JP2012180344A5 - - Google Patents
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- JP2012180344A5 JP2012180344A5 JP2012023811A JP2012023811A JP2012180344A5 JP 2012180344 A5 JP2012180344 A5 JP 2012180344A5 JP 2012023811 A JP2012023811 A JP 2012023811A JP 2012023811 A JP2012023811 A JP 2012023811A JP 2012180344 A5 JP2012180344 A5 JP 2012180344A5
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- JP
- Japan
- Prior art keywords
- alkyl
- membered
- haloalkyl
- membered heterocyclyl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012023811A JP5620417B2 (ja) | 2011-02-07 | 2012-02-07 | アミノピラゾール誘導体を含む医薬 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011024078 | 2011-02-07 | ||
| JP2011024078 | 2011-02-07 | ||
| JP2012023811A JP5620417B2 (ja) | 2011-02-07 | 2012-02-07 | アミノピラゾール誘導体を含む医薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012180344A JP2012180344A (ja) | 2012-09-20 |
| JP2012180344A5 true JP2012180344A5 (enExample) | 2014-10-02 |
| JP5620417B2 JP5620417B2 (ja) | 2014-11-05 |
Family
ID=47011846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012023811A Expired - Fee Related JP5620417B2 (ja) | 2011-02-07 | 2012-02-07 | アミノピラゾール誘導体を含む医薬 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5620417B2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3015953B1 (ja) | 1998-10-06 | 2000-03-06 | 株式会社ワールド・ブリック | れんが壁 |
| US10689705B2 (en) * | 2012-09-27 | 2020-06-23 | Chugai Seiyaku Kabushiki Kaisha | FGFR3 fusion gene and pharmaceutical drug targeting same |
| CN103224479B (zh) * | 2013-04-26 | 2014-10-15 | 温州大学 | 一种2-芳基苯并呋喃类化合物的合成方法 |
| CN105636587B (zh) * | 2013-07-31 | 2018-05-18 | 中外制药株式会社 | 含有氨基吡唑衍生物的药物制剂 |
| AU2014338549B2 (en) * | 2013-10-25 | 2017-05-25 | Novartis Ag | Ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors |
| WO2015086636A1 (en) * | 2013-12-13 | 2015-06-18 | F. Hoffmann-La Roche Ag | Inhibitors of bruton's tyrosine kinase |
| MX374758B (es) | 2013-12-13 | 2025-03-06 | Hoffmann La Roche | Inhibidores de tirosina cinasa de bruton. |
| WO2015099127A1 (ja) * | 2013-12-27 | 2015-07-02 | 中外製薬株式会社 | Ｆｇｆｒゲートキーパー変異遺伝子およびそれを標的とする医薬 |
| CN106459993A (zh) * | 2014-03-31 | 2017-02-22 | 德彪药业国际股份公司 | Fgfr融合体 |
| EP3200786B1 (en) * | 2014-10-03 | 2019-08-28 | Novartis AG | Use of ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors |
| US9802917B2 (en) * | 2015-03-25 | 2017-10-31 | Novartis Ag | Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide |
| WO2016204261A1 (ja) * | 2015-06-17 | 2016-12-22 | 中外製薬株式会社 | アミノピラゾール誘導体 |
| JP6549311B2 (ja) | 2015-08-20 | 2019-07-24 | 浙江海正薬業股▲ふん▼有限公司Ｚｈｅｊｉａｎｇ Ｈｉｓｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ ＣＯ．，ＬＴＤ． | インドール誘導体、その調製方法および医薬におけるその使用 |
| CN110950848B (zh) * | 2018-09-27 | 2024-03-26 | 徐诺药业 | 新型氨基吡唑类衍生物的合成与应用 |
| CN113490666A (zh) | 2018-12-19 | 2021-10-08 | 奥瑞生物药品公司 | 作为fgfr酪氨酸激酶的抑制剂的取代的吡唑并[1,5-a]吡啶化合物 |
| EP3898615A1 (en) | 2018-12-19 | 2021-10-27 | Array Biopharma, Inc. | 7-((3,5-dimethoxyphenyl)amino)quinoxaline derivatives as fgfr inhibitors for treating cancer |
| CN112358435B (zh) * | 2019-10-12 | 2023-01-10 | 中国医学科学院医药生物技术研究所 | 取代芳并杂环类化合物、制备方法和抑制ulk1及抗肿瘤用途 |
| US20250122189A1 (en) * | 2021-12-13 | 2025-04-17 | Abbisko Therapeutics Co., Ltd. | Fgfr4 inhibitor acid salt, preparation method therefor and use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6316466B1 (en) * | 1998-05-05 | 2001-11-13 | Syntex (U.S.A.) Llc | Pyrazole derivatives P-38 MAP kinase inhibitors |
| KR100404256B1 (ko) * | 1998-05-05 | 2003-11-01 | 에프. 호프만-라 로슈 아게 | 피-38 엠에이피 키나제 저해제로서의 피라졸 유도체 |
| CN1832928B (zh) * | 2003-06-26 | 2012-07-04 | 诺瓦提斯公司 | 以5元杂环为基础的p38激酶抑制剂 |
| JP2011528686A (ja) * | 2008-07-23 | 2011-11-24 | エフ．ホフマン−ラ ロシュ アーゲー | ヘテロ環式抗ウイルス性化合物 |
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2012
- 2012-02-07 JP JP2012023811A patent/JP5620417B2/ja not_active Expired - Fee Related