|
WO1999015903A1
(de)
*
|
1997-09-19 |
1999-04-01 |
Evotec Biosystems Ag |
Verfahren zur messung der assoziation von teilstrukturen pathologischer proteinablagerungen
|
|
US4006117A
(en)
*
|
1973-01-24 |
1977-02-01 |
Hooker Chemicals & Plastics Corporation |
Amine phosphite antioxidants
|
|
US3843443A
(en)
*
|
1973-03-30 |
1974-10-22 |
J Fishman |
Polypeptide materials bound to fluorocarbon polymers
|
|
US4244721A
(en)
*
|
1979-01-31 |
1981-01-13 |
Pedro Buarque De Macedo |
Method of making composite borosilicate glass articles
|
|
US4507230A
(en)
*
|
1982-05-12 |
1985-03-26 |
Research Corporation |
Peptide synthesis reagents and method of use
|
|
US4952496A
(en)
*
|
1984-03-30 |
1990-08-28 |
Associated Universities, Inc. |
Cloning and expression of the gene for bacteriophage T7 RNA polymerase
|
|
DE3500180A1
(de)
*
|
1985-01-04 |
1986-07-10 |
Ernst Prof. Dr. 7400 Tübingen Bayer |
Pfropfcopolymerisate aus vernetzten polymeren und polyoxyethylen, verfahren zu ihrer herstellung und ihre verwendung
|
|
US5292814A
(en)
*
|
1987-04-29 |
1994-03-08 |
Ernst Bayer |
Process for the preparation of monodispersed polymer beads
|
|
DK0460076T3
(da)
*
|
1989-02-24 |
1996-03-25 |
Univ California |
Genetisk manipulerede immunoglobuliner
|
|
US5231167A
(en)
*
|
1989-09-08 |
1993-07-27 |
The Regents Of The University Of California |
Immunoglobulin-binding polypeptides
|
|
US5306812A
(en)
*
|
1989-09-08 |
1994-04-26 |
The Regents Of The University Of California |
Immunoglobulin-binding polypeptides
|
|
US5965695A
(en)
*
|
1990-05-15 |
1999-10-12 |
Chiron Corporation |
Modified peptide and peptide libraries with protease resistance, derivatives thereof and methods of producing and screening such
|
|
EP0592423B1
(en)
*
|
1990-08-06 |
2000-11-15 |
Chiron Corporation |
Methods for the identification of cytokine convertase inhibitors
|
|
WO1992011933A1
(en)
*
|
1991-01-04 |
1992-07-23 |
Perseptive Biosystems, Inc. |
Sulfonamide bonded hydrophilic coatings
|
|
US5665539A
(en)
*
|
1991-07-12 |
1997-09-09 |
The Regents Of The University Of California |
Immuno-polymerase chain reaction system for antigen detection
|
|
US5846717A
(en)
*
|
1996-01-24 |
1998-12-08 |
Third Wave Technologies, Inc. |
Detection of nucleic acid sequences by invader-directed cleavage
|
|
NZ246059A
(en)
*
|
1991-12-03 |
1995-08-28 |
Proteus Molecular Design |
Synthetic polypeptides with at least one antigenic site of a prion protein, methods of their use and manufacture, antibodies thereto, compositions and kits
|
|
US5424413A
(en)
*
|
1992-01-22 |
1995-06-13 |
Gen-Probe Incorporated |
Branched nucleic acid probes
|
|
TW327194B
(en)
*
|
1992-05-01 |
1998-02-21 |
American Cyanamid Co |
Novel amyloid precursor proteins and methods of using same
|
|
US5877278A
(en)
*
|
1992-09-24 |
1999-03-02 |
Chiron Corporation |
Synthesis of N-substituted oligomers
|
|
US5831005A
(en)
*
|
1992-09-24 |
1998-11-03 |
Chiron Corporation |
Synthesis of N-substituted oligomers
|
|
US5652138A
(en)
*
|
1992-09-30 |
1997-07-29 |
The Scripps Research Institute |
Human neutralizing monoclonal antibodies to human immunodeficiency virus
|
|
US5681697A
(en)
*
|
1993-12-08 |
1997-10-28 |
Chiron Corporation |
Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
|
|
US5792901A
(en)
*
|
1994-05-13 |
1998-08-11 |
The Regents Of The University Of California |
Detecting prions in a sample and prion preparation and transgenic animal used for same
|
|
US5908969A
(en)
*
|
1994-05-13 |
1999-06-01 |
The Regents Of The University Of California |
Method of detecting prions in a sample and transgenic animal used for same
|
|
US5565186A
(en)
*
|
1994-05-13 |
1996-10-15 |
The Regents Of The University Of California |
Method of detecting prions in a sample and transgenic animal used for same
|
|
US6168776B1
(en)
*
|
1994-07-19 |
2001-01-02 |
University Of Pittsburgh |
Alkyl, alkenyl and alkynyl Chrysamine G derivatives for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
|
|
US6376170B1
(en)
*
|
1994-10-03 |
2002-04-23 |
The Scripps Research Institute |
Ligand capture-directed selection of antibody
|
|
US5639581A
(en)
*
|
1994-10-24 |
1997-06-17 |
Fuji Xerox Co., Ltd. |
Charge transporting polymer, process for producing the same, and organic electronic device containing the same
|
|
US5854215A
(en)
*
|
1995-03-14 |
1998-12-29 |
Praecis Pharmaceuticals Incorporated |
Modulators of β-amyloid peptide aggregation
|
|
US5948763A
(en)
*
|
1995-06-07 |
1999-09-07 |
New York University |
Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits
|
|
NZ318689A
(en)
*
|
1995-09-14 |
1999-02-25 |
Univ California |
Prion antibodies specific for native prpsc and use for detecting human prpsc in a source
|
|
US5750361A
(en)
*
|
1995-11-02 |
1998-05-12 |
The Regents Of The University Of California |
Formation and use of prion protein (PRP) complexes
|
|
US5985557A
(en)
*
|
1996-01-24 |
1999-11-16 |
Third Wave Technologies, Inc. |
Invasive cleavage of nucleic acids
|
|
US6090606A
(en)
*
|
1996-01-24 |
2000-07-18 |
Third Wave Technologies, Inc. |
Cleavage agents
|
|
US6586193B2
(en)
*
|
1996-04-25 |
2003-07-01 |
Genicon Sciences Corporation |
Analyte assay using particulate labels
|
|
DE69725878T2
(de)
*
|
1996-08-13 |
2004-07-29 |
Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville |
Zusammensetzungen zur polynukleotidabgabe
|
|
US6172043B1
(en)
*
|
1997-01-10 |
2001-01-09 |
Massachusetts Institute Of Technology |
Treatments for neurotoxicity in Alzheimer's disease caused by β amyloid peptides
|
|
EP0861900A1
(en)
*
|
1997-02-21 |
1998-09-02 |
Erziehungsdirektion Of The Canton Zurich |
Immunological detection of prions
|
|
US5891641A
(en)
*
|
1997-02-21 |
1999-04-06 |
The Regents Of The University Of California |
Assay for disease related conformation of a protein
|
|
US20010001061A1
(en)
*
|
1997-02-21 |
2001-05-10 |
Prusiner Stanley B. |
Assay for disease related conformation of a protein
|
|
US7005295B1
(en)
*
|
1997-04-16 |
2006-02-28 |
Wyeth |
β-amyloid peptide-binding proteins and polynucleotides encoding the same
|
|
US6787319B2
(en)
*
|
1997-04-16 |
2004-09-07 |
American Home Products Corp. |
β-amyloid peptide-binding proteins and polynucleotides encoding the same
|
|
ES2329955T3
(es)
*
|
1997-04-28 |
2009-12-02 |
Novartis Vaccines And Diagnostics, Inc. |
Aparato para la sintesis de oligomeros, especialmente peptoides, con reciclado de reactivos.
|
|
US5962669A
(en)
*
|
1997-06-02 |
1999-10-05 |
The Regents Of The University Of California |
Nucleic acid encoding prion protein variant
|
|
US6214565B1
(en)
*
|
1998-10-09 |
2001-04-10 |
The Regents Of The University Of California |
Assay for disease related conformation of a protein and isolating same
|
|
ATE302269T1
(de)
*
|
1998-04-14 |
2005-09-15 |
Sugen Inc |
Ste20-verwandte proteinkinasen
|
|
US6211149B1
(en)
*
|
1998-08-03 |
2001-04-03 |
The United States Of America As Represented By The Department Of Health And Human Services |
Inhibitors of formation of protease resistant prion protein
|
|
GB2348203B
(en)
*
|
1998-11-04 |
2002-06-19 |
Imp College Innovations Ltd |
Solube beta-forms of prion proteins, methods of preparation and use
|
|
US6551843B1
(en)
*
|
1999-01-29 |
2003-04-22 |
Immunivest Corporation |
Methods for enhancing binding interactions between members of specific binding pairs
|
|
FR2801106B1
(fr)
*
|
1999-11-12 |
2007-10-05 |
Commissariat Energie Atomique |
Procede de diagnostic d'une esst provoquee par une souche d'atnc dans un echantillon biologique et son utilisation dans le diagnostic differentiel des differentes souches d'atnc
|
|
US6235483B1
(en)
*
|
2000-01-31 |
2001-05-22 |
Agilent Technologies, Inc. |
Methods and kits for indirect labeling of nucleic acids
|
|
HK1053972A1
(zh)
*
|
2000-02-16 |
2003-11-14 |
Northwestern University |
聚甘氨酸胺基取代的阳离子寡聚合物肺表面活性剂
|
|
AU2001251358A1
(en)
*
|
2000-04-05 |
2001-10-23 |
V.I. Technologies, Inc. |
Prion-binding ligands and methods of using same
|
|
US6511809B2
(en)
*
|
2000-06-13 |
2003-01-28 |
E. I. Du Pont De Nemours And Company |
Method for the detection of an analyte by means of a nucleic acid reporter
|
|
AU6887101A
(en)
*
|
2000-06-20 |
2002-01-02 |
Caprion Pharmaceuticals, Inc. |
Copolymers and methods of treating prion-related diseases
|
|
US6505025B2
(en)
*
|
2000-06-22 |
2003-01-07 |
Kyocera Corporation |
Color image forming apparatus and process
|
|
US6537548B1
(en)
*
|
2000-07-27 |
2003-03-25 |
The Regents Of The University Of California |
Antibodies specific for ungulate PrP
|
|
US20030092613A1
(en)
*
|
2000-08-14 |
2003-05-15 |
Lee Daniel H. S. |
Alpha7 nicotinic receptor peptides as ligands for beta amyloid peptides
|
|
US6721761B2
(en)
*
|
2000-12-20 |
2004-04-13 |
American Management Systems, Inc. |
System for assigning digital identifiers to telephone numbers and IP numbers
|
|
US7691639B2
(en)
*
|
2001-05-31 |
2010-04-06 |
Adlyfe, Inc. |
Misfolded protein sensor method
|
|
US20050026165A1
(en)
*
|
2001-05-31 |
2005-02-03 |
Cindy Orser |
Detection of conformationally altered proteins and prions
|
|
EP1572894B1
(en)
*
|
2001-11-21 |
2016-04-13 |
New York University |
Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid beta, prion protein, amylin, alpha synuclein, or polyglutamine repeats for induction of an immune response thereto
|
|
US20040052928A1
(en)
*
|
2002-09-06 |
2004-03-18 |
Ehud Gazit |
Peptides and methods using same for diagnosing and treating amyloid-associated diseases
|
|
EP1478931B2
(en)
*
|
2002-02-28 |
2018-11-07 |
Microsens Biophage Limited |
Binding of pathological forms of prion proteins
|
|
JP4421900B2
(ja)
*
|
2002-04-09 |
2010-02-24 |
ザ スクリップス リサーチ インスティテュート |
モチーフ・グラフトされたハイブリッドポリペプチドおよびその使用
|
|
US20040208919A1
(en)
*
|
2002-06-13 |
2004-10-21 |
Nicolau Yves C. |
Vaccination against prion diseases
|
|
DE10230141B4
(de)
*
|
2002-07-04 |
2004-07-15 |
Priontype Gmbh |
Verfahren und Kit zur Anreicherung und zum Nachweis von veränderten Prion-Proteinen (PrPSc)
|
|
EP1382971A1
(en)
*
|
2002-07-17 |
2004-01-21 |
Pepscan Systems B.V. |
Detection of prion disease
|
|
US20040072236A1
(en)
*
|
2002-09-27 |
2004-04-15 |
Neil Cashman |
PrPSc -interacting molecules and uses thereof
|
|
DK1953551T3
(da)
*
|
2002-12-03 |
2014-05-12 |
Univ North Carolina State |
Prion-proteinligander samt fremgangsmåder til anvendelse deraf
|
|
JP4783727B2
(ja)
*
|
2003-04-04 |
2011-09-28 |
パソゲン リムーバル アンド ダイアグノスティック テクノロジーズ インコーポレーテッド |
プリオンタンパク質結合物質と使用法
|
|
WO2004092197A2
(en)
*
|
2003-04-07 |
2004-10-28 |
The Regents Of The University Of California |
Amyloid-specific peptides and uses thereof
|
|
US20060035242A1
(en)
*
|
2004-08-13 |
2006-02-16 |
Michelitsch Melissa D |
Prion-specific peptide reagents
|
|
KR101166012B1
(ko)
*
|
2003-08-13 |
2012-07-23 |
노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 |
프리온-특이적 펩티드 시약
|
|
JP3910569B2
(ja)
*
|
2003-08-19 |
2007-04-25 |
独立行政法人科学技術振興機構 |
アミロイドβ蛋白質のアミロイド線維化を増幅するための試薬
|
|
US20060057671A1
(en)
*
|
2004-09-10 |
2006-03-16 |
Orser Cindy S |
Immobilized probes and methods of detecting conformationally altered prion proteins
|
|
US7482172B2
(en)
*
|
2005-09-19 |
2009-01-27 |
Ortho-Clinical Diagnostics, Inc. |
Peptides for discrimination of prions
|
|
WO2006076497A2
(en)
*
|
2005-01-13 |
2006-07-20 |
Novartis Vaccines And Diagnostics Inc. |
Osplation of pathogenic prions
|
|
CA2594840A1
(en)
*
|
2005-01-13 |
2006-07-20 |
Novartis Vaccines And Diagnostics Inc. |
Elisa assays using prion-specific peptide reagents
|
|
EP2383281A3
(en)
*
|
2005-09-09 |
2012-01-04 |
Novartis AG |
Prion-specific peptoid reagents
|
|
WO2008134034A1
(en)
*
|
2007-04-26 |
2008-11-06 |
Yale University |
Prion protein as a receptor for amyloid-beta oligomers
|