JP5620417B2 - アミノピラゾール誘導体を含む医薬 - Google Patents

アミノピラゾール誘導体を含む医薬 Download PDF

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Publication number
JP5620417B2
JP5620417B2 JP2012023811A JP2012023811A JP5620417B2 JP 5620417 B2 JP5620417 B2 JP 5620417B2 JP 2012023811 A JP2012023811 A JP 2012023811A JP 2012023811 A JP2012023811 A JP 2012023811A JP 5620417 B2 JP5620417 B2 JP 5620417B2
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JP
Japan
Prior art keywords
alkyl
amino
methyl
benzimidazol
pyrazol
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Expired - Fee Related
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JP2012023811A
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English (en)
Japanese (ja)
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JP2012180344A5 (enExample
JP2012180344A (ja
Inventor
高　直樹
直樹 高
正幸 大森
正幸 大森
京子 高見
京子 高見
松下正行
正行 松下
忠克 早瀬
忠克 早瀬
郁美 兵藤
郁美 兵藤
雅美 河内
雅美 河内
広樹 西井
広樹 西井
啓達 海老池
啓達 海老池
中西　義人
義人 中西
俊之 三尾
俊之 三尾
リーシャ ワン
リーシャ ワン
ウェイリィ チャオ
ウェイリィ チャオ
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Priority to JP2012023811A priority Critical patent/JP5620417B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Health & Medical Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
JP2012023811A 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬 Expired - Fee Related JP5620417B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012023811A JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011024078 2011-02-07
JP2011024078 2011-02-07
JP2012023811A JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Publications (3)

Publication Number Publication Date
JP2012180344A JP2012180344A (ja) 2012-09-20
JP2012180344A5 JP2012180344A5 (enExample) 2014-10-02
JP5620417B2 true JP5620417B2 (ja) 2014-11-05

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JP2012023811A Expired - Fee Related JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

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JP (1) JP5620417B2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3015953B1 (ja) 1998-10-06 2000-03-06 株式会社ワールド・ブリック れんが壁

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201502455TA (en) * 2012-09-27 2015-05-28 Chugai Pharmaceutical Co Ltd Fgfr3 fusion gene and pharmaceutical drug targeting same
CN103224479B (zh) * 2013-04-26 2014-10-15 温州大学 一种2-芳基苯并呋喃类化合物的合成方法
MX362994B (es) 2013-07-31 2019-03-01 Chugai Pharmaceutical Co Ltd Preparacion farmaceutica que comprende un derivado de aminopirazol.
PE20160546A1 (es) 2013-10-25 2016-05-26 Novartis Ag Compuestos derivados de piridilo biciclicos fusionados a anillo como inhibidores de fgfr4
RU2653500C2 (ru) 2013-12-13 2018-05-10 Ф. Хоффманн-Ля Рош Аг Ингибиторы тирозинкиназы брутона
EP3080099B1 (en) 2013-12-13 2018-04-11 F.Hoffmann-La Roche Ag Inhibitors of bruton's tyrosine kinase
ES2756175T3 (es) * 2013-12-27 2020-04-27 Chugai Pharmaceutical Co Ltd Genes mutantes guardián de fgfr y fármacos que se dirigen a los mismos
KR20160138494A (ko) * 2014-03-31 2016-12-05 데비오팜 인터네셔날 에스 에이 Fgfr 융합물
JP6585167B2 (ja) * 2014-10-03 2019-10-02 ノバルティス アーゲー Ｆｇｆｒ４阻害剤としての縮環二環式ピリジル誘導体の使用
US9802917B2 (en) * 2015-03-25 2017-10-31 Novartis Ag Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
US10479780B2 (en) 2015-06-17 2019-11-19 Chugai Seiyaku Kabushiki Kaisha Aminopyrazole derivatives
WO2017028816A1 (zh) * 2015-08-20 2017-02-23 浙江海正药业股份有限公司 吲哚类衍生物及其制备方法和其在医药上的用途
CN110950848B (zh) * 2018-09-27 2024-03-26 徐诺药业 新型氨基吡唑类衍生物的合成与应用
JP2022515198A (ja) * 2018-12-19 2022-02-17 アレイ バイオファーマ インコーポレイテッド ＦＧＦＲチロシンキナーゼの阻害剤としての置換ピラゾロ［１，５－ａ］ピリジン化合物
CN113474337A (zh) 2018-12-19 2021-10-01 奥瑞生物药品公司 作为fgfr抑制剂用于治疗癌症的7-((3，5-二甲氧基苯基)氨基)喹喔啉衍生物
CN112358435B (zh) * 2019-10-12 2023-01-10 中国医学科学院医药生物技术研究所 取代芳并杂环类化合物、制备方法和抑制ulk1及抗肿瘤用途
US20250122189A1 (en) * 2021-12-13 2025-04-17 Abbisko Therapeutics Co., Ltd. Fgfr4 inhibitor acid salt, preparation method therefor and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316466B1 (en) * 1998-05-05 2001-11-13 Syntex (U.S.A.) Llc Pyrazole derivatives P-38 MAP kinase inhibitors
CN1147476C (zh) * 1998-05-05 2004-04-28 霍夫曼-拉罗奇有限公司 作为p-38map激酶抑制剂的吡唑衍生物
HRP20110757T1 (hr) * 2003-06-26 2011-11-30 Novartis Ag Inhibitori kinaze p38 bazirani na 5-članom heterociklu
WO2010010017A1 (en) * 2008-07-23 2010-01-28 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3015953B1 (ja) 1998-10-06 2000-03-06 株式会社ワールド・ブリック れんが壁

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