BRPI0820800B8 - dispositivo médico implantável para liberação controlada de droga - Google Patents

dispositivo médico implantável para liberação controlada de droga

Info

Publication number
BRPI0820800B8
BRPI0820800B8 BRPI0820800A BRPI0820800A BRPI0820800B8 BR PI0820800 B8 BRPI0820800 B8 BR PI0820800B8 BR PI0820800 A BRPI0820800 A BR PI0820800A BR PI0820800 A BRPI0820800 A BR PI0820800A BR PI0820800 B8 BRPI0820800 B8 BR PI0820800B8
Authority
BR
Brazil
Prior art keywords
bladder
drug
implantable medical
medical device
drug release
Prior art date
Application number
BRPI0820800A
Other languages
English (en)
Portuguese (pt)
Inventor
Lee Heejin
J Cima Michael
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of BRPI0820800A2 publication Critical patent/BRPI0820800A2/pt
Publication of BRPI0820800B1 publication Critical patent/BRPI0820800B1/pt
Publication of BRPI0820800B8 publication Critical patent/BRPI0820800B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0102—Insertion or introduction using an inner stiffening member, e.g. stylet or push-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0108—Steering means as part of the catheter or advancing means; Markers for positioning using radio-opaque or ultrasound markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1078—Urinary tract
    • A61M2210/1085—Bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Catching Or Destruction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0820800A 2007-12-11 2008-12-11 dispositivo médico implantável para liberação controlada de droga BRPI0820800B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US717707P 2007-12-11 2007-12-11
US61/007177 2007-12-11
US8492708P 2008-07-30 2008-07-30
US61/084927 2008-07-30
PCT/US2008/086467 WO2009076547A2 (en) 2007-12-11 2008-12-11 Implantable drug delivery device ant) methods for treatment of the bladder and other body vestcles or lumens

Publications (3)

Publication Number Publication Date
BRPI0820800A2 BRPI0820800A2 (pt) 2015-06-16
BRPI0820800B1 BRPI0820800B1 (pt) 2020-09-29
BRPI0820800B8 true BRPI0820800B8 (pt) 2021-06-22

Family

ID=40551355

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0820800A BRPI0820800B8 (pt) 2007-12-11 2008-12-11 dispositivo médico implantável para liberação controlada de droga

Country Status (17)

Country Link
US (4) US9586035B2 (enExample)
EP (1) EP2231254B9 (enExample)
JP (1) JP5560200B2 (enExample)
KR (1) KR101538748B1 (enExample)
CN (1) CN101896221B (enExample)
AU (1) AU2008335077B2 (enExample)
BR (1) BRPI0820800B8 (enExample)
CA (1) CA2706384C (enExample)
DK (1) DK2231254T3 (enExample)
EA (1) EA201070703A1 (enExample)
ES (1) ES2481454T3 (enExample)
IL (1) IL205960A0 (enExample)
MX (1) MX348005B (enExample)
NZ (1) NZ585449A (enExample)
PL (1) PL2231254T3 (enExample)
WO (1) WO2009076547A2 (enExample)
ZA (1) ZA201003779B (enExample)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1933810T3 (da) 2005-08-11 2013-01-28 Childrens Medical Center Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde
US20100003297A1 (en) 2005-08-11 2010-01-07 Massachusetts Institute Of Technology Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues
DK2231254T3 (da) 2007-12-11 2014-07-21 Massachusetts Inst Technology Implanterbar lægemiddelafgivelsesindretning
US11331424B2 (en) 2009-01-26 2022-05-17 Incube Labs, Llc Apparatus, systems and methods for delivery of medication to the brain to treat neurological conditions
EP2405967B1 (en) * 2009-03-12 2020-09-23 Delpor, Inc. Implantable device for long-term delivery of drugs
US9014787B2 (en) 2009-06-01 2015-04-21 Focal Therapeutics, Inc. Bioabsorbable target for diagnostic or therapeutic procedure
US8343516B2 (en) * 2009-06-26 2013-01-01 Taris Biomedical, Inc. Solid drug tablets for implantable drug delivery devices
US20110052497A1 (en) * 2009-08-27 2011-03-03 Taris Biomedical, Inc. Minimally Invasive Systems and Methods for In Vivo Testing of Materials
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
US8167836B2 (en) * 2009-12-08 2012-05-01 Taris Biomedical, Inc. Tissue expander configured for drug delivery
US8679094B2 (en) * 2009-12-17 2014-03-25 Taris Biomedical, Inc. Implantable device with intravesical tolerability and methods of treatment
AU2015201123B2 (en) * 2009-12-17 2016-04-21 Taris Biomedical Llc Implantable device with intravesical tolerability and methods of treatment
US20110218488A1 (en) * 2010-03-05 2011-09-08 Taris Biomedical, Inc. Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites
PL3517101T3 (pl) 2010-08-05 2021-02-22 Taris Biomedical Llc Wszczepiane urządzenia do podawania leków w miejscach moczowo-płciowych
PT2600800T (pt) 2010-08-05 2020-11-05 Taris Biomedical Llc Dispositivo de administração de drogas por stent ureteral, kit e método
US9457176B2 (en) 2010-10-06 2016-10-04 Taris Biomedical Llc Implantable drug delivery device with bladder retention feature
US8690840B2 (en) 2010-10-06 2014-04-08 Taris Biomedical, Inc. Time-selective bioresorbable or collapsible drug delivery systems and methods
US9114111B2 (en) * 2011-01-10 2015-08-25 Allergan, Inc. Methods for sustained treatment of bladder pain and irritative voiding
WO2012106714A1 (en) 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled release of low solubility drug
US8685106B2 (en) 2011-11-15 2014-04-01 Abraham Lin Method of a pharmaceutical delivery system for use within a joint replacement
EP2782632B1 (en) * 2011-11-21 2016-10-19 Incube Labs, LLC Myocardial drug delivery apparatus and methods
WO2013112734A1 (en) * 2012-01-24 2013-08-01 The Methodist Hospital Research Institute Sustained drug delivery from solid implants with nanochannel membranes
US20130289389A1 (en) 2012-04-26 2013-10-31 Focal Therapeutics Surgical implant for marking soft tissue
CA2872092C (en) 2012-04-30 2021-02-16 Taris Biomedical, Inc. Methods for treatment of pelvic pain and/or comorbid conditions
US20140012180A1 (en) * 2012-05-01 2014-01-09 Nidus Medical, Llc Peritoneal drain and infusion
US10058688B2 (en) 2012-05-09 2018-08-28 Massachusetts Institute Of Technology Medicament, method, and drug delivery device for treatment of ovarian cancer
RU2651128C2 (ru) * 2012-05-19 2018-04-18 ТАРИС Биомедикал ЛЛК Имплантируемое урологическое устройство с улучшенной характеристикой извлечения
KR102383496B1 (ko) 2012-08-31 2022-04-08 타리스 바이오메디컬 엘엘씨 젬시타빈을 포함하는 전립선 질환의 치료를 위한 약물 전달 시스템과 방법
RU2657591C2 (ru) 2012-08-31 2018-06-14 ТАРИС Биомедикал ЛЛК Способ лечения рака мочевого пузыря оксалиплатином, соответствующее устройство его доставки, способ и устройство его введения
MX379066B (es) 2012-09-18 2025-03-04 Taris Biomedical Llc Sistemas de administracion de farmaco y metodos para el tratamiento de la disfuncion miccional de la vejiga y otros trastornos del tracto urinario inferior.
JP2016508842A (ja) * 2013-03-05 2016-03-24 タリス バイオメディカル エルエルシー 装置の開口部を通じて制御された薬物放出のための薬物送達装置及び方法
EP2968120A1 (en) 2013-03-15 2016-01-20 TARIS Biomedical LLC Drug delivery devices and methods for drug delivery
SG11201507294WA (en) 2013-03-15 2015-10-29 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
JP5408682B1 (ja) * 2013-06-28 2014-02-05 ガデリウス・メディカル株式会社 ステントキット
WO2015026813A1 (en) 2013-08-19 2015-02-26 Taris Biomedical Llc Multi-unit drug delivery devices and methods
SE539540C2 (sv) * 2013-09-12 2017-10-10 Qpharma Ab Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar
KR20160083061A (ko) 2013-11-05 2016-07-11 타리스 바이오메디컬 엘엘씨 삼투 약물 전달 디바이스들, 키트, 및 방법들
HRP20251264T1 (hr) 2014-03-06 2025-12-05 Taris Biomedical Llc Sustavi za primjenu lijeka i metode za liječenje karcinoma mokraćnog mjehura gemcitabinom
KR102391761B1 (ko) 2014-06-26 2022-04-27 타리스 바이오메디컬 엘엘씨 탄성 폴리머-약물 매트릭스 시스템을 포함하는 방광내 약물 전달 장치 및 방법
WO2016014990A1 (en) * 2014-07-25 2016-01-28 Focal Therapeutics, Inc. Implantable devices and techniques for oncoplastic surgery
CN106573133B (zh) * 2014-08-19 2020-03-03 加利福尼亚大学董事会 用于局部药物递送的植入物及其使用方法
JP6743041B2 (ja) 2015-03-30 2020-08-19 タリス バイオメディカル エルエルシー 上部尿路への薬剤の局所的な送達装置及び方法
WO2016172704A1 (en) 2015-04-23 2016-10-27 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
WO2017132372A1 (en) 2016-01-26 2017-08-03 Taris Biomedical Llc Multi-lumen drug delivery devices
WO2017151983A1 (en) 2016-03-02 2017-09-08 Taris Biomedical Llc Osmotic drug delivery devices and methods of making osmotic drug delivery devices
FR3059553B1 (fr) 2016-12-07 2021-04-23 Univ Grenoble Alpes Dispositif implantable
LT3432970T (lt) 2017-02-01 2021-05-10 Taris Biomedical Llc In vivo vaistų vartojimo įtaisai
EP3600244A1 (en) * 2017-03-23 2020-02-05 Particle Sciences, Inc. Implantable and removable drug delivery device
US11541015B2 (en) 2017-05-17 2023-01-03 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
IL301683B2 (en) 2017-05-17 2025-02-01 Massachusetts Inst Technology Self-healing systems and related components and methods
WO2019023388A1 (en) 2017-07-25 2019-01-31 Taris Biomedical Llc METHODS OF TREATING TUMOR METASTASIS
PE20210041A1 (es) 2017-11-08 2021-01-08 Taris Biomedical Llc Metodos de tratamiento y terapia de mantenimiento para el cancer de vejiga con gemcitabina
EP3793667A1 (en) 2018-05-17 2021-03-24 Massachusetts Institute of Technology Systems for electrical stimulation
US20190365645A1 (en) * 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
CA3107461A1 (en) 2018-08-01 2020-02-06 Taris Biomedical Llc Methods of treating overactive bladder using trospium
CN117982783A (zh) * 2018-11-09 2024-05-07 塔里斯生物医药公司 用于将药物局部递送到上尿道的药物递送装置和系统
EP3952973B1 (en) 2019-06-13 2023-06-07 Hollister Incorporated Reusable urinary catheter products
AU2020304005B2 (en) 2019-06-25 2025-12-04 Hollister Incorporated Reusable urinary catheter products
KR102281386B1 (ko) * 2019-09-03 2021-07-23 인제대학교 산학협력단 요도 협착 억제장치
US11890438B1 (en) * 2019-09-12 2024-02-06 Cochlear Limited Therapeutic substance delivery
EP4041189B1 (en) 2019-10-07 2025-09-17 Oak Crest Institute of Science Orally implantable drug delivery device
AU2020391230A1 (en) 2019-11-27 2022-06-09 Oak Crest Institute Of Science Sustained release drug delivery device
US11338119B2 (en) 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11173291B2 (en) 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US20250001070A1 (en) * 2021-11-10 2025-01-02 Terumo Kabushiki Kaisha Administration device
JPWO2023100571A1 (enExample) * 2021-11-30 2023-06-08
EP4448543A1 (en) 2022-01-06 2024-10-23 Oak Crest Institute of Science Subdermal implant for sustained drug delivery
US12426818B2 (en) 2022-06-08 2025-09-30 Bright Uro, Inc. Packaging assembly and method of preparing sensing device for insertion into a body cavity to preserve sterility
WO2023239883A2 (en) 2022-06-08 2023-12-14 Bright Uro Inc. Systems and methods for urological sensing
CN121038778A (zh) 2023-04-19 2025-11-28 橡冠科学研究院 阴道药物递送装置
CN120052794B (zh) * 2025-04-24 2025-07-25 湖北大学 一种多靶点释药的磁驱动胶囊机器人

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3089815A (en) 1951-10-11 1963-05-14 Lieb Hans Injectable pharmaceutical preparation, and a method of making same
NL105769C (enExample) * 1960-02-27
GB1166613A (en) * 1965-10-07 1969-10-08 Hylton Frederick Grif Sheppard Intrauterine Contraceptives
US3425411A (en) * 1966-05-19 1969-02-04 Ralph R Robinson Intra-uterine device
US3312214A (en) * 1966-06-06 1967-04-04 Burdick Charles Lalor Intra-uterine device
US3457915A (en) * 1966-08-10 1969-07-29 Frank R Eshelman Intrauterine device
US3854480A (en) 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3789838A (en) * 1971-02-19 1974-02-05 E Fournier Force transmitting intrauterine device
US4016251A (en) 1972-08-17 1977-04-05 Alza Corporation Vaginal drug dispensing device
US3888975A (en) 1972-12-27 1975-06-10 Alza Corp Erodible intrauterine device
US3901232A (en) 1973-10-26 1975-08-26 Alza Corp Integrated device for administering beneficial drug at programmed rate
US3935860A (en) 1974-08-21 1976-02-03 Alza Corporation Intrauterine device with restrictor for maintaining device in uterine cavity
CH583552A5 (enExample) * 1975-04-23 1977-01-14 Akad Wroclawiu Med
US4326552A (en) 1979-01-23 1982-04-27 Ingo Bleckmann Heater for heating flows of fluid and dishwashing machine provided therewith
US4235236A (en) 1979-02-12 1980-11-25 Alza Corporation Device for dispensing drug by combined diffusional and osmotic operations
US4392848A (en) 1979-06-25 1983-07-12 The Procter & Gamble Company Catheterization
GB2079158B (en) 1980-06-09 1985-01-09 Ahi Operations Ltd Intra-vaginal devices
US4475916A (en) 1982-03-18 1984-10-09 Merck & Co., Inc. Osmotic drug delivery system
US4629449A (en) 1982-07-29 1986-12-16 Alza Corporation Vaginal dispenser for dispensing beneficial hormone
US5366738A (en) 1982-07-29 1994-11-22 Merck & Co., Inc. Controlled release drug dispersion delivery device
US4655219A (en) 1983-07-22 1987-04-07 American Hospital Supply Corporation Multicomponent flexible grasping device
DE3332156A1 (de) 1983-09-06 1985-03-21 Peter 6000 Frankfurt Prezelj Nasenspange
GB8328916D0 (en) 1983-10-28 1983-11-30 Castex Prod Pharmaceutical pellet
GB8403138D0 (en) 1984-02-07 1984-03-14 Graham N B Sustained release of active ingredient
NZ207341A (en) 1984-03-01 1988-02-29 Harvey Alex Ind Ltd Device containing chemical impregnants for insertion into a body cavity of an animal
US4968507A (en) * 1984-06-20 1990-11-06 Merck & Co., Inc. Controlled porosity osmotic pump
CH667209A5 (de) 1985-07-02 1988-09-30 Sulzer Ag Medizinische depotsonde.
US4871542A (en) 1987-04-30 1989-10-03 Ferring Service Center, N.V. Method and apparatus useful for delivering medicinal compositions into the bladder and urinary tract
BE1002600A3 (fr) * 1988-11-23 1991-04-09 Wildemeersch Dirk Dispositif intra-uterin perfectionne.
NZ228382A (en) * 1989-03-17 1992-08-26 Carter Holt Harvey Plastic Pro Drug administering coil-like device for insertion in body cavity of animal
US5545208A (en) 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
WO1993006792A1 (en) 1991-10-04 1993-04-15 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
EP0607321A1 (en) 1991-10-10 1994-07-27 Alza Corporation Osmotic drug delivery devices with hydrophobic wall materials
US5441550A (en) 1992-03-26 1995-08-15 The University Of Tennessee Research Corporation Post-treatment of laminated nonwoven cellulosic fiber webs
US5499997A (en) 1992-04-10 1996-03-19 Sharpe Endosurgical Corporation Endoscopic tenaculum surgical instrument
ES2150427T3 (es) 1992-06-02 2000-12-01 Bard Inc C R Procedimiento y dispositivo de implante para el suministro de farmacos a largo plazo.
US5368588A (en) * 1993-02-26 1994-11-29 Bettinger; David S. Parenteral fluid medication reservoir pump
US5523092A (en) 1993-04-14 1996-06-04 Emory University Device for local drug delivery and methods for using the same
US5516522A (en) 1994-03-14 1996-05-14 Board Of Supervisors Of Louisiana State University Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same
IL116433A (en) 1994-12-19 2002-02-10 Galen Chemicals Ltd INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS
GB9522403D0 (en) 1995-11-01 1996-01-03 Hoechst Roussel Ltd Intravaginal drug delivery device
US6171298B1 (en) * 1996-05-03 2001-01-09 Situs Corporation Intravesical infuser
US5869081A (en) 1996-06-28 1999-02-09 The Population Council Progesterone vaginal ring for treatment of infertility
US5797898A (en) 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US5972372A (en) 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
ZA9710342B (en) * 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US5868719A (en) * 1997-01-15 1999-02-09 Boston Scientific Corporation Drug delivery balloon catheter device
US5830230A (en) 1997-03-07 1998-11-03 Micro Therapeutics, Inc. Method of intracranial vascular embolotherapy using self anchoring coils
WO1998043555A1 (en) 1997-04-03 1998-10-08 Point Biomedical Corporation Intravesical drug delivery system
IL123813A0 (en) 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
NZ501236A (en) 1997-05-07 2002-02-01 Galen Chemicals Ltd Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors in a polymer matrix and surrounded by a sheath
AU723217B2 (en) 1997-05-28 2000-08-24 Interag Intra-vaginal device for pigs
US6197327B1 (en) 1997-06-11 2001-03-06 Umd, Inc. Device and method for treatment of dysmenorrhea
US6039968A (en) 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6267761B1 (en) 1997-09-09 2001-07-31 Sherwood Services Ag Apparatus and method for sealing and cutting tissue
WO1999018884A1 (en) 1997-10-10 1999-04-22 Duirs Nz Limited Drug delivery system
US6749617B1 (en) 1997-11-04 2004-06-15 Scimed Life Systems, Inc. Catheter and implants for the delivery of therapeutic agents to tissues
AU751861B2 (en) * 1998-02-23 2002-08-29 Massachusetts Institute Of Technology Biodegradable shape memory polymers
US6183461B1 (en) * 1998-03-11 2001-02-06 Situs Corporation Method for delivering a medication
US6482837B1 (en) 1998-04-24 2002-11-19 University Of Rochester Antimuscarinic compounds and methods for treatment of bladder diseases
US6159143A (en) 1998-06-17 2000-12-12 Scimed Life Systems, Inc. Method and device for delivery of therapeutic agents in conjunction with isotope seed placement
US6464999B1 (en) 1998-06-17 2002-10-15 Galt Incorporated Bioadhesive medical devices
WO2000040234A1 (en) 1999-01-06 2000-07-13 Richard Henry Topical anesthesia of the urinary bladder
US6293923B1 (en) 1999-03-15 2001-09-25 Innoventions, Inc. Intravesicular balloon
US6083933A (en) 1999-04-19 2000-07-04 Stellar International Inc. Treatment of cystitis-like symptoms with chondroitin sulfate following administration of a challenge solution
US6139535A (en) 1999-05-27 2000-10-31 Situs Corporation Method and apparatus for placement and activation of a medical device within a body cavity
EP1690527B1 (en) 1999-11-17 2015-01-07 Boston Scientific Limited Microfabricated devices for the delivery of molecules into a carrier fluid
CA2393603C (en) 1999-12-10 2010-09-21 Massachusetts Institute Of Technology Microchip devices for delivery of molecules and methods of fabrication thereof
US20050238733A1 (en) 2000-01-05 2005-10-27 Richard Henry Topical anesthesia of the urinary bladder
US6753011B2 (en) 2000-01-14 2004-06-22 Osmotica Corp Combined diffusion/osmotic pumping drug delivery system
US6379382B1 (en) 2000-03-13 2002-04-30 Jun Yang Stent having cover with drug delivery capability
US6682473B1 (en) 2000-04-14 2004-01-27 Solace Therapeutics, Inc. Devices and methods for attenuation of pressure waves in the body
US7470228B2 (en) 2000-04-14 2008-12-30 Attenuex Technologies, Inc. Method of treating benign hypertrophy of the prostate
US7232421B1 (en) * 2000-05-12 2007-06-19 C. R. Bard, Inc. Agent delivery systems
US6398718B1 (en) 2000-06-15 2002-06-04 Innoventions, Inc. Intravesicular device
US7521064B2 (en) 2000-08-24 2009-04-21 Saxena Brij B Non-hormonal vaginal contraceptive
US6752829B2 (en) 2001-01-30 2004-06-22 Scimed Life Systems, Inc. Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same
NZ528377A (en) 2001-03-27 2005-05-27 Galen Chemicals Ltd Intravaginal drug delivery devices for the administration of an antimicrobial agent
WO2002096389A1 (en) 2001-05-30 2002-12-05 Microchips, Inc. Conformal coated microchip reservoir devices
US7438701B2 (en) 2001-07-26 2008-10-21 Durect Corporation Local concentration management system
US20030118649A1 (en) 2001-10-04 2003-06-26 Jinming Gao Drug delivery devices and methods
US7722894B2 (en) 2001-10-22 2010-05-25 Massachusetts Institute Of Technology Biodegradable polymer
US7005138B2 (en) 2001-12-21 2006-02-28 Duramed Pharmaceuticals, Inc. Method of systematically delivering SSRIs
US7473273B2 (en) * 2002-01-22 2009-01-06 Medtronic Vascular, Inc. Stent assembly with therapeutic agent exterior banding
US8685427B2 (en) * 2002-07-31 2014-04-01 Boston Scientific Scimed, Inc. Controlled drug delivery
GB2385273B (en) 2002-02-13 2004-05-26 Deborah Huang Drug delivery device
US6899890B2 (en) 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
EP1400258A1 (en) 2002-09-18 2004-03-24 Schering Oy Pharmaceutical composition delivery device and its manufacturing process
DE10247689A1 (de) 2002-10-12 2004-04-22 Martin Rahe Implantat in der Harnblase
US7504387B2 (en) 2002-10-16 2009-03-17 Arthrodynamic Technologies, Animal Health Division, Inc. Glycosaminoglycan composition and method for treatment and prevention of interstitial cystitis
AU2003301669B2 (en) 2002-10-22 2009-04-30 Biomerix Corporation Method and system for intravesicular delivery of the therapeutic agents
US9440302B2 (en) * 2002-12-16 2016-09-13 The Regents Of The University Of Michigan Assembly and planar structure for use therein which is expandable into a 3-D structure such as a stent and device for making the planar structure
EP1581285B1 (en) 2002-12-23 2009-02-25 Medtronic, Inc. Drug solution density adjustment systems and methods
US20050234431A1 (en) 2004-02-10 2005-10-20 Williams Michael S Intravascular delivery system for therapeutic agents
EP2813231A1 (en) 2004-01-28 2014-12-17 The Regents of The University of California Novel interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis
US7647112B2 (en) 2004-02-11 2010-01-12 Ethicon, Inc. System and method for selectively stimulating different body parts
WO2005115245A1 (en) 2004-05-28 2005-12-08 Dynaventions Inc. Intravesicular device
EP1858454A1 (en) * 2005-03-01 2007-11-28 Columna Pty Ltd Intervertebral disc restoration
WO2006113913A2 (en) 2005-04-20 2006-10-26 Cook Incorporated Joint for medical device delivery system
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
DK1933810T3 (da) 2005-08-11 2013-01-28 Childrens Medical Center Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde
US20100003297A1 (en) 2005-08-11 2010-01-07 Massachusetts Institute Of Technology Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues
US20070172508A1 (en) 2006-01-26 2007-07-26 Paul Zupkas Transluminal drug delivery methods and devices
US20070172507A1 (en) 2006-01-26 2007-07-26 Paul Zupkas Transluminal drug delivery methods and devices
BRPI0709344A2 (pt) 2006-03-20 2011-07-12 Duramed Pharmaceuticals Inc anel intravaginal comprimido flexìvel, seu uso e processo de preparação, método de fornecer um agente ativo, kit terapêutico e produto
US20070255222A1 (en) * 2006-03-27 2007-11-01 Changqing Li Catheter assembly including internal bolster
ES2640458T3 (es) 2006-03-31 2017-11-03 Mati Therapeutics Inc. Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa
US7824383B2 (en) 2006-06-16 2010-11-02 Family Health International Vaginal drug delivery system and method
EP2096983A2 (en) 2006-09-28 2009-09-09 Medvision Inc. Examination device
SG195525A1 (en) 2007-06-26 2013-12-30 Warner Chilcott Co Llc Intravaginal drug delivery devices for the delivery of macromolecules and water-soluble drugs
US8303536B2 (en) 2007-08-30 2012-11-06 Sunstorm Research Corp. Implantable delivery device
DK2231254T3 (da) 2007-12-11 2014-07-21 Massachusetts Inst Technology Implanterbar lægemiddelafgivelsesindretning

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US12296127B2 (en) 2025-05-13
US11612718B2 (en) 2023-03-28
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US20090149833A1 (en) 2009-06-11
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