JP2011526622A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011526622A5 JP2011526622A5 JP2011515737A JP2011515737A JP2011526622A5 JP 2011526622 A5 JP2011526622 A5 JP 2011526622A5 JP 2011515737 A JP2011515737 A JP 2011515737A JP 2011515737 A JP2011515737 A JP 2011515737A JP 2011526622 A5 JP2011526622 A5 JP 2011526622A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- release dosage
- sustained
- sustained release
- granulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002552 dosage form Substances 0.000 claims 25
- 238000013268 sustained release Methods 0.000 claims 23
- 239000012730 sustained-release form Substances 0.000 claims 23
- 239000000463 material Substances 0.000 claims 15
- 238000013270 controlled release Methods 0.000 claims 14
- 238000005469 granulation Methods 0.000 claims 10
- 230000003179 granulation Effects 0.000 claims 10
- URKOMYMAXPYINW-UHFFFAOYSA-N quetiapine Chemical compound C1CN(CCOCCO)CCN1C1=NC2=CC=CC=C2SC2=CC=CC=C12 URKOMYMAXPYINW-UHFFFAOYSA-N 0.000 claims 8
- 229960004431 quetiapine Drugs 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 7
- 239000012453 solvate Substances 0.000 claims 7
- 229920000642 polymer Polymers 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 5
- 229940079593 drug Drugs 0.000 claims 5
- 239000008187 granular material Substances 0.000 claims 4
- 238000000338 in vitro Methods 0.000 claims 3
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 claims 2
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- 239000013543 active substance Substances 0.000 claims 2
- 229920002301 cellulose acetate Polymers 0.000 claims 2
- 230000002209 hydrophobic effect Effects 0.000 claims 2
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims 2
- 229920000058 polyacrylate Polymers 0.000 claims 2
- 238000010298 pulverizing process Methods 0.000 claims 2
- 239000008107 starch Substances 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 230000002459 sustained effect Effects 0.000 claims 2
- 229920001800 Shellac Polymers 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 235000019438 castor oil Nutrition 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 239000003925 fat Substances 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 150000002191 fatty alcohols Chemical class 0.000 claims 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 1
- 239000008172 hydrogenated vegetable oil Substances 0.000 claims 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 235000019198 oils Nutrition 0.000 claims 1
- 239000008188 pellet Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000004208 shellac Substances 0.000 claims 1
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 claims 1
- 229940113147 shellac Drugs 0.000 claims 1
- 235000013874 shellac Nutrition 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000001993 wax Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1143/KOL/2008 | 2008-07-01 | ||
| IN1143KO2008 | 2008-07-01 | ||
| PCT/IN2009/000369 WO2010001413A2 (en) | 2008-07-01 | 2009-06-29 | Sustained release pharmaceutical compositions comprising quetiapine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014125631A Division JP2014196334A (ja) | 2008-07-01 | 2014-06-18 | クエチアピンを含む徐放性医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011526622A JP2011526622A (ja) | 2011-10-13 |
| JP2011526622A5 true JP2011526622A5 (https=) | 2012-08-16 |
Family
ID=40957738
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011515737A Pending JP2011526622A (ja) | 2008-07-01 | 2009-06-29 | クエチアピンを含む徐放性医薬組成物 |
| JP2014125631A Pending JP2014196334A (ja) | 2008-07-01 | 2014-06-18 | クエチアピンを含む徐放性医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014125631A Pending JP2014196334A (ja) | 2008-07-01 | 2014-06-18 | クエチアピンを含む徐放性医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8440223B2 (https=) |
| EP (1) | EP2309994A2 (https=) |
| JP (2) | JP2011526622A (https=) |
| AU (1) | AU2009265099A1 (https=) |
| WO (1) | WO2010001413A2 (https=) |
| ZA (1) | ZA201100635B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011154118A1 (en) | 2010-06-07 | 2011-12-15 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Quetiapine prolonged-release tablets |
| TR201104977A1 (tr) * | 2011-05-23 | 2012-12-21 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Kontrollü salım gerçekleştiren kaplamaya sahip ketiapin formülasyonu. |
| DE102011115690A1 (de) | 2011-10-11 | 2013-04-11 | Acino Pharma Ag | Quetiapin enthaltende Formulierungen |
| WO2013095312A1 (en) * | 2011-12-19 | 2013-06-27 | Mahmut Bilgic | Formulations comprising quetiapine fumarate |
| DK2822541T3 (da) * | 2012-09-10 | 2019-01-02 | Pharmathen Sa | Farmaceutisk sammensætning omfattende et atypisk antipsykotisk middel og fremgangsmåde til fremstilling deraf |
| WO2014155387A1 (en) * | 2013-03-24 | 2014-10-02 | Tushar Patel | Extended release dosage forms of quetiapine salts |
| EP2848244A1 (en) | 2013-09-16 | 2015-03-18 | Yildiz Özsoy Erginer | Extended release tablet formulations of quetiapine |
| CN104523600A (zh) * | 2014-11-21 | 2015-04-22 | 哈尔滨圣吉药业股份有限公司 | 一种富马酸喹硫平缓释微丸及其制备方法 |
| US9993486B1 (en) | 2017-06-19 | 2018-06-12 | Tlc Therapeutics, Llc | Oral quetiapine suspension formulations with extended shelf life and enhanced bioavailability |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607684D0 (en) | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| JPH0658877A (ja) * | 1992-08-11 | 1994-03-04 | Daicel Chem Ind Ltd | 酢酸セルロース中のゲル量の評価方法 |
| JP2006219502A (ja) * | 1994-04-22 | 2006-08-24 | Astellas Pharma Inc | 結腸特異的薬物放出システム |
| US5948437A (en) * | 1996-05-23 | 1999-09-07 | Zeneca Limited | Pharmaceutical compositions using thiazepine |
| US6962717B1 (en) * | 1999-01-29 | 2005-11-08 | Disphar International B.V. | Pharmaceutical compositions |
| US20050158383A1 (en) * | 2003-10-21 | 2005-07-21 | Garth Boehm | Quetiapine formulations |
| AR057422A1 (es) * | 2005-06-29 | 2007-12-05 | Panacea Biotec Ltd | Uan composicion farmaceutica de liberacion modificada, proceso de preparacion de dicha composicion y metodo para emplear la misma |
| PL2457563T3 (pl) | 2006-05-09 | 2017-09-29 | Mallinckrodt Llc | Stałe postacie dawkowania o zmodyfikowanym uwalnianiu rzędu zerowego |
| EP2114380A1 (en) * | 2007-01-25 | 2009-11-11 | Panacea Biotec Ltd. | Modified release pharmaceutical composition and a process of making the same |
| EP2268283A2 (en) * | 2008-03-12 | 2011-01-05 | Dexcel Ltd. | Oral modified-release formulations containing thiazepines |
| US7794750B2 (en) | 2008-06-20 | 2010-09-14 | Mutual Pharmaceutical Company, Inc. | Controlled-release formulations, method of manufacture, and use thereof |
| EP2262486B1 (en) * | 2008-08-01 | 2013-01-02 | KRKA, Tovarna Zdravil, D.D., Novo Mesto | Quetiapine composition |
-
2009
- 2009-06-29 AU AU2009265099A patent/AU2009265099A1/en not_active Abandoned
- 2009-06-29 US US13/002,277 patent/US8440223B2/en not_active Expired - Fee Related
- 2009-06-29 WO PCT/IN2009/000369 patent/WO2010001413A2/en not_active Ceased
- 2009-06-29 EP EP09773067A patent/EP2309994A2/en not_active Withdrawn
- 2009-06-29 JP JP2011515737A patent/JP2011526622A/ja active Pending
-
2011
- 2011-01-25 ZA ZA2011/00635A patent/ZA201100635B/en unknown
-
2014
- 2014-06-18 JP JP2014125631A patent/JP2014196334A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011526622A5 (https=) | ||
| JP2012021024A5 (https=) | ||
| JP2511054B2 (ja) | 徐放性の経口医薬用固形組成物及びその調製基剤 | |
| KR101476574B1 (ko) | 서방성 하이드로코돈 제형 | |
| US5169645A (en) | Directly compressible granules having improved flow properties | |
| US20070098795A1 (en) | Pharmaceutical formulation | |
| RU2010129907A (ru) | Лекарственная форма с контролируемым высвобождением, предотвращающая неправильное употребление | |
| CA2798700C (en) | Alcohol-resistant formulations | |
| NZ609840A (en) | Process for making multiparticulate gastroretentive dosage forms | |
| CN1514721A (zh) | 一日服用一次的羟考酮制剂 | |
| EP2393483A1 (en) | Pharmaceutical compositions comprising brivaracetam | |
| RU2015110824A (ru) | Фармацевтическая или нутрицевтическая композиция с замедленным высвобождением и стойкостью к воздействию этанола | |
| JP2006516969A (ja) | 徐放性製剤及びその製造方法 | |
| CA2873949A1 (en) | Dosage forms comprising apixaban and matrix former | |
| RU2015143515A (ru) | Твердые таблетки и капсулы модифицированного высвобождения бензонатата | |
| EP2153834A2 (en) | Extended release pharmaceutical compositions comprising quetiapine salts | |
| JP2014196334A (ja) | クエチアピンを含む徐放性医薬組成物 | |
| CN101690719A (zh) | 一种硫酸氢氯吡格雷的固体制剂、其颗粒及其制备方法 | |
| CN102579384B (zh) | 别嘌醇缓释微丸片及其制备方法 | |
| WO2014167440A1 (en) | Modified release pharmaceutical compositions of cyclobenzaprine or salts thereof | |
| CN102091053A (zh) | 一种颗粒组合控释片 | |
| WO2010115475A1 (en) | Process for producing rapidly disintegrating spheroids (pellets), granules and/or mixtures thereof | |
| CN102440963A (zh) | 一种别嘌醇缓释微丸及其制备方法 | |
| CN102406619A (zh) | 一种缓释微丸及其制备方法 | |
| RU2009124922A (ru) | Фармацевтическая композиция мемантина |