JP2011505846A5 - - Google Patents
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- JP2011505846A5 JP2011505846A5 JP2010538304A JP2010538304A JP2011505846A5 JP 2011505846 A5 JP2011505846 A5 JP 2011505846A5 JP 2010538304 A JP2010538304 A JP 2010538304A JP 2010538304 A JP2010538304 A JP 2010538304A JP 2011505846 A5 JP2011505846 A5 JP 2011505846A5
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- Prior art keywords
- compound
- molecule
- disease
- growth factor
- kinase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001413 amino acids Chemical group 0.000 claims 8
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
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- PAEZRCINULFAGO-OAQYLSRUSA-N (R)-homocamptothecin Chemical compound CC[C@@]1(O)CC(=O)OCC(C2=O)=C1C=C1N2CC2=CC3=CC=CC=C3N=C21 PAEZRCINULFAGO-OAQYLSRUSA-N 0.000 claims 1
- LGZKGOGODCLQHG-CYBMUJFWSA-N 5-[(2r)-2-hydroxy-2-(3,4,5-trimethoxyphenyl)ethyl]-2-methoxyphenol Chemical compound C1=C(O)C(OC)=CC=C1C[C@@H](O)C1=CC(OC)=C(OC)C(OC)=C1 LGZKGOGODCLQHG-CYBMUJFWSA-N 0.000 claims 1
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- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US882507P | 2007-12-20 | 2007-12-20 | |
| PCT/CA2008/002269 WO2009079790A1 (en) | 2007-12-20 | 2008-12-19 | Polypeptide-nucleic acid conjugates and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011505846A JP2011505846A (ja) | 2011-03-03 |
| JP2011505846A5 true JP2011505846A5 (enExample) | 2012-02-09 |
Family
ID=40800623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538304A Pending JP2011505846A (ja) | 2007-12-20 | 2008-12-19 | ポリペプチド−核酸コンジュゲートおよびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20110039785A1 (enExample) |
| EP (1) | EP2235175A4 (enExample) |
| JP (1) | JP2011505846A (enExample) |
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| WO2019037133A1 (zh) * | 2017-08-25 | 2019-02-28 | 深圳市博奥康生物科技有限公司 | 靶向沉默APP的shRNA |
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| CN111208284B (zh) * | 2018-11-22 | 2021-08-24 | 北京大学 | 糖代谢标记探针、包含其的试剂盒及其应用 |
| MD3989962T2 (ro) | 2019-06-28 | 2025-12-31 | Intrabio Ltd Gb | Terapie combinată cu acetil-leucină și miglustat pentru tratamentul unei boli de depozitare lizozomală |
| KR102320650B1 (ko) * | 2019-10-16 | 2021-11-04 | 주식회사 시선테라퓨틱스 | 혈뇌장벽 투과능을 가지는 펩티드 핵산 복합체 및 이를 포함하는 조성물 |
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| JP2024503711A (ja) * | 2021-01-18 | 2024-01-26 | イェダ リサーチ アンド デベロップメント カンパニー リミテッド | 修飾ｍｉＲ－１３５、そのコンジュゲートおよびその使用 |
| CN117440816A (zh) * | 2021-01-18 | 2024-01-23 | 耶达研究及发展有限公司 | 修饰的mir-135、其缀合形式及其用途 |
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| AU2023331232A1 (en) * | 2022-08-22 | 2025-03-27 | University Of Tartu | Brain penetrating peptides and methods of use thereof |
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| JP2009507852A (ja) * | 2005-09-08 | 2009-02-26 | エムディーアールエヌエー，インコーポレイテッド | リボ核酸の細胞への送達用医薬組成物 |
| CA2688344C (en) * | 2007-05-29 | 2019-09-03 | Angiochem, Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
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2008
- 2008-12-19 EP EP08865493A patent/EP2235175A4/en not_active Withdrawn
- 2008-12-19 RU RU2010129761/10A patent/RU2010129761A/ru not_active Application Discontinuation
- 2008-12-19 JP JP2010538304A patent/JP2011505846A/ja active Pending
- 2008-12-19 WO PCT/CA2008/002269 patent/WO2009079790A1/en not_active Ceased
- 2008-12-19 BR BRPI0821310-0A patent/BRPI0821310A2/pt not_active IP Right Cessation
- 2008-12-19 AU AU2008340943A patent/AU2008340943A1/en not_active Abandoned
- 2008-12-19 CA CA2709635A patent/CA2709635A1/en not_active Abandoned
- 2008-12-19 MX MX2010006925A patent/MX2010006925A/es not_active Application Discontinuation
- 2008-12-19 US US12/808,439 patent/US20110039785A1/en not_active Abandoned
- 2008-12-19 CN CN2008801270674A patent/CN101946001A/zh active Pending
-
2010
- 2010-06-30 ZA ZA2010/04609A patent/ZA201004609B/en unknown
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