JP2012500642A5 - - Google Patents
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- Publication number
- JP2012500642A5 JP2012500642A5 JP2011524360A JP2011524360A JP2012500642A5 JP 2012500642 A5 JP2012500642 A5 JP 2012500642A5 JP 2011524360 A JP2011524360 A JP 2011524360A JP 2011524360 A JP2011524360 A JP 2011524360A JP 2012500642 A5 JP2012500642 A5 JP 2012500642A5
- Authority
- JP
- Japan
- Prior art keywords
- endolysin
- seq
- variant according
- endolysin variant
- peptide stretch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0815484.1 | 2008-08-26 | ||
| GBGB0815484.1A GB0815484D0 (en) | 2008-08-26 | 2008-08-26 | Antibacterial agents |
| PCT/EP2009/060947 WO2010023207A2 (en) | 2008-08-26 | 2009-08-25 | Antimicrobial agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012265070A Division JP5571757B2 (ja) | 2008-08-26 | 2012-12-04 | 抗微生物剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012500642A JP2012500642A (ja) | 2012-01-12 |
| JP2012500642A5 true JP2012500642A5 (cg-RX-API-DMAC10.html) | 2012-07-26 |
| JP5153943B2 JP5153943B2 (ja) | 2013-02-27 |
Family
ID=39846783
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011524360A Active JP5153943B2 (ja) | 2008-08-26 | 2009-08-25 | 抗微生物剤 |
| JP2012265070A Active JP5571757B2 (ja) | 2008-08-26 | 2012-12-04 | 抗微生物剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012265070A Active JP5571757B2 (ja) | 2008-08-26 | 2012-12-04 | 抗微生物剤 |
Country Status (16)
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0815484D0 (en) | 2008-08-26 | 2008-10-01 | Univ Leuven Kath | Antibacterial agents |
| US20120195872A1 (en) * | 2009-06-26 | 2012-08-02 | Lysando Ag | Antimicrobial agents |
| PL2445515T3 (pl) | 2009-06-26 | 2016-10-31 | Środki przeciwdrobnoustrojowe | |
| JP5847081B2 (ja) | 2009-08-24 | 2016-01-20 | カトリック ユニバーシテイト ルーベン ケイ．ユー． ルーベン アール アンド ディー | エンドリシンＯＢＰｇｐＬＹＳ |
| DK2563916T3 (en) * | 2010-04-27 | 2015-10-05 | Lysando Ag | METHOD FOR REDUCING biofilms |
| RU2614114C2 (ru) * | 2010-09-17 | 2017-03-22 | Текнифар-Индустриа Текника Фармасьютика, С.А | Бактериофаги, фаговые пептиды и способы их применения |
| GB201018518D0 (en) * | 2010-11-03 | 2010-12-15 | Univ Leuven Kath | Novel endolysin |
| EP2468856A1 (en) * | 2010-12-23 | 2012-06-27 | Lysando Aktiengesellschaft | Antimicrobial Agents |
| MX383544B (es) * | 2011-04-21 | 2025-03-14 | Univ Rockefeller | Lisinas de bacteriofago de streptococcus para la deteccion y tratamiento de bacterias gram positivas |
| US20140120074A1 (en) * | 2011-04-27 | 2014-05-01 | Lysando Ag | Antimicrobial agents |
| US9068204B2 (en) | 2013-03-15 | 2015-06-30 | The United States Of America, As Represented By The Secretary Of Agriculture | Peptidoglycan hydrolase antimicrobials for eradicating lactobacilli that contaminate and reduce ethanol yields in biofuel fermentation |
| WO2015070912A1 (en) | 2013-11-14 | 2015-05-21 | Lysando Ag | Modified el188 endolysin sequence |
| WO2015070911A1 (en) | 2013-11-14 | 2015-05-21 | Lysando Ag | Modified kz144 endolysin sequence |
| WO2015121443A1 (en) | 2014-02-14 | 2015-08-20 | Lysando Ag | Antimicrobial agents |
| US20170106058A1 (en) * | 2014-04-08 | 2017-04-20 | Lysando Ag | Pharmaceutical composition against chronic bacterial infections |
| BR112016030580B1 (pt) * | 2014-06-26 | 2023-12-19 | The Rockefeller University | Polipeptídeo de lisina e fragmento de polipeptídeo com atividade para matar bactérias gram-negativas |
| CN104762285B (zh) * | 2015-04-23 | 2017-10-27 | 武汉菲吉乐科生物科技有限公司 | 一种自内裂解大肠杆菌的裂解酶及其应用 |
| AU2017375050B2 (en) * | 2016-12-16 | 2021-07-22 | Universidade Do Minho | Novel endolysin |
| KR20240162610A (ko) * | 2017-04-03 | 2024-11-15 | 사시나파스 컴퍼니 리미티드 | 조작된 그람-음성 엔도리신 |
| BR112020011433A2 (pt) * | 2017-12-12 | 2020-12-01 | Contrafect Corporation | identificação de lisinas e seus derivados com atividade bacteriana contra pseudomonas aeruginosa |
| US11958890B2 (en) | 2018-05-30 | 2024-04-16 | Lysando Ag | Antimicrobial proteins |
| US20210198645A1 (en) | 2018-05-30 | 2021-07-01 | Lysando Ag | Novel antimicrobial fusion proteins |
| SG11202111067YA (en) * | 2019-05-08 | 2021-11-29 | Phagomed Biopharma Gmbh | Novel gardnerella endolysins and uses thereof |
| WO2023225518A2 (en) * | 2022-05-16 | 2023-11-23 | The Broad Institute, Inc. | Engineered pnma proteins and delivery systems thereof |
| CN117737001B (zh) * | 2022-12-27 | 2024-08-09 | 菲吉乐科(南京)生物科技有限公司 | 一种防治犬细菌性腹泻的大肠杆菌噬菌体及其应用 |
| CN118620800B (zh) * | 2024-08-08 | 2024-11-12 | 中国兽医药品监察所 | 一株鼻疽伯克霍尔德氏菌及其应用 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3854476T2 (de) | 1987-07-06 | 1996-04-04 | Univ Louisiana State | Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden. |
| GB2255561B (en) | 1991-04-20 | 1995-06-21 | Agricultural & Food Res | Lysins from bacteriophages |
| WO1994004688A2 (en) | 1992-08-21 | 1994-03-03 | The University Of British Columbia | Cationic peptides and method for production |
| ES2154344T3 (es) | 1994-09-01 | 2001-04-01 | Novozymes As | Composicion proteica basica para matar o inhibir celulas microbianas. |
| US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
| US6428784B1 (en) | 1997-10-31 | 2002-08-06 | New Horizons Diagnostics Corp | Vaginal suppository for treating group B Streptococcus infection |
| US5997862A (en) * | 1997-10-31 | 1999-12-07 | New Horizons Diagnostics Corporation | Therapeutic treatment of group A streptococcal infections |
| US6288212B1 (en) | 1998-08-28 | 2001-09-11 | The University Of British Columbia | Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor |
| US5993809A (en) | 1998-11-18 | 1999-11-30 | Children's Hospital Medical Center | Lysozyme fusion proteins in infections |
| AU5553600A (en) | 1999-06-23 | 2001-01-31 | Ppl Therapeutics (Scotland) Ltd | Fusion proteins incorporating lysozyme |
| CA2482995C (en) | 2002-04-22 | 2013-01-29 | Dow Global Technologies Inc. | Low-cost production of peptides |
| US7566447B2 (en) | 2003-05-15 | 2009-07-28 | Iogenetics, Llc | Biocides |
| BRPI0413833A (pt) | 2003-09-11 | 2006-10-24 | Novozymes As | célula hospedeira microbiana recombinante, construção de ácido nucleico, método para produzir uma enzima e/ou um agente antimicrobiano, produto de fusão, aditivo e composição de ração animal, animal não humano transgênico ou produtos ou elementos deste, usos do produto de fusão, da co-expressão de um agente antimicrobiano e uma enzima, e de um peptìdeo de proteção, e, método para identificar um peptìdeo de proteção |
| WO2005108563A2 (en) | 2004-04-19 | 2005-11-17 | University Of Chicago | Peptidoglycan-hydrolyzing protein encoded by bacteriophage n4 |
| US7572602B1 (en) | 2004-12-03 | 2009-08-11 | The United States Of America As Represented By The Secretary Of Agriculture | Nucleic acid encoding endolysin fusion protein |
| DE102005040347A1 (de) | 2005-08-25 | 2007-03-01 | Profos Ag | Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von Listerien |
| WO2007113499A1 (en) | 2006-03-31 | 2007-10-11 | The University Court Of The University Of St Andrews | Anti-microbial compositions comprising a cationic peptide and a glycylglycine endopeptidase |
| DE102006061002A1 (de) | 2006-12-22 | 2008-06-26 | Profos Ag | Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von gram-positiven Bakterien |
| CN107129524B (zh) | 2007-09-25 | 2023-11-21 | 田园温室气体研究有限公司 | 用于抑制微生物细胞的疫苗和疫苗组分 |
| EP2225263A1 (en) | 2007-11-26 | 2010-09-08 | Plant Bioscience Limited | Novel polypeptides having endolysin activity and uses thereof |
| WO2010011960A2 (en) | 2008-07-24 | 2010-01-28 | The United State Of America, As Represented By The Secretary Of Agriculture | Triple acting antimicrobials that are refractory to resistance development |
| EP2157100A1 (en) | 2008-08-19 | 2010-02-24 | Profos AG | Artificial peptidoglycan lysing enzymes and peptidoglycan binding proteins |
| GB0815484D0 (en) | 2008-08-26 | 2008-10-01 | Univ Leuven Kath | Antibacterial agents |
| US8389679B2 (en) | 2009-02-05 | 2013-03-05 | The Regents Of The University Of California | Targeted antimicrobial moieties |
| PL2445515T3 (pl) | 2009-06-26 | 2016-10-31 | Środki przeciwdrobnoustrojowe | |
| JP5847081B2 (ja) | 2009-08-24 | 2016-01-20 | カトリック ユニバーシテイト ルーベン ケイ．ユー． ルーベン アール アンド ディー | エンドリシンＯＢＰｇｐＬＹＳ |
| DK2563916T3 (en) | 2010-04-27 | 2015-10-05 | Lysando Ag | METHOD FOR REDUCING biofilms |
-
2008
- 2008-08-26 GB GBGB0815484.1A patent/GB0815484D0/en not_active Ceased
-
2009
- 2009-08-25 BR BRPI0917508-3A patent/BRPI0917508A2/pt not_active Application Discontinuation
- 2009-08-25 MX MX2011001957A patent/MX2011001957A/es active IP Right Grant
- 2009-08-25 KR KR1020117006983A patent/KR101473271B1/ko active Active
- 2009-08-25 CN CN200980142373.XA patent/CN102197132B/zh active Active
- 2009-08-25 JP JP2011524360A patent/JP5153943B2/ja active Active
- 2009-08-25 ES ES09782176T patent/ES2395357T3/es active Active
- 2009-08-25 EA EA201100312A patent/EA024794B1/ru not_active IP Right Cessation
- 2009-08-25 WO PCT/EP2009/060947 patent/WO2010023207A2/en not_active Ceased
- 2009-08-25 EP EP09782176A patent/EP2331687B1/en active Active
- 2009-08-25 CA CA2735077A patent/CA2735077C/en active Active
- 2009-08-25 DK DK09782176.3T patent/DK2331687T3/da active
- 2009-08-25 AU AU2009286760A patent/AU2009286760B2/en not_active Ceased
- 2009-08-25 PL PL09782176T patent/PL2331687T3/pl unknown
- 2009-08-25 US US13/061,053 patent/US9809808B2/en not_active Expired - Fee Related
-
2011
- 2011-02-27 IL IL211441A patent/IL211441A/en active IP Right Grant
-
2012
- 2012-12-04 JP JP2012265070A patent/JP5571757B2/ja active Active
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