JP2010535811A5 - - Google Patents
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- JP2010535811A5 JP2010535811A5 JP2010520313A JP2010520313A JP2010535811A5 JP 2010535811 A5 JP2010535811 A5 JP 2010535811A5 JP 2010520313 A JP2010520313 A JP 2010520313A JP 2010520313 A JP2010520313 A JP 2010520313A JP 2010535811 A5 JP2010535811 A5 JP 2010535811A5
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- conjugate
- cancer
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| US95440907P | 2007-08-07 | 2007-08-07 | |
| PCT/US2008/072524 WO2009021136A1 (en) | 2007-08-07 | 2008-08-07 | Chlorotoxins as drug carriers |
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| JP2010535811A JP2010535811A (ja) | 2010-11-25 |
| JP2010535811A5 true JP2010535811A5 (https=) | 2011-09-22 |
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| DE602006020710D1 (de) * | 2005-04-22 | 2011-04-28 | Fred Hutchinson Cancer Res Foundation | Fluoreszentes chlorotoxinkonjugat und verfahren zur intraoperativen sichtbarmachung von krebs |
| CA2724384A1 (en) | 2008-05-15 | 2009-11-19 | Transmolecular, Inc. | Treatment of metastatic tumors |
| CN102844044B (zh) | 2010-02-04 | 2016-10-26 | 摩尔弗泰克有限公司 | 氯毒素多肽和结合物及其应用 |
| WO2011126010A1 (ja) * | 2010-04-06 | 2011-10-13 | 三菱化学株式会社 | 癌細胞選択的膜透過性ペプチドおよびその利用 |
| EP3165533B1 (en) | 2010-05-11 | 2020-04-08 | Fred Hutchinson Cancer Research Center | Chlorotoxin variants, conjugates and methods for their use |
| WO2013003507A1 (en) | 2011-06-27 | 2013-01-03 | Morphotek, Inc. | Multifunctional agents |
| CA2913029A1 (en) | 2012-12-10 | 2014-06-19 | Fred Hutchinson Cancer Research Center | Lipocalin fusion partners |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| US12048732B2 (en) | 2016-04-15 | 2024-07-30 | Blaze Bioscience, Inc. | Methods of treating breast cancer |
| US11421005B2 (en) * | 2016-12-09 | 2022-08-23 | The Uab Research Foundation | Chimeric chlorotoxin receptors |
| CN111542345B (zh) | 2017-09-15 | 2025-02-25 | 卫材公司 | 氯毒素剂及其用途 |
| CA3086040A1 (en) | 2017-12-19 | 2019-06-27 | Blaze Bioscience, Inc. | Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof |
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| US5905027A (en) * | 1995-12-27 | 1999-05-18 | Uab Research Foundation | Method of diagnosing and treating gliomas |
| US6667156B2 (en) * | 1995-12-27 | 2003-12-23 | Uab Research Foundation | Diagnosis and treatment of neuroectodermal tumors |
| AU2003237347B2 (en) * | 2002-05-31 | 2009-07-23 | Transmolecular Inc. | Treatment of cell proliferative disorders with chlorotoxin |
| US20060088899A1 (en) * | 2002-05-31 | 2006-04-27 | Alvarez Vernon L | Combination chemotherapy with chlorotoxin |
| WO2006091231A2 (en) * | 2004-07-21 | 2006-08-31 | Ambrx, Inc. | Biosynthetic polypeptides utilizing non-naturally encoded amino acids |
| DE602006020710D1 (de) * | 2005-04-22 | 2011-04-28 | Fred Hutchinson Cancer Res Foundation | Fluoreszentes chlorotoxinkonjugat und verfahren zur intraoperativen sichtbarmachung von krebs |
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2008
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- 2008-08-07 WO PCT/US2008/072524 patent/WO2009021136A1/en not_active Ceased
- 2008-08-07 AU AU2008285364A patent/AU2008285364A1/en not_active Abandoned
- 2008-08-07 JP JP2010520313A patent/JP2010535811A/ja not_active Withdrawn
- 2008-08-07 US US12/672,069 patent/US20110091380A1/en not_active Abandoned
- 2008-08-07 CA CA2696303A patent/CA2696303A1/en not_active Abandoned
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