KR20110021988A - 멜라닌 농축 호르몬 수용체-1 길항제로서의 히드록시 치환된 티에노 피리미디논 - Google Patents
멜라닌 농축 호르몬 수용체-1 길항제로서의 히드록시 치환된 티에노 피리미디논 Download PDFInfo
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- KR20110021988A KR20110021988A KR1020107029384A KR20107029384A KR20110021988A KR 20110021988 A KR20110021988 A KR 20110021988A KR 1020107029384 A KR1020107029384 A KR 1020107029384A KR 20107029384 A KR20107029384 A KR 20107029384A KR 20110021988 A KR20110021988 A KR 20110021988A
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- ZEWQUBUPAILYHI-UHFFFAOYSA-N trifluoperazine Chemical compound C1CN(C)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 ZEWQUBUPAILYHI-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
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| US5694908P | 2008-05-29 | 2008-05-29 | |
| US61/056,949 | 2008-05-29 |
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| KR20110021988A true KR20110021988A (ko) | 2011-03-04 |
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Family Applications (1)
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| KR1020107029384A Withdrawn KR20110021988A (ko) | 2008-05-29 | 2009-05-28 | 멜라닌 농축 호르몬 수용체-1 길항제로서의 히드록시 치환된 티에노 피리미디논 |
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| EP (1) | EP2310394A1 (https=) |
| JP (1) | JP2011521962A (https=) |
| KR (1) | KR20110021988A (https=) |
| CN (1) | CN102099360A (https=) |
| AR (1) | AR075260A1 (https=) |
| AU (1) | AU2009251331A1 (https=) |
| BR (1) | BRPI0913197A2 (https=) |
| CA (1) | CA2726264A1 (https=) |
| CO (1) | CO6280492A2 (https=) |
| EA (1) | EA201001882A1 (https=) |
| IL (1) | IL209354A0 (https=) |
| MX (1) | MX2010012803A (https=) |
| PE (1) | PE20091928A1 (https=) |
| TW (1) | TW201000487A (https=) |
| WO (1) | WO2009146365A1 (https=) |
| ZA (1) | ZA201008451B (https=) |
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| JP2010525077A (ja) * | 2007-04-25 | 2010-07-22 | ブリストル−マイヤーズ スクイブ カンパニー | 非塩基性メラニン凝集ホルモン受容体−１アンタゴニスト |
| NZ602089A (en) | 2010-02-17 | 2014-05-30 | Takeda Pharmaceutical | Heterocyclic compounds having cell division cycle 7 inhibitory activity |
| CA2857231A1 (en) | 2011-12-06 | 2013-06-13 | Unilever Plc | Skin anti-ageing composition |
| IL225900A0 (en) * | 2013-04-22 | 2014-03-31 | Perrigo Api Ltd | A process for the preparation of nicotine that includes the enzymatic reduction of 4-(methylamino)-1-(3-pyridinyl)-1-butanone |
| EP2921856B1 (en) * | 2014-03-18 | 2016-09-14 | Serum Institute Of India Private Limited | A quantitative assay for 4-pyrrolidinopyridine (4-ppy) in polysaccharide-protein conjugate vaccines |
| RU2687160C2 (ru) * | 2014-12-30 | 2019-05-07 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Пиколинамидные соединения с фунгицидной активностью |
| JP6687625B2 (ja) | 2014-12-30 | 2020-04-22 | ダウ アグロサイエンシィズ エルエルシー | 殺真菌活性を有するピコリンアミド化合物 |
| AU2021206286A1 (en) * | 2020-01-10 | 2024-08-08 | Consynance Therapeutics, Inc. | Therapeutic combinations of drugs and methods of using them |
| HUP2200222A1 (hu) | 2022-06-17 | 2023-12-28 | Richter Gedeon Nyrt | MCHR1 antagonisták a Prader-Willi szindróma kezelésére |
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| US3674836A (en) | 1968-05-21 | 1972-07-04 | Parke Davis & Co | 2,2-dimethyl-{11 -aryloxy-alkanoic acids and salts and esters thereof |
| US4027009A (en) | 1973-06-11 | 1977-05-31 | Merck & Co., Inc. | Compositions and methods for depressing blood serum cholesterol |
| JPS5612114B2 (https=) | 1974-06-07 | 1981-03-18 | ||
| JPS5432794A (en) | 1977-08-18 | 1979-03-10 | Omron Tateisi Electronics Co | Manufacturing method of terminal rack |
| NO154918C (no) | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
| US4231938A (en) | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
| DE2951135A1 (de) | 1979-12-19 | 1981-06-25 | Hoechst Ag, 6230 Frankfurt | Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
| MX7065E (es) | 1980-06-06 | 1987-04-10 | Sankyo Co | Un procedimiento microbiologico para preparar derivados de ml-236b |
| US4450171A (en) | 1980-08-05 | 1984-05-22 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| US4448784A (en) | 1982-04-12 | 1984-05-15 | Hoechst-Roussel Pharmaceuticals, Inc. | 1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof |
| US5354772A (en) | 1982-11-22 | 1994-10-11 | Sandoz Pharm. Corp. | Indole analogs of mevalonolactone and derivatives thereof |
| US4499289A (en) | 1982-12-03 | 1985-02-12 | G. D. Searle & Co. | Octahydronapthalenes |
| CA1327360C (en) | 1983-11-14 | 1994-03-01 | William F. Hoffman | Oxo-analogs of mevinolin-like antihypercholesterolemic agents |
| US4613610A (en) | 1984-06-22 | 1986-09-23 | Sandoz Pharmaceuticals Corp. | Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives |
| US4686237A (en) | 1984-07-24 | 1987-08-11 | Sandoz Pharmaceuticals Corp. | Erythro-(E)-7-[3'-C1-3 alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl]-3,5-dihydroxyhept-6-enoic acids and derivatives thereof |
| US4647576A (en) | 1984-09-24 | 1987-03-03 | Warner-Lambert Company | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis |
| EP0216785B1 (en) | 1984-12-04 | 1991-01-30 | Sandoz Ag | Indene analogs of mevalonolactone and derivatives thereof |
| HUT48208A (en) | 1985-10-25 | 1989-05-29 | Sandoz Ag | Process for producing heterocyclic analogues of mevalolactone derivatives and pharmaceutical compositions comprising such compounds |
| DE3543999A1 (de) | 1985-12-13 | 1987-06-19 | Bayer Ag | Hochreine acarbose |
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| FI89493C (fi) | 1987-05-22 | 1993-10-11 | Squibb & Sons Inc | Foerfarande foer framstaellning av terapeutiskt aktiva, fosforhaltiga inhibitorer av hmg-coa-reduktas och vid foerfarandet anvaendbar ny mellanprodukt |
| US4759923A (en) | 1987-06-25 | 1988-07-26 | Hercules Incorporated | Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives |
| JP2569746B2 (ja) | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
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| LT3300B (en) | 1992-12-23 | 1995-06-26 | Schering Corp | Combination of a cholesterol biosynhtesis inhibitor and a beta- lactam cholesterol absorbtion inhibitor |
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-
2009
- 2009-05-27 PE PE2009000744A patent/PE20091928A1/es not_active Application Discontinuation
- 2009-05-28 CA CA2726264A patent/CA2726264A1/en not_active Abandoned
- 2009-05-28 EP EP09755726A patent/EP2310394A1/en not_active Withdrawn
- 2009-05-28 EA EA201001882A patent/EA201001882A1/ru unknown
- 2009-05-28 US US12/473,346 patent/US7989433B2/en active Active
- 2009-05-28 BR BRPI0913197A patent/BRPI0913197A2/pt not_active Application Discontinuation
- 2009-05-28 MX MX2010012803A patent/MX2010012803A/es not_active Application Discontinuation
- 2009-05-28 AU AU2009251331A patent/AU2009251331A1/en not_active Abandoned
- 2009-05-28 CN CN2009801280666A patent/CN102099360A/zh active Pending
- 2009-05-28 WO PCT/US2009/045452 patent/WO2009146365A1/en not_active Ceased
- 2009-05-28 JP JP2011511814A patent/JP2011521962A/ja not_active Withdrawn
- 2009-05-28 AR ARP090101925A patent/AR075260A1/es unknown
- 2009-05-28 KR KR1020107029384A patent/KR20110021988A/ko not_active Withdrawn
- 2009-06-01 TW TW098118073A patent/TW201000487A/zh unknown
-
2010
- 2010-11-16 IL IL209354A patent/IL209354A0/en unknown
- 2010-11-24 ZA ZA2010/08451A patent/ZA201008451B/en unknown
- 2010-11-30 CO CO10151012A patent/CO6280492A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011521962A (ja) | 2011-07-28 |
| EP2310394A1 (en) | 2011-04-20 |
| ZA201008451B (en) | 2012-04-25 |
| US20090298794A1 (en) | 2009-12-03 |
| CA2726264A1 (en) | 2009-12-03 |
| AR075260A1 (es) | 2011-03-23 |
| IL209354A0 (en) | 2011-01-31 |
| MX2010012803A (es) | 2010-12-07 |
| CO6280492A2 (es) | 2011-05-20 |
| PE20091928A1 (es) | 2009-12-31 |
| CN102099360A (zh) | 2011-06-15 |
| EA201001882A1 (ru) | 2011-06-30 |
| TW201000487A (en) | 2010-01-01 |
| US7989433B2 (en) | 2011-08-02 |
| AU2009251331A1 (en) | 2009-12-03 |
| WO2009146365A1 (en) | 2009-12-03 |
| BRPI0913197A2 (pt) | 2016-01-12 |
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