JP2011502164A5 - - Google Patents

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Publication number
JP2011502164A5
JP2011502164A5 JP2010532233A JP2010532233A JP2011502164A5 JP 2011502164 A5 JP2011502164 A5 JP 2011502164A5 JP 2010532233 A JP2010532233 A JP 2010532233A JP 2010532233 A JP2010532233 A JP 2010532233A JP 2011502164 A5 JP2011502164 A5 JP 2011502164A5
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JP
Japan
Prior art keywords
pharmaceutical composition
peptide chain
antibody
per
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010532233A
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English (en)
Japanese (ja)
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JP2011502164A (ja
Filing date
Publication date
Priority claimed from US11/931,201 external-priority patent/US20090136505A1/en
Application filed filed Critical
Publication of JP2011502164A publication Critical patent/JP2011502164A/ja
Publication of JP2011502164A5 publication Critical patent/JP2011502164A5/ja
Pending legal-status Critical Current

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JP2010532233A 2007-10-31 2008-10-30 活性剤の中枢神経系への鼻内投与 Pending JP2011502164A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/931,201 US20090136505A1 (en) 2005-02-23 2007-10-31 Intranasal Administration of Active Agents to the Central Nervous System
PCT/US2008/081722 WO2009058957A2 (en) 2007-10-31 2008-10-30 Intranasal administration of active agents to the central nervous system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014126401A Division JP2014205698A (ja) 2007-10-31 2014-06-19 活性剤の中枢神経系への鼻内投与

Publications (2)

Publication Number Publication Date
JP2011502164A JP2011502164A (ja) 2011-01-20
JP2011502164A5 true JP2011502164A5 (https=) 2011-10-06

Family

ID=40591743

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010532233A Pending JP2011502164A (ja) 2007-10-31 2008-10-30 活性剤の中枢神経系への鼻内投与
JP2014126401A Pending JP2014205698A (ja) 2007-10-31 2014-06-19 活性剤の中枢神経系への鼻内投与

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014126401A Pending JP2014205698A (ja) 2007-10-31 2014-06-19 活性剤の中枢神経系への鼻内投与

Country Status (4)

Country Link
US (3) US20090136505A1 (https=)
EP (2) EP2207802A4 (https=)
JP (2) JP2011502164A (https=)
WO (1) WO2009058957A2 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910101B2 (en) * 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
KR100785656B1 (ko) * 2007-05-14 2007-12-17 재단법인서울대학교산학협력재단 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체
EP2769711A1 (en) 2008-07-10 2014-08-27 ESBATech, an Alcon Biomedical Research Unit LLC Methods and Compositions for Enhanced Delivery of Macromolecules
CN102933198B (zh) * 2009-09-25 2015-10-07 雷迪博士实验室有限公司 包含曲普坦化合物的制剂
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
DK2480197T3 (en) 2009-09-25 2016-01-25 Reddys Lab Ltd Dr Compositions containing triptanforbindelser
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
EP2646468B1 (en) 2010-12-01 2018-07-25 AlderBio Holdings LLC Anti-ngf compositions and use thereof
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
US8609088B2 (en) 2011-05-10 2013-12-17 Regents Of The University Of Minnesota Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
US10016473B2 (en) 2012-08-17 2018-07-10 Howard University Method, apparatus, and kit for the pulsing treatment of neurodegenerative diseases and impairments
US9101652B2 (en) 2012-08-17 2015-08-11 Howard University Method, apparatus and kit for the treatment of neurodegenerative diseases and impairments
SI2961426T1 (sl) 2013-02-26 2020-01-31 Baxalta GmbH Zdravljanje motenj centralnega živčnega sistema z intranazalnim dajanjem imunoglobulina G
HUE044737T2 (hu) 2013-05-06 2019-11-28 Baxalta Inc Alzheimer-kór szubpopulációk kezelése egyesített immunglubulin G-vel
CN115120746A (zh) 2013-05-15 2022-09-30 明尼苏达大学董事会 腺相关病毒介导的基因向中枢神经系统转移
WO2017136376A1 (en) * 2016-02-01 2017-08-10 The University Of North Carolina At Chapel Hill Polyelectrolyte complexes for delivery of agents to the cns
SG10201912761UA (en) 2016-04-15 2020-02-27 The Trustees Of The Univ Of Pennsyvania Gene therapy for treating mucopolysaccharidosis type ii
KR102883778B1 (ko) 2017-09-22 2025-11-12 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 Ii형 점액다당류증의 치료를 위한 유전자 요법
BR112020013749A2 (pt) * 2018-01-05 2020-12-01 Impel Neuropharma, Inc. dispensação intranasal de pó de levodopa por dispositivo olfativo de precisão

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476116A (en) * 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
KR850004274A (ko) * 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
FR2598081B1 (fr) * 1986-04-30 1990-02-02 Chauvin Blache Lab Procede de preparation d'une solution pharmaceutique aqueuse d'un principe actif constitue par un acide organique
GB8823869D0 (en) * 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5175384A (en) * 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
US5856298A (en) * 1989-10-13 1999-01-05 Amgen Inc. Erythropoietin isoforms
CA2070823C (en) 1989-12-05 1999-01-12 William H. Ii Frey Neurologic agents for nasal administration to the brain
ATE158021T1 (de) * 1990-08-29 1997-09-15 Genpharm Int Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
US5545806A (en) * 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
GB9020544D0 (en) * 1990-09-20 1990-10-31 Sandoz Ltd Improvements in or relating to organic compounds
US5661130A (en) 1993-06-24 1997-08-26 The Uab Research Foundation Absorption enhancers for drug administration
US5830853A (en) * 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
WO1995011042A1 (en) 1993-10-21 1995-04-27 Hisamitsu Pharmaceutical Co., Inc. Pernasal composition and pernasal preparation containing the same
JP3597233B2 (ja) * 1993-10-21 2004-12-02 久光製薬株式会社 経鼻組成物及びそれを含有する経鼻製剤
US5897858A (en) * 1994-02-03 1999-04-27 Schering-Plough Healthcare Products, Inc. Nasal spray compositions exhibiting increased retention in the nasal cavity
BR9606838A (pt) 1995-01-23 1999-11-30 Direct Haler A S Inalador
DE19544393A1 (de) 1995-11-15 1997-05-22 Hoechst Schering Agrevo Gmbh Synergistische herbizide Mischungen
GB9700624D0 (en) * 1997-01-14 1997-03-05 Danbiosyst Uk Drug delivery composition
IT1289608B1 (it) 1997-02-05 1998-10-15 Angelini Ricerche Spa Composizione per uso terapeutico o diagnostico somministrabile per via intranasale,sublinguale o vaginale
US6235883B1 (en) * 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
US6750324B1 (en) * 1997-12-02 2004-06-15 Neuralab Limited Humanized and chimeric N-terminal amyloid beta-antibodies
US6761888B1 (en) * 2000-05-26 2004-07-13 Neuralab Limited Passive immunization treatment of Alzheimer's disease
US6703381B1 (en) 1998-08-14 2004-03-09 Nobex Corporation Methods for delivery therapeutic compounds across the blood-brain barrier
ES2252993T3 (es) 1998-12-09 2006-05-16 Chiron Corporation Administracion de agentes neurotroficos al sistema nervioso central.
US7273618B2 (en) * 1998-12-09 2007-09-25 Chiron Corporation Method for administering agents to the central nervous system
EP1135105B1 (en) 1998-12-09 2005-03-02 Chiron Corporation Use of a neurologic agent for the manufacture of a medicament for the treatment of a central nervous system disorder
CN1736502A (zh) * 1999-03-03 2006-02-22 奥普蒂诺斯公司 鼻传送装置
MXPA02001417A (es) 1999-08-09 2002-08-12 Lexigen Pharm Corp Complejos multiples de citosina-anticuerpo.
US6824780B1 (en) * 1999-10-29 2004-11-30 Genentech, Inc. Anti-tumor antibody compositions and methods of use
GB0007850D0 (en) 2000-03-31 2000-05-17 Microbiological Res Authority Passive and active protection against mycobacterial infections
WO2001082902A1 (en) * 2000-04-28 2001-11-08 Zengen, Inc. Method and composition for rapid delivery of bioactive compounds to the systemic circulation via the nasal membrane
KR20030074693A (ko) * 2000-12-28 2003-09-19 알투스 바이올로직스 인코포레이티드 전항체 및 이의 단편의 결정과 이의 제조 및 사용 방법
AU2002303159A1 (en) * 2001-03-26 2002-10-08 Linden Technologies, Inc. Polymer synthesis
US20040028613A1 (en) * 2001-06-25 2004-02-12 Nastech Pharmaceutical Company Inc Dopamine agonist formulations for enhanced central nervous system delivery
US20070004743A1 (en) 2002-02-25 2007-01-04 Xiao Linda L Intranasal administration of mc4-r agonists
US20040115153A1 (en) * 2002-12-17 2004-06-17 L'oreal Compositions containing at least one oil structured with at least one silicone-polyamide polymer, and at least one silicone gum and methods of using the same
US7241733B2 (en) 2002-06-28 2007-07-10 Centocor, Inc. Mammalian EPO mimetic CH1 deleted mimetibodies, compositions, methods and uses
US7166575B2 (en) * 2002-12-17 2007-01-23 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity
US6734427B1 (en) * 2003-02-14 2004-05-11 United Microelectronics Corp. TEM/SEM sample preparation
GB0315632D0 (en) * 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations
US20060188496A1 (en) * 2005-02-23 2006-08-24 Hanne Bentz Intranasal administration of active agents to the central nervous system
WO2007016562A2 (en) * 2005-07-29 2007-02-08 Amgen Inc. Formulations that inhibit protein aggregation
WO2008023050A1 (en) * 2006-08-25 2008-02-28 Novo Nordisk A/S Acylated exendin-4 compounds
CA2667466A1 (en) * 2006-10-27 2008-05-02 Ablynx N.V. Intranasal delivery of polypeptides and proteins

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