JP2011512871A5 - - Google Patents

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JP2011512871A5
JP2011512871A5 JP2010550699A JP2010550699A JP2011512871A5 JP 2011512871 A5 JP2011512871 A5 JP 2011512871A5 JP 2010550699 A JP2010550699 A JP 2010550699A JP 2010550699 A JP2010550699 A JP 2010550699A JP 2011512871 A5 JP2011512871 A5 JP 2011512871A5
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JP
Japan
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item
mrna
cells
locus
expressed
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JP2010550699A
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Japanese (ja)
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JP2011512871A (ja
JP5670755B2 (ja
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Priority claimed from PCT/US2009/001614 external-priority patent/WO2009114185A2/en
Publication of JP2011512871A publication Critical patent/JP2011512871A/ja
Publication of JP2011512871A5 publication Critical patent/JP2011512871A5/ja
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Publication of JP5670755B2 publication Critical patent/JP5670755B2/ja
Expired - Fee Related legal-status Critical Current
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JP2010550699A 2008-03-12 2009-03-12 翻訳プロファイリング及び分子表現型解析のための方法及び組成物 Expired - Fee Related JP5670755B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US3604908P 2008-03-12 2008-03-12
US3605808P 2008-03-12 2008-03-12
US61/036,058 2008-03-12
US61/036,049 2008-03-12
US7032708P 2008-03-21 2008-03-21
US61/070,327 2008-03-21
US19910808P 2008-11-12 2008-11-12
US61/199,108 2008-11-12
PCT/US2009/001614 WO2009114185A2 (en) 2008-03-12 2009-03-12 Methods and compositions for translational profiling and molecular phenotyping

Publications (3)

Publication Number Publication Date
JP2011512871A JP2011512871A (ja) 2011-04-28
JP2011512871A5 true JP2011512871A5 (https=) 2013-04-04
JP5670755B2 JP5670755B2 (ja) 2015-02-18

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JP2010550699A Expired - Fee Related JP5670755B2 (ja) 2008-03-12 2009-03-12 翻訳プロファイリング及び分子表現型解析のための方法及び組成物

Country Status (4)

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US (3) US20110071049A1 (https=)
EP (2) EP3369827B1 (https=)
JP (1) JP5670755B2 (https=)
WO (1) WO2009114185A2 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002350039A1 (en) 2001-10-29 2003-05-12 Renovis, Inc. Method for isolating cell-type specific mrnas
EP3369827B1 (en) 2008-03-12 2020-12-23 The Rockefeller University Methods and compositions for translational profiling and molecular phenotyping
EP2271358B1 (en) * 2008-03-25 2018-11-21 Amarantus Therapeutics, Inc. use of mesencephalic astrocyte-derived neurotrophic factor for treating Parkinson's disease
US10267796B2 (en) * 2010-10-25 2019-04-23 The Procter & Gamble Company Screening methods of modulating adrenergic receptor gene expressions implicated in melanogenesis
AU2012223136B2 (en) * 2011-03-02 2017-05-25 Berg Llc Interrogatory cell-based assays and uses thereof
WO2012145459A2 (en) 2011-04-22 2012-10-26 International Park Of Creativity Glucose and insulin sensors and methods of use thereof
WO2013003801A2 (en) 2011-06-29 2013-01-03 The Trustees Of Columbia University In The City Of New York Inhibitor of neuronal connectivity linked to schizophrenia susceptibility and cognitive dysfunction
US20150141274A1 (en) * 2012-05-09 2015-05-21 The Rockefeller University Methods and Compositions for Activity Dependent Transcriptome Profiling
WO2014075093A1 (en) * 2012-11-09 2014-05-15 The Trustees Of Columbia University In The City Of New York Inhibitors of central nervous system vasoactive inhibitory peptide receptor 2
DK2954323T3 (da) * 2013-02-07 2020-07-20 Univ California Anvendelse af translationsprofilering til identifikation af målmolekyler til terapeutisk behandling
EP2908137A1 (en) 2014-02-14 2015-08-19 Institut Pasteur Methods for in vitro investigating mitochondrial replication dysfunction in a biological sample, kits and uses thereof, therapeutic methods against progeroid-like syndromes or symptomes and screening method for identifying particular protease inhibitor(s) and/or nitroso-redox stress scavenger compound(s)
JP7019590B2 (ja) 2016-03-31 2022-02-15 バークレー ライツ，インコーポレイテッド 核酸安定化試薬、キット、及びその使用方法
SE540173C2 (en) * 2016-04-20 2018-04-24 Hiloprobe Ab Marker genes for colorectal cancer classification, method for judging lymph node metastasis for prognosis of colorectal cancer and kit therefor
IL268417B2 (en) * 2017-02-10 2025-05-01 Univ Rockefeller Methods for cell-type specific profiling to identify drug targets
US12590288B2 (en) 2017-04-12 2026-03-31 The Broad Institute, Inc. Method of treating an inflammatory disease by administering an agent which binds a surface receptor on a tuft cell that induces an ILC class 2 inflammatory response
US11227692B2 (en) * 2017-12-28 2022-01-18 International Business Machines Corporation Neuron model simulation
CN109813912B (zh) * 2019-01-04 2021-12-28 深圳大学 一组血清差异蛋白组合在制备用于检测孤独症的试剂中的应用
CN113621621A (zh) * 2021-08-31 2021-11-09 河南牧业经济学院 一种靶向奶山羊CIDEa基因的小干扰RNA及其应用
CN114350705A (zh) * 2021-11-16 2022-04-15 南方医科大学 一种转基因斑马鱼在制备特异标记原始红系造血过程的动物模型中的应用
CN114525241B (zh) * 2021-12-31 2023-06-20 中国人民解放军军事科学院军事医学研究院 SAFit2、培养基在促进人源诱导型多能干细胞向多巴胺能神经元分化中的应用
CN118947634B (zh) * 2024-09-30 2025-09-26 深圳市勤业医药科技有限公司 一种利用Cre-loxP系统来制备Scn1a+/-模型小鼠的新方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873191A (en) 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4870009A (en) 1982-11-22 1989-09-26 The Salk Institute For Biological Studies Method of obtaining gene product through the generation of transgenic animals
US4703004A (en) 1984-01-24 1987-10-27 Immunex Corporation Synthesis of protein with an identification peptide
US4736866B1 (en) 1984-06-22 1988-04-12 Transgenic non-human mammals
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US5075227A (en) * 1989-03-07 1991-12-24 Zymogenetics, Inc. Directional cloning
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
EP0945515A3 (en) 1989-11-06 2002-08-21 Cell Genesys, Inc. Production of proteins using homologous recombination
US5272071A (en) 1989-12-22 1993-12-21 Applied Research Systems Ars Holding N.V. Method for the modification of the expression characteristics of an endogenous gene of a given cell line
DE4237113B4 (de) 1992-11-03 2006-10-12 "Iba Gmbh" Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins
US5795723A (en) * 1994-05-06 1998-08-18 Fred Hutchinson Cancer Research Center Expression of neurogenic bHLH genes in primitive neuroectodermal tumors
EP2322614A1 (en) * 1995-06-07 2011-05-18 Life Technologies Corporation Recombinational cloning using engineered recombination sites
GB9517780D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517779D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
EP0952767A4 (en) * 1995-11-13 2001-10-24 Univ Rochester PRODUCTION OF ONE SOMATIC MOSAIC IN MAMMALS USING A RECOMBINATIVE SUBSTRATE
US6495318B2 (en) * 1996-06-17 2002-12-17 Vectorobjects, Llc Method and kits for preparing multicomponent nucleic acid constructs
US6124128A (en) * 1996-08-16 2000-09-26 The Regents Of The University Of California Long wavelength engineered fluorescent proteins
US6162965A (en) 1997-06-02 2000-12-19 Novartis Ag Plant transformation methods
EP0998574A1 (en) 1997-06-23 2000-05-10 The Rockefeller University Methods of performing homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acids
US6130090A (en) * 1997-06-23 2000-10-10 The Rockefeller University Methods of performing gene trapping in bacterial and bacteriophage-derived artificial chromosomes and use thereof
US6821759B1 (en) * 1997-06-23 2004-11-23 The Rockefeller University Methods of performing homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof
US6143566A (en) * 1997-06-23 2000-11-07 The Rockfeller University Methods of performing homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof
US6156574A (en) * 1997-06-23 2000-12-05 The Rockefeller University Methods of performing gene trapping in bacterial and bacteriophage-derived artificial chromosomes and use thereof
JP3736617B2 (ja) * 1997-12-12 2006-01-18 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 細胞型の決定方法
US6265163B1 (en) 1998-01-09 2001-07-24 Lynx Therapeutics, Inc. Solid phase selection of differentially expressed genes
US7297482B2 (en) * 1998-10-08 2007-11-20 Rigel Pharmaceuticals, Inc. Structurally biased random peptide libraries based on different scaffolds
JP4475814B2 (ja) 1998-11-20 2010-06-09 扶桑薬品工業株式会社 タンパク質発現ベクターとその使用
AU781628B2 (en) * 1999-07-14 2005-06-02 Clontech Laboratories, Inc. Recombinase-based methods for producing expression vectors and compositions for use in practicing the same
AU6229800A (en) 1999-07-20 2001-02-05 Rockefeller University, The Conditional homologous recombination of large genomic vector inserts
NZ539430A (en) * 1999-12-10 2006-09-29 Invitrogen Corp Use of multiple recombination sites with unique specificity in recombinational cloning
US6635422B2 (en) * 1999-12-28 2003-10-21 Ribonomics, Inc. Methods for isolating and characterizing endogenous mRNA-protein (mRNP) complexes
MXPA02007787A (es) 2000-02-11 2004-09-10 Inst Genetics Llc Moleculas trade y uso relacionado con las mismas.
US20030051266A1 (en) 2001-02-14 2003-03-13 Serafini Tito Andrew Collections of transgenic animal lines (living library)
HUP0402659A3 (en) * 2001-05-30 2008-07-28 Glaxo Group Ltd Chromosome-based platforms
DE60236182D1 (de) * 2001-09-14 2010-06-10 Cellectis Zufällige integration von polynukleotide nach in vivo linearisierung
AU2002350039A1 (en) * 2001-10-29 2003-05-12 Renovis, Inc. Method for isolating cell-type specific mrnas
WO2003064604A2 (en) * 2002-01-25 2003-08-07 The Board Of Trustees Of The Leland Stanford Junior University Translation profiling
US20060183147A1 (en) * 2005-02-11 2006-08-17 Elan Pharmaceuticals, Inc. Methods of identifying genes which modulate myelination
EP3369827B1 (en) 2008-03-12 2020-12-23 The Rockefeller University Methods and compositions for translational profiling and molecular phenotyping

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