JP2011519910A5 - - Google Patents
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- Publication number
- JP2011519910A5 JP2011519910A5 JP2011508009A JP2011508009A JP2011519910A5 JP 2011519910 A5 JP2011519910 A5 JP 2011519910A5 JP 2011508009 A JP2011508009 A JP 2011508009A JP 2011508009 A JP2011508009 A JP 2011508009A JP 2011519910 A5 JP2011519910 A5 JP 2011519910A5
- Authority
- JP
- Japan
- Prior art keywords
- ono
- independently
- alkyl
- cycloalkoxy
- alkoxyalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5208408P | 2008-05-09 | 2008-05-09 | |
| US61/052,084 | 2008-05-09 | ||
| US13933308P | 2008-12-19 | 2008-12-19 | |
| US61/139,333 | 2008-12-19 | ||
| PCT/IB2009/005594 WO2009136281A1 (en) | 2008-05-09 | 2009-05-11 | Nitric oxide donating prostamides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011519910A JP2011519910A (ja) | 2011-07-14 |
| JP2011519910A5 true JP2011519910A5 (enExample) | 2012-03-15 |
| JP5401540B2 JP5401540B2 (ja) | 2014-01-29 |
Family
ID=41020929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011508009A Active JP5401540B2 (ja) | 2008-05-09 | 2009-05-11 | 硝酸酸化物供与プロスタミド類 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8101658B2 (enExample) |
| EP (1) | EP2274279B1 (enExample) |
| JP (1) | JP5401540B2 (enExample) |
| CN (1) | CN102099330B (enExample) |
| AR (1) | AR076731A1 (enExample) |
| CA (1) | CA2723704C (enExample) |
| ES (1) | ES2428387T3 (enExample) |
| WO (1) | WO2009136281A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8519178B2 (en) | 2009-06-22 | 2013-08-27 | Johnson Matthey Public Limited Company | Method for the purification of prostaglandins |
| JP5885271B2 (ja) * | 2011-02-14 | 2016-03-15 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ビマトプロストのエステル誘導体の組成物および方法 |
| WO2013132497A1 (en) | 2012-03-07 | 2013-09-12 | Advanced Inhilation Therapies (Ait) Ltd. | Inhalation of nitric oxide for treating respiratory diseases |
| CA2871292A1 (en) | 2012-05-31 | 2013-12-05 | Theravance Biopharma R&D Ip, Llc | Nitric oxide donor neprilysin inhibitors |
| US10047047B2 (en) | 2015-03-31 | 2018-08-14 | Nicox S.A. | Nitric oxide donating derivatives of latanoprost free acid |
| WO2016155906A1 (en) | 2015-03-31 | 2016-10-06 | Nicox S.A. | Nitric oxide donating derivatives of fluprostenol |
| EP3088388A1 (en) | 2015-04-30 | 2016-11-02 | NicOx S.A. | Nitric oxide donating derivatives of prostaglandins |
| EP4548975A3 (en) | 2015-09-09 | 2025-07-23 | Beyond Air Ltd | Nitric oxide inhalation therapy for infants with bronchiolitis |
| JP7055802B2 (ja) | 2016-11-08 | 2022-04-18 | ボシュ・アンド・ロム・インコーポレイテッド | 正常眼圧緑内障を処置するための一酸化窒素放出プロスタグランジン誘導体 |
| EP3757089B1 (en) * | 2018-02-21 | 2022-05-11 | Nicox S.A. | Process for the preparation of a nitric oxide donating prostaglandin analogue |
| RU2718744C2 (ru) | 2018-05-17 | 2020-04-14 | Общество с ограниченной ответственностью "Гурус БиоФарм" | Производные простагландина F2альфа для снижения внутриглазного давления |
| CA3105989A1 (en) * | 2018-07-12 | 2020-01-16 | Nicox S.A. | Ophthalmic compositions containing a nitric oxide releasing prostamide |
| HUE064405T2 (hu) * | 2019-08-05 | 2024-03-28 | Nicox Sa | Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására |
| ES3017242T3 (en) * | 2021-02-03 | 2025-05-12 | Nicox Sa | Process for the preparation of a nitric oxide donating prostaglandin analogue |
| CN117979973A (zh) | 2021-09-20 | 2024-05-03 | 尼科斯股份有限公司 | 作为神经保护剂的释放一氧化氮的前列腺酰胺 |
| CN113943266A (zh) * | 2021-11-18 | 2022-01-18 | 广州楷石医药有限公司 | 一种氧化氮供体型贝前列素类衍生物及其药物组合物和用途 |
| MA71652A (fr) | 2022-07-07 | 2025-05-30 | Nicox S.A. | Procédé industriel pour la préparation d'acide hexanoique, 6-(nitrooxy)-, (1s,2e)-3-(1r,2r,3s,5r)-2- (2z)-7-(éthylamino)-7-oxo-2-hepten-1-yl) |
| CN115677549A (zh) * | 2022-10-27 | 2023-02-03 | 神隆医药（常熟）有限公司 | 一种贝美前列素手性异构体的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352708A (en) * | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US6395787B1 (en) * | 2000-02-08 | 2002-05-28 | Allergan Sales, Inc. | Ocular hypotensive lipids |
| TWI298257B (en) * | 2001-05-31 | 2008-07-01 | Allergan Inc | Hypotensive lipid and timolol compositions and methods of using same |
| EP1336602A1 (en) * | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
| JP2005519115A (ja) * | 2002-03-01 | 2005-06-30 | アラーガン、インコーポレイテッド | プロスタミドの製造 |
| EP1704141B1 (en) * | 2004-01-05 | 2016-02-24 | Nicox S.A. | Prostaglandin nitrooxyderivatives |
| WO2007000641A2 (en) * | 2005-06-29 | 2007-01-04 | Pfizer Inc. | Prostaglandin derivatives |
| US20070015838A1 (en) * | 2005-07-14 | 2007-01-18 | Allergan, Inc. | Cyclopentane n-lower alkyl heptenamide-5-cis-2-(3alpha-hydroxy-5-phenylpentyl)-3, 5-dihydroxy, [1alpha, 2beta, 3alpha, 5alpha] compounds as agents for lowering intraocular pressure |
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2009
- 2009-05-07 AR ARP090101651A patent/AR076731A1/es active IP Right Grant
- 2009-05-11 JP JP2011508009A patent/JP5401540B2/ja active Active
- 2009-05-11 US US12/991,855 patent/US8101658B2/en active Active
- 2009-05-11 CA CA2723704A patent/CA2723704C/en active Active
- 2009-05-11 ES ES09742454T patent/ES2428387T3/es active Active
- 2009-05-11 WO PCT/IB2009/005594 patent/WO2009136281A1/en not_active Ceased
- 2009-05-11 EP EP09742454.3A patent/EP2274279B1/en active Active
- 2009-05-11 CN CN200980127115.4A patent/CN102099330B/zh active Active