JP2011063624A5 - - Google Patents
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- Publication number
- JP2011063624A5 JP2011063624A5 JP2010281284A JP2010281284A JP2011063624A5 JP 2011063624 A5 JP2011063624 A5 JP 2011063624A5 JP 2010281284 A JP2010281284 A JP 2010281284A JP 2010281284 A JP2010281284 A JP 2010281284A JP 2011063624 A5 JP2011063624 A5 JP 2011063624A5
- Authority
- JP
- Japan
- Prior art keywords
- eye drop
- aqueous eye
- transparent
- tranilast
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003889 eye drop Substances 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 3
- NZHGWWWHIYHZNX-CSKARUKUSA-N tranilast Chemical compound C1=C(OC)C(OC)=CC=C1\C=C\C(=O)NC1=CC=CC=C1C(O)=O NZHGWWWHIYHZNX-CSKARUKUSA-N 0.000 claims 3
- 229960005342 tranilast Drugs 0.000 claims 3
- 239000007853 buffer solution Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 238000004806 packaging method and process Methods 0.000 claims 2
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 claims 1
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 claims 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims 1
- 239000004327 boric acid Substances 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 235000019438 castor oil Nutrition 0.000 claims 1
- 229960001777 castor oil Drugs 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 claims 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 1
- 239000002997 ophthalmic solution Substances 0.000 claims 1
- 229940054534 ophthalmic solution Drugs 0.000 claims 1
- 238000001782 photodegradation Methods 0.000 claims 1
- 229920001992 poloxamer 407 Polymers 0.000 claims 1
- 229940044476 poloxamer 407 Drugs 0.000 claims 1
- -1 polyoxyethylene Polymers 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
- 229940068968 polysorbate 80 Drugs 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
- 238000002834 transmittance Methods 0.000 claims 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 1
- 229960000281 trometamol Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010281284A JP5711957B2 (ja) | 2003-09-30 | 2010-12-17 | 透明包装体入りトラニラスト含有医薬製剤 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003342427 | 2003-09-30 | ||
| JP2003342427 | 2003-09-30 | ||
| JP2003382863 | 2003-11-12 | ||
| JP2003382863 | 2003-11-12 | ||
| JP2004028303 | 2004-02-04 | ||
| JP2004028303 | 2004-02-04 | ||
| JP2010281284A JP5711957B2 (ja) | 2003-09-30 | 2010-12-17 | 透明包装体入りトラニラスト含有医薬製剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004098542A Division JP5477996B2 (ja) | 2003-09-30 | 2004-03-30 | 透明包装体入りトラニラスト含有医薬製剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013167436A Division JP2014015467A (ja) | 2003-09-30 | 2013-08-12 | 透明包装体入りトラニラスト含有医薬製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011063624A JP2011063624A (ja) | 2011-03-31 |
| JP2011063624A5 true JP2011063624A5 (enExample) | 2012-01-26 |
| JP5711957B2 JP5711957B2 (ja) | 2015-05-07 |
Family
ID=43950217
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010281284A Expired - Fee Related JP5711957B2 (ja) | 2003-09-30 | 2010-12-17 | 透明包装体入りトラニラスト含有医薬製剤 |
| JP2013167436A Pending JP2014015467A (ja) | 2003-09-30 | 2013-08-12 | 透明包装体入りトラニラスト含有医薬製剤 |
| JP2014202715A Pending JP2015007126A (ja) | 2003-09-30 | 2014-10-01 | 透明包装体入りトラニラスト含有医薬製剤 |
| JP2015227176A Pending JP2016065088A (ja) | 2003-09-30 | 2015-11-20 | 透明包装体入りトラニラスト含有医薬製剤 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013167436A Pending JP2014015467A (ja) | 2003-09-30 | 2013-08-12 | 透明包装体入りトラニラスト含有医薬製剤 |
| JP2014202715A Pending JP2015007126A (ja) | 2003-09-30 | 2014-10-01 | 透明包装体入りトラニラスト含有医薬製剤 |
| JP2015227176A Pending JP2016065088A (ja) | 2003-09-30 | 2015-11-20 | 透明包装体入りトラニラスト含有医薬製剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (4) | JP5711957B2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014024794A (ja) * | 2012-07-27 | 2014-02-06 | Nippon Tenganyaku Kenkyusho:Kk | チモロールまたはその薬学的に許容される塩を含有する水性組成物およびその光安定化方法 |
| CN105283186B (zh) * | 2013-05-30 | 2018-05-18 | 千寿制药株式会社 | 氯苯那敏或其盐的稳定化方法 |
| JP6913792B2 (ja) * | 2015-12-11 | 2021-08-04 | ロート製薬株式会社 | 局所粘膜適用水性組成物 |
| WO2018038102A1 (en) * | 2016-08-23 | 2018-03-01 | Otsuka Pharmaceutical Co., Ltd. | Ophthalmic pharmaceutical composition with improved preservative effectiveness or light stability |
| WO2018142514A1 (ja) * | 2017-02-01 | 2018-08-09 | 協和発酵キリン株式会社 | ダルベポエチンを含む液体医薬組成物 |
| JP2025081880A (ja) * | 2023-11-16 | 2025-05-28 | 科研製薬株式会社 | 液剤容器及び塗布具 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03145421A (ja) * | 1989-10-31 | 1991-06-20 | Zeria Pharmaceut Co Ltd | 安定な点眼剤 |
| JPH07163635A (ja) * | 1993-12-15 | 1995-06-27 | Terumo Corp | 医薬液用遮光性軟質容器 |
| JPH0898870A (ja) * | 1994-09-30 | 1996-04-16 | Nissho Corp | 紫外線遮断性医療用容器 |
| JP3879940B2 (ja) * | 1995-07-11 | 2007-02-14 | 旭化成ファーマ株式会社 | 塩酸ファスジル注射剤 |
| JPH10295777A (ja) * | 1997-04-28 | 1998-11-10 | Taisho Pharmaceut Co Ltd | 安定な抗菌点眼剤 |
| JP4106232B2 (ja) * | 2001-05-09 | 2008-06-25 | ロート製薬株式会社 | 医薬組成物 |
| JP2003231900A (ja) * | 2002-02-12 | 2003-08-19 | Dainippon Jochugiku Co Ltd | 洗浄剤 |
-
2010
- 2010-12-17 JP JP2010281284A patent/JP5711957B2/ja not_active Expired - Fee Related
-
2013
- 2013-08-12 JP JP2013167436A patent/JP2014015467A/ja active Pending
-
2014
- 2014-10-01 JP JP2014202715A patent/JP2015007126A/ja active Pending
-
2015
- 2015-11-20 JP JP2015227176A patent/JP2016065088A/ja active Pending
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