JP2011506463A5 - - Google Patents
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- Publication number
- JP2011506463A5 JP2011506463A5 JP2010538112A JP2010538112A JP2011506463A5 JP 2011506463 A5 JP2011506463 A5 JP 2011506463A5 JP 2010538112 A JP2010538112 A JP 2010538112A JP 2010538112 A JP2010538112 A JP 2010538112A JP 2011506463 A5 JP2011506463 A5 JP 2011506463A5
- Authority
- JP
- Japan
- Prior art keywords
- naphthalen
- ylamino
- tetrahydro
- diethyl
- methoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US722007P | 2007-12-11 | 2007-12-11 | |
| US61/007,220 | 2007-12-11 | ||
| US4921908P | 2008-04-30 | 2008-04-30 | |
| US61/049,219 | 2008-04-30 | ||
| PCT/US2008/086171 WO2009076408A2 (en) | 2007-12-11 | 2008-12-10 | 3 -carboxypropyl-aminotetralin derivatives as mu opioid receptor antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011506463A JP2011506463A (ja) | 2011-03-03 |
| JP2011506463A5 true JP2011506463A5 (https=) | 2012-11-08 |
| JP5403762B2 JP5403762B2 (ja) | 2014-01-29 |
Family
ID=40521484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538112A Expired - Fee Related JP5403762B2 (ja) | 2007-12-11 | 2008-12-10 | μオピオイド受容体アンタゴニストとしての３−カルボキシプロピル−アミノテトラリン誘導体 |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US8106232B2 (https=) |
| EP (1) | EP2231585B1 (https=) |
| JP (1) | JP5403762B2 (https=) |
| KR (1) | KR101610165B1 (https=) |
| CN (1) | CN101896455B (https=) |
| AR (1) | AR072336A1 (https=) |
| AU (1) | AU2008335210B2 (https=) |
| BR (1) | BRPI0821611A8 (https=) |
| CA (1) | CA2707981C (https=) |
| CL (1) | CL2008003672A1 (https=) |
| CO (1) | CO6300937A2 (https=) |
| ES (1) | ES2402749T3 (https=) |
| IL (1) | IL205949A (https=) |
| MY (1) | MY149973A (https=) |
| NZ (1) | NZ586048A (https=) |
| RU (1) | RU2482107C2 (https=) |
| TW (1) | TWI412360B (https=) |
| WO (1) | WO2009076408A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
| KR101456722B1 (ko) * | 2006-03-29 | 2014-10-31 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 디아릴티오히단토인 화합물 |
| TWI469971B (zh) | 2007-10-26 | 2015-01-21 | Univ California | 二芳基乙內醯脲類化合物 |
| WO2009076399A2 (en) | 2007-12-11 | 2009-06-18 | Theravance, Inc. | Aminotetralin compounds as mu opioid receptor antagonists |
| US8153686B2 (en) * | 2008-04-01 | 2012-04-10 | Theravance, Inc. | Amino- and amido-aminotetralin derivatives and related compounds as mu opioid receptor antagonists |
| JP5650657B2 (ja) | 2008-12-10 | 2015-01-07 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | ３−カルボキシプロピル−アミノテトラリン化合物の結晶形態 |
| AU2010295464B2 (en) * | 2009-09-18 | 2015-11-26 | Merck Sharp & Dohme Corp. | Use of opioid receptor antagonist for gastrointestinal tract disorders |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69032725T2 (de) * | 1989-05-31 | 1999-04-08 | Pharmacia & Upjohn Co., Kalamazoo, Mich. | ZNS-wirksame 8-Heterocyclyl-2-aminotetralin Derivate |
| US6844368B1 (en) | 1998-12-22 | 2005-01-18 | Edward Roberts | Compounds useful in pain management |
| JP2002533320A (ja) * | 1998-12-22 | 2002-10-08 | アストラゼネカ・アクチエボラーグ | 疼痛管理に有用な新規なオキソ−アミノテトラリン化合物 |
| EP1140815A1 (en) * | 1998-12-22 | 2001-10-10 | AstraZeneca AB | Novel thio-aminotetralin compounds useful in pain management |
| US6498196B1 (en) | 1998-12-22 | 2002-12-24 | Edward Roberts | Compounds useful in pain management |
| US6231594B1 (en) * | 1999-08-11 | 2001-05-15 | Radiant Medical, Inc. | Method of controlling body temperature while reducing shivering |
| JP2010509227A (ja) | 2006-11-07 | 2010-03-25 | ネクター セラピューティックス エイエル，コーポレイション | オピオイド作動薬およびオピオイド拮抗薬の用量形態および同時投与 |
| WO2009076399A2 (en) | 2007-12-11 | 2009-06-18 | Theravance, Inc. | Aminotetralin compounds as mu opioid receptor antagonists |
| US8153686B2 (en) | 2008-04-01 | 2012-04-10 | Theravance, Inc. | Amino- and amido-aminotetralin derivatives and related compounds as mu opioid receptor antagonists |
| JP5650657B2 (ja) | 2008-12-10 | 2015-01-07 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | ３−カルボキシプロピル−アミノテトラリン化合物の結晶形態 |
-
2008
- 2008-12-10 RU RU2010128542/04A patent/RU2482107C2/ru active
- 2008-12-10 ES ES08859864T patent/ES2402749T3/es active Active
- 2008-12-10 BR BRPI0821611A patent/BRPI0821611A8/pt not_active Application Discontinuation
- 2008-12-10 KR KR1020107014774A patent/KR101610165B1/ko not_active Expired - Fee Related
- 2008-12-10 CL CL2008003672A patent/CL2008003672A1/es unknown
- 2008-12-10 CA CA2707981A patent/CA2707981C/en active Active
- 2008-12-10 WO PCT/US2008/086171 patent/WO2009076408A2/en not_active Ceased
- 2008-12-10 MY MYPI2010002437A patent/MY149973A/en unknown
- 2008-12-10 US US12/331,659 patent/US8106232B2/en not_active Expired - Fee Related
- 2008-12-10 CN CN200880119873.7A patent/CN101896455B/zh not_active Expired - Fee Related
- 2008-12-10 EP EP08859864A patent/EP2231585B1/en not_active Not-in-force
- 2008-12-10 AR ARP080105365A patent/AR072336A1/es unknown
- 2008-12-10 AU AU2008335210A patent/AU2008335210B2/en not_active Ceased
- 2008-12-10 NZ NZ586048A patent/NZ586048A/en not_active IP Right Cessation
- 2008-12-10 TW TW097148045A patent/TWI412360B/zh not_active IP Right Cessation
- 2008-12-10 JP JP2010538112A patent/JP5403762B2/ja not_active Expired - Fee Related
-
2010
- 2010-05-25 IL IL205949A patent/IL205949A/en active IP Right Grant
- 2010-06-11 CO CO10070802A patent/CO6300937A2/es not_active Application Discontinuation
-
2011
- 2011-12-19 US US13/330,363 patent/US8318765B2/en not_active Expired - Fee Related
-
2012
- 2012-10-16 US US13/652,808 patent/US8492399B2/en not_active Expired - Fee Related
-
2013
- 2013-06-19 US US13/921,448 patent/US8703791B2/en active Active
-
2014
- 2014-03-04 US US14/196,186 patent/US8969370B2/en not_active Expired - Fee Related
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