JP2012501332A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012501332A5 JP2012501332A5 JP2011525134A JP2011525134A JP2012501332A5 JP 2012501332 A5 JP2012501332 A5 JP 2012501332A5 JP 2011525134 A JP2011525134 A JP 2011525134A JP 2011525134 A JP2011525134 A JP 2011525134A JP 2012501332 A5 JP2012501332 A5 JP 2012501332A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- lyophilized
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9232608P | 2008-08-27 | 2008-08-27 | |
| US61/092,326 | 2008-08-27 | ||
| PCT/US2009/054842 WO2010027766A1 (en) | 2008-08-27 | 2009-08-25 | Lyophilized formulatons of engineered anti-il-23p19 antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015184258A Division JP2016028086A (ja) | 2008-08-27 | 2015-09-17 | 操作された抗ＩＬ−２３ｐ１９抗体の凍結乾燥製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012501332A JP2012501332A (ja) | 2012-01-19 |
| JP2012501332A5 true JP2012501332A5 (https=) | 2012-10-04 |
| JP5931442B2 JP5931442B2 (ja) | 2016-06-08 |
Family
ID=41495339
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011525134A Active JP5931442B2 (ja) | 2008-08-27 | 2009-08-25 | 操作された抗ＩＬ−２３ｐ１９抗体の凍結乾燥製剤 |
| JP2015184258A Pending JP2016028086A (ja) | 2008-08-27 | 2015-09-17 | 操作された抗ＩＬ−２３ｐ１９抗体の凍結乾燥製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015184258A Pending JP2016028086A (ja) | 2008-08-27 | 2015-09-17 | 操作された抗ＩＬ−２３ｐ１９抗体の凍結乾燥製剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8263748B2 (https=) |
| EP (1) | EP2331078B1 (https=) |
| JP (2) | JP5931442B2 (https=) |
| CN (1) | CN102202655B (https=) |
| AU (1) | AU2009288419B2 (https=) |
| CA (1) | CA2734919C (https=) |
| MX (1) | MX2011002159A (https=) |
| WO (1) | WO2010027766A1 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| EP2596022A4 (en) * | 2010-07-20 | 2014-11-05 | Cephalon Australia Pty Ltd | SPECIFIC ANTIBODIES ANTI-HETERODIMER IL-23 |
| PE20141162A1 (es) | 2010-11-04 | 2014-09-18 | Boehringer Ingelheim Int | Anticuerpos anti-il-23 |
| SG10201604104PA (en) | 2011-10-25 | 2016-07-28 | Prothena Therapeutics Ltd | Antibody formulations and methods |
| EP2798077A2 (en) | 2011-12-31 | 2014-11-05 | Allergan, Inc. | Highly Sensitive Cell-Based Assay to Detect the Presence of Active Botulinum Neurotoxin Serotype-A |
| CA2864539C (en) * | 2012-02-16 | 2022-06-07 | Santarus, Inc. | Antibody formulations |
| EP4039275A1 (en) * | 2012-05-03 | 2022-08-10 | Boehringer Ingelheim International GmbH | Anti-il-23p19 antibodies |
| CZ304514B6 (cs) | 2012-11-23 | 2014-06-11 | Biotechnologický Ústav Av Čr, V.V.I. | Polypeptidy pro léčbu autoimunitních chorob založenou na blokaci receptoru pro lidský cytokin IL-23 |
| UA117466C2 (uk) * | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| KR20150128859A (ko) | 2013-03-15 | 2015-11-18 | 암젠 인크 | 항-il23 항체를 사용하여 크론병을 치료하는 방법 |
| EP2968488A1 (en) | 2013-03-15 | 2016-01-20 | Amgen Inc. | Methods for treating psoriasis using an anti-il-23 antibody |
| EP3172339A1 (en) | 2014-07-24 | 2017-05-31 | Boehringer Ingelheim International GmbH | Biomarkers useful in the treatment of il-23a related diseases |
| UA123624C2 (uk) | 2014-09-03 | 2021-05-05 | Бьорінґер Інґельхайм Інтернаціональ Ґмбх | Сполука, специфічна до іл-23а та фнп-альфа, та її застосування |
| AR102417A1 (es) | 2014-11-05 | 2017-03-01 | Lilly Co Eli | Anticuerpos biespecíficos anti-tnf- / anti-il-23 |
| CN107206081A (zh) | 2015-02-04 | 2017-09-26 | 勃林格殷格翰国际有限公司 | 治疗炎性疾病的方法 |
| JP6909208B2 (ja) | 2015-09-17 | 2021-07-28 | アムジェン インコーポレイテッド | Ｉｌ２３経路バイオマーカーを使用するｉｌ２３アンタゴニストに対する臨床応答の予測 |
| JP2018538249A (ja) | 2015-11-04 | 2018-12-27 | アストラゼネカ アクチボラグ | 好酸球性疾患における好酸球標的化治療薬に対する臨床応答の予測変数としてのジペプチジルペプチダーゼ−４およびペリオスチン |
| AU2016379157A1 (en) | 2015-12-22 | 2018-06-21 | Amgen Inc. | CCL20 as a predictor of clinical response to IL23-antagonists |
| HRP20200399T1 (hr) | 2016-01-22 | 2020-06-12 | Baxter International Inc. | Postupak i stroj za proizvodnju vrećica za sterilne otopine |
| PT3405161T (pt) | 2016-01-22 | 2020-01-29 | Baxter Healthcare Sa | Saco de produto para soluções estéreis |
| US10940185B2 (en) | 2016-12-28 | 2021-03-09 | Jcr Pharmaceuticals Co., Ltd. | Lyophilized preparation |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| AU2018263868A1 (en) | 2017-05-02 | 2019-12-12 | Merck Sharp & Dohme Llc | Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies |
| CA3105598A1 (en) | 2018-07-13 | 2020-01-16 | Carl GOMMOLL | Treating ulcerative colitis with brazikumab |
| KR102885113B1 (ko) | 2018-10-18 | 2025-11-13 | 머크 샤프 앤드 돔 엘엘씨 | 항-rsv 항체의 제제 및 그의 사용 방법 |
| CN120842406A (zh) | 2018-10-31 | 2025-10-28 | 默沙东有限责任公司 | 抗人pd-1抗体晶体及其使用方法 |
| CN113316458B (zh) | 2018-11-07 | 2024-08-02 | 默沙东有限责任公司 | 抗lag3抗体和抗pd-1抗体的共制剂 |
| EP3904382A4 (en) | 2018-11-27 | 2022-07-13 | Innovent Biologics (Suzhou) Co., Ltd. | ANTI-IL-23P19 ANTIBODIES AND ITS USES |
| KR102735988B1 (ko) | 2019-02-18 | 2024-12-03 | 일라이 릴리 앤드 캄파니 | 치료 항체 제제 |
| WO2020212874A1 (en) * | 2019-04-15 | 2020-10-22 | Sun Pharma Global Fze | Methods for treatment of subjects with psoriatic arthritis |
| US12577297B2 (en) * | 2019-09-09 | 2026-03-17 | Boehringer Ingelheim International Gmbh | Anti-IL-23p19 antibody formulations |
| GB202107153D0 (en) * | 2021-05-19 | 2021-06-30 | UCB Biopharma SRL | Method for filling vials containing liquid drug products |
| CN115785267B (zh) * | 2021-09-10 | 2023-12-15 | 三优生物医药(上海)有限公司 | 一种靶向IL-23p19的抗体或其抗原结合片段及其应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US6685940B2 (en) | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US6991790B1 (en) | 1997-06-13 | 2006-01-31 | Genentech, Inc. | Antibody formulation |
| US6171586B1 (en) | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| EP2921180B1 (en) | 1999-02-22 | 2019-08-14 | University of Connecticut | Albumin-free factor VIII formulations |
| CA2454587C (en) * | 2001-07-25 | 2012-11-13 | Protein Design Labs, Inc. | Stable lyophilized pharmaceutical formulation of igg antibodies |
| RU2358763C2 (ru) | 2003-02-10 | 2009-06-20 | Элан Фармасьютикалз, Инк. | Композиции иммуноглобулина и способ их получения |
| KR101424624B1 (ko) * | 2003-05-14 | 2014-07-31 | 이뮤노젠 아이엔씨 | 약물 콘쥬게이트 조성물 |
| WO2005035574A1 (ja) * | 2003-10-09 | 2005-04-21 | Chugai Seiyaku Kabushiki Kaisha | IgM高濃度安定化溶液 |
| KR20080019249A (ko) | 2005-06-15 | 2008-03-03 | 쉐링 코포레이션 | 안정한 항체 제형 |
| AU2006265002B2 (en) | 2005-06-30 | 2012-09-20 | Centocor, Inc. | Anti-IL-23 antibodies, compositions, methods and uses |
| DE602006015830D1 (de) | 2005-08-25 | 2010-09-09 | Lilly Co Eli | Anti-il-23-antikörper |
| EP3190125A1 (en) | 2005-08-31 | 2017-07-12 | Merck Sharp & Dohme Corp. | Engineered anti-il-23 antibodies |
| SI1971366T1 (sl) * | 2005-12-29 | 2014-10-30 | Janssen Biotech, Inc. | Humana protitelesa anti-il-23, sestavki, postopki in uporabe |
| CA2644906C (en) * | 2006-03-06 | 2016-05-10 | Medimmune, Inc. | Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
| JP2009540018A (ja) | 2006-06-13 | 2009-11-19 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−１７およびｉｌ−２３アンタゴニストならびにその使用方法 |
| CN104524567A (zh) * | 2007-01-16 | 2015-04-22 | 阿布维公司 | 用于治疗银屑病的方法 |
| EP2426145B1 (en) | 2007-02-23 | 2017-01-18 | Merck Sharp & Dohme Corp. | Engineered anti-il-23p19 antibodies |
| AR065420A1 (es) | 2007-02-23 | 2009-06-03 | Schering Corp | Anticuerpos anti-il-23 p19 de ingenieria |
| AR068723A1 (es) | 2007-10-05 | 2009-12-02 | Glaxo Group Ltd | Proteina que se une a antigenos que se une a il-23 humana y sus usos |
-
2009
- 2009-08-25 CA CA2734919A patent/CA2734919C/en active Active
- 2009-08-25 AU AU2009288419A patent/AU2009288419B2/en active Active
- 2009-08-25 CN CN2009801428023A patent/CN102202655B/zh active Active
- 2009-08-25 EP EP09791868A patent/EP2331078B1/en active Active
- 2009-08-25 US US13/061,076 patent/US8263748B2/en active Active
- 2009-08-25 JP JP2011525134A patent/JP5931442B2/ja active Active
- 2009-08-25 WO PCT/US2009/054842 patent/WO2010027766A1/en not_active Ceased
- 2009-08-25 MX MX2011002159A patent/MX2011002159A/es active IP Right Grant
-
2015
- 2015-09-17 JP JP2015184258A patent/JP2016028086A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012501332A5 (https=) | ||
| JP7528249B2 (ja) | Ｃｏｖｉｄ－１９に対する抗原特異的免疫療法、融合タンパク質、およびその使用方法 | |
| Huleatt et al. | A West Nile virus recombinant protein vaccine that coactivates innate and adaptive immunity | |
| Tai et al. | A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection | |
| Sun et al. | Thermal stability of self-assembled peptide vaccine materials | |
| US9861696B2 (en) | Monoclonal antibodies for Ebola and Marburg viruses | |
| JP5960120B2 (ja) | ウイルス粒子の安定化 | |
| US20230181730A1 (en) | Methods of treating infections | |
| BR112021004193A2 (pt) | vacinas pneumocócicas multivalentes | |
| JP2016534052A5 (https=) | ||
| IL274846B2 (en) | Formulation for anti-alpha 4 antibody in cell 7 | |
| Nguyen et al. | The respiratory syncytial virus G protein conserved domain induces a persistent and protective antibody response in rodents | |
| Stinson et al. | Thin silk fibroin films as a dried format for temperature stabilization of inactivated polio vaccine | |
| US11406704B2 (en) | Adjuvants | |
| BR112014006175B1 (pt) | Anticorpos capazes de neutralisar as exotoxinas principais tcda e tcdb de clostridium difficile | |
| KR20130114210A (ko) | 스타필로코커스 아우레우스 항원의 안정한 면역원성 조성물 | |
| KR102922338B1 (ko) | 폐렴구균 융합 단백질 백신 | |
| JPS58213723A (ja) | 口蹄疫ウイルス抗原の特異性を有する小型ペプチド | |
| CN114729031A (zh) | 抗溶瘤病毒抗原抗体及其使用方法 | |
| Demircan et al. | Biotin functionalized self‐assembled peptide nanofiber as an adjuvant for immunomodulatory response | |
| TWI615158B (zh) | 多肽之調配物 | |
| US20230210980A1 (en) | Chimeric adenoviral vectors | |
| US20230233667A1 (en) | Coronavirus vaccine | |
| Zagorski et al. | Peptide Nanoarray Scaffold Vaccine for SARS-COV-2 and Its Variants of Concerns | |
| US10829542B2 (en) | Methods for affecting Salmonella infections |