JP2012041355A5 - - Google Patents
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- Publication number
- JP2012041355A5 JP2012041355A5 JP2011225680A JP2011225680A JP2012041355A5 JP 2012041355 A5 JP2012041355 A5 JP 2012041355A5 JP 2011225680 A JP2011225680 A JP 2011225680A JP 2011225680 A JP2011225680 A JP 2011225680A JP 2012041355 A5 JP2012041355 A5 JP 2012041355A5
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- antigen
- transcutaneous immunization
- immunization according
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002649 immunization Methods 0.000 claims 10
- 230000003053 immunization Effects 0.000 claims 10
- 239000000427 antigen Substances 0.000 claims 7
- 108091007433 antigens Proteins 0.000 claims 6
- 102000036639 antigens Human genes 0.000 claims 6
- 239000002671 adjuvant Substances 0.000 claims 4
- OTLLEIBWKHEHGU-UHFFFAOYSA-N 2-[5-[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-4-phosphonooxyhexanedioic acid Chemical compound C1=NC=2C(N)=NC=NC=2N1C(C(C1O)O)OC1COC1C(CO)OC(OC(C(O)C(OP(O)(O)=O)C(O)C(O)=O)C(O)=O)C(O)C1O OTLLEIBWKHEHGU-UHFFFAOYSA-N 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 231100000776 exotoxin Toxicity 0.000 claims 3
- 239000002095 exotoxin Substances 0.000 claims 3
- 239000003961 penetration enhancing agent Substances 0.000 claims 2
- 210000003491 skin Anatomy 0.000 claims 2
- 210000000434 stratum corneum Anatomy 0.000 claims 2
- 239000003053 toxin Substances 0.000 claims 2
- 231100000765 toxin Toxicity 0.000 claims 2
- 108700012359 toxins Proteins 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 108020000946 Bacterial DNA Proteins 0.000 claims 1
- 102000019034 Chemokines Human genes 0.000 claims 1
- 108010012236 Chemokines Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 102000011782 Keratins Human genes 0.000 claims 1
- 108010076876 Keratins Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 239000002390 adhesive tape Substances 0.000 claims 1
- 239000013566 allergen Substances 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 230000000593 degrading effect Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229910001651 emery Inorganic materials 0.000 claims 1
- 239000002158 endotoxin Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000036039 immunity Effects 0.000 claims 1
- 229920006008 lipopolysaccharide Polymers 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 244000045947 parasite Species 0.000 claims 1
- 244000052769 pathogen Species 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 238000005498 polishing Methods 0.000 claims 1
- 229960001005 tuberculin Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7585698P | 1998-02-25 | 1998-02-25 | |
| US7585098P | 1998-02-25 | 1998-02-25 | |
| US60/075,856 | 1998-02-25 | ||
| US60/075,850 | 1998-02-25 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000533145A Division JP4875799B2 (ja) | 1998-02-25 | 1999-02-25 | Ａｄｐ−リボシル化外毒素により誘引される経皮免疫応答を促進するための皮膚浸透性エンハンサーおよびバリア崩壊剤の使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012041355A JP2012041355A (ja) | 2012-03-01 |
| JP2012041355A5 true JP2012041355A5 (https=) | 2012-12-20 |
Family
ID=26757358
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000533145A Expired - Fee Related JP4875799B2 (ja) | 1998-02-25 | 1999-02-25 | Ａｄｐ−リボシル化外毒素により誘引される経皮免疫応答を促進するための皮膚浸透性エンハンサーおよびバリア崩壊剤の使用 |
| JP2011225680A Pending JP2012041355A (ja) | 1998-02-25 | 2011-10-13 | Ａｄｐ−リボシル化外毒素により誘引される経皮免疫応答を促進するための皮膚浸透性エンハンサーおよびバリア崩壊剤の使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000533145A Expired - Fee Related JP4875799B2 (ja) | 1998-02-25 | 1999-02-25 | Ａｄｐ−リボシル化外毒素により誘引される経皮免疫応答を促進するための皮膚浸透性エンハンサーおよびバリア崩壊剤の使用 |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1061951B1 (https=) |
| JP (2) | JP4875799B2 (https=) |
| AT (2) | ATE365050T1 (https=) |
| AU (1) | AU3311599A (https=) |
| BR (1) | BR9908278A (https=) |
| CA (1) | CA2321596C (https=) |
| DE (2) | DE69936355T2 (https=) |
| ES (1) | ES2289200T3 (https=) |
| WO (1) | WO1999043350A1 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6797276B1 (en) | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| EP1486215A3 (en) * | 1997-03-21 | 2006-04-12 | Chiron Corporation | Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants |
| WO2000061184A2 (en) * | 1999-04-08 | 2000-10-19 | Glenn Gregory M | Dry formulation for transcutaneous immunization |
| US20030078499A1 (en) | 1999-08-12 | 2003-04-24 | Eppstein Jonathan A. | Microporation of tissue for delivery of bioactive agents |
| US6835184B1 (en) | 1999-09-24 | 2004-12-28 | Becton, Dickinson And Company | Method and device for abrading skin |
| US8465468B1 (en) | 2000-06-29 | 2013-06-18 | Becton, Dickinson And Company | Intradermal delivery of substances |
| US7030228B1 (en) | 1999-11-15 | 2006-04-18 | Miltenyi Biotec Gmbh | Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby |
| US6595947B1 (en) | 2000-05-22 | 2003-07-22 | Becton, Dickinson And Company | Topical delivery of vaccines |
| GB0017999D0 (en) | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| ES2310201T3 (es) | 2001-02-13 | 2009-01-01 | Government Of The United States Of America, As Represented By The Secretary Of The Army | Vacuna para inmunizacion transcutanea contra la diarrea de los viajeros. |
| JP2004529906A (ja) | 2001-03-19 | 2004-09-30 | イオマイ コーポレイシヨン | 経皮的免疫賦活 |
| CN1516595A (zh) * | 2001-03-19 | 2004-07-28 | Iomai公司 | 用于经皮免疫的贴剂 |
| DK1450855T3 (da) * | 2001-05-23 | 2010-01-11 | Duotol Ab | Undertrykkelse af allergiske reaktioner ved hjælp af transdermal indgivelse af allergener i forbindelse med eller konjugeret til toxin-underenheder eller fragmenter deraf |
| DE60213976T2 (de) | 2001-06-08 | 2007-04-26 | Becton Dickinson And Co. | Vorrichtung zur manipulation von nadeln oder polierarray |
| WO2003002069A2 (en) | 2001-06-29 | 2003-01-09 | Becton, Dickinson And Company | Intradermal delivery of vaccines and gene therapeutic agents via microcannula |
| AU2002367977B2 (en) | 2001-08-13 | 2008-06-19 | University Of Rochester | Transcutaneous immunization against papillomavirus with papillomavirus virus-like particles |
| AU2002365077A1 (en) * | 2001-09-19 | 2003-06-30 | Massachusetts Institute Of Technology | Methods and products related to non-viral transfection |
| US9918665B2 (en) | 2002-03-11 | 2018-03-20 | Nitto Denko Corporation | Transdermal porator and patch system and method for using same |
| CA2478822C (en) | 2002-03-11 | 2016-07-12 | Passport Technologies, Inc. | Transdermal drug delivery patch system, method of making same and method of using same |
| WO2003094995A1 (en) | 2002-05-06 | 2003-11-20 | Becton, Dickinson And Company | Method and device for controlling drug pharmacokinetics |
| US20040009180A1 (en) * | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
| AU2003269839B2 (en) * | 2002-10-02 | 2006-07-27 | Nordic Vaccine A/S | Composition for vaccination |
| EP1590432A4 (en) | 2003-01-15 | 2008-05-14 | Res Inst For Genetic And Human | DNA COMPOSITION AND ITS USE |
| US8016811B2 (en) | 2003-10-24 | 2011-09-13 | Altea Therapeutics Corporation | Method for transdermal delivery of permeant substances |
| US20060002960A1 (en) * | 2003-12-09 | 2006-01-05 | Paul Zoeteweij | GM1 binding deficient exotoxins for use as immunoadjuvants |
| CA2558676C (en) | 2004-03-03 | 2019-04-16 | Essentia Biosystems, Inc. | Compositions and methods for topical diagnostic and therapeutic transport |
| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| SG160357A1 (en) | 2005-03-03 | 2010-04-29 | Revance Therapeutics Inc | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| CA2620943A1 (en) | 2005-09-02 | 2007-03-08 | Iomai Corporation | Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof |
| JP5186678B2 (ja) * | 2005-10-13 | 2013-04-17 | 財団法人ヒューマンサイエンス振興財団 | 経皮抗原投与のための抗原キット |
| CA2626253A1 (en) | 2005-10-18 | 2007-04-26 | Novartis Vaccines And Diagnostics, Inc. | Mucosal and systemic immunizations with alphavirus replicon particles |
| FR2924349B1 (fr) | 2007-12-03 | 2010-01-01 | Dbv Tech | Methode de desensibilitation aux allergenes |
| WO2010013350A1 (ja) | 2008-08-01 | 2010-02-04 | Ａｓｐｉｏｎ株式会社 | Ｓ／ｏ型経皮免疫剤 |
| DE102011018499A1 (de) | 2011-04-23 | 2012-10-25 | Emc Microcollections Gmbh | Topische Nanopartikel-Vakzine zur Immunstimulation der dendritischen Zellen in der Haut |
| WO2014044690A1 (en) | 2012-09-18 | 2014-03-27 | Valneva Austria Gmbh | Improved vaccines |
| JP6577795B2 (ja) * | 2014-09-03 | 2019-09-18 | 日東電工株式会社 | ビスホスホネート剤を含む細胞性免疫用ワクチン医薬組成物 |
| KR20220147278A (ko) | 2021-04-27 | 2022-11-03 | (주)아모레퍼시픽 | 리포푸신 축적 억제 또는 리포푸신 제거용 조성물 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4810499A (en) * | 1984-10-01 | 1989-03-07 | Biotek, Inc. | Transdermal drug delivery system and method |
| JPS6468327A (en) * | 1987-09-08 | 1989-03-14 | Teisan Seiyaku Kk | Warming type insulin-containing plaster |
| GB9513371D0 (en) * | 1995-06-30 | 1995-09-06 | Biocine Spa | Immunogenic detoxified mutant toxins |
| JPH0679002A (ja) * | 1993-12-14 | 1994-03-22 | Hisamitsu Pharmaceut Co Inc | 経皮投与用パッチシステム |
| US5989586A (en) * | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
| US5679647A (en) * | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
| JPH07304690A (ja) * | 1994-05-13 | 1995-11-21 | Advanced Sukin Res Kenkyusho:Kk | 角質溶解剤、経皮吸収促進剤及び皮膚外用製剤 |
| JP2701005B2 (ja) * | 1994-09-07 | 1998-01-21 | 株式会社林原生物化学研究所 | 減感作剤 |
| JPH0912448A (ja) * | 1995-04-28 | 1997-01-14 | Read Chem Kk | 薬物放出制御型経皮吸収製剤 |
| WO1996037256A1 (en) * | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical patch for enhancing the delivery of compounds through the skin |
| JPH09124468A (ja) * | 1995-10-27 | 1997-05-13 | Nippon Zoki Pharmaceut Co Ltd | 薬剤内包外皮用貼付剤 |
| RS50101B (sr) * | 1996-02-24 | 2009-01-22 | Boehringer Ingelheim International Gmbh., | Farmaceutski preparati za imunomodulaciju |
| JPH1025243A (ja) * | 1996-07-09 | 1998-01-27 | Showa Denko Kk | 鎮痛消炎外用貼付剤 |
| US5980898A (en) * | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
-
1999
- 1999-02-25 DE DE69936355T patent/DE69936355T2/de not_active Expired - Lifetime
- 1999-02-25 AU AU33115/99A patent/AU3311599A/en not_active Abandoned
- 1999-02-25 AT AT03007948T patent/ATE365050T1/de active
- 1999-02-25 AT AT99936034T patent/ATE247979T1/de not_active IP Right Cessation
- 1999-02-25 EP EP99936034A patent/EP1061951B1/en not_active Expired - Lifetime
- 1999-02-25 DE DE69910743T patent/DE69910743T2/de not_active Expired - Lifetime
- 1999-02-25 CA CA2321596A patent/CA2321596C/en not_active Expired - Fee Related
- 1999-02-25 WO PCT/US1999/004128 patent/WO1999043350A1/en not_active Ceased
- 1999-02-25 BR BR9908278-0A patent/BR9908278A/pt not_active Application Discontinuation
- 1999-02-25 JP JP2000533145A patent/JP4875799B2/ja not_active Expired - Fee Related
- 1999-02-25 EP EP10012335A patent/EP2286834A3/en not_active Withdrawn
- 1999-02-25 ES ES03007948T patent/ES2289200T3/es not_active Expired - Lifetime
-
2011
- 2011-10-13 JP JP2011225680A patent/JP2012041355A/ja active Pending
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