JP2011517312A5 - - Google Patents

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Publication number
JP2011517312A5
JP2011517312A5 JP2010537023A JP2010537023A JP2011517312A5 JP 2011517312 A5 JP2011517312 A5 JP 2011517312A5 JP 2010537023 A JP2010537023 A JP 2010537023A JP 2010537023 A JP2010537023 A JP 2010537023A JP 2011517312 A5 JP2011517312 A5 JP 2011517312A5
Authority
JP
Japan
Prior art keywords
binding affinity
vmat
compounds
carbinol compounds
fluoroalkyltetrabenazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010537023A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011517312A (ja
JP5597835B2 (ja
Filing date
Publication date
Priority claimed from US11/952,340 external-priority patent/US7919622B2/en
Priority claimed from US11/952,325 external-priority patent/US8013161B1/en
Application filed filed Critical
Priority claimed from PCT/US2008/085304 external-priority patent/WO2009073677A1/en
Publication of JP2011517312A publication Critical patent/JP2011517312A/ja
Publication of JP2011517312A5 publication Critical patent/JP2011517312A5/ja
Application granted granted Critical
Publication of JP5597835B2 publication Critical patent/JP5597835B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010537023A 2007-12-07 2008-12-03 イメージング剤及びプローブとしてのフルオロアルキルテトラベナジンカルビノール化合物 Expired - Fee Related JP5597835B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/952,325 2007-12-07
US11/952,340 US7919622B2 (en) 2007-12-07 2007-12-07 Intermediates for fluorinated tetrabenazine carbinol compounds imaging agents and probes
US11/952,325 US8013161B1 (en) 2007-12-07 2007-12-07 Fluoroalkyl tetrabenazine carbinol compounds as imaging agents and probes
US11/952,340 2007-12-07
PCT/US2008/085304 WO2009073677A1 (en) 2007-12-07 2008-12-03 Fluoroalkyl tetrabenazine carbinol compounds as imaging agents and probes

Publications (3)

Publication Number Publication Date
JP2011517312A JP2011517312A (ja) 2011-06-02
JP2011517312A5 true JP2011517312A5 (enExample) 2014-01-09
JP5597835B2 JP5597835B2 (ja) 2014-10-01

Family

ID=40342752

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010537023A Expired - Fee Related JP5597835B2 (ja) 2007-12-07 2008-12-03 イメージング剤及びプローブとしてのフルオロアルキルテトラベナジンカルビノール化合物

Country Status (5)

Country Link
EP (1) EP2220085B1 (enExample)
JP (1) JP5597835B2 (enExample)
CN (1) CN101889013B (enExample)
ES (1) ES2451661T3 (enExample)
WO (1) WO2009073677A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201705303D0 (en) * 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705305D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705302D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705304D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705306D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201808464D0 (en) 2018-05-23 2018-07-11 Adeptio Pharmaceuticals Ltd Pharmaceutical compounds for use in treating huntington's disease
CN114288419B (zh) * 2021-12-30 2023-08-18 中山大学附属第八医院(深圳福田) 一种利福平纳米递药系统的制备及其在防治帕金森病方面的应用
WO2026050236A1 (en) 2024-08-27 2026-03-05 Neurocrine Biosciences, Inc. Muscarinic receptor agonist in combination with a vesicular monoamine transporter 2 inhibitor, for use in the treatment of a neurological or psychiatric disorder

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds

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