JP2018033454A5 - - Google Patents
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- Publication number
- JP2018033454A5 JP2018033454A5 JP2017161826A JP2017161826A JP2018033454A5 JP 2018033454 A5 JP2018033454 A5 JP 2018033454A5 JP 2017161826 A JP2017161826 A JP 2017161826A JP 2017161826 A JP2017161826 A JP 2017161826A JP 2018033454 A5 JP2018033454 A5 JP 2018033454A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- humanized anti
- amino acid
- acid sequence
- htfr antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021200504A JP7232889B2 (ja) | 2016-08-25 | 2021-12-10 | 抗体融合蛋白質の製造方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016164901 | 2016-08-25 | ||
| JP2016164901 | 2016-08-25 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021200504A Division JP7232889B2 (ja) | 2016-08-25 | 2021-12-10 | 抗体融合蛋白質の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018033454A JP2018033454A (ja) | 2018-03-08 |
| JP2018033454A5 true JP2018033454A5 (https=) | 2020-06-25 |
| JP6993814B2 JP6993814B2 (ja) | 2022-01-14 |
Family
ID=61246169
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017161826A Active JP6993814B2 (ja) | 2016-08-25 | 2017-08-25 | 抗体融合蛋白質の製造方法 |
| JP2021200504A Active JP7232889B2 (ja) | 2016-08-25 | 2021-12-10 | 抗体融合蛋白質の製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021200504A Active JP7232889B2 (ja) | 2016-08-25 | 2021-12-10 | 抗体融合蛋白質の製造方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11512135B2 (https=) |
| EP (1) | EP3505538B1 (https=) |
| JP (2) | JP6993814B2 (https=) |
| KR (1) | KR102318480B1 (https=) |
| CN (1) | CN109641971B (https=) |
| AU (1) | AU2017316955B2 (https=) |
| BR (1) | BR112019003622A2 (https=) |
| CA (1) | CA3034589A1 (https=) |
| MX (1) | MX389073B (https=) |
| SG (1) | SG11201901495YA (https=) |
| WO (1) | WO2018038243A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA039366B1 (ru) | 2015-06-24 | 2022-01-19 | Джей Си Ар ФАРМАСЬЮТИКАЛЗ КО., ЛТД. | Антитело к рецептору трансферрина человека, проникающее через гематоэнцефалический барьер |
| AU2016283344B2 (en) | 2015-06-24 | 2022-08-04 | Jcr Pharmaceuticals Co., Ltd. | Fusion protein containing BDNF |
| KR102497564B1 (ko) | 2016-12-26 | 2023-02-07 | 제이씨알 파마 가부시키가이샤 | 혈액뇌관문을 통과하는 신규한 항인간 트랜스페린 수용체 항체 |
| CA3052936A1 (en) | 2016-12-26 | 2018-07-05 | Jcr Pharmaceuticals Co., Ltd. | Fusion protein of bdnf and anti-transferrin receptor antibody |
| CN111278453A (zh) * | 2017-09-07 | 2020-06-12 | Jcr制药股份有限公司 | 水性药物组合物 |
| CR20200129A (es) | 2017-10-02 | 2020-08-22 | Denali Therapeutics Inc | Proteínas de fusión que comprenden enzimas de terapia de reemplazo de enzimas |
| IL276327B2 (en) * | 2018-02-05 | 2024-05-01 | Japan Chem Res | Method for delivering drug to muscle |
| EP3560945A1 (en) * | 2018-04-27 | 2019-10-30 | F. Hoffmann-La Roche AG | Methods for purification of polypeptides using polysorbates |
| JP6951051B2 (ja) * | 2018-05-24 | 2021-10-20 | ＨＯＹＡ Ｔｅｃｈｎｏｓｕｒｇｉｃａｌ株式会社 | 吸着剤の生産方法 |
| KR102692543B1 (ko) * | 2018-10-26 | 2024-08-07 | 재단법인 목암생명과학연구소 | Ids를 포함하는 융합 단백질 및 이의 용도 |
| EP4229192A1 (en) | 2020-10-14 | 2023-08-23 | Denali Therapeutics Inc. | Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof |
| TW202342542A (zh) * | 2020-12-23 | 2023-11-01 | 大陸商廣東菲鵬製藥股份有限公司 | 抗pd-l1抗體、編碼其的核酸、包含其的載體、細胞、藥物組合物及其用途 |
| EP4291246A4 (en) * | 2021-02-11 | 2024-12-11 | Denali Therapeutics Inc. | ANTI-TRANSFERRIN RECEPTOR FUSION PROTEINS AND METHODS OF USE THEREOF |
| EP4299756A4 (en) | 2021-03-09 | 2025-03-12 | JCR Pharmaceuticals Co., Ltd. | METHOD FOR PRODUCING AN ANTIBODY LYSOSOMALIC ENZYMFUSION PROTEIN |
| CA3244685A1 (en) * | 2021-12-28 | 2025-06-13 | Jcr Pharmaceuticals Co., Ltd. | Fusion protein of anti-transferrin receptor antibody and physiologically active protein for safe gene therapy |
| WO2024010067A1 (ja) * | 2022-07-08 | 2024-01-11 | Ｊｃｒファーマ株式会社 | 中枢神経系疾患の治療のための、核酸分子、ベクター、組換え細胞及び薬剤 |
| TW202542190A (zh) | 2023-12-20 | 2025-11-01 | 美商戴納立製藥公司 | 包含酸性α—葡萄糖苷酶之融合蛋白及其方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2537273A1 (en) * | 2003-09-05 | 2005-03-17 | Gtc Biotherapeutics, Inc. | Method for the production of fusion proteins in transgenic mammal milk |
| US20050100965A1 (en) | 2003-11-12 | 2005-05-12 | Tariq Ghayur | IL-18 binding proteins |
| MY157915A (en) * | 2004-12-21 | 2016-08-15 | Centocor Inc | Anti-il-12 antibodies, epitopes, compositions, methods and uses. |
| EP2089424B1 (en) | 2006-12-06 | 2015-07-01 | JCR PHARMACEUTICALS Co., LTD. | Method for production of human erythropoietin |
| MX2009006398A (es) * | 2006-12-12 | 2009-06-23 | Biorexis Pharmaceutical Corp | Genotecas de proteinas de fusion de transferrina. |
| JP2009273427A (ja) | 2008-05-16 | 2009-11-26 | Jcr Pharmaceuticals Co Ltd | 組換え体ヒトｆｓｈの製造方法 |
| US8058407B2 (en) * | 2008-10-31 | 2011-11-15 | Wyeth Llc | Purification of acidic proteins using ceramic hydroxyapatite chromatography |
| EP2485761B1 (en) | 2009-10-09 | 2019-02-27 | Armagen, Inc. | Methods and compositions for increasing iduronate 2-sulfatase activity in the cns |
| WO2012101671A1 (en) * | 2011-01-25 | 2012-08-02 | Jcr Pharmaceuticals Co., Ltd. | Method for production of human recombinant iduronate 2-sulfatase |
| JP6018572B2 (ja) * | 2011-01-25 | 2016-11-02 | Ｊｃｒファーマ株式会社 | 組換えヒトイズロン酸−２−スルファターゼの製造方法 |
| BR112014013250A2 (pt) * | 2011-12-01 | 2019-09-24 | Angiochem Inc | compostos com enzima alvo e usos dos mesmos |
| KR101380740B1 (ko) | 2012-06-29 | 2014-04-11 | 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 | 이듀로네이트-2-설파타제의 정제 |
| WO2014016873A1 (en) * | 2012-07-26 | 2014-01-30 | Jcr Pharmaceuticals Co., Ltd. | Method for production of recombinant human alpha-galactosidase a |
| EP3088518A4 (en) | 2013-12-25 | 2017-09-20 | JCR Pharmaceuticals Co., Ltd. | Novel anti-transferrin receptor antibody that passes through blood-brain barrier |
| JP6071018B2 (ja) | 2014-10-31 | 2017-02-01 | Ｊｃｒファーマ株式会社 | 組換えヒトＤＮａｓｅＩの製造方法 |
| WO2016116966A1 (en) | 2015-01-22 | 2016-07-28 | Jcr Pharmaceuticals Co., Ltd. | Method for purification of recombinant human alpha-galactosidase a from material containing contaminant host cell proteins |
-
2017
- 2017-08-25 SG SG11201901495YA patent/SG11201901495YA/en unknown
- 2017-08-25 JP JP2017161826A patent/JP6993814B2/ja active Active
- 2017-08-25 WO PCT/JP2017/030470 patent/WO2018038243A1/ja not_active Ceased
- 2017-08-25 CA CA3034589A patent/CA3034589A1/en active Pending
- 2017-08-25 BR BR112019003622-9A patent/BR112019003622A2/pt unknown
- 2017-08-25 CN CN201780051299.5A patent/CN109641971B/zh active Active
- 2017-08-25 US US16/327,982 patent/US11512135B2/en active Active
- 2017-08-25 MX MX2019002252A patent/MX389073B/es unknown
- 2017-08-25 EP EP17843719.0A patent/EP3505538B1/en active Active
- 2017-08-25 AU AU2017316955A patent/AU2017316955B2/en active Active
- 2017-08-25 KR KR1020197007992A patent/KR102318480B1/ko active Active
-
2021
- 2021-12-10 JP JP2021200504A patent/JP7232889B2/ja active Active