JP2011190277A5 - - Google Patents
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- Publication number
- JP2011190277A5 JP2011190277A5 JP2011137461A JP2011137461A JP2011190277A5 JP 2011190277 A5 JP2011190277 A5 JP 2011190277A5 JP 2011137461 A JP2011137461 A JP 2011137461A JP 2011137461 A JP2011137461 A JP 2011137461A JP 2011190277 A5 JP2011190277 A5 JP 2011190277A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- oso
- hydrogen
- cyano
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 125000004093 cyano group Chemical group *C#N 0.000 claims 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 3
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical group C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 claims 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000004063 butyryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
- 125000003774 valeryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03293152A EP1544195A1 (en) | 2003-12-15 | 2003-12-15 | 1-N-phenyl-amino- 1H-imidazole derivatives and pharmaceutical compositions containing them |
| EP03293152.9 | 2003-12-15 | ||
| EP04292681 | 2004-11-12 | ||
| EP04292681.6 | 2004-11-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006544394A Division JP4834557B2 (ja) | 2003-12-15 | 2004-12-15 | １−ｎ−フェニルアミノ−１ｈ−イミダゾール誘導体及びこれを含む医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011190277A JP2011190277A (ja) | 2011-09-29 |
| JP2011190277A5 true JP2011190277A5 (enExample) | 2012-07-19 |
| JP5209760B2 JP5209760B2 (ja) | 2013-06-12 |
Family
ID=34702365
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006544394A Expired - Fee Related JP4834557B2 (ja) | 2003-12-15 | 2004-12-15 | １−ｎ−フェニルアミノ−１ｈ−イミダゾール誘導体及びこれを含む医薬組成物 |
| JP2011137461A Expired - Fee Related JP5209760B2 (ja) | 2003-12-15 | 2011-06-21 | １−ｎ−フェニルアミノ−１ｈ−イミダゾール誘導体及びこれを含む医薬組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006544394A Expired - Fee Related JP4834557B2 (ja) | 2003-12-15 | 2004-12-15 | １−ｎ−フェニルアミノ−１ｈ−イミダゾール誘導体及びこれを含む医薬組成物 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8476455B2 (enExample) |
| EP (1) | EP1694650A1 (enExample) |
| JP (2) | JP4834557B2 (enExample) |
| KR (1) | KR20060123186A (enExample) |
| CN (1) | CN1890221B (enExample) |
| AR (1) | AR047144A1 (enExample) |
| AU (1) | AU2004299286B2 (enExample) |
| BR (1) | BRPI0417407A (enExample) |
| CA (1) | CA2549603A1 (enExample) |
| IL (1) | IL176077A0 (enExample) |
| MA (1) | MA28286A1 (enExample) |
| MX (1) | MXPA06006837A (enExample) |
| NO (1) | NO20062710L (enExample) |
| NZ (1) | NZ548399A (enExample) |
| OA (1) | OA13336A (enExample) |
| RU (1) | RU2365586C2 (enExample) |
| TW (1) | TW200533668A (enExample) |
| WO (1) | WO2005058842A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0127923D0 (en) | 2001-11-21 | 2002-01-16 | Sterix Ltd | Compound |
| CA2656627A1 (en) * | 2006-07-05 | 2008-01-10 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Sulfamatobenzothiophene derivatives |
| AU2007327943A1 (en) * | 2006-12-04 | 2008-06-12 | Merck Patent Gmbh | Sulphamate benzothiophene derivatives |
| CA2698814A1 (en) | 2007-09-17 | 2009-03-26 | Preglem S.A. | Treatment of oestrogen dependant conditions in pre-menopausal women |
| GB0914767D0 (en) * | 2009-08-24 | 2009-09-30 | Sterix Ltd | Compound |
| HRP20221462T1 (hr) | 2015-12-09 | 2023-01-20 | The Board Of Trustees Of The University Of Illinois | Selektivni nishodni regulatori receptora estrogena na bazi benzotiofena |
| EP3565558B1 (en) | 2017-01-06 | 2023-12-06 | G1 Therapeutics, Inc. | Combination therapy with a serd compound and a cdk4/6 inhibitor for the treatment of cancer |
| WO2018187414A1 (en) * | 2017-04-05 | 2018-10-11 | The Regents Of The University Of California | Inhibitors of mtor-rictor interactions |
| EP3801221A4 (en) * | 2018-06-11 | 2022-03-30 | Loma Linda University | Methods of delaying and reversing alzheimer's disease progression |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3558625A (en) * | 1968-10-31 | 1971-01-26 | Merck & Co Inc | Pyrazinecarboxyaldehydes and method for their preparation |
| BE757186A (fr) | 1969-10-07 | 1971-04-07 | Bayer Ag | Nouveaux esters d'acides pyridazino-thiono-phosphoriques et-phosphoniques, leur procede de preparation et leur application comme insecticides et acaricides |
| US4166452A (en) * | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) * | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) * | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US4584302A (en) | 1983-09-26 | 1986-04-22 | Mcneilab, Inc. | Methods for the treatment of ventricular dysrhythmia and prevention of ventricular fibrillation |
| US4749713A (en) * | 1986-03-07 | 1988-06-07 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| US4937250A (en) * | 1988-03-07 | 1990-06-26 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| US5071861A (en) | 1986-03-07 | 1991-12-10 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
| DE3811574A1 (de) * | 1988-03-31 | 1989-10-19 | Schering Ag | N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| JP2500849B2 (ja) * | 1991-09-02 | 1996-05-29 | 山之内製薬株式会社 | トリアゾリル置換３級アミノ化合物又はその塩 |
| HU220863B1 (en) * | 1991-09-02 | 2002-06-29 | Yamanouchi Pharma Co Ltd | Triazolylated tertiary amines, process for producing them and pharmaceutical compositions containing them |
| GB2273704B (en) * | 1992-12-16 | 1997-01-22 | Orion Yhtymae Oy | Triazolyl diaryl selective aromatase inhibiting compounds |
| WO1996035688A1 (en) | 1995-05-08 | 1996-11-14 | Nippon Chemiphar Co., Ltd. | 2,4-thiazolidinedione or oxazolidinedione derivatives and hypoglycemic agent |
| DE19731328A1 (de) * | 1997-07-22 | 1999-01-28 | Hoechst Ag | Imidazol-Derivate mit Biphenylsulfonylcyanamid-Seitenkette, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| GB9807779D0 (en) | 1998-04-09 | 1998-06-10 | Ciba Geigy Ag | Organic compounds |
| US6248780B1 (en) | 1998-10-01 | 2001-06-19 | Duquesne University Of The Holy Ghost | Compounds for the treatment of estrogen-dependent illnesses and methods for making and using the same |
| JP4320089B2 (ja) * | 1999-07-06 | 2009-08-26 | あすか製薬株式会社 | フェニルスルファメート誘導体 |
| US6436972B1 (en) | 2000-04-10 | 2002-08-20 | Dalhousie University | Pyridones and their use as modulators of serine hydrolase enzymes |
| JP2004524289A (ja) | 2000-12-22 | 2004-08-12 | アストラゼネカ・アクチエボラーグ | 治療化合物 |
| TR200301890T2 (tr) | 2001-02-23 | 2004-12-21 | K. U. Leuven Research & Development | HIV-İnhibe edici N-Aminoimidazol türevleri. |
| CN1370533A (zh) | 2001-02-27 | 2002-09-25 | 中国人民解放军军事医学科学院放射医学研究所 | 一类新的苯并噻吩类化合物在防治妇女绝经后综合症和其它与雌激素相关疾病中的用途 |
| US7109193B2 (en) * | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
| GB0127923D0 (en) * | 2001-11-21 | 2002-01-16 | Sterix Ltd | Compound |
| BR0214373A (pt) * | 2001-11-21 | 2004-10-13 | Sterix Ltd | Derivados de 1,2,4-triazol contendo um grupo sulfamato como inibidores de aromatase |
| US6737433B1 (en) | 2002-12-16 | 2004-05-18 | Laboratoire Theramex | 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors and pharmaceutical compositions containing them |
| JP2004196795A (ja) * | 2002-12-16 | 2004-07-15 | Wyeth | 外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル |
| EP1644350B1 (en) | 2003-05-16 | 2009-07-01 | Laboratoire Theramex | Sulfamate benzothiophene derivatives as steroid sulfatase inhibitors |
-
2004
- 2004-12-15 TW TW093138979A patent/TW200533668A/zh unknown
- 2004-12-15 WO PCT/EP2004/014847 patent/WO2005058842A1/en not_active Ceased
- 2004-12-15 JP JP2006544394A patent/JP4834557B2/ja not_active Expired - Fee Related
- 2004-12-15 BR BRPI0417407-0A patent/BRPI0417407A/pt not_active IP Right Cessation
- 2004-12-15 EP EP04804432A patent/EP1694650A1/en not_active Withdrawn
- 2004-12-15 OA OA1200600193A patent/OA13336A/en unknown
- 2004-12-15 NZ NZ548399A patent/NZ548399A/en unknown
- 2004-12-15 CA CA002549603A patent/CA2549603A1/en not_active Abandoned
- 2004-12-15 US US10/582,778 patent/US8476455B2/en not_active Expired - Fee Related
- 2004-12-15 MX MXPA06006837A patent/MXPA06006837A/es active IP Right Grant
- 2004-12-15 AU AU2004299286A patent/AU2004299286B2/en not_active Ceased
- 2004-12-15 CN CN200480036357.XA patent/CN1890221B/zh not_active Expired - Fee Related
- 2004-12-15 KR KR1020067010009A patent/KR20060123186A/ko not_active Ceased
- 2004-12-15 RU RU2006125417/04A patent/RU2365586C2/ru not_active IP Right Cessation
- 2004-12-15 AR ARP040104657A patent/AR047144A1/es not_active Application Discontinuation
-
2006
- 2006-05-31 IL IL176077A patent/IL176077A0/en unknown
- 2006-06-12 NO NO20062710A patent/NO20062710L/no not_active Application Discontinuation
- 2006-07-07 MA MA29173A patent/MA28286A1/fr unknown
-
2011
- 2011-06-21 JP JP2011137461A patent/JP5209760B2/ja not_active Expired - Fee Related
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