JP2011515441A5 - - Google Patents

Download PDF

Info

Publication number
JP2011515441A5
JP2011515441A5 JP2011501210A JP2011501210A JP2011515441A5 JP 2011515441 A5 JP2011515441 A5 JP 2011515441A5 JP 2011501210 A JP2011501210 A JP 2011501210A JP 2011501210 A JP2011501210 A JP 2011501210A JP 2011515441 A5 JP2011515441 A5 JP 2011515441A5
Authority
JP
Japan
Prior art keywords
group
formula
compound
hydrogen atom
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011501210A
Other languages
English (en)
Japanese (ja)
Other versions
JP5725299B2 (ja
JP2011515441A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2009/053483 external-priority patent/WO2009118327A1/en
Publication of JP2011515441A publication Critical patent/JP2011515441A/ja
Publication of JP2011515441A5 publication Critical patent/JP2011515441A5/ja
Application granted granted Critical
Publication of JP5725299B2 publication Critical patent/JP5725299B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011501210A 2008-03-26 2009-03-25 1,4−ナフトキノン誘導体およびその治療用途 Active JP5725299B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08290278.4 2008-03-26
EP08290278 2008-03-26
PCT/EP2009/053483 WO2009118327A1 (en) 2008-03-26 2009-03-25 1,4-naphthoquinone derivatives and therapeutic use thereof

Publications (3)

Publication Number Publication Date
JP2011515441A JP2011515441A (ja) 2011-05-19
JP2011515441A5 true JP2011515441A5 (https=) 2012-04-12
JP5725299B2 JP5725299B2 (ja) 2015-05-27

Family

ID=39529700

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011501210A Active JP5725299B2 (ja) 2008-03-26 2009-03-25 1,4−ナフトキノン誘導体およびその治療用途

Country Status (7)

Country Link
US (1) US9090549B2 (https=)
EP (1) EP2257515B1 (https=)
JP (1) JP5725299B2 (https=)
CN (2) CN102015607A (https=)
AP (1) AP2660A (https=)
ES (1) ES2637496T3 (https=)
WO (1) WO2009118327A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2505583A1 (en) 2011-03-29 2012-10-03 Centre National de la Recherche Scientifique Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
US20150224066A1 (en) * 2012-09-25 2015-08-13 University Of Iowa Research Foundation Antimicrobial compositions and methods of use
CN110582480B (zh) 2017-04-21 2023-11-10 塔斯马尼亚大学 治疗化合物和方法
EP4053096A1 (en) * 2021-03-05 2022-09-07 Centre national de la recherche scientifique Photoredox radical benzylation process
CN113264818B (zh) * 2021-05-25 2022-07-05 湖北工业大学 一种银催化醌类化合物与醇类的碳碳交叉偶联反应的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2398418A (en) * 1943-08-27 1946-04-16 Louis F Fieser Introduction of organic radicals into quinones
ATE74269T1 (de) * 1987-07-29 1992-04-15 Takeda Chemical Industries Ltd Zellproliferationsinhibitor.
US5244917A (en) * 1992-06-02 1993-09-14 The Dupont Merck Pharmaceutical Company Substituted naphthofurans as anti-inflammatory agents
ES2255251T3 (es) * 1998-03-20 2006-06-16 Daiichi Asubio Pharma Co., Ltd. Inhibidores de nf-kb que contienen derivados de benzoquinona.
US20040022787A1 (en) * 2000-07-03 2004-02-05 Robert Cohen Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID
JP4780371B2 (ja) 2003-06-27 2011-09-28 武田薬品工業株式会社 光学活性化合物の製造法
AU2003265967A1 (en) * 2003-09-05 2005-04-21 Georgia State University Research Foundation, Inc Novel amidine compounds for treating microbial infections
US7517893B2 (en) * 2005-05-20 2009-04-14 The University Of North Carolina At Chapel Hill Bichalcophenes and their prodrugs as antiprotozoal agents

Similar Documents

Publication Publication Date Title
Murugesan et al. Discovery and structure–activity relationships of Pyrrolone Antimalarials
CN105906617B (zh) Hec1活性调节剂及其方法
JP6511430B2 (ja) がんの治療のための化合物および組成物
Singh et al. Antimalarial pyrido [1, 2-a] benzimidazoles: lead optimization, parasite life cycle stage profile, mechanistic evaluation, killing kinetics, and in vivo oral efficacy in a mouse model
JP2008517983A5 (https=)
JP2004516314A5 (https=)
JP2002513793A5 (https=)
CN1414953A (zh) 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和5-羟色胺重摄取的用途
JP2011515441A5 (https=)
Orozco et al. Recent synthetic efforts in the preparation of 2-(3, 4)-alkenyl (aryl) quinoline molecules towards anti-kinetoplastid agents
HUP0301932A2 (hu) IL-1béta és TNF-a inhibitor benzofenon származékok, ezeket tartalmazó gyógyszerkészítmények és ezek alkalmazása gyógyszerkészítmények elżállítására
JP2002030084A5 (https=)
JP6149129B2 (ja) 早期老化、特には早老症を治療する為に有用な化合物
JP2005538974A5 (https=)
CN102532150A (zh) 一种烷氧基二苯并吖庚因类化合物、其制备方法及医药用途
JP2003513066A5 (https=)
CN101443008A (zh) 芳基-和杂芳基-取代的四氢异喹啉和其阻止去甲肾上腺素,3-羟酪胺和5-羟色胺的再吸收的用途
RU2010154417A (ru) Комбинация частичного агониста никотиновых рецепторов и ингибитора ацетилхолинетеразы, содержащая ее фармацетическая композиция, и ее применение в лечении когнитивных расстройств
JP2009519227A5 (https=)
Ismail et al. An Exploration of the Structure-activity Relationships of 4− Aminoquinolines: Novel Antimalarials with Activity In-vivo
CN111925368A (zh) 嘧啶酮类衍生物及其制备方法和在抗结核杆菌感染中的应用
Deng et al. Synthesis of 3-Functionalized 4-Quinolones from Readily Available Anthranilic Acids
JP2007529471A5 (https=)
EP0785924B1 (fr) Bis-2-aminopyridines, leur procede de preparation et leurs applications contre les parasitoses
Kaliraj et al. Design, synthesis of Dioxopiperidinamide derivatives by amide coupling reaction and study of their biological activity