JP2011515329A - フルオロメチル１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテル（セボフルラン）の精製方法 - Google Patents

フルオロメチル１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテル（セボフルラン）の精製方法 Download PDF

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Publication number
JP2011515329A
JP2011515329A JP2010540655A JP2010540655A JP2011515329A JP 2011515329 A JP2011515329 A JP 2011515329A JP 2010540655 A JP2010540655 A JP 2010540655A JP 2010540655 A JP2010540655 A JP 2010540655A JP 2011515329 A JP2011515329 A JP 2011515329A
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Japan
Prior art keywords
sevoflurane
hfip
crude
ppm
purified
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Pending
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JP2010540655A
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English (en)
Japanese (ja)
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JP2011515329A5 (enExample
Inventor
バリー ジョーンズ
ジョエル スウィンソン
ポール マゼル
Original Assignee
ハロカーボン プロダクツ コーポレーション
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Application filed by ハロカーボン プロダクツ コーポレーション filed Critical ハロカーボン プロダクツ コーポレーション
Publication of JP2011515329A publication Critical patent/JP2011515329A/ja
Publication of JP2011515329A5 publication Critical patent/JP2011515329A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/34—Separation; Purification; Stabilisation; Use of additives
    • C07C41/38—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/10—Process efficiency

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2010540655A 2007-12-27 2008-12-22 フルオロメチル１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテル（セボフルラン）の精製方法 Pending JP2011515329A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/965,137 US7732647B2 (en) 2007-12-27 2007-12-27 Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)
US11/965,137 2007-12-27
PCT/US2008/013981 WO2009085247A2 (en) 2007-12-27 2008-12-22 Process for the purification of fluromethyl 1,1,1,3,3,3,-hexafluoroisopropyl ether (sevoflurane)

Publications (2)

Publication Number Publication Date
JP2011515329A true JP2011515329A (ja) 2011-05-19
JP2011515329A5 JP2011515329A5 (enExample) 2012-02-16

Family

ID=40799288

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010540655A Pending JP2011515329A (ja) 2007-12-27 2008-12-22 フルオロメチル１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテル（セボフルラン）の精製方法

Country Status (9)

Country Link
US (1) US7732647B2 (enExample)
EP (1) EP2231574B1 (enExample)
JP (1) JP2011515329A (enExample)
KR (1) KR20100103643A (enExample)
CN (1) CN102066300B (enExample)
BR (1) BRPI0821708A2 (enExample)
CA (1) CA2710218C (enExample)
HU (1) HUE028167T2 (enExample)
WO (1) WO2009085247A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5360208B2 (ja) * 2009-06-15 2013-12-04 ダイキン工業株式会社 高純度含フッ素エーテルの製造方法
JP2015143359A (ja) * 2013-12-26 2015-08-06 セントラル硝子株式会社 共沸混合物様の組成物、熱伝達組成物、洗浄剤、高温ヒートポンプ装置、冷凍サイクルシステム及び熱伝達方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8987524B2 (en) 2009-08-10 2015-03-24 Solvay Fluor Gmbh Process for the manufacture of Sevoflurane
CN105664883B (zh) * 2009-09-01 2020-09-08 蓝区技术有限公司 用于气体处理的系统和方法
EP2673256B1 (en) 2011-02-10 2015-04-08 Solvay SA Process for the manufacture of fluoromethoxymalonic acid derivatives
EP2626341A1 (en) 2012-02-10 2013-08-14 Solvay Sa Manufacture of hexafluoroisopropanol
CN105523903B (zh) * 2016-01-30 2017-07-18 华东医药（西安）博华制药有限公司 一种七氟烷的纯化方法
US10035745B1 (en) 2016-07-30 2018-07-31 Baxter International Inc. Methods of purifying crude sevoflurane
JP6299905B1 (ja) * 2017-02-06 2018-03-28 セントラル硝子株式会社 セボフルランの製造方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07280790A (ja) * 1994-04-08 1995-10-27 Central Glass Co Ltd フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルのガスクロマトグラフ分析
JPH11246459A (ja) * 1998-03-03 1999-09-14 Central Glass Co Ltd フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法
JP2003530323A (ja) * 2000-03-16 2003-10-14 ヘイロウカーボン プロダクツ コーポレイション フルオロメチル２，２，２−トリフルオロ−１−（トリフルオロメチル）エチルエーテルの生産
WO2007019161A2 (en) * 2005-08-04 2007-02-15 Halocarbon Products Corporation Purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250334A (en) 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
GB9600072D0 (en) 1996-01-04 1996-03-06 Ici Plc Process for the production of fluoromethylhexafluoroisopropylether
US6100434A (en) 1999-03-26 2000-08-08 Abbott Laboratories Method for synthesizing sevoflurane and an intermediate thereof
GB0031310D0 (en) 2000-12-21 2001-01-31 Ici Plc Process for the purification of fluoromethyl hexafluoroisopropyl ether
JP2007518078A (ja) * 2004-01-05 2007-07-05 ヘイロウカーボン プロダクツ コーポレイション プロセス中及び完成セボフルランの両方の分析のクロマトグラフ法
WO2007001916A2 (en) * 2005-06-27 2007-01-04 Dow Global Technologies, Inc. Window envelopes with optical character readable window film patches

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07280790A (ja) * 1994-04-08 1995-10-27 Central Glass Co Ltd フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルのガスクロマトグラフ分析
JPH11246459A (ja) * 1998-03-03 1999-09-14 Central Glass Co Ltd フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法
JP2003530323A (ja) * 2000-03-16 2003-10-14 ヘイロウカーボン プロダクツ コーポレイション フルオロメチル２，２，２−トリフルオロ−１−（トリフルオロメチル）エチルエーテルの生産
WO2007019161A2 (en) * 2005-08-04 2007-02-15 Halocarbon Products Corporation Purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)
JP2009503095A (ja) * 2005-08-04 2009-01-29 ヘイロウカーボン プロダクツ コーポレイション フルオロメチル１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテル（セボフルラン）の精製方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5360208B2 (ja) * 2009-06-15 2013-12-04 ダイキン工業株式会社 高純度含フッ素エーテルの製造方法
JP2015143359A (ja) * 2013-12-26 2015-08-06 セントラル硝子株式会社 共沸混合物様の組成物、熱伝達組成物、洗浄剤、高温ヒートポンプ装置、冷凍サイクルシステム及び熱伝達方法

Also Published As

Publication number Publication date
WO2009085247A2 (en) 2009-07-09
WO2009085247A3 (en) 2012-10-04
CA2710218C (en) 2016-06-07
US20090171128A1 (en) 2009-07-02
US7732647B2 (en) 2010-06-08
BRPI0821708A2 (pt) 2015-06-16
EP2231574A2 (en) 2010-09-29
CN102066300B (zh) 2013-12-25
HUE028167T2 (en) 2016-12-28
EP2231574A4 (en) 2014-03-05
CN102066300A (zh) 2011-05-18
EP2231574B1 (en) 2015-10-07
KR20100103643A (ko) 2010-09-27
WO2009085247A8 (en) 2015-08-27
CA2710218A1 (en) 2009-07-09

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