|
US4444744A
(en)
|
1980-03-03 |
1984-04-24 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibodies to cell surface antigens
|
|
DE3407582A1
(de)
|
1984-03-01 |
1985-09-05 |
Dornier System Gmbh, 7990 Friedrichshafen |
Schaltungsanordnung fuer einen regelkreis
|
|
AU617652B2
(en)
|
1986-09-19 |
1991-12-05 |
Scripps Clinic And Research Foundation |
Monoclonal paratopic molecule directed to human ganglioside gd2
|
|
US5591829A
(en)
|
1987-05-29 |
1997-01-07 |
Matsushita; Shuzo |
Antibodies modified with toxic substance
|
|
US5051364A
(en)
|
1989-02-16 |
1991-09-24 |
The Salk Institute For Biological Studies |
Anti-lipocortin-I and anti-lipocortin-II monoclonal antibodies
|
|
DE3909799A1
(de)
|
1989-03-24 |
1990-09-27 |
Behringwerke Ag |
Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
|
|
EP0491007B1
(en)
|
1989-09-08 |
1996-03-13 |
The Johns Hopkins University |
Structural alterations of the egf receptor gene in human gliomas
|
|
US5223253A
(en)
|
1989-09-28 |
1993-06-29 |
American Home Products Corporation |
Bovine vaccine compositions and method for preventing trichomonas infections using same
|
|
GB2250993B
(en)
|
1990-11-21 |
1995-02-15 |
Inst Nat Sante Rech Med |
Stromelysin-3 and its application in the diagnosis and treatment of malignant breast cancer
|
|
US5750376A
(en)
|
1991-07-08 |
1998-05-12 |
Neurospheres Holdings Ltd. |
In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
|
|
AU679167B2
(en)
|
1991-09-20 |
1997-06-26 |
Amgen, Inc. |
Glial derived neurotrophic factor
|
|
US5314992A
(en)
|
1991-11-25 |
1994-05-24 |
Trustees Of Dartmouth College |
Lipocortin-1 receptor protein and its uses
|
|
EP0642353A1
(en)
|
1992-05-14 |
1995-03-15 |
Oncologix, Inc. |
Treatment of vascular leakage syndrome and collagenase induced disease by administration of matrix metalloproteinase inhibitors
|
|
EP0922458A1
(en)
|
1993-01-14 |
1999-06-16 |
Cancer Research Campaign Technology Limited |
Potentiation of temozolomide by an ATase inhibitor
|
|
US5626862A
(en)
|
1994-08-02 |
1997-05-06 |
Massachusetts Institute Of Technology |
Controlled local delivery of chemotherapeutic agents for treating solid tumors
|
|
US5688773A
(en)
|
1994-08-17 |
1997-11-18 |
The General Hospital Corporation |
Method of selectively destroying neoplastic cells
|
|
US5985822A
(en)
|
1994-12-09 |
1999-11-16 |
The Scripps Research Institute |
Inhibition of glial cell proliferation with N-CAM homophilic peptides
|
|
US5756340A
(en)
|
1995-05-08 |
1998-05-26 |
The Regents Of The University Of California |
Insect control with multiple toxins
|
|
JP3809502B2
(ja)
|
1995-05-30 |
2006-08-16 |
二郎 有川 |
ハンタウィルス抗原蛋白質およびモノクローナル抗体
|
|
JPH0971599A
(ja)
|
1995-09-06 |
1997-03-18 |
Nippon Seibutsu Kagaku Kenkyusho |
鶏貧血ウイルス（ｃａｖ）感染鶏血清と高い反応性を示すポリペプチド及びこのポリペプチドに対する抗体、鶏貧血ウイルス感染の診断法及びワクチン
|
|
US6667156B2
(en)
*
|
1995-12-27 |
2003-12-23 |
Uab Research Foundation |
Diagnosis and treatment of neuroectodermal tumors
|
|
US5905027A
(en)
|
1995-12-27 |
1999-05-18 |
Uab Research Foundation |
Method of diagnosing and treating gliomas
|
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
|
US6130101A
(en)
|
1997-09-23 |
2000-10-10 |
Molecular Probes, Inc. |
Sulfonated xanthene derivatives
|
|
US6555652B1
(en)
|
1997-12-05 |
2003-04-29 |
Kyogo Itoh |
Tumor antigen peptide derivatives
|
|
US6703381B1
(en)
|
1998-08-14 |
2004-03-09 |
Nobex Corporation |
Methods for delivery therapeutic compounds across the blood-brain barrier
|
|
US6214986B1
(en)
|
1998-10-07 |
2001-04-10 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of bcl-x expression
|
|
SE9901387D0
(sv)
|
1999-04-19 |
1999-04-19 |
Astra Ab |
New pharmaceutical foromaulations
|
|
US6849714B1
(en)
|
1999-05-17 |
2005-02-01 |
Conjuchem, Inc. |
Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
|
|
CA2384429A1
(en)
|
1999-09-14 |
2001-03-22 |
Michael K. Bahr |
Magnetic nanoparticles having biochemical activity, method for the production thereof and their use
|
|
WO2001037721A2
(en)
|
1999-11-22 |
2001-05-31 |
The Research Foundation Of State University Of New York |
Magnetic nanoparticles for selective therapy
|
|
DE10020376A1
(de)
|
2000-04-26 |
2001-11-08 |
Inst Zelltechnologie E V |
Dynamische Marker
|
|
AU2002252160A1
(en)
|
2001-03-01 |
2002-09-19 |
Northwest Biotherapeutics, Inc. |
Connexin enhances chemotherapy-induced apoptosis in human cancer cells inhibiting tumor cell proliferation
|
|
WO2003008583A2
(en)
|
2001-03-02 |
2003-01-30 |
Sagres Discovery |
Novel compositions and methods for cancer
|
|
US20030021810A1
(en)
|
2001-06-26 |
2003-01-30 |
Sontheimer Harald W. |
Chlorotoxin inhibition of cell invasion, cancer metastasis, angiogenesis and tissue remodeling
|
|
WO2003029462A1
(en)
|
2001-09-27 |
2003-04-10 |
Pieris Proteolab Ag |
Muteins of human neutrophil gelatinase-associated lipocalin and related proteins
|
|
US6972326B2
(en)
|
2001-12-03 |
2005-12-06 |
Molecular Probes, Inc. |
Labeling of immobilized proteins using dipyrrometheneboron difluoride dyes
|
|
AU2003207835A1
(en)
|
2002-02-04 |
2003-09-02 |
Auburn University |
Peptides for recognition and targeting of glial cell tumors
|
|
US20030232013A1
(en)
|
2002-02-22 |
2003-12-18 |
Gary Sieckman |
Therapeutic and diagnostic targeting of cancers cells with tumor homing peptides
|
|
US20060088899A1
(en)
|
2002-05-31 |
2006-04-27 |
Alvarez Vernon L |
Combination chemotherapy with chlorotoxin
|
|
AU2003237347B2
(en)
|
2002-05-31 |
2009-07-23 |
Transmolecular Inc. |
Treatment of cell proliferative disorders with chlorotoxin
|
|
US7560160B2
(en)
|
2002-11-25 |
2009-07-14 |
Materials Modification, Inc. |
Multifunctional particulate material, fluid, and composition
|
|
US20040101822A1
(en)
|
2002-11-26 |
2004-05-27 |
Ulrich Wiesner |
Fluorescent silica-based nanoparticles
|
|
US20060019256A1
(en)
|
2003-06-09 |
2006-01-26 |
The Regents Of The University Of Michigan |
Compositions and methods for treating and diagnosing cancer
|
|
DE10328251A1
(de)
|
2003-06-24 |
2005-01-13 |
Toximed Gmbh |
Pharmazeutischer Wirkstoff
|
|
WO2005053611A2
(en)
|
2003-11-26 |
2005-06-16 |
Transmolecular, Inc. |
Treatment of phosphatidylinositol phospholipid disorders
|
|
AU2005232616A1
(en)
|
2004-04-06 |
2005-10-27 |
Transmolecular, Inc. |
Diagnosis and treatment of myeloid and lymphoid cell cancers
|
|
US20080153746A1
(en)
*
|
2004-04-06 |
2008-06-26 |
Transmolecular, Inc. |
Diagnosis and Treatment of Myeloid and Lymphoid Cell Cancers
|
|
CA2565701A1
(en)
|
2004-05-06 |
2005-11-17 |
Jonathan M. Barasch |
Ngal for reduction and amelioration of ischemic and nephrotoxic injuries
|
|
WO2006091231A2
(en)
|
2004-07-21 |
2006-08-31 |
Ambrx, Inc. |
Biosynthetic polypeptides utilizing non-naturally encoded amino acids
|
|
GB0422901D0
(en)
|
2004-10-14 |
2004-11-17 |
Ares Trading Sa |
Lipocalin protein
|
|
KR100681763B1
(ko)
|
2005-02-28 |
2007-02-15 |
재단법인 목암생명공학연구소 |
인간 리포칼린 2를 유효성분으로 포함하는 암 전이 억제용약학적 조성물, 이를 이용한 암 전이 억제 방법
|
|
GB0504767D0
(en)
|
2005-03-08 |
2005-04-13 |
Ares Trading Sa |
Lipocalin protein
|
|
US7462446B2
(en)
|
2005-03-18 |
2008-12-09 |
University Of Washington |
Magnetic nanoparticle compositions and methods
|
|
US20070037232A1
(en)
|
2005-03-31 |
2007-02-15 |
Barasch Jonathan M |
Detection of NGAL in chronic renal disease
|
|
CA2604844A1
(en)
|
2005-04-07 |
2006-10-19 |
Novartis Vaccines And Diagnostics, Inc. |
Cancer-related genes
|
|
WO2006110582A1
(en)
|
2005-04-08 |
2006-10-19 |
Xcyte Therapies, Inc. |
Compositions and methods for the treatment of burns and sepsis
|
|
US7833979B2
(en)
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
|
DE602006020710D1
(de)
|
2005-04-22 |
2011-04-28 |
Fred Hutchinson Cancer Res Foundation |
Fluoreszentes chlorotoxinkonjugat und verfahren zur intraoperativen sichtbarmachung von krebs
|
|
AU2005335491B2
(en)
|
2005-08-18 |
2010-11-25 |
Ambrx, Inc. |
Compositions of tRNA and uses thereof
|
|
CA2647907A1
(en)
|
2006-03-31 |
2007-10-18 |
Transmolecular, Inc. |
Use of tm-601 for the diagnosis and treatment of tumors
|
|
US8106013B2
(en)
|
2006-05-19 |
2012-01-31 |
Georgia Tech Research Corporation |
ABC transporter ligand GATX1
|
|
CN100564517C
(zh)
|
2006-09-21 |
2009-12-02 |
武汉大学 |
一种蝎抗神经胶质瘤肽及其制备方法和应用
|
|
CN101003788A
(zh)
|
2006-09-21 |
2007-07-25 |
武汉大学 |
一种蝎抗肿瘤转移肽及其制备方法和应用
|
|
PE20081140A1
(es)
|
2006-10-25 |
2008-09-22 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
|
SI2173890T1
(sl)
|
2007-06-21 |
2011-06-30 |
Univ Muenchen Tech |
Biološko aktivni proteini, ki imajo povečano in vivo in/ali in vitro stabilnost
|
|
US20090004105A1
(en)
|
2007-06-27 |
2009-01-01 |
Zhen Cheng |
Molecular imaging of matrix metalloproteinase expression using labeled chlorotoxin
|
|
EP2173385A1
(en)
|
2007-08-07 |
2010-04-14 |
Transmolecular, Inc. |
Chlorotoxins as drug carriers
|
|
US20100215575A1
(en)
|
2007-10-12 |
2010-08-26 |
Transmolecular, Inc. |
Systemic Administration of Chlorotoxin Agents for the Diagnosis and Treatment of Tumors
|
|
US20090123946A1
(en)
|
2007-10-19 |
2009-05-14 |
Abbott Laboratories |
Immunoassays and kits for the detection of ngal
|
|
US20090124022A1
(en)
|
2007-10-19 |
2009-05-14 |
Abbott Laboratories |
Antibodies that bind to mammalian ngal and uses thereof
|
|
WO2009052400A1
(en)
|
2007-10-19 |
2009-04-23 |
Abbott Laboratories |
Antibodies that bind to mammalian ngal and uses thereof
|
|
US20090123970A1
(en)
|
2007-10-19 |
2009-05-14 |
Abbott Laboratories |
Glycosylated mammalian ngal and use thereof
|
|
US20090176274A1
(en)
|
2007-10-19 |
2009-07-09 |
Abbott Laboratories |
Glycosylated mammalian ngal and use thereof
|
|
US20090269777A1
(en)
|
2007-10-19 |
2009-10-29 |
Abbott Laboratories |
Immunoassays and kits for the detection of ngal
|
|
US8846036B2
(en)
|
2007-10-19 |
2014-09-30 |
Abbott Laboratories |
Antibodies that bind to mammalian NGAL and uses thereof
|
|
ES2475990T5
(es)
|
2007-11-15 |
2017-07-06 |
Bioporto Diagnostics A/S |
Uso diagnóstico de formas moleculares individuales de un biomarcador
|
|
WO2009108762A2
(en)
|
2008-02-26 |
2009-09-03 |
The Penn State Research Foundation |
Methods and compositions for treatment of retinoid-responsive conditions
|
|
US8470607B2
(en)
|
2008-03-20 |
2013-06-25 |
Morphotek, Inc. |
Inhibition of angiogenesis
|
|
CN101270158B
(zh)
|
2008-04-30 |
2010-12-22 |
武汉大学 |
一种靶向抗神经胶质瘤蛋白及制备方法和用途
|
|
CA2724384A1
(en)
|
2008-05-15 |
2009-11-19 |
Transmolecular, Inc. |
Treatment of metastatic tumors
|
|
DK3381933T3
(da)
|
2008-06-24 |
2020-08-03 |
Technische Universität München |
Muteiner af hngal og relaterede proteiner med affinitet til et givet mål
|
|
US20100098637A1
(en)
|
2008-09-23 |
2010-04-22 |
The Regents Of The University Of Michigan |
Dye-loaded nanoparticle
|
|
CN101381405B
(zh)
|
2008-09-24 |
2011-07-27 |
武汉摩尔生物科技有限公司 |
基因工程肿瘤靶向kct-w1多肽及制备方法和用途
|
|
US20100105150A1
(en)
|
2008-10-24 |
2010-04-29 |
Abbott Laboratories |
Isolated human autoantibodies to neutrophil gelatinase-associated lipocalin (ngal) and methods and kits for the detection of human autoantibodies to ngal
|
|
CN106519588B
(zh)
|
2009-11-09 |
2019-08-20 |
华盛顿大学商业化中心 |
官能化发色聚合物点及其生物共轭体
|
|
CN101921769B
(zh)
|
2010-01-11 |
2012-07-25 |
山西大学 |
一种重组腺病毒及其制备方法和应用
|
|
WO2011094671A2
(en)
|
2010-01-29 |
2011-08-04 |
The Uab Research Foundation |
N-terminally conjugated polypeptides for targeted therapy and diagnosis
|
|
CN102844044B
(zh)
|
2010-02-04 |
2016-10-26 |
摩尔弗泰克有限公司 |
氯毒素多肽和结合物及其应用
|
|
CN101824084A
(zh)
|
2010-04-08 |
2010-09-08 |
山西大学 |
靶向性抗胶质瘤蛋白质及其应用
|
|
EP3165533B1
(en)
|
2010-05-11 |
2020-04-08 |
Fred Hutchinson Cancer Research Center |
Chlorotoxin variants, conjugates and methods for their use
|
|
EP3299386A1
(en)
|
2010-08-16 |
2018-03-28 |
Pieris Pharmaceuticals GmbH |
Binding proteins for hepcidin
|