JP2011505988A5 - - Google Patents
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- Publication number
- JP2011505988A5 JP2011505988A5 JP2010538164A JP2010538164A JP2011505988A5 JP 2011505988 A5 JP2011505988 A5 JP 2011505988A5 JP 2010538164 A JP2010538164 A JP 2010538164A JP 2010538164 A JP2010538164 A JP 2010538164A JP 2011505988 A5 JP2011505988 A5 JP 2011505988A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- elastic wire
- elastomeric tube
- tube
- drug reservoir
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940079593 drug Drugs 0.000 claims 23
- 239000003814 drug Substances 0.000 claims 23
- 239000013583 drug formulation Substances 0.000 claims 6
- 229920001971 elastomer Polymers 0.000 claims 5
- 239000000806 elastomer Substances 0.000 claims 5
- 230000003204 osmotic effect Effects 0.000 claims 5
- 230000014759 maintenance of location Effects 0.000 claims 4
- 229920001296 polysiloxane Polymers 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- 239000003589 local anesthetic agent Substances 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 2
- NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical compound C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 claims 2
- 229920006465 Styrenic thermoplastic elastomer Polymers 0.000 claims 2
- 229910045601 alloy Inorganic materials 0.000 claims 2
- 239000000956 alloy Substances 0.000 claims 2
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 claims 2
- LKFHUFAEFBRVQX-UHFFFAOYSA-N decanedioic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.OC(=O)CCCCCCCCC(O)=O LKFHUFAEFBRVQX-UHFFFAOYSA-N 0.000 claims 2
- 238000001727 in vivo Methods 0.000 claims 2
- 230000008595 infiltration Effects 0.000 claims 2
- 238000001764 infiltration Methods 0.000 claims 2
- 229920002635 polyurethane Polymers 0.000 claims 2
- 239000004814 polyurethane Substances 0.000 claims 2
- 150000003839 salts Chemical group 0.000 claims 2
- ZKMNUMMKYBVTFN-HNNXBMFYSA-N (S)-ropivacaine Chemical compound CCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C ZKMNUMMKYBVTFN-HNNXBMFYSA-N 0.000 claims 1
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 claims 1
- XIQVNETUBQGFHX-UHFFFAOYSA-N Ditropan Chemical compound C=1C=CC=CC=1C(O)(C(=O)OCC#CCN(CC)CC)C1CCCCC1 XIQVNETUBQGFHX-UHFFFAOYSA-N 0.000 claims 1
- 229920002683 Glycosaminoglycan Polymers 0.000 claims 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims 1
- 229910001182 Mo alloy Inorganic materials 0.000 claims 1
- KCLANYCVBBTKTO-UHFFFAOYSA-N Proparacaine Chemical compound CCCOC1=CC=C(C(=O)OCCN(CC)CC)C=C1N KCLANYCVBBTKTO-UHFFFAOYSA-N 0.000 claims 1
- 229920002385 Sodium hyaluronate Polymers 0.000 claims 1
- 229960005274 benzocaine Drugs 0.000 claims 1
- 229960003150 bupivacaine Drugs 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000002131 composite material Substances 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 claims 1
- 229960001760 dimethyl sulfoxide Drugs 0.000 claims 1
- 229960000855 flavoxate Drugs 0.000 claims 1
- SPIUTQOUKAMGCX-UHFFFAOYSA-N flavoxate Chemical compound C1=CC=C2C(=O)C(C)=C(C=3C=CC=CC=3)OC2=C1C(=O)OCCN1CCCCC1 SPIUTQOUKAMGCX-UHFFFAOYSA-N 0.000 claims 1
- 229920000669 heparin Polymers 0.000 claims 1
- 229960002897 heparin Drugs 0.000 claims 1
- XPXMKIXDFWLRAA-UHFFFAOYSA-N hydrazinide Chemical compound [NH-]N XPXMKIXDFWLRAA-UHFFFAOYSA-N 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 229960004194 lidocaine Drugs 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 229960002409 mepivacaine Drugs 0.000 claims 1
- INWLQCZOYSRPNW-UHFFFAOYSA-N mepivacaine Chemical compound CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C INWLQCZOYSRPNW-UHFFFAOYSA-N 0.000 claims 1
- 229960004857 mitomycin Drugs 0.000 claims 1
- ZPZCREMGFMRIRR-UHFFFAOYSA-N molybdenum titanium Chemical compound [Ti].[Mo] ZPZCREMGFMRIRR-UHFFFAOYSA-N 0.000 claims 1
- 229910001000 nickel titanium Inorganic materials 0.000 claims 1
- 229960005434 oxybutynin Drugs 0.000 claims 1
- 229940043138 pentosan polysulfate Drugs 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 229960001807 prilocaine Drugs 0.000 claims 1
- MVFGUOIZUNYYSO-UHFFFAOYSA-N prilocaine Chemical compound CCCNC(C)C(=O)NC1=CC=CC=C1C MVFGUOIZUNYYSO-UHFFFAOYSA-N 0.000 claims 1
- 229960004919 procaine Drugs 0.000 claims 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 claims 1
- 229960003981 proparacaine Drugs 0.000 claims 1
- 229960001549 ropivacaine Drugs 0.000 claims 1
- 239000012781 shape memory material Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 229940083542 sodium Drugs 0.000 claims 1
- 229940010747 sodium hyaluronate Drugs 0.000 claims 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims 1
- 229960002372 tetracaine Drugs 0.000 claims 1
- GKCBAIGFKIBETG-UHFFFAOYSA-N tetracaine Chemical compound CCCCNC1=CC=C(C(=O)OCCN(C)C)C=C1 GKCBAIGFKIBETG-UHFFFAOYSA-N 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US717707P | 2007-12-11 | 2007-12-11 | |
| US61,007,177 | 2007-12-11 | ||
| US8492708P | 2008-07-30 | 2008-07-30 | |
| US61,084,927 | 2008-07-30 | ||
| PCT/US2008/086467 WO2009076547A2 (en) | 2007-12-11 | 2008-12-11 | Implantable drug delivery device ant) methods for treatment of the bladder and other body vestcles or lumens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011505988A JP2011505988A (ja) | 2011-03-03 |
| JP2011505988A5 true JP2011505988A5 (enExample) | 2012-08-23 |
| JP5560200B2 JP5560200B2 (ja) | 2014-07-23 |
Family
ID=40551355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538164A Active JP5560200B2 (ja) | 2007-12-11 | 2008-12-11 | 膀胱および他の身体の小嚢又は管腔を治療するための埋め込み型薬物供給デバイス |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US9586035B2 (enExample) |
| EP (1) | EP2231254B9 (enExample) |
| JP (1) | JP5560200B2 (enExample) |
| KR (1) | KR101538748B1 (enExample) |
| CN (1) | CN101896221B (enExample) |
| AU (1) | AU2008335077B2 (enExample) |
| BR (1) | BRPI0820800B8 (enExample) |
| CA (1) | CA2706384C (enExample) |
| DK (1) | DK2231254T3 (enExample) |
| EA (1) | EA201070703A1 (enExample) |
| ES (1) | ES2481454T3 (enExample) |
| IL (1) | IL205960A0 (enExample) |
| MX (1) | MX348005B (enExample) |
| NZ (1) | NZ585449A (enExample) |
| PL (1) | PL2231254T3 (enExample) |
| WO (1) | WO2009076547A2 (enExample) |
| ZA (1) | ZA201003779B (enExample) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1933810T3 (da) | 2005-08-11 | 2013-01-28 | Childrens Medical Center | Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde |
| US20100003297A1 (en) | 2005-08-11 | 2010-01-07 | Massachusetts Institute Of Technology | Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues |
| DK2231254T3 (da) | 2007-12-11 | 2014-07-21 | Massachusetts Inst Technology | Implanterbar lægemiddelafgivelsesindretning |
| US11331424B2 (en) | 2009-01-26 | 2022-05-17 | Incube Labs, Llc | Apparatus, systems and methods for delivery of medication to the brain to treat neurological conditions |
| EP2405967B1 (en) * | 2009-03-12 | 2020-09-23 | Delpor, Inc. | Implantable device for long-term delivery of drugs |
| US9014787B2 (en) | 2009-06-01 | 2015-04-21 | Focal Therapeutics, Inc. | Bioabsorbable target for diagnostic or therapeutic procedure |
| US8343516B2 (en) * | 2009-06-26 | 2013-01-01 | Taris Biomedical, Inc. | Solid drug tablets for implantable drug delivery devices |
| US20110052497A1 (en) * | 2009-08-27 | 2011-03-03 | Taris Biomedical, Inc. | Minimally Invasive Systems and Methods for In Vivo Testing of Materials |
| US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
| US8721621B2 (en) | 2009-09-10 | 2014-05-13 | Taris Biomedical, Inc. | Systems and methods for deploying devices to genitourinary sites |
| US8167836B2 (en) * | 2009-12-08 | 2012-05-01 | Taris Biomedical, Inc. | Tissue expander configured for drug delivery |
| US8679094B2 (en) * | 2009-12-17 | 2014-03-25 | Taris Biomedical, Inc. | Implantable device with intravesical tolerability and methods of treatment |
| AU2015201123B2 (en) * | 2009-12-17 | 2016-04-21 | Taris Biomedical Llc | Implantable device with intravesical tolerability and methods of treatment |
| US20110218488A1 (en) * | 2010-03-05 | 2011-09-08 | Taris Biomedical, Inc. | Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites |
| PL3517101T3 (pl) | 2010-08-05 | 2021-02-22 | Taris Biomedical Llc | Wszczepiane urządzenia do podawania leków w miejscach moczowo-płciowych |
| PT2600800T (pt) | 2010-08-05 | 2020-11-05 | Taris Biomedical Llc | Dispositivo de administração de drogas por stent ureteral, kit e método |
| US9457176B2 (en) | 2010-10-06 | 2016-10-04 | Taris Biomedical Llc | Implantable drug delivery device with bladder retention feature |
| US8690840B2 (en) | 2010-10-06 | 2014-04-08 | Taris Biomedical, Inc. | Time-selective bioresorbable or collapsible drug delivery systems and methods |
| US9114111B2 (en) * | 2011-01-10 | 2015-08-25 | Allergan, Inc. | Methods for sustained treatment of bladder pain and irritative voiding |
| WO2012106714A1 (en) | 2011-02-04 | 2012-08-09 | Taris Biomedical, Inc. | Implantable device for controlled release of low solubility drug |
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| US10058688B2 (en) | 2012-05-09 | 2018-08-28 | Massachusetts Institute Of Technology | Medicament, method, and drug delivery device for treatment of ovarian cancer |
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| KR102383496B1 (ko) | 2012-08-31 | 2022-04-08 | 타리스 바이오메디컬 엘엘씨 | 젬시타빈을 포함하는 전립선 질환의 치료를 위한 약물 전달 시스템과 방법 |
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| SE539540C2 (sv) * | 2013-09-12 | 2017-10-10 | Qpharma Ab | Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar |
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| KR102391761B1 (ko) | 2014-06-26 | 2022-04-27 | 타리스 바이오메디컬 엘엘씨 | 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법 |
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| CN106573133B (zh) * | 2014-08-19 | 2020-03-03 | 加利福尼亚大学董事会 | 用于局部药物递送的植入物及其使用方法 |
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- 2008-12-11 DK DK08859044.3T patent/DK2231254T3/da active
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