JP2011523658A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011523658A5 JP2011523658A5 JP2011512193A JP2011512193A JP2011523658A5 JP 2011523658 A5 JP2011523658 A5 JP 2011523658A5 JP 2011512193 A JP2011512193 A JP 2011512193A JP 2011512193 A JP2011512193 A JP 2011512193A JP 2011523658 A5 JP2011523658 A5 JP 2011523658A5
- Authority
- JP
- Japan
- Prior art keywords
- chiral
- borane
- complex
- derived
- oxazaborolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1172MU2008 | 2008-06-02 | ||
| IN1172/MUM/2008 | 2008-06-02 | ||
| PCT/GB2009/001373 WO2009147383A1 (en) | 2008-06-02 | 2009-06-02 | Process for the synthesis of arformoterol |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014222408A Division JP2015063529A (ja) | 2008-06-02 | 2014-10-31 | アルホルモテロールの合成方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011523658A JP2011523658A (ja) | 2011-08-18 |
| JP2011523658A5 true JP2011523658A5 (enExample) | 2012-06-21 |
Family
ID=40839516
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011512193A Pending JP2011523658A (ja) | 2008-06-02 | 2009-06-02 | アルホルモテロールの合成方法 |
| JP2014222408A Pending JP2015063529A (ja) | 2008-06-02 | 2014-10-31 | アルホルモテロールの合成方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014222408A Pending JP2015063529A (ja) | 2008-06-02 | 2014-10-31 | アルホルモテロールの合成方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9029421B2 (enExample) |
| EP (1) | EP2285770B1 (enExample) |
| JP (2) | JP2011523658A (enExample) |
| KR (1) | KR20110015449A (enExample) |
| AU (1) | AU2009253877B2 (enExample) |
| CA (1) | CA2724882A1 (enExample) |
| ES (1) | ES2539947T3 (enExample) |
| NZ (1) | NZ589497A (enExample) |
| WO (1) | WO2009147383A1 (enExample) |
| ZA (1) | ZA201008222B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110015449A (ko) | 2008-06-02 | 2011-02-15 | 시플라 리미티드 | 아르포르모테롤의 합성방법 |
| US20110313199A1 (en) * | 2008-12-26 | 2011-12-22 | Actavis Group Ptc Ehf | processes for preparing substantially pure arformoterol and its intermediates |
| EP2348013A1 (en) | 2010-01-25 | 2011-07-27 | Inke, S.A. | Process for preparation of intermediates of arformoterol |
| MX355697B (es) | 2010-04-12 | 2018-04-27 | Supernus Pharmaceuticals Inc | Métodos para producir sales de viloxazina y polimorfos novedosos de las mismas. |
| MX2014011576A (es) * | 2012-04-11 | 2014-11-21 | Cipla Ltd | Composicion farmaceutica. |
| CN103664677A (zh) * | 2012-09-05 | 2014-03-26 | 中山大学 | 一种(r,r)-福莫特罗酒石酸盐的不对称合成方法 |
| CN106518690A (zh) * | 2016-09-21 | 2017-03-22 | 北京万全德众医药生物技术有限公司 | 酒石酸阿福特罗重要中间体的一种制备方法 |
| CN106565527A (zh) * | 2016-11-02 | 2017-04-19 | 北京万全德众医药生物技术有限公司 | 一种酒石酸阿福特罗甲酰胺中间体的制备方法 |
| CN107673957B (zh) * | 2017-10-13 | 2020-10-23 | 河北工业大学 | 一种酸碱双功能离子液体催化低碳醛羟醛自缩合反应的方法 |
| CN109627173A (zh) * | 2019-01-19 | 2019-04-16 | 西南石油大学 | 一种氢转移选择性还原腈类制备仲胺的方法 |
| CN112574055B (zh) * | 2019-09-30 | 2024-07-09 | 天津天药药业股份有限公司 | 福莫特罗及其药用盐的制备方法及应用 |
| CN113717060B (zh) * | 2021-09-03 | 2024-03-15 | 成都新恒创药业有限公司 | 一种去甲肾上腺素及其重酒石酸盐的合成方法 |
| CN115873909B (zh) * | 2022-12-06 | 2023-08-11 | 天津法莫西生物医药科技有限公司 | 一种阿福特罗手性中间体的制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3994974A (en) * | 1972-02-05 | 1976-11-30 | Yamanouchi Pharmaceutical Co., Ltd. | α-Aminomethylbenzyl alcohol derivatives |
| JP3167705B2 (ja) * | 1990-05-21 | 2001-05-21 | 広栄化学工業株式会社 | ３―（ｎ―ベンジル―ｎ―アルコキシカルボニルアルキルアミノ）プロピオン酸エステルの製法 |
| WO1995012572A1 (en) | 1993-11-04 | 1995-05-11 | Abbott Laboratories | Cyclobutane derivatives as inhibitors of squalene synthetase and protein farnesyltransferase |
| SE9404080L (sv) | 1993-12-28 | 1995-06-29 | Ciba Geigy Ag | Förfarande för framställning av en optiskt ren enantiomer av formoterol |
| EP0938467B1 (en) * | 1996-11-11 | 2002-06-12 | Sepracor, Inc. | Process for the preparation of optically pure isomers of formoterol |
| US6040344A (en) * | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
| US5965622A (en) * | 1998-06-23 | 1999-10-12 | Sepracor Inc. | Desformoterol and process for its preparation |
| JP2000239237A (ja) * | 1999-02-19 | 2000-09-05 | Yamanouchi Pharmaceut Co Ltd | 光学活性化合物の結晶及びその製法 |
| JP2002255910A (ja) * | 2001-02-27 | 2002-09-11 | Nippon Kayaku Co Ltd | １，１ービス（３−アミノー４ーヒドロキシフェニル）シクロアルカン類の製造方法 |
| GB0118238D0 (en) * | 2001-07-26 | 2001-09-19 | Smithkline Beecham Plc | Medicaments |
| GB2380996A (en) | 2001-09-19 | 2003-04-23 | Novartis Ag | Hydroxy-nitrobenzene derivatives useful in the preparation of formoterol |
| CN1805926A (zh) * | 2003-05-05 | 2006-07-19 | 兰贝克赛实验室有限公司 | 二苯基氮杂环丁酮衍生物的反式异构体的制备方法 |
| GB0407908D0 (en) | 2004-04-07 | 2004-05-12 | Univ York | Ionic liquids |
| JP4924034B2 (ja) | 2004-05-24 | 2012-04-25 | 和光純薬工業株式会社 | イオン性液体担持クラウン化合物 |
| WO2008035380A2 (en) | 2006-09-19 | 2008-03-27 | Natco Pharma Limited | An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts |
| KR20110015449A (ko) | 2008-06-02 | 2011-02-15 | 시플라 리미티드 | 아르포르모테롤의 합성방법 |
-
2009
- 2009-06-02 KR KR1020107029606A patent/KR20110015449A/ko not_active Abandoned
- 2009-06-02 ES ES09757755.5T patent/ES2539947T3/es active Active
- 2009-06-02 CA CA2724882A patent/CA2724882A1/en not_active Abandoned
- 2009-06-02 US US12/995,016 patent/US9029421B2/en not_active Expired - Fee Related
- 2009-06-02 AU AU2009253877A patent/AU2009253877B2/en not_active Ceased
- 2009-06-02 EP EP20090757755 patent/EP2285770B1/en not_active Not-in-force
- 2009-06-02 JP JP2011512193A patent/JP2011523658A/ja active Pending
- 2009-06-02 NZ NZ589497A patent/NZ589497A/xx not_active IP Right Cessation
- 2009-06-02 WO PCT/GB2009/001373 patent/WO2009147383A1/en not_active Ceased
-
2010
- 2010-11-17 ZA ZA2010/08222A patent/ZA201008222B/en unknown
-
2014
- 2014-10-31 JP JP2014222408A patent/JP2015063529A/ja active Pending
-
2015
- 2015-04-10 US US14/683,918 patent/US20150210629A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011523658A5 (enExample) | ||
| US9174930B2 (en) | Preparation of sitagliptin intermediates | |
| CA2765566A1 (en) | Method for preparation of carbamic acid (r)-1-aryl-2-tetrazolyl-ethyl ester | |
| CN102321038B (zh) | 一种改进的制备缬沙坦方法 | |
| CN103664677A (zh) | 一种(r,r)-福莫特罗酒石酸盐的不对称合成方法 | |
| US9745309B2 (en) | Method for preparing a sitagliptin intermediate | |
| CN102241670B (zh) | 一种高纯度手性亚砜类化合物的制备方法 | |
| WO1992009545A2 (en) | New methods for the catalytic reduction of organic substrates | |
| CN103540625B (zh) | 酶促合成伊伐布雷定的中间体的方法以及在合成伊伐布雷定和其盐中的应用 | |
| CN103159633B (zh) | 他喷他多的制备方法及用于制备他喷他多的化合物 | |
| CN102766058A (zh) | 光活性的α－氨基酸的合成方法 | |
| CN102199098B (zh) | 一种合成(r)-n-苄基-1-(4-甲氧基苯基)-2-丙胺的方法及其应用 | |
| CN103951588B (zh) | 一种合成沙格列汀中间体n-叔丁氧羰基-3-羟基-1-金刚烷基-d-甘氨酸的方法 | |
| CN109942514B (zh) | 一种制备硫酸阿扎拉韦中间体的方法 | |
| CN103288671B (zh) | 一种(3s)-3-氨基-n-环丙基-2-羟基己酰胺盐酸盐的合成方法 | |
| CN1196046A (zh) | 旋光性酰胺的裂解 | |
| JP2007519655A (ja) | 鏡像異性的に純粋なアミノアルコールの調製方法 | |
| WO2011033366A8 (en) | Improved process for the preparation of duloxetine and its pharmaceutically acceptable salt | |
| CN105732445B (zh) | 达泊西汀中间体及其制备方法 | |
| CN103739483B (zh) | 一种反式-(1r,2r)-2-(3,4-二氟苯基)-1-环丙烷甲酸的制备方法 | |
| CN1182102C (zh) | 光学活性酰胺的水解方法 | |
| CN102295579B (zh) | 一种(r)-4-氰基-3-羟基丁酸乙酯的合成工艺 | |
| KR101253106B1 (ko) | 키랄 옥실레인을 이용한 시타글립틴 중간체의 제조방법 | |
| JP2008125364A5 (enExample) | ||
| CN102046602A (zh) | 制备孟鲁司特中间体的方法 |