JP2011502173A5 - - Google Patents
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- Publication number
- JP2011502173A5 JP2011502173A5 JP2010532377A JP2010532377A JP2011502173A5 JP 2011502173 A5 JP2011502173 A5 JP 2011502173A5 JP 2010532377 A JP2010532377 A JP 2010532377A JP 2010532377 A JP2010532377 A JP 2010532377A JP 2011502173 A5 JP2011502173 A5 JP 2011502173A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery system
- transdermal delivery
- drugs
- agent
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000037317 transdermal delivery Effects 0.000 claims 22
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 14
- 239000003814 drug Substances 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 12
- 229940079593 drug Drugs 0.000 claims 11
- 239000012867 bioactive agent Substances 0.000 claims 8
- 239000002202 Polyethylene glycol Substances 0.000 claims 7
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 7
- 229920001223 polyethylene glycol Polymers 0.000 claims 7
- 229960004889 salicylic acid Drugs 0.000 claims 7
- -1 aliphatic ester Chemical class 0.000 claims 5
- 150000002148 esters Chemical class 0.000 claims 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 4
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 4
- 229940088597 hormone Drugs 0.000 claims 4
- 239000005556 hormone Substances 0.000 claims 4
- 239000003961 penetration enhancing agent Substances 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 3
- 239000013543 active substance Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 230000035515 penetration Effects 0.000 claims 3
- 210000003491 skin Anatomy 0.000 claims 3
- 239000007921 spray Substances 0.000 claims 3
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 239000003098 androgen Substances 0.000 claims 2
- 230000003474 anti-emetic effect Effects 0.000 claims 2
- 239000000935 antidepressant agent Substances 0.000 claims 2
- 229940005513 antidepressants Drugs 0.000 claims 2
- 239000002111 antiemetic agent Substances 0.000 claims 2
- 239000002249 anxiolytic agent Substances 0.000 claims 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 229940011871 estrogen Drugs 0.000 claims 2
- 239000000262 estrogen Substances 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 239000000583 progesterone congener Substances 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 229960003604 testosterone Drugs 0.000 claims 2
- 230000005186 women's health Effects 0.000 claims 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 229940122815 Aromatase inhibitor Drugs 0.000 claims 1
- 208000009079 Bronchial Spasm Diseases 0.000 claims 1
- 208000014181 Bronchial disease Diseases 0.000 claims 1
- 206010006482 Bronchospasm Diseases 0.000 claims 1
- 229940127291 Calcium channel antagonist Drugs 0.000 claims 1
- NMJREATYWWNIKX-UHFFFAOYSA-N GnRH Chemical compound C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CC(C)C)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 NMJREATYWWNIKX-UHFFFAOYSA-N 0.000 claims 1
- 102000006771 Gonadotropins Human genes 0.000 claims 1
- 108010086677 Gonadotropins Proteins 0.000 claims 1
- 201000005569 Gout Diseases 0.000 claims 1
- 102000003710 Histamine H2 Receptors Human genes 0.000 claims 1
- 108090000050 Histamine H2 Receptors Proteins 0.000 claims 1
- 208000037147 Hypercalcaemia Diseases 0.000 claims 1
- 201000001431 Hyperuricemia Diseases 0.000 claims 1
- 206010058359 Hypogonadism Diseases 0.000 claims 1
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims 1
- 229940124091 Keratolytic Drugs 0.000 claims 1
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 claims 1
- 125000005907 alkyl ester group Chemical group 0.000 claims 1
- 239000013566 allergen Substances 0.000 claims 1
- 239000002269 analeptic agent Substances 0.000 claims 1
- 229940035676 analgesics Drugs 0.000 claims 1
- 238000009165 androgen replacement therapy Methods 0.000 claims 1
- 229940030486 androgens Drugs 0.000 claims 1
- 230000000954 anitussive effect Effects 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 230000000507 anthelmentic effect Effects 0.000 claims 1
- 229940124339 anthelmintic agent Drugs 0.000 claims 1
- 239000000921 anthelmintic agent Substances 0.000 claims 1
- 230000003255 anti-acne Effects 0.000 claims 1
- 239000004004 anti-anginal agent Substances 0.000 claims 1
- 230000001773 anti-convulsant effect Effects 0.000 claims 1
- 230000001430 anti-depressive effect Effects 0.000 claims 1
- 230000002686 anti-diuretic effect Effects 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 230000002682 anti-psoriatic effect Effects 0.000 claims 1
- 230000001754 anti-pyretic effect Effects 0.000 claims 1
- 229940124345 antianginal agent Drugs 0.000 claims 1
- 239000003416 antiarrhythmic agent Substances 0.000 claims 1
- 229940124350 antibacterial drug Drugs 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 239000001961 anticonvulsive agent Substances 0.000 claims 1
- 229940125714 antidiarrheal agent Drugs 0.000 claims 1
- 239000003793 antidiarrheal agent Substances 0.000 claims 1
- 229940124538 antidiuretic agent Drugs 0.000 claims 1
- 229960003965 antiepileptics Drugs 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 229940125715 antihistaminic agent Drugs 0.000 claims 1
- 239000002220 antihypertensive agent Substances 0.000 claims 1
- 229940030600 antihypertensive agent Drugs 0.000 claims 1
- 239000003430 antimalarial agent Substances 0.000 claims 1
- 229940005486 antimigraine preparations Drugs 0.000 claims 1
- 239000003908 antipruritic agent Substances 0.000 claims 1
- 239000000164 antipsychotic agent Substances 0.000 claims 1
- 229940005529 antipsychotics Drugs 0.000 claims 1
- 239000002221 antipyretic Substances 0.000 claims 1
- 229940125716 antipyretic agent Drugs 0.000 claims 1
- 239000003435 antirheumatic agent Substances 0.000 claims 1
- 239000003434 antitussive agent Substances 0.000 claims 1
- 229940124584 antitussives Drugs 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 230000000949 anxiolytic effect Effects 0.000 claims 1
- 229940005530 anxiolytics Drugs 0.000 claims 1
- 239000002830 appetite depressant Substances 0.000 claims 1
- 239000003886 aromatase inhibitor Substances 0.000 claims 1
- 239000002876 beta blocker Substances 0.000 claims 1
- 230000000975 bioactive effect Effects 0.000 claims 1
- 229960001948 caffeine Drugs 0.000 claims 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims 1
- 239000000480 calcium channel blocker Substances 0.000 claims 1
- 239000002368 cardiac glycoside Substances 0.000 claims 1
- 229940097217 cardiac glycoside Drugs 0.000 claims 1
- 239000002327 cardiovascular agent Substances 0.000 claims 1
- 229940125692 cardiovascular agent Drugs 0.000 claims 1
- 239000013522 chelant Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000000812 cholinergic antagonist Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003433 contraceptive agent Substances 0.000 claims 1
- 230000002254 contraceptive effect Effects 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 231100000433 cytotoxic Toxicity 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 239000000850 decongestant Substances 0.000 claims 1
- 229940124581 decongestants Drugs 0.000 claims 1
- 230000002950 deficient Effects 0.000 claims 1
- 239000002934 diuretic Substances 0.000 claims 1
- 229940030606 diuretics Drugs 0.000 claims 1
- 238000012377 drug delivery Methods 0.000 claims 1
- 229940072185 drug for treatment of tuberculosis Drugs 0.000 claims 1
- 239000003172 expectorant agent Substances 0.000 claims 1
- 230000003419 expectorant effect Effects 0.000 claims 1
- 229940066493 expectorants Drugs 0.000 claims 1
- 239000002622 gonadotropin Substances 0.000 claims 1
- 239000003933 gonadotropin antagonist Substances 0.000 claims 1
- 238000002657 hormone replacement therapy Methods 0.000 claims 1
- 230000000148 hypercalcaemia Effects 0.000 claims 1
- 208000030915 hypercalcemia disease Diseases 0.000 claims 1
- 239000003326 hypnotic agent Substances 0.000 claims 1
- 230000000147 hypnotic effect Effects 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000002917 insecticide Substances 0.000 claims 1
- 230000001530 keratinolytic effect Effects 0.000 claims 1
- 239000003589 local anesthetic agent Substances 0.000 claims 1
- 229960005015 local anesthetics Drugs 0.000 claims 1
- 239000002207 metabolite Substances 0.000 claims 1
- 229960001785 mirtazapine Drugs 0.000 claims 1
- RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical group C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 claims 1
- 229940035363 muscle relaxants Drugs 0.000 claims 1
- 239000003158 myorelaxant agent Substances 0.000 claims 1
- 239000000842 neuromuscular blocking agent Substances 0.000 claims 1
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- LPMXVESGRSUGHW-HBYQJFLCSA-N ouabain Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1C[C@@]2(O)CC[C@H]3[C@@]4(O)CC[C@H](C=5COC(=O)C=5)[C@@]4(C)C[C@@H](O)[C@@H]3[C@@]2(CO)[C@H](O)C1 LPMXVESGRSUGHW-HBYQJFLCSA-N 0.000 claims 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 claims 1
- 239000000575 pesticide Substances 0.000 claims 1
- 239000000186 progesterone Substances 0.000 claims 1
- 229960003387 progesterone Drugs 0.000 claims 1
- 239000002379 progesterone receptor modulator Substances 0.000 claims 1
- 239000003380 propellant Substances 0.000 claims 1
- 150000003180 prostaglandins Chemical class 0.000 claims 1
- 229940126409 proton pump inhibitor Drugs 0.000 claims 1
- 239000000612 proton pump inhibitor Substances 0.000 claims 1
- 239000003368 psychostimulant agent Substances 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229940095743 selective estrogen receptor modulator Drugs 0.000 claims 1
- 239000000333 selective estrogen receptor modulator Substances 0.000 claims 1
- 230000005586 smoking cessation Effects 0.000 claims 1
- 229930002534 steroid glycoside Natural products 0.000 claims 1
- 230000003637 steroidlike Effects 0.000 claims 1
- 210000000434 stratum corneum Anatomy 0.000 claims 1
- 229940124549 vasodilator Drugs 0.000 claims 1
- 239000003071 vasodilator agent Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98478707P | 2007-11-02 | 2007-11-02 | |
| US60/984,787 | 2007-11-02 | ||
| PCT/AU2008/001614 WO2009055860A1 (en) | 2007-11-02 | 2008-10-31 | Transdermal delivery system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011502173A JP2011502173A (ja) | 2011-01-20 |
| JP2011502173A5 true JP2011502173A5 (enExample) | 2011-12-08 |
| JP5737942B2 JP5737942B2 (ja) | 2015-06-17 |
Family
ID=40590452
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010532377A Expired - Fee Related JP5737942B2 (ja) | 2007-11-02 | 2008-10-31 | 経皮送達システム |
| JP2010532376A Ceased JP2011502172A (ja) | 2007-11-02 | 2008-10-31 | ホルモンおよびステロイド用の経皮送達システム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010532376A Ceased JP2011502172A (ja) | 2007-11-02 | 2008-10-31 | ホルモンおよびステロイド用の経皮送達システム |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US20100297032A1 (enExample) |
| EP (2) | EP2219603B1 (enExample) |
| JP (2) | JP5737942B2 (enExample) |
| KR (2) | KR20100094495A (enExample) |
| CN (2) | CN101883556B (enExample) |
| AU (2) | AU2008318283B2 (enExample) |
| BR (2) | BRPI0819235A2 (enExample) |
| CA (2) | CA2704116A1 (enExample) |
| DK (2) | DK2219603T3 (enExample) |
| EA (2) | EA019760B1 (enExample) |
| ES (2) | ES2494853T3 (enExample) |
| MX (2) | MX2010004789A (enExample) |
| NZ (2) | NZ585033A (enExample) |
| PL (2) | PL2214643T3 (enExample) |
| PT (2) | PT2214643E (enExample) |
| WO (2) | WO2009055859A1 (enExample) |
| ZA (1) | ZA201003553B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR068408A1 (es) * | 2007-09-14 | 2009-11-18 | Drugtech Corp | Pulverizacion de hormonas transdermicas |
| AR068409A1 (es) * | 2007-09-14 | 2009-11-18 | Drugtech Corp | Composiciones farmaceuticas, transdermicas sin alcohol |
| MX2010004789A (es) * | 2007-11-02 | 2010-07-05 | Acrux Dds Pty Ltd | Sistema de liberacion transdermica para hormonas y esteroides. |
| JP5073124B2 (ja) * | 2010-12-07 | 2012-11-14 | 祐徳薬品工業株式会社 | ノルアドレナリン作動性・特異的セロトニン作動性抗うつ薬含有経皮吸収型貼付製剤 |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| EP2857020A4 (en) * | 2012-06-05 | 2015-10-28 | Yutoku Pharmaceutical Ind Co Ltd | MIRTAZAPINE TRANSDERMALLY ABSORBABLE SKIN ADHESIVE PREPARATION |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10201549B2 (en) * | 2013-06-14 | 2019-02-12 | Professional Compounding Centers Of America (Pcca) | Testosterone combined with anastrozole injection solutions |
| US20150065426A1 (en) * | 2013-08-27 | 2015-03-05 | Professional Compounding Centers Of America | Testosterone Booster Transdermal Compositions |
| MX384159B (es) * | 2014-05-05 | 2025-03-14 | Repros Therapeutics Inc | Formulaciones y métodos para el suministro vaginal de antiprogestinas. |
| JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． | 天然の併用ホルモン補充療法剤及び療法 |
| PL3261645T3 (pl) * | 2015-02-27 | 2021-12-06 | Dechra Limited | Pobudzanie apetytu, zarządzanie utratą masy ciała, i leczenie anoreksji u psów i kotów |
| CN107427474A (zh) | 2015-04-13 | 2017-12-01 | 株式会社Lg生活健康 | 含有调节神经递质释放的成分的可溶性微针 |
| WO2016167545A1 (ko) * | 2015-04-13 | 2016-10-20 | 주식회사 엘지생활건강 | 신경전달물질의 배출을 조절하는 성분이 포함된 용해성 마이크로니들 |
| JP2018515552A (ja) * | 2015-05-18 | 2018-06-14 | アジル・セラピューティクス・インコーポレイテッドＡｇｉｌｅ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 避妊用組成物ならびに有効性改善および副作用調節方法 |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10449201B2 (en) * | 2015-08-17 | 2019-10-22 | Alpha To Omega Pharmaceutical Consultants, Inc. | Transdermal and/or topical delivery system comprising clobazam |
| GB201604484D0 (en) | 2016-03-16 | 2016-04-27 | Antibiotx Aps And Københavns Uni University Of Copenhagen | Topical antibacterial compositions |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| WO2018031576A1 (en) * | 2016-08-08 | 2018-02-15 | Baucom Karan Y | Hormone delivery system and method |
| CN110099688A (zh) * | 2016-11-17 | 2019-08-06 | 赛途公司 | 骨骼肌肥大诱导物 |
| KR102436756B1 (ko) * | 2017-01-31 | 2022-08-29 | 신신제약 주식회사 | 비스테로이드계 소염진통제와 살리실산 유도체를 포함하는 경피흡수 제제 |
| GB2560365B (en) | 2017-03-09 | 2021-10-20 | Brightwake Ltd | Improvements relating to apparatus negative pressure wound therapy |
| CN107929268A (zh) * | 2017-12-19 | 2018-04-20 | 郑州泰丰制药有限公司 | 一种含质子泵抑制剂药物的透皮贴剂及其制备方法 |
| WO2019140087A1 (en) * | 2018-01-10 | 2019-07-18 | Celista Pharmaceuticals Llc | Testosterone transdermal spray with film |
| US10285998B1 (en) | 2018-04-04 | 2019-05-14 | The Menopause Method, Inc. | Composition and method to aid in hormone replacement therapy |
| CN108703942B (zh) * | 2018-04-23 | 2021-04-06 | 中山大学 | 载有纳米材料包裹保胎药物的微针给药系统及制备方法 |
| EP3817731B1 (en) | 2018-07-05 | 2025-09-03 | Celista Pharmaceuticals Llc | Testosterone and estradiol transdermal spray |
| CN110947088A (zh) * | 2019-12-06 | 2020-04-03 | 广州新济薇娜生物科技有限公司 | 护眼组合贴片及其制备方法 |
| KR102592892B1 (ko) | 2021-03-12 | 2023-10-23 | 충남대학교산학협력단 | 데속시코르티코스테론 글루코사이드를 포함하는 당뇨병 예방 또는 치료용 조성물 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK534178A (da) | 1977-12-16 | 1979-06-17 | Interx Research Corp | Anticholinerge midler med sektrtionshaemmende virkning |
| US5196410A (en) * | 1986-10-31 | 1993-03-23 | Pfizer Inc. | Transdermal flux enhancing compositions |
| US4906475A (en) * | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
| JPH01308225A (ja) * | 1988-06-03 | 1989-12-12 | Nissan Chem Ind Ltd | 外用医薬組成物 |
| DE69007886T2 (de) * | 1989-07-21 | 1994-11-17 | Izhak Blank | Östradiol enthaltende Mittel und Verfahren zur topischen Anwendung. |
| US5276079A (en) * | 1991-11-15 | 1994-01-04 | Minnesota Mining And Manufacturing Company | Pressure-sensitive poly(n-vinyl lactam) adhesive composition and method for producing and using same |
| EP0661989B1 (en) * | 1992-09-21 | 1997-08-06 | PHARMACIA & UPJOHN COMPANY | Sustained-release protein formulations |
| AU5294393A (en) * | 1992-10-06 | 1994-04-26 | Upjohn Company, The | Topical pharmaceutical compositions |
| US6998138B2 (en) * | 1996-02-19 | 2006-02-14 | Acrux Dds Pty. Ltd. | Topical delivery of anti-alopecia agents |
| US7094422B2 (en) * | 1996-02-19 | 2006-08-22 | Acrux Dds Pty Ltd. | Topical delivery of antifungal agents |
| US6923983B2 (en) * | 1996-02-19 | 2005-08-02 | Acrux Dds Pty Ltd | Transdermal delivery of hormones |
| US6916487B2 (en) * | 1996-02-19 | 2005-07-12 | Acrux Dds Pty Ltd | Transdermal delivery of antiemetics |
| US6929801B2 (en) * | 1996-02-19 | 2005-08-16 | Acrux Dds Pty Ltd | Transdermal delivery of antiparkinson agents |
| AUPN814496A0 (en) * | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
| US6916486B2 (en) * | 1996-02-19 | 2005-07-12 | Acrux Dds Pty Ltd | Transdermal delivery of analgesics |
| GB9902227D0 (en) * | 1999-02-01 | 1999-03-24 | Cipla Limited | Pharmaceutical composition for topical administration |
| ATE252380T1 (de) * | 1999-02-05 | 2003-11-15 | Cipla Ltd | Topische sprays enthaltend eine filmbildende zusammensetzung |
| WO2001038329A1 (en) * | 1999-11-24 | 2001-05-31 | Sumika Fine Chemicals Co., Ltd. | Anhydrous mirtazapine crystals and process for producing the same |
| HUP0204050A3 (en) * | 2000-01-19 | 2004-09-28 | Akzo Nobel Nv | Drug combination for the treatment of depression and related disorders comprising mirtazapine and gepirone |
| WO2003039597A1 (en) * | 2001-11-09 | 2003-05-15 | Qlt Inc. | Compositions comprising a photosensitizer and a skin-penetration enhancer and their use in photodynamic treatment |
| US20050186141A1 (en) * | 2002-06-25 | 2005-08-25 | Acrux Dds Pty Ltd. | Transdermal aerosol compositions |
| JP5160018B2 (ja) * | 2002-06-25 | 2013-03-13 | アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド | 非晶質医薬組成物を用いる経皮送達速度調節 |
| AUPS317102A0 (en) * | 2002-06-25 | 2002-07-18 | Drug Delivery Solutions Pty Ltd | Transdermal aerosol compositions |
| US20050181032A1 (en) * | 2002-06-25 | 2005-08-18 | Acrux Dds Pty Ltd. | Metastable pharmaceutical compositions |
| US7704518B2 (en) * | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US20060018937A1 (en) * | 2002-10-25 | 2006-01-26 | Foamix Ltd. | Steroid kit and foamable composition and uses thereof |
| CA2433101A1 (en) * | 2003-06-23 | 2004-12-23 | Igor Gonda | Method of treatment of a female suffering from androgen insufficiency |
| US20080027033A1 (en) * | 2003-11-19 | 2008-01-31 | Acrux Dds Pty Ltd | Method and Composition for Treatment of Cutaneous Lesions |
| CN1882340A (zh) * | 2003-11-19 | 2006-12-20 | 艾克若克斯Dds有限公司 | 用于治疗或预防淀粉样变性病的方法和组合物 |
| CN102127057A (zh) | 2004-03-15 | 2011-07-20 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
| JP4613622B2 (ja) * | 2005-01-20 | 2011-01-19 | 住友電気工業株式会社 | 軟磁性材料および圧粉磁心 |
| US20070088012A1 (en) * | 2005-04-08 | 2007-04-19 | Woun Seo | Method of treating or preventing type-2 diabetes |
| CA2604431A1 (en) * | 2005-04-13 | 2006-10-26 | Unimed Pharmaceuticals, Inc. | Method of increasing testosterone and related steroid concentrations in women |
| WO2006124681A2 (en) * | 2005-05-18 | 2006-11-23 | The Gi Company, Inc. | Oral drug delivery system and methods of use thereof |
| CA2610708C (en) * | 2005-06-03 | 2013-10-08 | Acrux Dds Pty Ltd | Method and composition for transdermal drug delivery |
| US8435944B2 (en) * | 2005-06-03 | 2013-05-07 | Acrux Dds Pty Ltd. | Method and composition for transdermal drug delivery |
| CA2617934A1 (en) * | 2005-08-05 | 2007-02-15 | Nuvo Research Inc. | Transdermal drug delivery formulation |
| CA2624788C (en) * | 2005-10-12 | 2011-04-19 | Unimed Pharmaceuticals, Llc | Improved testosterone gel and method of use |
| WO2008073684A1 (en) * | 2006-12-08 | 2008-06-19 | Lipo Chemicals Inc. | Composition for treating aging skin comprising a hydroxycinnamic acid such as p-coumaric acid |
| MX2010004789A (es) * | 2007-11-02 | 2010-07-05 | Acrux Dds Pty Ltd | Sistema de liberacion transdermica para hormonas y esteroides. |
| JP5675175B2 (ja) * | 2009-06-23 | 2015-02-25 | 大陽日酸株式会社 | オゾン供給装置 |
-
2008
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- 2008-10-31 PT PT88455472T patent/PT2214643E/pt unknown
- 2008-10-31 NZ NZ585034A patent/NZ585034A/en not_active IP Right Cessation
- 2008-10-31 MX MX2010004788A patent/MX2010004788A/es active IP Right Grant
- 2008-10-31 WO PCT/AU2008/001613 patent/WO2009055859A1/en not_active Ceased
- 2008-10-31 CN CN2008801187639A patent/CN101883556B/zh not_active Expired - Fee Related
- 2008-10-31 CN CN2008801187624A patent/CN101888830B/zh not_active Expired - Fee Related
- 2008-10-31 CA CA2704116A patent/CA2704116A1/en not_active Abandoned
- 2008-10-31 US US12/740,663 patent/US20100297032A1/en not_active Abandoned
- 2008-10-31 PT PT88456009T patent/PT2219603E/pt unknown
- 2008-10-31 PL PL08845547T patent/PL2214643T3/pl unknown
- 2008-10-31 AU AU2008318283A patent/AU2008318283B2/en not_active Ceased
- 2008-10-31 AU AU2008318284A patent/AU2008318284B2/en not_active Ceased
- 2008-10-31 JP JP2010532377A patent/JP5737942B2/ja not_active Expired - Fee Related
- 2008-10-31 ES ES08845600.9T patent/ES2494853T3/es active Active
- 2008-10-31 CA CA2704117A patent/CA2704117C/en not_active Expired - Fee Related
- 2008-10-31 KR KR1020107012099A patent/KR20100094495A/ko not_active Ceased
- 2008-10-31 WO PCT/AU2008/001614 patent/WO2009055860A1/en not_active Ceased
- 2008-10-31 JP JP2010532376A patent/JP2011502172A/ja not_active Ceased
- 2008-10-31 BR BRPI0819235A patent/BRPI0819235A2/pt not_active IP Right Cessation
- 2008-10-31 DK DK08845600.9T patent/DK2219603T3/da active
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- 2008-10-31 EP EP08845600.9A patent/EP2219603B1/en not_active Not-in-force
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- 2008-10-31 KR KR1020107012100A patent/KR101662186B1/ko not_active Expired - Fee Related
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- 2008-10-31 DK DK08845547.2T patent/DK2214643T3/da active
- 2008-10-31 US US12/740,666 patent/US20100279988A1/en not_active Abandoned
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