JP2011521962A - メラニン凝集ホルモン受容体−１アンタゴニストとしてのヒドロキシ置換チエノピリミジノン - Google Patents

メラニン凝集ホルモン受容体−１アンタゴニストとしてのヒドロキシ置換チエノピリミジノン Download PDF

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Publication number
JP2011521962A
JP2011521962A JP2011511814A JP2011511814A JP2011521962A JP 2011521962 A JP2011521962 A JP 2011521962A JP 2011511814 A JP2011511814 A JP 2011511814A JP 2011511814 A JP2011511814 A JP 2011511814A JP 2011521962 A JP2011521962 A JP 2011521962A
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Prior art keywords
compound
prodrug
mmol
agent
alkyl
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JP2011511814A
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Japanese (ja)
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JP2011521962A5 (https=
Inventor
ウィリアム・エヌ・ウォッシュバーン
サリーム・アフマド
プラティック・デバスセイル
ジェフリー・エイ・ロブル
アニメシュ・ゴズワミ
ジウェイ・グオ
ラメシュ・エヌ・ペイテル
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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Publication of JP2011521962A publication Critical patent/JP2011521962A/ja
Publication of JP2011521962A5 publication Critical patent/JP2011521962A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP2011511814A 2008-05-29 2009-05-28 メラニン凝集ホルモン受容体−１アンタゴニストとしてのヒドロキシ置換チエノピリミジノン Withdrawn JP2011521962A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5694908P 2008-05-29 2008-05-29
US61/056,949 2008-05-29
PCT/US2009/045452 WO2009146365A1 (en) 2008-05-29 2009-05-28 Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists

Publications (2)

Publication Number Publication Date
JP2011521962A true JP2011521962A (ja) 2011-07-28
JP2011521962A5 JP2011521962A5 (https=) 2011-10-06

Family

ID=41017166

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011511814A Withdrawn JP2011521962A (ja) 2008-05-29 2009-05-28 メラニン凝集ホルモン受容体−１アンタゴニストとしてのヒドロキシ置換チエノピリミジノン

Country Status (17)

Country Link
US (1) US7989433B2 (https=)
EP (1) EP2310394A1 (https=)
JP (1) JP2011521962A (https=)
KR (1) KR20110021988A (https=)
CN (1) CN102099360A (https=)
AR (1) AR075260A1 (https=)
AU (1) AU2009251331A1 (https=)
BR (1) BRPI0913197A2 (https=)
CA (1) CA2726264A1 (https=)
CO (1) CO6280492A2 (https=)
EA (1) EA201001882A1 (https=)
IL (1) IL209354A0 (https=)
MX (1) MX2010012803A (https=)
PE (1) PE20091928A1 (https=)
TW (1) TW201000487A (https=)
WO (1) WO2009146365A1 (https=)
ZA (1) ZA201008451B (https=)

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JP2010525077A (ja) * 2007-04-25 2010-07-22 ブリストル−マイヤーズ スクイブ カンパニー 非塩基性メラニン凝集ホルモン受容体−１アンタゴニスト
NZ602089A (en) 2010-02-17 2014-05-30 Takeda Pharmaceutical Heterocyclic compounds having cell division cycle 7 inhibitory activity
CA2857231A1 (en) 2011-12-06 2013-06-13 Unilever Plc Skin anti-ageing composition
IL225900A0 (en) * 2013-04-22 2014-03-31 Perrigo Api Ltd A process for the preparation of nicotine that includes the enzymatic reduction of 4-(methylamino)-1-(3-pyridinyl)-1-butanone
EP2921856B1 (en) * 2014-03-18 2016-09-14 Serum Institute Of India Private Limited A quantitative assay for 4-pyrrolidinopyridine (4-ppy) in polysaccharide-protein conjugate vaccines
RU2687160C2 (ru) * 2014-12-30 2019-05-07 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Пиколинамидные соединения с фунгицидной активностью
JP6687625B2 (ja) 2014-12-30 2020-04-22 ダウ アグロサイエンシィズ エルエルシー 殺真菌活性を有するピコリンアミド化合物
AU2021206286A1 (en) * 2020-01-10 2024-08-08 Consynance Therapeutics, Inc. Therapeutic combinations of drugs and methods of using them
HUP2200222A1 (hu) 2022-06-17 2023-12-28 Richter Gedeon Nyrt MCHR1 antagonisták a Prader-Willi szindróma kezelésére

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Also Published As

Publication number Publication date
EP2310394A1 (en) 2011-04-20
ZA201008451B (en) 2012-04-25
US20090298794A1 (en) 2009-12-03
CA2726264A1 (en) 2009-12-03
AR075260A1 (es) 2011-03-23
IL209354A0 (en) 2011-01-31
MX2010012803A (es) 2010-12-07
KR20110021988A (ko) 2011-03-04
CO6280492A2 (es) 2011-05-20
PE20091928A1 (es) 2009-12-31
CN102099360A (zh) 2011-06-15
EA201001882A1 (ru) 2011-06-30
TW201000487A (en) 2010-01-01
US7989433B2 (en) 2011-08-02
AU2009251331A1 (en) 2009-12-03
WO2009146365A1 (en) 2009-12-03
BRPI0913197A2 (pt) 2016-01-12

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