JP2012500286A5 - - Google Patents
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- JP2012500286A5 JP2012500286A5 JP2011523987A JP2011523987A JP2012500286A5 JP 2012500286 A5 JP2012500286 A5 JP 2012500286A5 JP 2011523987 A JP2011523987 A JP 2011523987A JP 2011523987 A JP2011523987 A JP 2011523987A JP 2012500286 A5 JP2012500286 A5 JP 2012500286A5
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- Japan
- Prior art keywords
- antigen
- cancer
- moiety
- antibody
- dnl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9048708P | 2008-08-20 | 2008-08-20 | |
| US61/090,487 | 2008-08-20 | ||
| PCT/US2009/054441 WO2010022225A1 (en) | 2008-08-20 | 2009-08-20 | Dock-and-lock (dnl) vaccines for cancer therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012500286A JP2012500286A (ja) | 2012-01-05 |
| JP2012500286A5 true JP2012500286A5 (https=) | 2012-09-20 |
| JP5870404B2 JP5870404B2 (ja) | 2016-03-01 |
Family
ID=41707458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523987A Active JP5870404B2 (ja) | 2008-08-20 | 2009-08-20 | 癌治療のためのドック・ロック（ｄｎｌ）ワクチン |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7901680B2 (https=) |
| EP (1) | EP2326346A4 (https=) |
| JP (1) | JP5870404B2 (https=) |
| CN (1) | CN102186499B (https=) |
| AU (1) | AU2009282830B2 (https=) |
| CA (1) | CA2734265C (https=) |
| WO (1) | WO2010022225A1 (https=) |
Families Citing this family (68)
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| US7312318B2 (en) * | 2002-03-01 | 2007-12-25 | Immunomedics, Inc. | Internalizing anti-CD74 antibodies and methods of use |
| US7666400B2 (en) | 2005-04-06 | 2010-02-23 | Ibc Pharmaceuticals, Inc. | PEGylation by the dock and lock (DNL) technique |
| US20160279239A1 (en) | 2011-05-02 | 2016-09-29 | Immunomedics, Inc. | Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease |
| US8658773B2 (en) | 2011-05-02 | 2014-02-25 | Immunomedics, Inc. | Ultrafiltration concentration of allotype selected antibodies for small-volume administration |
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| US9550838B2 (en) | 2004-02-13 | 2017-01-24 | Ibc Pharmaceuticals, Inc. | Dock-and-lock (DNL) complexes for therapeutic and diagnostic use |
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| US8475794B2 (en) | 2005-04-06 | 2013-07-02 | Ibc Pharmaceuticals, Inc. | Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases |
| US8349332B2 (en) | 2005-04-06 | 2013-01-08 | Ibc Pharmaceuticals, Inc. | Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases |
| US9931413B2 (en) | 2005-04-06 | 2018-04-03 | Ibc Pharmaceuticals, Inc. | Tetrameric cytokines with improved biological activity |
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| US9623115B2 (en) | 2005-04-06 | 2017-04-18 | Ibc Pharmaceuticals, Inc. | Dock-and-Lock (DNL) Complexes for Disease Therapy |
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| US9862770B2 (en) | 2005-10-19 | 2018-01-09 | Ibc Pharmaceuticals, Inc. | Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors |
| WO2012024223A2 (en) * | 2010-08-17 | 2012-02-23 | Immunomedics, Inc. | Combination therapy with anti-cd74 antibodies provides enhanced toxicity to malignancies, autoimmune disease and other diseases |
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| CN102186499B (zh) * | 2008-08-20 | 2015-05-20 | Ibc医药公司 | 用于癌症治疗的对接和锁定(dnl)疫苗 |
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| US10131712B2 (en) | 2012-08-14 | 2018-11-20 | Ibc Pharmaceuticals, Inc. | Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors |
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| JP6447933B2 (ja) | 2014-02-21 | 2019-01-09 | アイビーシー ファーマスーティカルズ，インコーポレイテッド | Ｔｒｏｐ−２発現細胞に対する免疫応答を誘発することによる疾患治療 |
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| EP3262070A4 (en) | 2015-02-24 | 2018-07-25 | Rpeptide, LLC | Anti-amyloid-beta antibodies |
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| JP6980980B2 (ja) | 2015-06-25 | 2021-12-15 | イミューノメディクス、インコーポレイテッドImmunomedics, Inc. | 抗ｈｌａ‐ｄｒまたは抗ｔｒｏｐ‐２抗体と微小管阻害剤、ｐａｒｐ阻害剤、ブルトンキナーゼ阻害剤またはホスホイノシチド３‐キナーゼ阻害剤との併用は癌の治療効果を有意に改善する |
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| US10669338B2 (en) | 2016-06-17 | 2020-06-02 | Immunomedics, Inc. | Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1 |
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| CN108379567A (zh) * | 2018-02-28 | 2018-08-10 | 宁夏医科大学 | 抗黑色素瘤纳米颗粒疫苗及其制备与应用 |
| WO2020172233A1 (en) * | 2019-02-22 | 2020-08-27 | The Trustees Of Columbia University In The City Of New York | Treatment of prostate cancer by androgen ablation and il-8 blockade |
| WO2023056240A2 (en) | 2021-09-28 | 2023-04-06 | Frontaim Biomedicines, Inc. | Multiple formats of molecular complexes |
| CN119816521A (zh) * | 2022-09-23 | 2025-04-11 | 准星生物医药有限公司 | 具有多种功能或结合特异性的分子嫁接免疫球蛋白 |
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2009
- 2009-08-20 CN CN200980141590.7A patent/CN102186499B/zh active Active
- 2009-08-20 AU AU2009282830A patent/AU2009282830B2/en active Active
- 2009-08-20 US US12/544,476 patent/US7901680B2/en not_active Expired - Lifetime
- 2009-08-20 JP JP2011523987A patent/JP5870404B2/ja active Active
- 2009-08-20 WO PCT/US2009/054441 patent/WO2010022225A1/en not_active Ceased
- 2009-08-20 EP EP09808814A patent/EP2326346A4/en not_active Withdrawn
- 2009-08-20 CA CA2734265A patent/CA2734265C/en active Active
-
2011
- 2011-01-21 US US13/010,993 patent/US9457072B2/en active Active
-
2016
- 2016-08-24 US US15/246,089 patent/US20160361405A1/en not_active Abandoned
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