JP5620417B2 - アミノピラゾール誘導体を含む医薬 - Google Patents

アミノピラゾール誘導体を含む医薬 Download PDF

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Publication number
JP5620417B2
JP5620417B2 JP2012023811A JP2012023811A JP5620417B2 JP 5620417 B2 JP5620417 B2 JP 5620417B2 JP 2012023811 A JP2012023811 A JP 2012023811A JP 2012023811 A JP2012023811 A JP 2012023811A JP 5620417 B2 JP5620417 B2 JP 5620417B2
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Japan
Prior art keywords
alkyl
amino
methyl
benzimidazol
pyrazol
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Expired - Fee Related
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JP2012023811A
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English (en)
Japanese (ja)
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JP2012180344A5 (enExample
JP2012180344A (ja
Inventor
高　直樹
直樹 高
正幸 大森
正幸 大森
京子 高見
京子 高見
松下正行
正行 松下
忠克 早瀬
忠克 早瀬
郁美 兵藤
郁美 兵藤
雅美 河内
雅美 河内
広樹 西井
広樹 西井
啓達 海老池
啓達 海老池
中西　義人
義人 中西
俊之 三尾
俊之 三尾
リーシャ ワン
リーシャ ワン
ウェイリィ チャオ
ウェイリィ チャオ
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Priority to JP2012023811A priority Critical patent/JP5620417B2/ja
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Publication of JP2012180344A5 publication Critical patent/JP2012180344A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Health & Medical Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
JP2012023811A 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬 Expired - Fee Related JP5620417B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012023811A JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011024078 2011-02-07
JP2011024078 2011-02-07
JP2012023811A JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Publications (3)

Publication Number Publication Date
JP2012180344A JP2012180344A (ja) 2012-09-20
JP2012180344A5 JP2012180344A5 (enExample) 2014-10-02
JP5620417B2 true JP5620417B2 (ja) 2014-11-05

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JP2012023811A Expired - Fee Related JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

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JP (1) JP5620417B2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3015953B1 (ja) 1998-10-06 2000-03-06 株式会社ワールド・ブリック れんが壁

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2886002C (en) 2012-09-27 2020-06-09 Chugai Seiyaku Kabushiki Kaisha Fgfr3 fusion gene and pharmaceutical drug targeting same
CN103224479B (zh) * 2013-04-26 2014-10-15 温州大学 一种2-芳基苯并呋喃类化合物的合成方法
WO2015016295A1 (ja) * 2013-07-31 2015-02-05 中外製薬株式会社 アミノピラゾール誘導体含有医薬品製剤
TR201810944T4 (tr) * 2013-10-25 2018-08-27 Novartis Ag Fgfr4 inhibitörleri olarak halka-füzyonlu bisiklik piridil türevleri.
JP6294490B2 (ja) * 2013-12-13 2018-03-14 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ブルトン型チロシンキナーゼの阻害剤
KR101768402B1 (ko) 2013-12-13 2017-08-14 에프. 호프만-라 로슈 아게 브루톤 티로신 키나제의 억제제
WO2015099127A1 (ja) * 2013-12-27 2015-07-02 中外製薬株式会社 Ｆｇｆｒゲートキーパー変異遺伝子およびそれを標的とする医薬
CA2943405A1 (en) 2014-03-31 2015-10-08 Debiopharm International Sa Fgfr fusions
JP6585167B2 (ja) * 2014-10-03 2019-10-02 ノバルティス アーゲー Ｆｇｆｒ４阻害剤としての縮環二環式ピリジル誘導体の使用
US9802917B2 (en) * 2015-03-25 2017-10-31 Novartis Ag Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
US10479780B2 (en) 2015-06-17 2019-11-19 Chugai Seiyaku Kabushiki Kaisha Aminopyrazole derivatives
EP3339305B1 (en) 2015-08-20 2022-05-04 Zhejiang Hisun Pharmaceutical Co., Ltd Indole derivative, preparation method thereof, and use thereof in pharmaceutical drug
CN110950848B (zh) * 2018-09-27 2024-03-26 徐诺药业 新型氨基吡唑类衍生物的合成与应用
EP3898615A1 (en) 2018-12-19 2021-10-27 Array Biopharma, Inc. 7-((3,5-dimethoxyphenyl)amino)quinoxaline derivatives as fgfr inhibitors for treating cancer
EP3898626A1 (en) 2018-12-19 2021-10-27 Array Biopharma, Inc. Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases
CN112358435B (zh) * 2019-10-12 2023-01-10 中国医学科学院医药生物技术研究所 取代芳并杂环类化合物、制备方法和抑制ulk1及抗肿瘤用途
WO2023109776A1 (zh) * 2021-12-13 2023-06-22 上海和誉生物医药科技有限公司 一种fgfr4抑制剂酸式盐及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316466B1 (en) * 1998-05-05 2001-11-13 Syntex (U.S.A.) Llc Pyrazole derivatives P-38 MAP kinase inhibitors
RU2000130199A (ru) * 1998-05-05 2002-11-10 Ф.Хоффманн-Ля Рош Аг (Ch) Производные пиразола в качестве ингибиторов р-38 мар киназы
CA2526455C (en) * 2003-06-26 2012-10-09 Novartis Ag 5-membered heterocycle-based p38 kinase inhibitors
BRPI0916233A2 (pt) * 2008-07-23 2018-03-13 F.Hoffman-La Roche Ag compostos heterocíclicos antivirais

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3015953B1 (ja) 1998-10-06 2000-03-06 株式会社ワールド・ブリック れんが壁

Also Published As

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