JP2011519910A5 - - Google Patents
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- Publication number
- JP2011519910A5 JP2011519910A5 JP2011508009A JP2011508009A JP2011519910A5 JP 2011519910 A5 JP2011519910 A5 JP 2011519910A5 JP 2011508009 A JP2011508009 A JP 2011508009A JP 2011508009 A JP2011508009 A JP 2011508009A JP 2011519910 A5 JP2011519910 A5 JP 2011519910A5
- Authority
- JP
- Japan
- Prior art keywords
- ono
- independently
- alkyl
- cycloalkoxy
- alkoxyalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5208408P | 2008-05-09 | 2008-05-09 | |
| US61/052,084 | 2008-05-09 | ||
| US13933308P | 2008-12-19 | 2008-12-19 | |
| US61/139,333 | 2008-12-19 | ||
| PCT/IB2009/005594 WO2009136281A1 (en) | 2008-05-09 | 2009-05-11 | Nitric oxide donating prostamides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011519910A JP2011519910A (ja) | 2011-07-14 |
| JP2011519910A5 true JP2011519910A5 (enExample) | 2012-03-15 |
| JP5401540B2 JP5401540B2 (ja) | 2014-01-29 |
Family
ID=41020929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011508009A Active JP5401540B2 (ja) | 2008-05-09 | 2009-05-11 | 硝酸酸化物供与プロスタミド類 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8101658B2 (enExample) |
| EP (1) | EP2274279B1 (enExample) |
| JP (1) | JP5401540B2 (enExample) |
| CN (1) | CN102099330B (enExample) |
| AR (1) | AR076731A1 (enExample) |
| CA (1) | CA2723704C (enExample) |
| ES (1) | ES2428387T3 (enExample) |
| WO (1) | WO2009136281A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6087147B2 (ja) * | 2009-06-22 | 2017-03-01 | ジョンソン、マッセイ、パブリック、リミテッド、カンパニーＪｏｈｎｓｏｎ Ｍａｔｔｈｅｙ Ｐｕｂｌｉｃ Ｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ | プロスタグランジンの精製方法 |
| WO2012112451A1 (en) * | 2011-02-14 | 2012-08-23 | Allergan, Inc. | Ester derivatives of bimatoprost compositions and methods |
| US20150272988A1 (en) | 2012-03-07 | 2015-10-01 | Advanced Inhalation Therapies (Ait) Ltd. | Inhalation of nitric oxide for treating respiratory diseases |
| CA2871292A1 (en) | 2012-05-31 | 2013-12-05 | Theravance Biopharma R&D Ip, Llc | Nitric oxide donor neprilysin inhibitors |
| US10280138B2 (en) | 2015-03-31 | 2019-05-07 | Nicox S.A. | Nitric oxide donating derivatives of fluprostenol |
| US10047047B2 (en) | 2015-03-31 | 2018-08-14 | Nicox S.A. | Nitric oxide donating derivatives of latanoprost free acid |
| EP3088388A1 (en) | 2015-04-30 | 2016-11-02 | NicOx S.A. | Nitric oxide donating derivatives of prostaglandins |
| EP3347096A4 (en) | 2015-09-09 | 2019-05-15 | Advanced Inhalation Therapies (AIT) Ltd. | STICK OXIDE INHALATION THERAPY FOR SMALL CHILDREN WITH BRONCHIOLITIS |
| BR112019009330A2 (pt) | 2016-11-08 | 2019-07-30 | Bausch & Lomb | composto |
| ES2836118T3 (es) * | 2018-02-21 | 2021-06-24 | Nicox Sa | Procedimiento para la preparación de un análogo de prostaglandina donante de óxido nítrico |
| RU2718744C2 (ru) | 2018-05-17 | 2020-04-14 | Общество с ограниченной ответственностью "Гурус БиоФарм" | Производные простагландина F2альфа для снижения внутриглазного давления |
| US10688073B2 (en) * | 2018-07-12 | 2020-06-23 | Nicox Sa | Ophthalmic compositions containing a nitric oxide releasing prostamide |
| EP3772511B1 (en) * | 2019-08-05 | 2023-11-08 | Nicox S.A. | Process for the preparation of a nitric oxide donating prostaglandin analogue |
| ES3017242T3 (en) * | 2021-02-03 | 2025-05-12 | Nicox Sa | Process for the preparation of a nitric oxide donating prostaglandin analogue |
| US20240390390A1 (en) | 2021-09-20 | 2024-11-28 | Nicox Sa | Nitric oxide releasing prostamide as neuroprotective agent |
| CN119350280A (zh) * | 2021-11-18 | 2025-01-24 | 广州楷石医药有限公司 | 一种氧化氮供体型贝前列素类衍生物及其药物组合物和用途 |
| EP4410294A3 (en) | 2022-07-07 | 2024-11-06 | Nicox S.A. | Industrial process for the preparation of hexanoic acid, 6(nitrooxy)-,(1s,2e)-3-[(1r,2r,3s,5r)-2-[(2z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]3,5-dihydroxycyclopentyl]-1-(2-phenyl ethyl)-2-propen-1-yl ester and high pure product |
| CN115677549A (zh) * | 2022-10-27 | 2023-02-03 | 神隆医药（常熟）有限公司 | 一种贝美前列素手性异构体的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352708A (en) * | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US6395787B1 (en) * | 2000-02-08 | 2002-05-28 | Allergan Sales, Inc. | Ocular hypotensive lipids |
| TWI298257B (en) * | 2001-05-31 | 2008-07-01 | Allergan Inc | Hypotensive lipid and timolol compositions and methods of using same |
| EP1336602A1 (en) * | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
| EP1480949B1 (en) * | 2002-03-01 | 2015-04-29 | Allergan, Inc. | Preparation of prostamides |
| JP3984283B2 (ja) * | 2004-01-05 | 2007-10-03 | ニコックス，ソシエテ アノニム | プロスタグランヂンニトロオキシ誘導体 |
| WO2007000641A2 (en) * | 2005-06-29 | 2007-01-04 | Pfizer Inc. | Prostaglandin derivatives |
| US20070015838A1 (en) * | 2005-07-14 | 2007-01-18 | Allergan, Inc. | Cyclopentane n-lower alkyl heptenamide-5-cis-2-(3alpha-hydroxy-5-phenylpentyl)-3, 5-dihydroxy, [1alpha, 2beta, 3alpha, 5alpha] compounds as agents for lowering intraocular pressure |
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2009
- 2009-05-07 AR ARP090101651A patent/AR076731A1/es active IP Right Grant
- 2009-05-11 ES ES09742454T patent/ES2428387T3/es active Active
- 2009-05-11 WO PCT/IB2009/005594 patent/WO2009136281A1/en not_active Ceased
- 2009-05-11 CA CA2723704A patent/CA2723704C/en active Active
- 2009-05-11 CN CN200980127115.4A patent/CN102099330B/zh active Active
- 2009-05-11 JP JP2011508009A patent/JP5401540B2/ja active Active
- 2009-05-11 EP EP09742454.3A patent/EP2274279B1/en active Active
- 2009-05-11 US US12/991,855 patent/US8101658B2/en active Active