オブ ロチェスター | アルファヘリックスを模倣した大環状ペプチドミメティック |
| US10023613B2 (en) | 2015-09-10 | 2018-07-17 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles as modulators of MCL-1 |
| US10202431B2 (en) | 2007-01-31 | 2019-02-12 | Aileron Therapeutics, Inc. | Stabilized P53 peptides and uses thereof |
| US10227380B2 (en) | 2012-02-15 | 2019-03-12 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| US10246491B2 (en) | 2013-03-06 | 2019-04-02 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and use thereof in regulating HIF1alpha |
| US10253067B2 (en) | 2015-03-20 | 2019-04-09 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| US10301351B2 (en) | 2007-03-28 | 2019-05-28 | President And Fellows Of Harvard College | Stitched polypeptides |
| US10308699B2 (en) | 2011-10-18 | 2019-06-04 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| US10471120B2 (en) | 2014-09-24 | 2019-11-12 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| US10703780B2 (en) | 2010-08-13 | 2020-07-07 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| US10905739B2 (en) | 2014-09-24 | 2021-02-02 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
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| US7981998B2 (en) * | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
| CN105061577A (zh) * | 2006-12-14 | 2015-11-18 | 爱勒让治疗公司 | 双巯基大环化系统 |
| TWI433674B (zh) | 2006-12-28 | 2014-04-11 | Infinity Discovery Inc | 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類 |
| CN109627287A (zh) * | 2007-02-23 | 2019-04-16 | 爱勒让治疗公司 | 三唑大环系统 |
| CA2710858A1 (en) | 2007-12-27 | 2009-07-09 | Infinity Pharmaceuticals, Inc. | Methods for stereoselective reduction |
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| US10905739B2 (en) | 2014-09-24 | 2021-02-02 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
| US10253067B2 (en) | 2015-03-20 | 2019-04-09 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| US10023613B2 (en) | 2015-09-10 | 2018-07-17 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles as modulators of MCL-1 |
Also Published As
| Publication number | Publication date |
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| US20160115204A1 (en) | 2016-04-28 |
| EP2342221B1 (en) | 2018-11-07 |
| US20120264674A1 (en) | 2012-10-18 |
| AU2009294875C1 (en) | 2015-05-14 |
| IL254498A0 (en) | 2017-11-30 |
| US20100210515A1 (en) | 2010-08-19 |
| US9394336B2 (en) | 2016-07-19 |
| CA2737921C (en) | 2019-01-15 |
| BRPI0918838A2 (pt) | 2015-12-08 |
| WO2010034032A3 (en) | 2010-05-20 |
| US9206223B2 (en) | 2015-12-08 |
| JP2019214614A (ja) | 2019-12-19 |
| EP2342221A2 (en) | 2011-07-13 |
| WO2010034032A2 (en) | 2010-03-25 |
| AU2009294875B2 (en) | 2014-12-04 |
| JP2020015748A (ja) | 2020-01-30 |
| IL211837A0 (en) | 2011-06-30 |
| IL211837A (en) | 2017-09-28 |
| JP2015110654A (ja) | 2015-06-18 |
| CN104961795A (zh) | 2015-10-07 |
| JP6196640B2 (ja) | 2017-09-13 |
| US20220017569A1 (en) | 2022-01-20 |
| AU2009294875A1 (en) | 2010-03-25 |
| CN102203126A (zh) | 2011-09-28 |
| IL254498B (en) | 2020-02-27 |
| EP3492492A1 (en) | 2019-06-05 |
| JP2017155063A (ja) | 2017-09-07 |
| US20240124518A1 (en) | 2024-04-18 |
| CA2737921A1 (en) | 2010-03-25 |
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