HUS2300024I1 - IX-es faktor polipeptid mutáns, alkalmazásai és eljárás elõállítására - Google Patents

IX-es faktor polipeptid mutáns, alkalmazásai és eljárás elõállítására

Info

Publication number
HUS2300024I1
HUS2300024I1 HUS2300024C HUS2300024C HUS2300024I1 HU S2300024 I1 HUS2300024 I1 HU S2300024I1 HU S2300024 C HUS2300024 C HU S2300024C HU S2300024 C HUS2300024 C HU S2300024C HU S2300024 I1 HUS2300024 I1 HU S2300024I1
Authority
HU
Hungary
Prior art keywords
factor
production
polypeptide mutant
mutant
polypeptide
Prior art date
Application number
HUS2300024C
Other languages
English (en)
Original Assignee
Uniqure Biopharma B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41397565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUS2300024(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from ITBO2008A000564A external-priority patent/IT1394177B1/it
Priority claimed from ITBO2009A000275A external-priority patent/IT1395980B1/it
Application filed by Uniqure Biopharma B V filed Critical Uniqure Biopharma B V
Publication of HUS2300024I1 publication Critical patent/HUS2300024I1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HUS2300024C 2008-09-15 2023-07-25 IX-es faktor polipeptid mutáns, alkalmazásai és eljárás elõállítására HUS2300024I1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITBO2008A000564A IT1394177B1 (it) 2008-09-15 2008-09-15 Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzione
ITBO2009A000275A IT1395980B1 (it) 2009-05-06 2009-05-06 Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzione
EP19174517.3A EP3581650B1 (en) 2008-09-15 2009-09-15 Factor ix polypeptide mutant, its uses and a method for its production

Publications (1)

Publication Number Publication Date
HUS2300024I1 true HUS2300024I1 (hu) 2023-08-28

Family

ID=41397565

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE19174517A HUE061345T2 (hu) 2008-09-15 2009-09-15 IX-es faktor polipeptid mutáns, alkalmazásai és eljárás elõállítására
HUS2300024C HUS2300024I1 (hu) 2008-09-15 2023-07-25 IX-es faktor polipeptid mutáns, alkalmazásai és eljárás elõállítására

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE19174517A HUE061345T2 (hu) 2008-09-15 2009-09-15 IX-es faktor polipeptid mutáns, alkalmazásai és eljárás elõállítására

Country Status (17)

Country Link
US (11) US9249405B2 (hu)
EP (5) EP3581650B1 (hu)
CA (1) CA2737094C (hu)
CY (2) CY1125885T1 (hu)
DK (2) DK2337849T3 (hu)
ES (2) ES2687038T3 (hu)
FI (2) FI3581650T3 (hu)
FR (1) FR23C1028I1 (hu)
HK (1) HK1244507A1 (hu)
HR (2) HRP20230259T1 (hu)
HU (2) HUE061345T2 (hu)
LT (2) LT3581650T (hu)
PL (2) PL3581650T3 (hu)
PT (1) PT3581650T (hu)
SI (1) SI3581650T1 (hu)
TR (1) TR201813067T4 (hu)
WO (1) WO2010029178A1 (hu)

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TWI557135B (zh) 2010-11-03 2016-11-11 介控生化科技公司 經修飾之第九因子多胜肽及其用途
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ES2959747T3 (es) 2013-02-15 2024-02-28 Bioverativ Therapeutics Inc Gen del factor VIII optimizado
EP3160478A4 (en) 2014-06-30 2018-05-16 Bioverativ Therapeutics Inc. Optimized factor ix gene
GB201420139D0 (en) 2014-11-12 2014-12-24 Ucl Business Plc Factor IX gene therapy
JP6831779B2 (ja) 2015-06-23 2021-02-17 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアＴｈｅ Ｃｈｉｌｄｒｅｎ’Ｓ Ｈｏｓｐｉｔａｌ Ｏｆ Ｐｈｉｌａｄｅｌｐｈｉａ 修飾された第ｉｘ因子、並びに、細胞、器官及び組織への遺伝子導入のための組成物、方法及び使用
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US20200069819A1 (en) 2018-05-14 2020-03-05 Biomarin Pharmaceutical Inc. Stable expression of aav vectors in juvenile subjects
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US10842885B2 (en) 2018-08-20 2020-11-24 Ucl Business Ltd Factor IX encoding nucleotides
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JP6831779B2 (ja) 2015-06-23 2021-02-17 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアＴｈｅ Ｃｈｉｌｄｒｅｎ’Ｓ Ｈｏｓｐｉｔａｌ Ｏｆ Ｐｈｉｌａｄｅｌｐｈｉａ 修飾された第ｉｘ因子、並びに、細胞、器官及び組織への遺伝子導入のための組成物、方法及び使用
EA201890423A1 (ru) 2015-08-03 2018-07-31 Биовератив Терапьютикс Инк. Слитые белки фактора ix, способы их получения и применения

Also Published As

Publication number Publication date
TR201813067T4 (tr) 2018-09-21
EP2337849B1 (en) 2018-06-13
US20170355973A1 (en) 2017-12-14
LTPA2023521I1 (hu) 2023-08-25
FI3581650T3 (fi) 2023-03-23
EP3581650A2 (en) 2019-12-18
DK2337849T3 (en) 2018-10-01
SI3581650T1 (sl) 2023-06-30
US20180258413A1 (en) 2018-09-13
DK3581650T3 (da) 2023-03-13
EP3581650A3 (en) 2020-03-25
US9249405B2 (en) 2016-02-02
EP4032979A1 (en) 2022-07-27
HK1244507A1 (zh) 2018-08-10
ES2940323T3 (es) 2023-05-05
PL3581650T3 (pl) 2023-05-22
EP3252157A1 (en) 2017-12-06
US20200190498A1 (en) 2020-06-18
US20110244550A1 (en) 2011-10-06
EP4219547A3 (en) 2023-10-18
HRP20181442T1 (hr) 2018-12-14
CA2737094C (en) 2018-02-20
CY2023016I2 (el) 2024-02-16
CA2737094A1 (en) 2010-03-18
EP4032979C0 (en) 2024-05-01
PT3581650T (pt) 2023-03-08
US20200199564A1 (en) 2020-06-25
CY2023016I1 (el) 2024-02-16
FR23C1028I1 (fr) 2023-10-06
US20210238573A1 (en) 2021-08-05
US20220002702A1 (en) 2022-01-06
US20160122740A1 (en) 2016-05-05
EP4219547A2 (en) 2023-08-02
CA2737094F (en) 2010-03-18
US20220090042A1 (en) 2022-03-24
CY1125885T1 (el) 2024-02-16
EP3581650B1 (en) 2022-12-28
ES2687038T3 (es) 2018-10-23
HUE061345T2 (hu) 2023-06-28
US20210214704A1 (en) 2021-07-15
LT3581650T (lt) 2023-05-10
FIC20230026I1 (fi) 2023-07-25
WO2010029178A1 (en) 2010-03-18
US20200231958A1 (en) 2020-07-23
EP4032979B1 (en) 2024-05-01
HRP20230259T1 (hr) 2023-04-28
US9982248B2 (en) 2018-05-29
PL2337849T3 (pl) 2018-11-30
EP2337849A1 (en) 2011-06-29
US10465180B2 (en) 2019-11-05

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