JP2011505122A5 - - Google Patents
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- Publication number
- JP2011505122A5 JP2011505122A5 JP2010533319A JP2010533319A JP2011505122A5 JP 2011505122 A5 JP2011505122 A5 JP 2011505122A5 JP 2010533319 A JP2010533319 A JP 2010533319A JP 2010533319 A JP2010533319 A JP 2010533319A JP 2011505122 A5 JP2011505122 A5 JP 2011505122A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- microarray
- genomic
- amplified
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004414 DNA Proteins 0.000 claims description 170
- 238000000034 method Methods 0.000 claims description 118
- 239000000523 sample Substances 0.000 claims description 86
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 80
- 230000003321 amplification Effects 0.000 claims description 79
- 238000000018 DNA microarray Methods 0.000 claims description 76
- 210000004027 cell Anatomy 0.000 claims description 71
- 238000009396 hybridization Methods 0.000 claims description 64
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 50
- 230000005945 translocation Effects 0.000 claims description 33
- 238000002493 microarray Methods 0.000 claims description 28
- 230000008707 rearrangement Effects 0.000 claims description 28
- 201000010099 disease Diseases 0.000 claims description 27
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 27
- 239000013074 reference sample Substances 0.000 claims description 27
- 206010025323 Lymphomas Diseases 0.000 claims description 24
- 238000002372 labelling Methods 0.000 claims description 22
- 230000008711 chromosomal rearrangement Effects 0.000 claims description 21
- 210000000349 chromosome Anatomy 0.000 claims description 21
- 208000032839 leukemia Diseases 0.000 claims description 20
- 210000004881 tumor cell Anatomy 0.000 claims description 20
- 208000034951 Genetic Translocation Diseases 0.000 claims description 16
- 239000000203 mixture Substances 0.000 claims description 14
- 108700005091 Immunoglobulin Genes Proteins 0.000 claims description 12
- 206010028980 Neoplasm Diseases 0.000 claims description 12
- 201000011510 cancer Diseases 0.000 claims description 12
- 230000008521 reorganization Effects 0.000 claims description 11
- 230000002759 chromosomal effect Effects 0.000 claims description 10
- 239000007850 fluorescent dye Substances 0.000 claims description 8
- 238000012217 deletion Methods 0.000 claims description 7
- 230000037430 deletion Effects 0.000 claims description 7
- 238000003499 nucleic acid array Methods 0.000 claims description 6
- 239000012472 biological sample Substances 0.000 claims description 5
- 238000004458 analytical method Methods 0.000 claims description 4
- 238000001514 detection method Methods 0.000 claims description 4
- 208000011691 Burkitt lymphomas Diseases 0.000 claims description 2
- 206010061764 Chromosomal deletion Diseases 0.000 claims description 2
- 208000035970 Chromosome Breakpoints Diseases 0.000 claims description 2
- 208000036086 Chromosome Duplication Diseases 0.000 claims description 2
- 108091034117 Oligonucleotide Proteins 0.000 claims description 2
- 238000003556 assay Methods 0.000 claims description 2
- 238000004590 computer program Methods 0.000 claims description 2
- 238000003745 diagnosis Methods 0.000 claims description 2
- 238000004949 mass spectrometry Methods 0.000 claims description 2
- 230000001404 mediated effect Effects 0.000 claims description 2
- 238000004393 prognosis Methods 0.000 claims description 2
- 238000012163 sequencing technique Methods 0.000 claims description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98657607P | 2007-11-08 | 2007-11-08 | |
| US60/986,576 | 2007-11-08 | ||
| PCT/US2008/083014 WO2009062166A2 (en) | 2007-11-08 | 2008-11-10 | Dna microarray based identification and mapping of balanced translocation breakpoints |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011505122A JP2011505122A (ja) | 2011-02-24 |
| JP2011505122A5 true JP2011505122A5 (enExample) | 2011-12-22 |
| JP5421278B2 JP5421278B2 (ja) | 2014-02-19 |
Family
ID=40626471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010533319A Expired - Fee Related JP5421278B2 (ja) | 2007-11-08 | 2008-11-10 | 平衡転座切断点のｄｎａマイクロアレイベースの同定とマッピング |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110021371A1 (enExample) |
| EP (1) | EP2217921A4 (enExample) |
| JP (1) | JP5421278B2 (enExample) |
| KR (1) | KR20100097139A (enExample) |
| CN (1) | CN101918831B (enExample) |
| AU (1) | AU2008323649A1 (enExample) |
| BR (1) | BRPI0820272A2 (enExample) |
| CA (1) | CA2704625A1 (enExample) |
| MX (1) | MX2010005060A (enExample) |
| WO (1) | WO2009062166A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2147981A1 (en) * | 2008-07-25 | 2010-01-27 | Biotype AG | Kit and method for evaluating detection properties in amplification reactions |
| ITMI20091007A1 (it) | 2009-06-09 | 2010-12-10 | Giovanni Porta | Metodo di monitoraggio e trattamento |
| AU2010298000A1 (en) * | 2009-09-25 | 2012-04-05 | Signature Genomics Laboratories Llc | Multiplex (+/-) stranded arrays and assays for detecting chromosomal abnormalities associated with cancer and other diseases |
| WO2012159069A1 (en) * | 2011-05-19 | 2012-11-22 | University Of Utah Research Foundation | Methods and compostions for the detection of balanced reciprocal translocations/rearrangements |
| WO2013033169A1 (en) * | 2011-08-31 | 2013-03-07 | Sanofi | Methods of identifying genomic translocations associated with cancer |
| FR3010530B1 (fr) * | 2013-09-11 | 2015-10-09 | Univ Rouen | Methode de diagnostic des hemopathies malignes et kit associe |
| CN103704205B (zh) * | 2014-01-15 | 2015-09-23 | 山东大学 | 一种含微量稀土的牛精液冷冻稀释液及其应用 |
| US10443090B2 (en) | 2014-11-25 | 2019-10-15 | Electronics And Telecommunications Research Institute | Method and apparatus for detecting translocation |
| JP2018516577A (ja) * | 2015-05-29 | 2018-06-28 | アルターゴン エスアー | 高感度ｃｇｈ解析のための方法、支持体及びキット |
| CN105044168A (zh) * | 2015-06-03 | 2015-11-11 | 福建医科大学 | 基于氟代核酸探针的双通道传感器检测急早幼粒PML/RARα基因序列的方法 |
| WO2020225551A1 (en) * | 2019-05-08 | 2020-11-12 | Oxford BioDynamics PLC | Chromosome conformation markers of prostate cancer and lymphoma |
| CN112669902B (zh) * | 2021-03-16 | 2021-06-04 | 北京贝瑞和康生物技术有限公司 | 检测基因组结构变异的方法、计算设备和存储介质 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830645A (en) * | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US6251601B1 (en) * | 1999-02-02 | 2001-06-26 | Vysis, Inc. | Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays |
| WO2002093130A2 (en) * | 2001-05-14 | 2002-11-21 | Cancer Genetics, Inc. | Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (fish) |
| US20050159378A1 (en) * | 2001-05-18 | 2005-07-21 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA) |
| US7198897B2 (en) * | 2001-12-19 | 2007-04-03 | Brandeis University | Late-PCR |
| US20030124539A1 (en) * | 2001-12-21 | 2003-07-03 | Affymetrix, Inc. A Corporation Organized Under The Laws Of The State Of Delaware | High throughput resequencing and variation detection using high density microarrays |
| US20040097711A1 (en) * | 2002-03-12 | 2004-05-20 | Henry Yue | Immunoglobulin superfamily proteins |
| US20050112689A1 (en) * | 2003-04-04 | 2005-05-26 | Robert Kincaid | Systems and methods for statistically analyzing apparent CGH data anomalies and plotting same |
| AU2003901671A0 (en) * | 2003-04-02 | 2003-05-01 | The University Of Adelaide | Comparative genomic hybridization |
| DE102005028381A1 (de) * | 2005-06-20 | 2006-12-28 | Wella Ag | Produktabgabesystem zum Versprühen haarkerantinreduzierende oder oxidierende Wirkstoffe enthaltender Zusammensetzungen |
| DE102005031734A1 (de) * | 2005-07-07 | 2007-01-18 | GM Global Technology Operations, Inc., Detroit | Verfahren zur Berechnung des Unterdruckes im Bremskraftverstärker eines Fahrzeugs mit Otto-Motor |
| GB0516797D0 (en) * | 2005-08-16 | 2005-09-21 | Oxford Gene Tech Ip Ltd | CGH method |
| US8076074B2 (en) * | 2005-11-29 | 2011-12-13 | Quest Diagnostics Investments Incorporated | Balanced translocation in comparative hybridization |
| US8058055B2 (en) * | 2006-04-07 | 2011-11-15 | Agilent Technologies, Inc. | High resolution chromosomal mapping |
-
2008
- 2008-11-10 AU AU2008323649A patent/AU2008323649A1/en not_active Abandoned
- 2008-11-10 CN CN200880124084.2A patent/CN101918831B/zh not_active Expired - Fee Related
- 2008-11-10 JP JP2010533319A patent/JP5421278B2/ja not_active Expired - Fee Related
- 2008-11-10 US US12/742,237 patent/US20110021371A1/en not_active Abandoned
- 2008-11-10 KR KR1020107012586A patent/KR20100097139A/ko not_active Ceased
- 2008-11-10 MX MX2010005060A patent/MX2010005060A/es not_active Application Discontinuation
- 2008-11-10 BR BRPI0820272-9A patent/BRPI0820272A2/pt not_active IP Right Cessation
- 2008-11-10 EP EP08847203A patent/EP2217921A4/en not_active Withdrawn
- 2008-11-10 CA CA2704625A patent/CA2704625A1/en not_active Abandoned
- 2008-11-10 WO PCT/US2008/083014 patent/WO2009062166A2/en not_active Ceased
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