JP2011530572A - ヨードニウム塩のフッ素化の改良 - Google Patents

ヨードニウム塩のフッ素化の改良 Download PDF

Info

Publication number
JP2011530572A
JP2011530572A JP2011522517A JP2011522517A JP2011530572A JP 2011530572 A JP2011530572 A JP 2011530572A JP 2011522517 A JP2011522517 A JP 2011522517A JP 2011522517 A JP2011522517 A JP 2011522517A JP 2011530572 A JP2011530572 A JP 2011530572A
Authority
JP
Japan
Prior art keywords
groups
solution
group
iodonium salt
fluoride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2011522517A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011530572A5 (enExample
Inventor
ウッドクラフト，ジョン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of JP2011530572A publication Critical patent/JP2011530572A/ja
Publication of JP2011530572A5 publication Critical patent/JP2011530572A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Quinoline Compounds (AREA)
JP2011522517A 2008-08-14 2009-08-13 ヨードニウム塩のフッ素化の改良 Ceased JP2011530572A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8873608P 2008-08-14 2008-08-14
GBGB0814893.4A GB0814893D0 (en) 2008-08-14 2008-08-14 Improved fluoridation of iodonium salts
GB0814893.4 2008-08-14
US61/088,736 2008-08-14
PCT/EP2009/060523 WO2010018218A2 (en) 2008-08-14 2009-08-13 Improved fluoridation of iodonium salts

Publications (2)

Publication Number Publication Date
JP2011530572A true JP2011530572A (ja) 2011-12-22
JP2011530572A5 JP2011530572A5 (enExample) 2012-08-02

Family

ID=39790785

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011522517A Ceased JP2011530572A (ja) 2008-08-14 2009-08-13 ヨードニウム塩のフッ素化の改良

Country Status (6)

Country Link
US (1) US8466313B2 (enExample)
EP (1) EP2321237A2 (enExample)
JP (1) JP2011530572A (enExample)
CN (1) CN102119135B (enExample)
GB (1) GB0814893D0 (enExample)
WO (1) WO2010018218A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016517842A (ja) * 2013-03-22 2016-06-20 トラシス エス．アー． 放射合成中間体の安定化

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9302990B2 (en) 2008-10-21 2016-04-05 Nutech Ventures Fluorination of aromatic ring systems
EP3284736B1 (en) 2008-10-21 2021-03-03 NUtech Ventures Fluorination of aromatic ring systems
US8377704B2 (en) * 2009-10-20 2013-02-19 Nutech Ventures Detection and quantification of anions
US8546578B2 (en) * 2010-02-04 2013-10-01 Nutech Ventures Iodonium Cyclophanes for SECURE arene functionalization
US20150246142A1 (en) 2012-09-25 2015-09-03 The Regents Of The University Of Michigan Imaging agents
CN109053499B (zh) * 2018-08-08 2020-12-25 上海邦高化学有限公司 一种二芳基碘盐化合物及其制备方法与应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007515465A (ja) * 2003-12-23 2007-06-14 ジーイー・ヘルスケア・リミテッド ヨードニウム塩のフッ素化におけるラジカル捕捉剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0407952D0 (en) * 2004-04-08 2004-05-12 Amersham Plc Fluoridation method
WO2007141529A1 (en) 2006-06-09 2007-12-13 Ge Healthcare Limited Fluoridation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007515465A (ja) * 2003-12-23 2007-06-14 ジーイー・ヘルスケア・リミテッド ヨードニウム塩のフッ素化におけるラジカル捕捉剤

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6014001293; Ｍｉｃｈａｅｌ　Ａ．　Ｃａｒｒｏｌ，　Ｊａｍｅｓ　Ｎａｉｒｎｅ，　Ｇｒａｈａｍ　Ｓｍｉｔｈ，　Ｄａｖｉｄ　Ａ．　Ｗｉｄｄｏｗｓｏｎ: 'Ｒａｄｉｃａｌ　ｓｃａｖｅｎｇｅｒｓ：　Ａ　ｐｒａｃｔｉｃａｌ　ｓｏｌｕｔｉｏｎ　ｔｏ　ｔｈｅ　ｒｅｐｒｏｄｕｃｉｂｉｌｉｔｙ　ｉｓｓｕｅ　ｉｎ　ｔｈｅ　ｆｌｕｏｒｉｄａｔｉｏｎ　ｏｆ　ｄｉａｒｙｌｉ' Ｊｏｕｒｎａｌ　ｏｆ　Ｆｌｕｏｒｉｎｅ　Ｃｈｅｍｉｓｔｒｙ ｖｏｌ．１２８，　Ｎｏ．２, 200702, ｐ．１２７-１３２, Ｅｌｓｅｖｉｅｒ　Ｂ．　Ｖ． *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016517842A (ja) * 2013-03-22 2016-06-20 トラシス エス．アー． 放射合成中間体の安定化

Also Published As

Publication number Publication date
WO2010018218A3 (en) 2010-04-22
CN102119135A (zh) 2011-07-06
US20110144344A1 (en) 2011-06-16
CN102119135B (zh) 2014-09-24
GB0814893D0 (en) 2008-09-17
US8466313B2 (en) 2013-06-18
WO2010018218A2 (en) 2010-02-18
EP2321237A2 (en) 2011-05-18

Similar Documents

Publication Publication Date Title
US8466313B2 (en) Fluoridation of iodonium salts
JP2007532524A (ja) フッ素化方法
US7642373B2 (en) Radical trap in fluoridation of iodonium salt
JP6154815B2 (ja) 溶出剤バイアル
JP6244303B2 (ja) １８ｆ標識生体分子の合成方法
US8129528B2 (en) Method for the use of [11 C] carbon monoxide in labeling synthesis of 11C-labelled amides using metal amides and photo-induced free radical carbonylation
JP2015530985A (ja) １８ｆ−フルシクロビンの製造
JP5865351B2 (ja) 合成方法
US8093405B2 (en) Formation of 18F and 19F fluoroarenes bearing reactive functionalities
JP5512688B2 (ja) 放射性フッ素化
Briard et al. Substitution‐reduction: an alternative process for the [18F] N‐(2‐fluoroethylation) of anilines
JP2022046502A (ja) アルキル化の方法
CN103328012A (zh) 生产F-18标记的β-淀粉样蛋白配体的方法
Tack Novel radiochemistry for positron emission tomography imaging
EP1730092A2 (en) Methods to prepare carbon-isotope organohalides with high specific radioactivity from carbon-isotope monoxide
WO2020039962A1 (ja) 放射性フッ素標識化合物の標識前駆体化合物を含有する溶液
JP2014501702A (ja) 放射性医薬品前駆体の安定化
EP1846347A1 (en) Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled compounds by thermally induced free radical carbonylation

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120618

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120618

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140121

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140421

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20141007

A045 Written measure of dismissal of application [lapsed due to lack of payment]

Free format text: JAPANESE INTERMEDIATE CODE: A045

Effective date: 20150224