JP2011117973A5 - - Google Patents
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- Publication number
- JP2011117973A5 JP2011117973A5 JP2011032661A JP2011032661A JP2011117973A5 JP 2011117973 A5 JP2011117973 A5 JP 2011117973A5 JP 2011032661 A JP2011032661 A JP 2011032661A JP 2011032661 A JP2011032661 A JP 2011032661A JP 2011117973 A5 JP2011117973 A5 JP 2011117973A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- plate
- well
- ptx3
- buffer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 11
- 239000000243 solution Substances 0.000 claims 11
- 239000011534 wash buffer Substances 0.000 claims 6
- 108700025763 PTX3 Proteins 0.000 claims 5
- 239000007853 buffer solution Substances 0.000 claims 5
- 238000005406 washing Methods 0.000 claims 5
- 239000013060 biological fluid Substances 0.000 claims 4
- 230000000903 blocking effect Effects 0.000 claims 3
- 230000009871 nonspecific binding Effects 0.000 claims 3
- YRNWIFYIFSBPAU-UHFFFAOYSA-N 4-[4-(dimethylamino)phenyl]-n,n-dimethylaniline Chemical compound C1=CC(N(C)C)=CC=C1C1=CC=C(N(C)C)C=C1 YRNWIFYIFSBPAU-UHFFFAOYSA-N 0.000 claims 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 2
- 101100352284 Homo sapiens PITX3 gene Proteins 0.000 claims 2
- 101100031710 Homo sapiens PTX3 gene Proteins 0.000 claims 2
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 2
- 229920001213 Polysorbate 20 Polymers 0.000 claims 2
- 108010090804 Streptavidin Proteins 0.000 claims 2
- 229940098773 bovine serum albumin Drugs 0.000 claims 2
- 239000003593 chromogenic compound Substances 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims 2
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims 2
- 239000012089 stop solution Substances 0.000 claims 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 238000002965 ELISA Methods 0.000 claims 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 claims 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 239000012895 dilution Substances 0.000 claims 1
- 210000004408 hybridoma Anatomy 0.000 claims 1
- 238000011534 incubation Methods 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 102000013415 peroxidase activity proteins Human genes 0.000 claims 1
- 108040007629 peroxidase activity proteins Proteins 0.000 claims 1
- 239000008363 phosphate buffer Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000858A ITMI20040858A1 (it) | 2004-04-29 | 2004-04-29 | Anticorpi monoclonali ibridomi metodo migliorato per determinare la proteina ptx3 e kit per detta determinazione |
| ITMI2004A000858 | 2004-04-29 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007509981A Division JP2007534951A (ja) | 2004-04-29 | 2005-04-27 | タンパク質ｐｔｘ３測定用の単クローン抗体、ハイブリドーマ、改良方法、及び前記測定用キット |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011117973A JP2011117973A (ja) | 2011-06-16 |
| JP2011117973A5 true JP2011117973A5 (enExample) | 2012-01-12 |
Family
ID=35242298
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007509981A Pending JP2007534951A (ja) | 2004-04-29 | 2005-04-27 | タンパク質ｐｔｘ３測定用の単クローン抗体、ハイブリドーマ、改良方法、及び前記測定用キット |
| JP2011032661A Pending JP2011117973A (ja) | 2004-04-29 | 2011-02-17 | タンパク質ｐｔｘ３測定用の単クローン抗体、ハイブリドーマ、改良方法、及び前記測定用キット |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007509981A Pending JP2007534951A (ja) | 2004-04-29 | 2005-04-27 | タンパク質ｐｔｘ３測定用の単クローン抗体、ハイブリドーマ、改良方法、及び前記測定用キット |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7915004B2 (enExample) |
| EP (1) | EP1740956A2 (enExample) |
| JP (2) | JP2007534951A (enExample) |
| KR (1) | KR101168292B1 (enExample) |
| CN (1) | CN1947018B (enExample) |
| AU (1) | AU2005238637B2 (enExample) |
| CA (1) | CA2562895A1 (enExample) |
| IT (1) | ITMI20040858A1 (enExample) |
| WO (1) | WO2005106494A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1947460B1 (en) * | 2005-11-11 | 2012-05-30 | The University of Tokyo | Method of measuring ptx3 with high sensitivity |
| JP5199120B2 (ja) * | 2005-12-29 | 2013-05-15 | ヒューマニタス・ミラソーレ・エス．ピー．エー． | 妊娠における炎症性内皮機能障害に対する診断試験 |
| ATE475098T1 (de) * | 2006-12-22 | 2010-08-15 | Humanitas Mirasole Spa | Verfahren zur messung von plasmaspiegeln von pentraxin ptx3 |
| WO2008099608A1 (ja) * | 2007-02-15 | 2008-08-21 | Saitama Medical University | 炎症性腸疾患の診断方法 |
| JP5832479B2 (ja) | 2012-08-09 | 2015-12-16 | 日本特殊陶業株式会社 | ガスセンサ |
| TWI528969B (zh) * | 2013-06-07 | 2016-04-11 | 國立成功大學 | 胺基酸序列用於製備抑制ｐｔｘ３治療鼻咽癌之醫藥組合物之用途 |
| CN106950366B (zh) * | 2017-02-15 | 2019-03-22 | 中国医学科学院北京协和医院 | 一种acpa阴性的ra诊断标志物及其应用 |
| TWI741216B (zh) * | 2017-09-19 | 2021-10-01 | 臻崴生物科技有限公司 | 專一性抑制或減緩ｐｔｘ３與ｐｔｘ３受體結合之單株抗體或其抗原結合片段及其用途 |
| TWI754171B (zh) | 2018-09-14 | 2022-02-01 | 臻崴生物科技有限公司 | 含單株抗體或其抗原結合片段之醫藥組成物及其用途 |
| CN111024956A (zh) * | 2019-12-31 | 2020-04-17 | 江苏美克医学技术有限公司 | 一种检测ptx3的时间分辨荧光免疫层析试剂盒 |
| US20230251274A1 (en) * | 2020-06-25 | 2023-08-10 | Humanitas Mirasole S.P.A. | Ptx3 as prognostic marker in covid-19 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05340945A (ja) * | 1992-06-05 | 1993-12-24 | Shiseido Co Ltd | 微量物質測定方法及び測定キット |
| JPH0875737A (ja) * | 1994-09-06 | 1996-03-22 | Fuji Yakuhin Kogyo Kk | ヒト前立腺特異抗原とヒトプロテインｃインヒビターとの複合体の測定方法および同測定用キット |
| JPH09220096A (ja) * | 1996-02-16 | 1997-08-26 | Meiji Milk Prod Co Ltd | コレラトキシン及びその中和活性の新規 高感度測定法及び同キット |
| JP4427182B2 (ja) * | 1997-09-22 | 2010-03-03 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 抗原を安定化するための緩衝液 |
| JP2002014098A (ja) * | 2000-06-28 | 2002-01-18 | Fujirebio Inc | 免疫測定方法及びそのためのキット |
| ITRM20020109A1 (it) | 2002-02-28 | 2003-08-28 | Sigma Tau Ind Farmaceuti | Derivati funzionali della pentraxina lunga ptx3 per preparare un vaccino autologo per la cura dei tumori. |
| US20040137544A1 (en) | 2002-10-31 | 2004-07-15 | Roberto Latini | PTX3 as an early prognostic indicator of cardiovascular and cerebrovascular pathologies |
| JP4667372B2 (ja) * | 2004-02-25 | 2011-04-13 | 株式会社ペルセウスプロテオミクス | 血管障害の程度の判定方法 |
-
2004
- 2004-04-29 IT IT000858A patent/ITMI20040858A1/it unknown
-
2005
- 2005-04-27 WO PCT/EP2005/004637 patent/WO2005106494A2/en not_active Ceased
- 2005-04-27 CA CA002562895A patent/CA2562895A1/en not_active Abandoned
- 2005-04-27 US US11/587,528 patent/US7915004B2/en not_active Expired - Fee Related
- 2005-04-27 KR KR1020067024272A patent/KR101168292B1/ko not_active Expired - Fee Related
- 2005-04-27 CN CN2005800134880A patent/CN1947018B/zh not_active Expired - Fee Related
- 2005-04-27 AU AU2005238637A patent/AU2005238637B2/en not_active Ceased
- 2005-04-27 JP JP2007509981A patent/JP2007534951A/ja active Pending
- 2005-04-27 EP EP05742234A patent/EP1740956A2/en not_active Withdrawn
-
2011
- 2011-02-17 JP JP2011032661A patent/JP2011117973A/ja active Pending
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