IT1395980B1 - Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzione - Google Patents
Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzioneInfo
- Publication number
- IT1395980B1 IT1395980B1 ITBO2009A000275A ITBO20090275A IT1395980B1 IT 1395980 B1 IT1395980 B1 IT 1395980B1 IT BO2009A000275 A ITBO2009A000275 A IT BO2009A000275A IT BO20090275 A ITBO20090275 A IT BO20090275A IT 1395980 B1 IT1395980 B1 IT 1395980B1
- Authority
- IT
- Italy
- Prior art keywords
- modified
- production
- polypeptide factor
- polypeptide
- factor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/644—Coagulation factor IXa (3.4.21.22)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (40)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITBO2009A000275A IT1395980B1 (it) | 2009-05-06 | 2009-05-06 | Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzione |
TR2018/13067T TR201813067T4 (tr) | 2008-09-15 | 2009-09-15 | Faktör IX polipeptit mutantı, bunun kullanımları ve bunu üretmeye yönelik bir yöntem. |
LTEP19174517.3T LT3581650T (lt) | 2008-09-15 | 2009-09-15 | Faktoriaus ix polipeptido mutantas, jo panaudojimas ir jo gamybos būdas |
CA2737094A CA2737094C (en) | 2008-09-15 | 2009-09-15 | Factor ix polypeptide mutant, its uses and a method for its production |
PT191745173T PT3581650T (pt) | 2008-09-15 | 2009-09-15 | Mutante de polipéptido de fator ix, as suas utilizações e um método para a sua produção |
FIEP19174517.3T FI3581650T3 (fi) | 2008-09-15 | 2009-09-15 | IX-tekijän polypeptidimutantti, sen käyttöjä ja menetelmä sen valmistamiseksi |
EP09748260.8A EP2337849B1 (en) | 2008-09-15 | 2009-09-15 | Factor ix polypeptide mutant, its uses and a method for its production |
HRP20230259TT HRP20230259T1 (hr) | 2008-09-15 | 2009-09-15 | Mutant polipeptida faktora ix, njegove primjene i postupak za njegovu proizvodnju |
ES09748260.8T ES2687038T3 (es) | 2008-09-15 | 2009-09-15 | Mutante de polipéptido factor IX, sus usos y un método para su producción |
DK09748260.8T DK2337849T3 (en) | 2008-09-15 | 2009-09-15 | FACTOR IX POLYPEPTIME MUTANT, APPLICATIONS THEREOF AND METHOD OF PRODUCING THEREOF |
EP19174517.3A EP3581650B1 (en) | 2008-09-15 | 2009-09-15 | Factor ix polypeptide mutant, its uses and a method for its production |
PL09748260T PL2337849T3 (pl) | 2008-09-15 | 2009-09-15 | Zmutowany polipeptyd czynnika ix, jego zastosowania i sposób jego otrzymywania |
DK19174517.3T DK3581650T3 (da) | 2008-09-15 | 2009-09-15 | Faktor ix polypeptidmutant, anvendelse deraf og en fremgangsmåde til fremstilling deraf |
SI200932179T SI3581650T1 (sl) | 2008-09-15 | 2009-09-15 | Polipeptidni mutant faktorja IX, njegova uporaba in metoda za njegovo proizvodnjo |
EP22214327.3A EP4219547A3 (en) | 2008-09-15 | 2009-09-15 | Factor ix polypeptide mutant, its uses and a method for its production |
US13/063,898 US9249405B2 (en) | 2008-09-15 | 2009-09-15 | Factor IX polypeptide mutant, its uses and a method for its production |
PCT/EP2009/061935 WO2010029178A1 (en) | 2008-09-15 | 2009-09-15 | Factor ix polypeptide mutant, its uses and a method for its production |
HUE19174517A HUE061345T2 (hu) | 2008-09-15 | 2009-09-15 | IX-es faktor polipeptid mutáns, alkalmazásai és eljárás elõállítására |
EP21200005.3A EP4032979B1 (en) | 2008-09-15 | 2009-09-15 | Factor ix polypeptide mutant, its uses and a method for its production |
EP17175191.0A EP3252157A1 (en) | 2008-09-15 | 2009-09-15 | Factor ix polypeptide mutant, its uses and a method for its production |
PL19174517.3T PL3581650T3 (pl) | 2008-09-15 | 2009-09-15 | Zmutowany polipeptyd czynnika ix, jego zastosowania i sposób jego wytwarzania |
ES19174517T ES2940323T3 (es) | 2008-09-15 | 2009-09-15 | Mutante de polipéptido factor IX, sus usos y un método para su producción |
US14/981,981 US20160122740A1 (en) | 2008-09-15 | 2015-12-29 | Factor ix polypeptide mutant, its uses and method for its production |
US15/650,070 US9982248B2 (en) | 2008-09-15 | 2017-07-14 | Factor IX polypeptide mutant, its uses and method for its production |
HK18103924.5A HK1244507A1 (zh) | 2008-09-15 | 2018-03-21 | 因子ix多肽突變體、其用途及生產方法 |
US15/989,665 US10465180B2 (en) | 2008-09-15 | 2018-05-25 | Factor IX polypeptide mutant, its uses and method for its production |
HRP20181442TT HRP20181442T1 (hr) | 2008-09-15 | 2018-09-10 | Mutant polipeptida faktora ix, njegove koristi i postupak njegove proizvodnje |
US16/589,851 US20200231958A1 (en) | 2008-09-15 | 2019-10-01 | Factor ix polypeptide mutant, its uses and a method for its production |
US16/707,414 US20200190498A1 (en) | 2008-09-15 | 2019-12-09 | Factor ix polypeptide mutant, its uses and a method for its production |
US16/787,456 US20200199564A1 (en) | 2008-09-15 | 2020-02-11 | Factor ix polypeptide mutant, its uses and a method for its production |
US17/213,848 US20210238573A1 (en) | 2008-09-15 | 2021-03-26 | Factor ix polypeptide mutant, its uses and a method for its production |
US17/213,897 US20210214704A1 (en) | 2008-09-15 | 2021-03-26 | Factor ix polypeptide mutant, its uses and a method for its production |
US17/447,372 US20220002702A1 (en) | 2008-09-15 | 2021-09-10 | Factor ix polypeptide mutant, its uses and a method for its production |
US17/643,326 US20220090042A1 (en) | 2008-09-15 | 2021-12-08 | Factor ix polypeptide mutant, its uses and a method for its production |
CY20231100138T CY1125885T1 (el) | 2008-09-15 | 2023-03-14 | Τροποποιημενο πολυπεπτιδιο παραγοντα ix, οι χρησεις του και μια μεθοδος για την παραγωγη του |
FIC20230026C FIC20230026I1 (fi) | 2008-09-15 | 2023-07-25 | Etranakogeenidetsaparvoveekki (adenoassosioitu virusvektori, joka sisältää ihmisen hyytymistekijä IX:n geenin koodonioptimoitua Padua-johdannaista B-hemofilian hoitoon) |
HUS2300024C HUS2300024I1 (hu) | 2008-09-15 | 2023-07-25 | IX-es faktor polipeptid mutáns, alkalmazásai és eljárás elõállítására |
FR23C1028C FR23C1028I1 (fr) | 2008-09-15 | 2023-07-26 | Mutant de polypeptide du facteur ix, ses utilisations et son procédé de production |
CY2023016C CY2023016I2 (el) | 2008-09-15 | 2023-07-27 | Τροποποιημενο πολυπεπτιδιο παραγοντα ix, οι χρησεις του και μια μεθοδος για την παραγωγη του |
LTPA2023521C LTPA2023521I1 (it) | 2008-09-15 | 2023-07-27 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITBO2009A000275A IT1395980B1 (it) | 2009-05-06 | 2009-05-06 | Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzione |
Publications (2)
Publication Number | Publication Date |
---|---|
ITBO20090275A1 ITBO20090275A1 (it) | 2010-11-07 |
IT1395980B1 true IT1395980B1 (it) | 2012-11-09 |
Family
ID=41277414
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITBO2009A000275A IT1395980B1 (it) | 2008-09-15 | 2009-05-06 | Polipeptide fattore ix modificato, sue utilizzazioni e metodo per la sua produzione |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1395980B1 (it) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6531298B2 (en) * | 1997-07-21 | 2003-03-11 | The University Of North Carolina At Chapel Hill | Factor IX antihemophilic factor with increased clotting activity |
EP2423305A1 (en) * | 2006-06-19 | 2012-02-29 | Catalyst Biosciences, Inc. | Modified coagulation factor IX polypeptides and use thereof for treatment |
US7700734B2 (en) * | 2007-01-09 | 2010-04-20 | Shu-Wha Lin | Recombinant human factor IX and use thereof |
US20080214462A1 (en) * | 2007-02-01 | 2008-09-04 | Baxter International Inc. | FIX-Mutant Proteins for Hemophilia B Treatment |
-
2009
- 2009-05-06 IT ITBO2009A000275A patent/IT1395980B1/it active
Also Published As
Publication number | Publication date |
---|---|
ITBO20090275A1 (it) | 2010-11-07 |
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