CN1947018B - 单克隆抗体、杂交瘤、测定ptx3蛋白质的改进方法以及用于上述测定的试剂盒 - Google Patents

单克隆抗体、杂交瘤、测定ptx3蛋白质的改进方法以及用于上述测定的试剂盒 Download PDF

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Publication number
CN1947018B
CN1947018B CN2005800134880A CN200580013488A CN1947018B CN 1947018 B CN1947018 B CN 1947018B CN 2005800134880 A CN2005800134880 A CN 2005800134880A CN 200580013488 A CN200580013488 A CN 200580013488A CN 1947018 B CN1947018 B CN 1947018B
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China
Prior art keywords
ptx3
solution
plate
well
monoclonal antibody
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Expired - Fee Related
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CN2005800134880A
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English (en)
Chinese (zh)
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CN1947018A (zh
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A·曼托瓦尼
G·佩里
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LECTIO PHARMAENTWICKLUNGS- und VERWERTUNGS GmbH
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Farma Development Srl
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CN2005800134880A 2004-04-29 2005-04-27 单克隆抗体、杂交瘤、测定ptx3蛋白质的改进方法以及用于上述测定的试剂盒 Expired - Fee Related CN1947018B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000858A ITMI20040858A1 (it) 2004-04-29 2004-04-29 Anticorpi monoclonali ibridomi metodo migliorato per determinare la proteina ptx3 e kit per detta determinazione
ITMI2004A000858 2004-04-29
PCT/EP2005/004637 WO2005106494A2 (en) 2004-04-29 2005-04-27 Monoclonal antibodies, hybridomas, improved method for determining the protein ptx3 and kit for said determination

Publications (2)

Publication Number Publication Date
CN1947018A CN1947018A (zh) 2007-04-11
CN1947018B true CN1947018B (zh) 2012-12-19

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ID=35242298

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CN2005800134880A Expired - Fee Related CN1947018B (zh) 2004-04-29 2005-04-27 单克隆抗体、杂交瘤、测定ptx3蛋白质的改进方法以及用于上述测定的试剂盒

Country Status (9)

Country Link
US (1) US7915004B2 (enExample)
EP (1) EP1740956A2 (enExample)
JP (2) JP2007534951A (enExample)
KR (1) KR101168292B1 (enExample)
CN (1) CN1947018B (enExample)
AU (1) AU2005238637B2 (enExample)
CA (1) CA2562895A1 (enExample)
IT (1) ITMI20040858A1 (enExample)
WO (1) WO2005106494A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1947460B1 (en) * 2005-11-11 2012-05-30 The University of Tokyo Method of measuring ptx3 with high sensitivity
JP5199120B2 (ja) * 2005-12-29 2013-05-15 ヒューマニタス・ミラソーレ・エス．ピー．エー． 妊娠における炎症性内皮機能障害に対する診断試験
ATE475098T1 (de) * 2006-12-22 2010-08-15 Humanitas Mirasole Spa Verfahren zur messung von plasmaspiegeln von pentraxin ptx3
WO2008099608A1 (ja) * 2007-02-15 2008-08-21 Saitama Medical University 炎症性腸疾患の診断方法
JP5832479B2 (ja) 2012-08-09 2015-12-16 日本特殊陶業株式会社 ガスセンサ
TWI528969B (zh) * 2013-06-07 2016-04-11 國立成功大學 胺基酸序列用於製備抑制ｐｔｘ３治療鼻咽癌之醫藥組合物之用途
CN106950366B (zh) * 2017-02-15 2019-03-22 中国医学科学院北京协和医院 一种acpa阴性的ra诊断标志物及其应用
TWI741216B (zh) * 2017-09-19 2021-10-01 臻崴生物科技有限公司 專一性抑制或減緩ｐｔｘ３與ｐｔｘ３受體結合之單株抗體或其抗原結合片段及其用途
TWI754171B (zh) 2018-09-14 2022-02-01 臻崴生物科技有限公司 含單株抗體或其抗原結合片段之醫藥組成物及其用途
CN111024956A (zh) * 2019-12-31 2020-04-17 江苏美克医学技术有限公司 一种检测ptx3的时间分辨荧光免疫层析试剂盒
US20230251274A1 (en) * 2020-06-25 2023-08-10 Humanitas Mirasole S.P.A. Ptx3 as prognostic marker in covid-19

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05340945A (ja) * 1992-06-05 1993-12-24 Shiseido Co Ltd 微量物質測定方法及び測定キット
JPH0875737A (ja) * 1994-09-06 1996-03-22 Fuji Yakuhin Kogyo Kk ヒト前立腺特異抗原とヒトプロテインｃインヒビターとの複合体の測定方法および同測定用キット
JPH09220096A (ja) * 1996-02-16 1997-08-26 Meiji Milk Prod Co Ltd コレラトキシン及びその中和活性の新規 高感度測定法及び同キット
JP4427182B2 (ja) * 1997-09-22 2010-03-03 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 抗原を安定化するための緩衝液
JP2002014098A (ja) * 2000-06-28 2002-01-18 Fujirebio Inc 免疫測定方法及びそのためのキット
ITRM20020109A1 (it) 2002-02-28 2003-08-28 Sigma Tau Ind Farmaceuti Derivati funzionali della pentraxina lunga ptx3 per preparare un vaccino autologo per la cura dei tumori.
US20040137544A1 (en) 2002-10-31 2004-07-15 Roberto Latini PTX3 as an early prognostic indicator of cardiovascular and cerebrovascular pathologies
JP4667372B2 (ja) * 2004-02-25 2011-04-13 株式会社ペルセウスプロテオミクス 血管障害の程度の判定方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FAZZINI F. ET AL..PTX3 in small-vessel vasculitides an independent indicator of disease activity produced at sites of inflammation.《ARTHRITIS & RHEUMATISM》.2001,第44卷(第12期),第2843页右栏. *
MULLER B. ET AL..Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients.《CRIT. CARE MED.》.2001,第29卷(第7期),第1405页第2栏. *

Also Published As

Publication number Publication date
US20080261251A1 (en) 2008-10-23
JP2007534951A (ja) 2007-11-29
WO2005106494A3 (en) 2006-06-01
CN1947018A (zh) 2007-04-11
ITMI20040858A1 (it) 2004-07-29
JP2011117973A (ja) 2011-06-16
WO2005106494A2 (en) 2005-11-10
EP1740956A2 (en) 2007-01-10
AU2005238637A1 (en) 2005-11-10
KR20070006914A (ko) 2007-01-11
US7915004B2 (en) 2011-03-29
KR101168292B1 (ko) 2012-07-25
CA2562895A1 (en) 2005-11-10
AU2005238637B2 (en) 2010-12-16

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Owner name: LAKEDIO PHARMACEUTICALS DEVELOPMENT AND RESTORABIL

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Granted publication date: 20121219

Termination date: 20140427