JP2011517666A5 - - Google Patents
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- Publication number
- JP2011517666A5 JP2011517666A5 JP2011500764A JP2011500764A JP2011517666A5 JP 2011517666 A5 JP2011517666 A5 JP 2011517666A5 JP 2011500764 A JP2011500764 A JP 2011500764A JP 2011500764 A JP2011500764 A JP 2011500764A JP 2011517666 A5 JP2011517666 A5 JP 2011517666A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrene
- peptide
- agent
- composition
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3863408P | 2008-03-21 | 2008-03-21 | |
| US61/038,634 | 2008-03-21 | ||
| PCT/US2009/000613 WO2009117041A2 (en) | 2008-03-21 | 2009-01-30 | Use of pyrene to carry peptides across the blood brain barrier |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011517666A JP2011517666A (ja) | 2011-06-16 |
| JP2011517666A5 true JP2011517666A5 (enExample) | 2013-04-11 |
Family
ID=40974375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011500764A Pending JP2011517666A (ja) | 2008-03-21 | 2009-01-30 | 血液脳関門を横断してペプチドを運搬するためのピレンの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090238754A1 (enExample) |
| EP (1) | EP2268314A2 (enExample) |
| JP (1) | JP2011517666A (enExample) |
| CN (1) | CN102014967A (enExample) |
| AU (1) | AU2009226161A1 (enExample) |
| CA (1) | CA2718860A1 (enExample) |
| MX (1) | MX2010010266A (enExample) |
| WO (1) | WO2009117041A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1395833B1 (en) | 2001-05-31 | 2013-02-27 | Adlyfe, Inc. | Misfolded protein sensor method |
| US20050026165A1 (en) | 2001-05-31 | 2005-02-03 | Cindy Orser | Detection of conformationally altered proteins and prions |
| EP2156181B1 (en) * | 2006-07-28 | 2015-11-04 | Adlyfe, Inc. | Peptide probes for diagnostics and therapeutics |
| US20090274621A1 (en) * | 2008-03-21 | 2009-11-05 | Adlyfe, Inc | Use of pyrene to carry non-peptide agents across the blood brain barrier |
| MX2011007916A (es) * | 2009-01-30 | 2011-11-18 | Adlyfe Inc | Péptidos conformacionalmente dinámicos. |
| US20140328762A1 (en) * | 2011-04-06 | 2014-11-06 | Yiyi Zhang | Fluorogenic Peptide Probes and Assays |
| EP2712425A2 (en) | 2011-04-27 | 2014-04-02 | Adlyfe, Inc. | Ocular detection of amyloid proteins |
| JP6144673B2 (ja) | 2011-06-03 | 2017-06-07 | オフィディオン インコーポレイティド | 血液脳関門を通過して輸送するための組成物及び方法 |
| PL230602B1 (pl) | 2013-04-04 | 2018-11-30 | Centrum Badan Molekularnych I Makromolekularnych Polskiej Akademii Nauk | Kwas (E)-3-arylo-3-oksoprop-1-enylo-2-fosfonowy i jego pochodne, sposob ich wytwarzania oraz ich zastosowanie |
| PL223918B1 (pl) | 2013-05-28 | 2016-11-30 | Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk | 3-Arylo-2-fosforylo podstawione 1-indanony i sposób ich wytwarzania |
| EP3634978A1 (en) | 2017-06-07 | 2020-04-15 | Adrx, Inc. | Tau aggregation inhibitors |
| EP3668886A2 (en) | 2017-08-18 | 2020-06-24 | Adrx, Inc. | Tau aggregation peptide inhibitors |
| CN110759974B (zh) * | 2018-07-25 | 2021-11-09 | 中国医学科学院药物研究所 | 一种磷脂-聚乙二醇-狂犬病毒衍生肽聚合物，其制备方法及应用 |
| US10369170B1 (en) | 2018-10-09 | 2019-08-06 | Carol J. Buck | Methods of treating basal cell carcinoma and glioblastoma |
| US10568907B1 (en) | 2018-10-09 | 2020-02-25 | Carol J. Buck | Methods of treating basal cell carcinoma and glioblastoma |
| IL293545A (en) | 2019-12-04 | 2022-08-01 | Univ Leland Stanford Junior | Enhancing blood-brain barrier drug transport by targeting endogenous regulators |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4822733A (en) * | 1985-05-28 | 1989-04-18 | Amoco Corporation | Lifetime-resolved assay procedures |
| US5260308A (en) * | 1991-11-06 | 1993-11-09 | Mayo Foundation For Medical Education And Research | Method to increase permeability of the blood-nerve/brain barriers to proteins |
| US5604198A (en) * | 1994-05-12 | 1997-02-18 | Poduslo; Joseph F. | Method to enhance permeability of the blood/brain blood/nerve barriers to therapeutic agents |
| US5670477A (en) * | 1995-04-20 | 1997-09-23 | Joseph F. Poduslo | Method to enhance permeability of the blood/brain blood/nerve bariers to therapeutic agents |
| EP1003539A4 (en) * | 1997-08-14 | 2002-09-11 | Univ California | AMYLOID beta-FLUORESCENT PEPTIDES AND USE THEREOF |
| US6761888B1 (en) * | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
| US20030162698A1 (en) * | 1999-01-27 | 2003-08-28 | Alphonse Galdes | Methods and compositions for treating dopaminergic and gaba-nergic disorders |
| AU2001249795A1 (en) * | 2000-04-04 | 2001-10-15 | Mayo Foundation For Medical Education And Research | Methods for detecting plaques in vivo |
| US7311893B2 (en) * | 2000-07-25 | 2007-12-25 | Neurochem (International) Limited | Amyloid targeting imaging agents and uses thereof |
| US7470420B2 (en) * | 2000-12-05 | 2008-12-30 | The Regents Of The University Of California | Optical determination of glucose utilizing boronic acid adducts |
| WO2002055547A2 (en) * | 2001-01-10 | 2002-07-18 | The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Health And Human Services | Sfrp and peptide motifs that interact with sfrp and methods of their use |
| GB0106953D0 (en) * | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| WO2002094191A2 (en) * | 2001-05-23 | 2002-11-28 | New York University | Detection of alzheimer's amyloid by magnetic resonance imaging |
| US20050026165A1 (en) * | 2001-05-31 | 2005-02-03 | Cindy Orser | Detection of conformationally altered proteins and prions |
| US7851593B2 (en) * | 2002-01-04 | 2010-12-14 | Becton, Dickinson And Company | Binding proteins as biosensors |
| JP2006510722A (ja) * | 2002-01-29 | 2006-03-30 | プロテミックス コーポレイション リミティド | 細胞障害性タンパク質コンフォーマーの抑制 |
| CA2542232A1 (en) * | 2003-06-09 | 2005-01-20 | Alnylam Pharmaceuticals, Inc. | Method for treating neurodegenerative disease by inhibiting alpha-synuclein |
| US20050009109A1 (en) * | 2003-07-08 | 2005-01-13 | Stanford University | Fluorophore compounds and their use in biological systems |
| US20060142227A1 (en) * | 2003-10-14 | 2006-06-29 | Itschak Lamensdorf | Amphiphylic peptide-PNA conjugates for the delivery of PNA through the blood brain barrier |
| WO2005076732A2 (en) * | 2004-02-17 | 2005-08-25 | Kernel Biopharma Inc. | Peptide-pna chimera targeting inducible nitric oxide synthase |
| WO2006076683A2 (en) * | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Isolation and detection of pathogenic prions |
| AU2006214463B2 (en) * | 2005-02-15 | 2012-08-30 | Presympto, Inc. | Method for detecting misfolded proteins and prions |
| US7951603B2 (en) * | 2005-03-31 | 2011-05-31 | The Noguchi Institute | Method of mass spectrometric analysis of saccharides with aldehyde groups using labels containing a pyrene ring and a hydrazide group |
| US7388747B2 (en) * | 2006-04-07 | 2008-06-17 | Inventec Corporation | Heat plate fixing structure |
| EP2156181B1 (en) * | 2006-07-28 | 2015-11-04 | Adlyfe, Inc. | Peptide probes for diagnostics and therapeutics |
| US20090274621A1 (en) * | 2008-03-21 | 2009-11-05 | Adlyfe, Inc | Use of pyrene to carry non-peptide agents across the blood brain barrier |
-
2009
- 2009-01-30 EP EP09722213A patent/EP2268314A2/en not_active Withdrawn
- 2009-01-30 CN CN2009801166660A patent/CN102014967A/zh active Pending
- 2009-01-30 US US12/363,254 patent/US20090238754A1/en not_active Abandoned
- 2009-01-30 JP JP2011500764A patent/JP2011517666A/ja active Pending
- 2009-01-30 CA CA2718860A patent/CA2718860A1/en not_active Abandoned
- 2009-01-30 AU AU2009226161A patent/AU2009226161A1/en not_active Abandoned
- 2009-01-30 WO PCT/US2009/000613 patent/WO2009117041A2/en not_active Ceased
- 2009-01-30 MX MX2010010266A patent/MX2010010266A/es active IP Right Grant
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