JP2011529706A - 間充織間質細胞集団、ならびにそれを単離および使用する方法 - Google Patents

間充織間質細胞集団、ならびにそれを単離および使用する方法 Download PDF

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JP2011529706A
JP2011529706A JP2011522168A JP2011522168A JP2011529706A JP 2011529706 A JP2011529706 A JP 2011529706A JP 2011522168 A JP2011522168 A JP 2011522168A JP 2011522168 A JP2011522168 A JP 2011522168A JP 2011529706 A JP2011529706 A JP 2011529706A
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population
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mesenchymal stromal
stromal cells
mscs
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JP2011529706A5 (cg-RX-API-DMAC7.html
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クラウディア ラング,
クリストファー ウェステンフェルダー,
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アローキュア インコーポレイテッド
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/80Undefined extracts from animals
    • C12N2500/84Undefined extracts from animals from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2011522168A 2008-08-04 2009-08-04 間充織間質細胞集団、ならびにそれを単離および使用する方法 Pending JP2011529706A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8603308P 2008-08-04 2008-08-04
US61/086,033 2008-08-04
PCT/US2009/052733 WO2010017216A2 (en) 2008-08-04 2009-08-04 Mesenchymal stromal cell populations and methods of isolating and using same

Publications (2)

Publication Number Publication Date
JP2011529706A true JP2011529706A (ja) 2011-12-15
JP2011529706A5 JP2011529706A5 (cg-RX-API-DMAC7.html) 2012-09-20

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JP2011522168A Pending JP2011529706A (ja) 2008-08-04 2009-08-04 間充織間質細胞集団、ならびにそれを単離および使用する方法

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US (1) US20110293576A1 (cg-RX-API-DMAC7.html)
EP (1) EP2321408A4 (cg-RX-API-DMAC7.html)
JP (1) JP2011529706A (cg-RX-API-DMAC7.html)
AU (1) AU2009279736A1 (cg-RX-API-DMAC7.html)
CA (1) CA2736353A1 (cg-RX-API-DMAC7.html)
WO (1) WO2010017216A2 (cg-RX-API-DMAC7.html)

Cited By (3)

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WO2021065971A1 (ja) * 2019-09-30 2021-04-08 テルモ株式会社 凍結保存細胞の希釈用緩衝液
JPWO2022025238A1 (cg-RX-API-DMAC7.html) * 2020-07-31 2022-02-03
WO2022210514A1 (ja) 2021-03-30 2022-10-06 株式会社カネカ トリプシン阻害方法、それを用いた細胞製剤の製造方法

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EP3266453A1 (en) 2008-07-03 2018-01-10 Mayo Foundation for Medical Education and Research Treating cancer
WO2010033605A2 (en) 2008-09-16 2010-03-25 Mayo Foundation For Medical Education And Research Compositions containing platelet contents
US20120269779A1 (en) * 2009-10-30 2012-10-25 Allocure, Inc. Mesenchymal stromal cell populations and methods of using same
ES2897598T3 (es) * 2009-11-27 2022-03-01 Stempeutics Res Pvt Ltd Métodos de preparación de células madre mesenquimales, composiciones y kit de las mismas
US20130121972A1 (en) 2010-06-01 2013-05-16 Rouzbeh R. Taghizadeh Native wharton's jelly stem cells and their purification
US20120087933A1 (en) 2010-10-08 2012-04-12 Samson Tom Enhanced msc preparations
AU2012253571A1 (en) 2011-05-09 2014-01-09 Mayo Foundation For Medical Education And Research Cancer treatments
CN107746830A (zh) 2011-07-06 2018-03-02 细胞治疗有限公司 从富血小板血浆制备血小板裂解物的方法
EP2776578A1 (en) 2011-11-09 2014-09-17 Allocure, Inc. Assay for the prediction of therapeutic effectiveness or potency of mesenchymal stem cells, and methods of using same
CN104136034B (zh) * 2011-11-30 2018-04-24 安斯泰来再生医药协会 间充质基质细胞及其相关用途
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
WO2013166026A1 (en) 2012-04-30 2013-11-07 Allocure, Inc. Methods of treating acute kidney injury using mesenchymal stem cells
CN104471059B (zh) 2012-07-12 2018-04-17 珠海横琴爱姆斯坦生物科技有限公司 人胚胎干细胞衍生的间充质样干细胞、方法及其应用
AU2013327638B2 (en) 2012-10-01 2018-06-14 Mayo Foundation For Medical Education And Research Cancer treatments
WO2014193895A1 (en) 2013-05-29 2014-12-04 Allocure, Inc. Ex vivo perfusion of donor organs prior to transplantation using mesenchymal stem cells
EP3028052B1 (en) * 2013-08-01 2017-11-01 Fundación Pública Andaluza Progreso Y Salud Method for predicting treatment response and test for safe use of mesenchymal stem cells on inflammatory diseases.
CA3138143A1 (en) 2014-05-16 2015-11-19 Mayo Foundation For Medical Education And Research Cell culture media compositions for primary cells
AU2015274408A1 (en) 2014-06-13 2017-01-12 Mayo Foundation For Medical Education And Research Treating lymphomas
EA201692502A1 (ru) 2014-06-16 2017-09-29 Мэйо Фаундейшн Фор Медикал Эдьюкейшн Энд Рисерч Лечение миелом
US9446148B2 (en) 2014-10-06 2016-09-20 Mayo Foundation For Medical Education And Research Carrier-antibody compositions and methods of making and using the same
TW201707725A (zh) 2015-08-18 2017-03-01 美國馬友醫藥教育研究基金會 載體-抗體組合物及其製造及使用方法
TW201713360A (en) 2015-10-06 2017-04-16 Mayo Foundation Methods of treating cancer using compositions of antibodies and carrier proteins
WO2017120501A1 (en) 2016-01-07 2017-07-13 Mayo Foundation For Medical Education And Research Methods of treating cancer with interferon
WO2017139698A1 (en) 2016-02-12 2017-08-17 Mayo Foundation For Medical Education And Research Hematologic cancer treatments
CA3018341A1 (en) 2016-03-21 2017-09-28 Mayo Foundation For Medical Education And Research Methods for reducing toxicity of a chemotherapeutic drug
US11878061B2 (en) 2016-03-21 2024-01-23 Mayo Foundation For Medical Education And Research Methods for improving the therapeutic index for a chemotherapeutic drug
US10618969B2 (en) 2016-04-06 2020-04-14 Mayo Foundation For Medical Education And Research Carrier-binding agent compositions and methods of making and using the same
US11160876B2 (en) 2016-09-01 2021-11-02 Mayo Foundation For Medical Education And Research Methods and compositions for targeting t-cell cancers
AU2017318668A1 (en) 2016-09-01 2019-03-21 Mayo Foundation For Medical Education And Research Carrier-PD-L1 binding agent compositions for treating cancers
WO2018048815A1 (en) 2016-09-06 2018-03-15 Nantibodyfc, Llc Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins
MX2019002564A (es) 2016-09-06 2019-09-18 Mayo Found Medical Education & Res Composiciones de agente de unión de albúmina-paclitaxel y métodos de uso y elaboración de las mismas.
KR102486057B1 (ko) 2016-09-06 2023-01-10 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 Pd-l1 발현 암의 치료 방법
US20190060365A1 (en) * 2017-08-25 2019-02-28 Meridigen Biotech Co., Ltd. Pharmaceutical composition for treating chronic obstructive pulmonary disease and method thereof
WO2019102268A1 (en) 2017-11-22 2019-05-31 Mesoblast International Sarl Cellular compositions and methods of treatment i
TWI894151B (zh) 2019-06-11 2025-08-21 美商阿克松根股份有限公司 組織之濕式保存

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021065971A1 (ja) * 2019-09-30 2021-04-08 テルモ株式会社 凍結保存細胞の希釈用緩衝液
JPWO2021065971A1 (cg-RX-API-DMAC7.html) * 2019-09-30 2021-04-08
JP7582958B2 (ja) 2019-09-30 2024-11-13 テルモ株式会社 凍結保存細胞の希釈用緩衝液
JPWO2022025238A1 (cg-RX-API-DMAC7.html) * 2020-07-31 2022-02-03
WO2022025238A1 (ja) * 2020-07-31 2022-02-03 株式会社Rainbow 自家血小板由来の血小板溶解物
JP7137883B2 (ja) 2020-07-31 2022-09-15 株式会社Rainbow 自家血小板由来の血小板溶解物
WO2022210514A1 (ja) 2021-03-30 2022-10-06 株式会社カネカ トリプシン阻害方法、それを用いた細胞製剤の製造方法

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WO2010017216A8 (en) 2010-09-30
WO2010017216A2 (en) 2010-02-11
WO2010017216A3 (en) 2010-06-17
AU2009279736A1 (en) 2010-02-11
EP2321408A2 (en) 2011-05-18
EP2321408A4 (en) 2013-04-17
US20110293576A1 (en) 2011-12-01
CA2736353A1 (en) 2010-02-11

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