JP2011510009A5 - - Google Patents
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- Publication number
- JP2011510009A5 JP2011510009A5 JP2010543200A JP2010543200A JP2011510009A5 JP 2011510009 A5 JP2011510009 A5 JP 2011510009A5 JP 2010543200 A JP2010543200 A JP 2010543200A JP 2010543200 A JP2010543200 A JP 2010543200A JP 2011510009 A5 JP2011510009 A5 JP 2011510009A5
- Authority
- JP
- Japan
- Prior art keywords
- prodrug
- formula
- pharmaceutically acceptable
- acceptable salt
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 10
- 229940002612 prodrug Drugs 0.000 claims 7
- 239000000651 prodrug Substances 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- 229910052760 oxygen Inorganic materials 0.000 claims 4
- 229910052717 sulfur Inorganic materials 0.000 claims 4
- 125000004432 carbon atom Chemical group C* 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 201000004384 Alopecia Diseases 0.000 claims 1
- 208000010412 Glaucoma Diseases 0.000 claims 1
- 208000025309 Hair disease Diseases 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 230000003676 hair loss Effects 0.000 claims 1
- 125000001072 heteroaryl group Chemical group 0.000 claims 1
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 1
- 208000003906 hydrocephalus Diseases 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 125000002950 monocyclic group Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2217208P | 2008-01-18 | 2008-01-18 | |
| US12/352,903 US8063033B2 (en) | 2008-01-18 | 2009-01-13 | Therapeutic beta-lactams |
| PCT/US2009/030894 WO2009091764A2 (en) | 2008-01-18 | 2009-01-14 | Therapeutic beta-lactams |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011510009A JP2011510009A (ja) | 2011-03-31 |
| JP2011510009A5 true JP2011510009A5 (enExample) | 2012-03-01 |
Family
ID=40876971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010543200A Pending JP2011510009A (ja) | 2008-01-18 | 2009-01-14 | 緑内障、高眼圧、禿頭症及び脱毛症の治療用ベータラクタム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8063033B2 (enExample) |
| EP (1) | EP2321304A2 (enExample) |
| JP (1) | JP2011510009A (enExample) |
| AU (1) | AU2009205477A1 (enExample) |
| BR (1) | BRPI0906846A2 (enExample) |
| CA (1) | CA2712264A1 (enExample) |
| WO (1) | WO2009091764A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7772392B2 (en) * | 2005-05-06 | 2010-08-10 | Allergan, Inc. | Therapeutic substituted β-lactams |
| CA2602535A1 (en) * | 2005-05-06 | 2006-11-16 | Allergan, Inc. | Substituted beta-lactams and their use in medicine |
| JP5524047B2 (ja) * | 2007-05-23 | 2014-06-18 | アラーガン インコーポレイテッド | 緑内障および眼圧上昇の治療用環状ラクタム類 |
| US8440819B2 (en) * | 2008-02-22 | 2013-05-14 | Allergan, Inc. | Therapeutic substituted beta-lactams |
| US8202855B2 (en) * | 2008-03-04 | 2012-06-19 | Allergan, Inc | Substituted beta-lactams |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) * | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) * | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) * | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| GB8329559D0 (en) * | 1983-11-04 | 1983-12-07 | Erba Farmitalia | Furyl derivatives of 16-substituted prostaglandins preparations |
| PT674516E (pt) | 1992-12-16 | 2000-05-31 | Agouron Pharma | Compostos de 5-tiapirimidinona e 5-selenopirimidinona substituidos antiproliferativos |
| US5462968A (en) * | 1994-01-19 | 1995-10-31 | Allergan, Inc. | EP2 -receptor agonists as agents for lowering intraocular pressure |
| US5698598A (en) * | 1995-08-04 | 1997-12-16 | Allergan | EP2 -receptor agonists as agents for lowering intraocular pressure |
| US6090847A (en) * | 1997-11-21 | 2000-07-18 | Allergan Sales, Inc. | EP2 -receptor agonists as neuroprotective agents for the eye |
| US6437146B1 (en) * | 1998-09-25 | 2002-08-20 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compounds as prostaglandin e2 agonists or antagonists |
| EA200300379A1 (ru) * | 2000-11-27 | 2003-08-28 | Пфайзер Продактс Инк. | Селективные агонисты рецептора ep4 в лечении остеопороза |
| RU2288913C2 (ru) * | 2001-07-16 | 2006-12-10 | Ф.Хоффманн-Ля Рош Аг | Аналоги простагландинов, способ их получения и фармацевтическая композиция, обладающая селективной агонистической активностью в отношении рецептора ep4 |
| BR0213911A (pt) * | 2001-11-05 | 2004-09-28 | Allergan Inc | Análogos de Èmega-cicloalquil 17-heteroaril prostaglandina e2 como agonistas do receptor ep2 |
| AU2003207900A1 (en) * | 2002-03-18 | 2003-09-29 | Pfizer Products Inc. | Methods of treatment with selective ep4 receptor agonists |
| US7091231B2 (en) * | 2004-12-10 | 2006-08-15 | Allergan, Inc. | 12-Aryl prostaglandin analogs |
| US7772392B2 (en) * | 2005-05-06 | 2010-08-10 | Allergan, Inc. | Therapeutic substituted β-lactams |
| CA2602535A1 (en) * | 2005-05-06 | 2006-11-16 | Allergan, Inc. | Substituted beta-lactams and their use in medicine |
| WO2006121822A1 (en) | 2005-05-06 | 2006-11-16 | Allergan, Inc. | USE OF β-LACTAMS FOR THE TREATMENTOF IBD AND GLAUCOMA |
| US7674786B2 (en) * | 2005-05-06 | 2010-03-09 | Allergan, Inc. | Therapeutic β-lactams |
| US7427685B2 (en) * | 2005-12-06 | 2008-09-23 | Allergan, Inc. | Therapeutic substituted cyclopentanes |
| US20070254920A1 (en) * | 2006-04-26 | 2007-11-01 | Aerie Pharmaceuticals, Inc. | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use |
| US8202855B2 (en) * | 2008-03-04 | 2012-06-19 | Allergan, Inc | Substituted beta-lactams |
-
2009
- 2009-01-13 US US12/352,903 patent/US8063033B2/en active Active
- 2009-01-14 JP JP2010543200A patent/JP2011510009A/ja active Pending
- 2009-01-14 EP EP09702401A patent/EP2321304A2/en not_active Withdrawn
- 2009-01-14 AU AU2009205477A patent/AU2009205477A1/en not_active Abandoned
- 2009-01-14 CA CA2712264A patent/CA2712264A1/en not_active Abandoned
- 2009-01-14 WO PCT/US2009/030894 patent/WO2009091764A2/en not_active Ceased
- 2009-01-14 BR BRPI0906846-5A patent/BRPI0906846A2/pt not_active IP Right Cessation
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