JP2011518828A5 - - Google Patents

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Publication number
JP2011518828A5
JP2011518828A5 JP2011506352A JP2011506352A JP2011518828A5 JP 2011518828 A5 JP2011518828 A5 JP 2011518828A5 JP 2011506352 A JP2011506352 A JP 2011506352A JP 2011506352 A JP2011506352 A JP 2011506352A JP 2011518828 A5 JP2011518828 A5 JP 2011518828A5
Authority
JP
Japan
Prior art keywords
pai
medicament
compound
combinations
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011506352A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011518828A (ja
Filing date
Publication date
Priority claimed from US12/421,456 external-priority patent/US20090202524A1/en
Application filed filed Critical
Publication of JP2011518828A publication Critical patent/JP2011518828A/ja
Publication of JP2011518828A5 publication Critical patent/JP2011518828A5/ja
Pending legal-status Critical Current

Links

JP2011506352A 2008-04-26 2009-04-10 眼球障害の処置のためのpai−1の発現および活性インヒビター Pending JP2011518828A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4817608P 2008-04-26 2008-04-26
US61/048,176 2008-04-26
US12/421,456 2009-04-09
US12/421,456 US20090202524A1 (en) 2007-10-31 2009-04-09 Pai-1 expression and activity inhibitors for the treatment of ocular disorders
PCT/US2009/040149 WO2009131850A2 (en) 2008-04-26 2009-04-10 Pai-1 expression and activity inhibitors for the treatment of ocular disorders

Publications (2)

Publication Number Publication Date
JP2011518828A JP2011518828A (ja) 2011-06-30
JP2011518828A5 true JP2011518828A5 (enExample) 2013-03-14

Family

ID=40810596

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011506352A Pending JP2011518828A (ja) 2008-04-26 2009-04-10 眼球障害の処置のためのpai−1の発現および活性インヒビター

Country Status (10)

Country Link
US (2) US20090202524A1 (enExample)
EP (1) EP2296647A2 (enExample)
JP (1) JP2011518828A (enExample)
KR (1) KR20100135953A (enExample)
CN (1) CN102046168A (enExample)
AR (1) AR071393A1 (enExample)
CL (1) CL2009000986A1 (enExample)
TW (1) TW200946113A (enExample)
UY (1) UY31786A1 (enExample)
WO (1) WO2009131850A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005105069A1 (en) * 2004-04-26 2005-11-10 Alcon, Inc. Statins for the treatment of ocular hypertension and glaucoma
US10946076B2 (en) * 2013-02-13 2021-03-16 The Research Foundation For The State University Of New York Glaucoma treatment
BR112016002753A2 (pt) 2013-08-13 2017-11-21 Sanofi Sa anticorpos contra o inibidor-1 de ativador de plasminogênio (pai-1) e usos dos mesmos
US10813920B2 (en) * 2013-11-14 2020-10-27 The Doshisha Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage
EP3381472A4 (en) 2015-12-24 2019-07-31 The Doshisha MEDICINAL PRODUCTS FOR THE TREATMENT OR PREVENTION OF DISTURBANCES CAUSED BY TGF SIGNALS AND USE THEREOF

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4214215A1 (de) * 1992-04-30 1993-11-04 Behringwerke Ag Verwendung von inhibitoren von plasminogenaktivatoren zur behandlung von entzuendungen
AU771635B2 (en) * 1999-01-05 2004-04-01 American National Red Cross, The Methods for treating conditions associated with the accumulation of excess extracellular matrix
US7074817B2 (en) * 2001-06-20 2006-07-11 Wyeth Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
EP1497420A4 (en) * 2002-04-30 2005-04-27 Alcon Inc AGENTS THAT REGULATE, RESTRICT OR MODULATE THE ACTIVITY AND / OR EXPRESSION OF BIND WEAVE GROWTH FACTOR (CTGF) AS UNIQUE MEDICAMENTS BOTH TO REDUCE EYESPRINTS AND TREAT GLACCOMPETOSIS RETINOPATHIES / OPTIC NEUROPATHIES
JP2007512347A (ja) * 2003-11-26 2007-05-17 デューク・ユニバーシティー 緑内障を予防するかまたは治療する方法
WO2005105069A1 (en) * 2004-04-26 2005-11-10 Alcon, Inc. Statins for the treatment of ocular hypertension and glaucoma
WO2006040839A1 (ja) * 2004-10-15 2006-04-20 Advanced Medicine Research Institute 眼疾患処置用点眼剤及びキット
US20060094753A1 (en) * 2004-10-29 2006-05-04 Alcon, Inc. Use of inhibitors of Jun N-terminal kinases for the treatment of glaucomatous retinopathy and ocular diseases
US7803824B2 (en) * 2004-10-29 2010-09-28 Alcon, Inc. Use of inhibitors of Jun N-terminal kinases to treat glaucoma
US8969295B2 (en) * 2006-04-14 2015-03-03 Massachusetts Institute Of Technology Identifying and modulating molecular pathways that mediate nervous system plasticity
US20080107644A1 (en) * 2006-10-31 2008-05-08 Alcon Manufacturing, Ltd. Pai-1 binding modulators for the treatment of ocular disorders

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