JP2012502915A - てんかんを治療する組成物及び方法 - Google Patents
てんかんを治療する組成物及び方法 Download PDFInfo
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- JP2012502915A JP2012502915A JP2011527044A JP2011527044A JP2012502915A JP 2012502915 A JP2012502915 A JP 2012502915A JP 2011527044 A JP2011527044 A JP 2011527044A JP 2011527044 A JP2011527044 A JP 2011527044A JP 2012502915 A JP2012502915 A JP 2012502915A
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- Prior art keywords
- epilepsy
- pharmaceutically acceptable
- therapeutically effective
- focal
- effective amount
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9694008P | 2008-09-15 | 2008-09-15 | |
| US61/096,940 | 2008-09-15 | ||
| US18320909P | 2009-06-02 | 2009-06-02 | |
| US61/183,209 | 2009-06-02 | ||
| PCT/US2009/056988 WO2010031054A1 (en) | 2008-09-15 | 2009-09-15 | Compositions and methods for treating epilepsy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012502915A true JP2012502915A (ja) | 2012-02-02 |
| JP2012502915A5 JP2012502915A5 (enExample) | 2013-05-16 |
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| JP2011527044A Pending JP2012502915A (ja) | 2008-09-15 | 2009-09-15 | てんかんを治療する組成物及び方法 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR101424514B1 (ko) | 2013-01-02 | 2014-07-31 | 건국대학교 산학협력단 | 선천성 발프로산 노출 증후군 치료제로서의 메만틴의 용도 |
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| GB2531282A (en) | 2014-10-14 | 2016-04-20 | Gw Pharma Ltd | Use of cannabinoids in the treatment of epilepsy |
| EP3331511A4 (en) * | 2015-08-03 | 2019-04-03 | B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University | MODULATORS OF HEMATO-ENCEPHALIC BARRIER PERMEABILITY AND USES THEREOF |
| WO2017218344A1 (en) | 2016-06-14 | 2017-12-21 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Methods for treating neurological conditions and exposure to nerve agents |
| CA3045043A1 (en) | 2016-12-31 | 2018-07-05 | Bioxcel Therapeutics, Inc. | Use of sublingual dexmedetomidine for the treatment of agitation |
| CN115154440A (zh) | 2018-06-27 | 2022-10-11 | 比奥克斯塞尔医疗股份有限公司 | 含右美托咪定的膜制剂及其制造方法 |
| WO2021016112A2 (en) | 2019-07-19 | 2021-01-28 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| US20240139169A1 (en) * | 2021-02-26 | 2024-05-02 | Bioxcel Therapeutics, Inc. | Methods and compositions for treating agitation |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101424514B1 (ko) | 2013-01-02 | 2014-07-31 | 건국대학교 산학협력단 | 선천성 발프로산 노출 증후군 치료제로서의 메만틴의 용도 |
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| EP2340254A1 (en) | 2011-07-06 |
| WO2010031054A1 (en) | 2010-03-18 |
| US11389435B2 (en) | 2022-07-19 |
| EP2340254A4 (en) | 2012-04-25 |
| EP2340254B1 (en) | 2014-04-02 |
| EP2340254B8 (en) | 2014-05-21 |
| US20200345710A1 (en) | 2020-11-05 |
| US20150133488A1 (en) | 2015-05-14 |
| US20110172262A1 (en) | 2011-07-14 |
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