MX342397B - Uso de fluido viscoelastico para producir un producto medicinal para tratar quirurgicamente el ojo. - Google Patents
Uso de fluido viscoelastico para producir un producto medicinal para tratar quirurgicamente el ojo.Info
- Publication number
- MX342397B MX342397B MX2013009984A MX2013009984A MX342397B MX 342397 B MX342397 B MX 342397B MX 2013009984 A MX2013009984 A MX 2013009984A MX 2013009984 A MX2013009984 A MX 2013009984A MX 342397 B MX342397 B MX 342397B
- Authority
- MX
- Mexico
- Prior art keywords
- eye
- producing
- medicinal product
- surgically treating
- viscoelastic fluid
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title abstract 4
- 229940126601 medicinal product Drugs 0.000 title abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 1
- 229920002845 Poly(methacrylic acid) Polymers 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000004372 Polyvinyl alcohol Substances 0.000 abstract 1
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- 229960001631 carbomer Drugs 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 229940105329 carboxymethylcellulose Drugs 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 210000000695 crystalline len Anatomy 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 1
- 229940071826 hydroxyethyl cellulose Drugs 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 229960000502 poloxamer Drugs 0.000 abstract 1
- 229920001983 poloxamer Polymers 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229920002451 polyvinyl alcohol Polymers 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 210000001747 pupil Anatomy 0.000 abstract 1
- 239000000661 sodium alginate Substances 0.000 abstract 1
- 235000010413 sodium alginate Nutrition 0.000 abstract 1
- 229940005550 sodium alginate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
La presente invención se refiere a el uso de un fluido viscoelástico acuoso para producir un producto medicinal para tratar quirúrgicamente el ojo, tal fluido alarga las lentes del cristalino y la pupila del ojo después de ser aplicado a la superficie del ojo desde un recipiente desechable. El fluido viscoelástico contiene un polímero seleccionado del grupo que consiste de hidroxipropilmetilcelulosa, carboximetilcelulosa, hidroxietilcelulosa, ácido hialurónico, alginato de sodio, hidroxipropil guar polivinilpirrolidona, alcohol polivinílico, ácido polimetacrílico (carbómero), copolímero de polioxietileno-polioxipropileno (poloxámero), polietilenglicol, a una concentración de 0.01-30%.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA288/2011A AT511164A1 (de) | 2011-03-03 | 2011-03-03 | Verwendung eines viskoelastischen fluids zur herstellung eines medizinproduktes für die chirurgische behandlung des auges |
| PCT/EP2012/053710 WO2012117115A2 (de) | 2011-03-03 | 2012-03-05 | Verwendung eines viskoelastischen fluids zur herstellung eines medizinproduktes für die chirurgische behandlung des auges |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013009984A MX2013009984A (es) | 2014-02-17 |
| MX342397B true MX342397B (es) | 2016-09-28 |
Family
ID=45808917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013009984A MX342397B (es) | 2011-03-03 | 2012-03-05 | Uso de fluido viscoelastico para producir un producto medicinal para tratar quirurgicamente el ojo. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20130338240A1 (es) |
| EP (1) | EP2680817B1 (es) |
| JP (1) | JP2014506911A (es) |
| KR (1) | KR20140044780A (es) |
| CN (1) | CN103547257B (es) |
| AT (1) | AT511164A1 (es) |
| AU (1) | AU2012222308B2 (es) |
| BR (1) | BR112013022237A2 (es) |
| CA (1) | CA2825485C (es) |
| CL (1) | CL2013002107A1 (es) |
| ES (1) | ES2587510T3 (es) |
| HU (1) | HUE029708T2 (es) |
| IL (1) | IL228093A (es) |
| MX (1) | MX342397B (es) |
| PL (1) | PL2680817T3 (es) |
| RU (1) | RU2603489C2 (es) |
| WO (1) | WO2012117115A2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016203381A1 (en) * | 2015-06-17 | 2016-12-22 | Al.Chi.Mi.A. S.R.L. | Viscoelastic preparation for use in surgical methods of ohphtalmic surgery |
| ITUB20154802A1 (it) * | 2015-10-20 | 2017-04-20 | Medivis S R L | Composizione oftalmica |
| CN105816477A (zh) * | 2016-02-29 | 2016-08-03 | 李志伟 | 一种角膜表面保护剂在全麻手术中的应用 |
| CN105749360B (zh) * | 2016-03-28 | 2019-06-18 | 赛克赛斯生物科技股份有限公司 | 一种保护角膜的组合物及其制备方法与应用 |
| CN107812243A (zh) * | 2017-09-21 | 2018-03-20 | 李春晖 | 一种角膜保护粘弹液 |
| CA3080016A1 (en) * | 2017-11-22 | 2019-05-31 | Bausch & Lomb Incorporated | Ophthalmic viscoelastic compositions |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4819617A (en) * | 1986-09-04 | 1989-04-11 | University Of Florida | Viscoelastic material for ophthalmic surgery |
| US4965253A (en) * | 1987-10-14 | 1990-10-23 | University Of Florida | Viscoelastic material for ophthalmic surgery |
| US6271216B1 (en) * | 1989-07-24 | 2001-08-07 | Allergan | Stable solution of hyaluronate in a balanced salt medium |
| EP0414373B2 (en) | 1989-07-24 | 2001-04-25 | Allergan Pharmaceuticals (Ireland) Limited | Stable solution of hyaluronate in a balanced salt medium |
| EP0510270A1 (en) * | 1991-04-25 | 1992-10-28 | LINDSTROM, Richard L. | Viscoelastic solution |
| JPH05310580A (ja) | 1992-04-30 | 1993-11-22 | Shiseido Co Ltd | 眼内灌流用液剤 |
| IT1273011B (it) | 1994-07-25 | 1997-07-01 | Trhecnopharma S A | Preparato oftalmico per l'uso come lacrima artificiale |
| US6277365B1 (en) | 1997-09-18 | 2001-08-21 | Bausch & Lomb Incorporated | Ophthalmic composition including a cationic glycoside and an anionic therapeutic agent |
| DE19853007C2 (de) * | 1998-11-17 | 2000-11-30 | Matthias Meyer | Hyaluronsäure enthaltende Irrigationslösung für Operationen am Auge |
| JP2002193815A (ja) * | 2000-12-25 | 2002-07-10 | Ophtecs Corp | 眼手術用角膜乾燥防止点眼剤 |
| WO2003000231A1 (en) * | 2001-06-22 | 2003-01-03 | Alcon, Inc. | Hydration compositions for corneal pre-surgery treatment |
| US20040137079A1 (en) | 2003-01-08 | 2004-07-15 | Cook James N. | Contact lens and eye drop rewetter compositions and methods |
| CN1524579B (zh) * | 2003-02-27 | 2010-04-28 | 李俊 | 复合粘弹剂 |
| US20060073184A1 (en) * | 2004-09-29 | 2006-04-06 | Bausch & Lomb Inc. | Viscoelastic composition, methods of use and packaging device with anti-oxidant |
| ITMI20052036A1 (it) | 2005-10-26 | 2007-04-27 | Professional Dietetics Srl | Composizioni farmaceutiche oftalmiche a base di amminoacidi e sodio ialuronato |
| DE102005055275A1 (de) | 2005-11-17 | 2007-05-24 | Ursapharm Arzneimittel Gmbh & Co. Kg | Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung |
| RU2600863C2 (ru) * | 2007-12-10 | 2016-10-27 | Сентисс Фарма Прайвит Лимитед | Офтальмическая композиция, включающая фенилэфрин |
| CN101676319A (zh) * | 2008-09-19 | 2010-03-24 | 上海建华精细生物制品有限公司 | 注射级医用透明质酸钠凝胶 |
| ITRM20090102U1 (it) | 2009-06-15 | 2010-12-16 | Alfa Intes Ind Terapeutica Splendore S R L | Ialuvit preparato per la stabilizzazione del film lacrimale, la cicatrizzazione corneale e il ripristino del contenuto salino della lacrima e osmoprotezione. |
-
2011
- 2011-03-03 AT ATA288/2011A patent/AT511164A1/de not_active Application Discontinuation
-
2012
- 2012-03-05 JP JP2013555897A patent/JP2014506911A/ja active Pending
- 2012-03-05 BR BR112013022237A patent/BR112013022237A2/pt not_active Application Discontinuation
- 2012-03-05 EP EP12707101.7A patent/EP2680817B1/de not_active Revoked
- 2012-03-05 PL PL12707101.7T patent/PL2680817T3/pl unknown
- 2012-03-05 RU RU2013141546/15A patent/RU2603489C2/ru active
- 2012-03-05 ES ES12707101.7T patent/ES2587510T3/es active Active
- 2012-03-05 CN CN201280011250.4A patent/CN103547257B/zh active Active
- 2012-03-05 HU HUE12707101A patent/HUE029708T2/en unknown
- 2012-03-05 WO PCT/EP2012/053710 patent/WO2012117115A2/de not_active Ceased
- 2012-03-05 MX MX2013009984A patent/MX342397B/es active IP Right Grant
- 2012-03-05 US US14/002,438 patent/US20130338240A1/en not_active Abandoned
- 2012-03-05 AU AU2012222308A patent/AU2012222308B2/en active Active
- 2012-03-05 CA CA2825485A patent/CA2825485C/en active Active
- 2012-03-05 KR KR1020137023158A patent/KR20140044780A/ko not_active Ceased
-
2013
- 2013-07-23 CL CL2013002107A patent/CL2013002107A1/es unknown
- 2013-08-22 IL IL228093A patent/IL228093A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| IL228093A (en) | 2016-07-31 |
| CL2013002107A1 (es) | 2014-05-09 |
| WO2012117115A2 (de) | 2012-09-07 |
| MX2013009984A (es) | 2014-02-17 |
| JP2014506911A (ja) | 2014-03-20 |
| ES2587510T3 (es) | 2016-10-25 |
| CA2825485C (en) | 2017-07-18 |
| PL2680817T3 (pl) | 2016-12-30 |
| IL228093A0 (en) | 2013-09-30 |
| CN103547257B (zh) | 2016-05-18 |
| RU2603489C2 (ru) | 2016-11-27 |
| US20130338240A1 (en) | 2013-12-19 |
| CA2825485A1 (en) | 2012-09-07 |
| BR112013022237A2 (pt) | 2016-12-06 |
| WO2012117115A3 (de) | 2013-01-10 |
| RU2013141546A (ru) | 2015-04-10 |
| CN103547257A (zh) | 2014-01-29 |
| AU2012222308B2 (en) | 2017-04-06 |
| EP2680817B1 (de) | 2016-05-25 |
| EP2680817A2 (de) | 2014-01-08 |
| HUE029708T2 (en) | 2017-03-28 |
| AU2012222308A1 (en) | 2013-08-22 |
| KR20140044780A (ko) | 2014-04-15 |
| AT511164A1 (de) | 2012-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX342397B (es) | Uso de fluido viscoelastico para producir un producto medicinal para tratar quirurgicamente el ojo. | |
| Schanté et al. | Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications | |
| CL2017000830A1 (es) | Formulación estable que comprende un azúcar no reductora, un anticuerpo anti-s4b7 y al menos un aminoácido libre; un método para preparar dicha formulación; uso de dicha formulación para tratar una enfermedad inflamatoria del intestino. | |
| UA114351C2 (uk) | Поліциклічні карбамоїлпіридонові сполуки та їх фармацевтичне застосування | |
| HK1224315A1 (zh) | 用於制备交联的透明质酸产物的方法 | |
| FI3811943T3 (fi) | Yhdiste käytettäväksi silmäsairauksien hoidossa | |
| MX2017007814A (es) | Compuesto de carbamoilpiridona policiclicos y su uso farmaceutico. | |
| MX378984B (es) | Nanoparticulas terapeuticas que comprenden un agente terapeutico, y metodos para su elaboracion y uso. | |
| IL232267A (en) | Derivatives of (4-phenylimidazole-2-ram) ethylamine, pharmaceuticals containing them used to treat them in diseases where sodium channel inhibition nav 1.8 is effective | |
| WO2010088000A3 (en) | Antifibrotic compounds and uses thereof | |
| NZ628398A (en) | Stable preservative-free mydriatic and anti-inflammatory solutions for injection | |
| RU2014146519A (ru) | Хондроитин для применения в медицине | |
| JP2013535477A5 (es) | ||
| WO2014143754A3 (en) | Prostamide-containing intraocular implant | |
| AR085616A1 (es) | Composicion farmaceutica inhalable que comprende glicopirrolato, uso | |
| JP2015147762A5 (es) | ||
| CL2013003730A1 (es) | Polimero de vinil alcohol de formula p-(r)n, donde p es la cadena principal, que comprende uno o mas grupos de acoplamiento reactivos, y donde r es un aminosilano y/o una cadena lateral que contiene aminosilanol unido a la cadena principal; procedimiento para preparar dicho polimero; proceso para preparar un recubrimiento; composicion; uso del copolimero; tinta; y recubrimiento. | |
| WO2015097600A3 (en) | Topical brimonidine tartrate ophthalmic solution | |
| ES2613698T3 (es) | Combinación, kit y método de reducción de la presión intraocular | |
| WO2014165513A3 (en) | Ethylsulfonated hyaluronic acid biopolymers and methods of use thereof | |
| SI2555770T1 (en) | Ketorolac compositions for corneal wound healing | |
| BR112012014320A2 (pt) | novos solvatos de metil{4,6-diamino-2-[1-(2-fluorobenzil)-1h-pirazolo [3,4-b]piridin-3-il)pirimidin-5-il}carbamato | |
| CN204049998U (zh) | 一种眼科滴眼液缓释瓶 | |
| WO2013171766A3 (en) | Saxagliptin solid dispersion | |
| GB201114317D0 (en) | Ophthalmologic composition comprising an aqueous solution of at least one viscoelastic polysaccharide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: VALEANT SP. Z O.O. SP. J. |
|
| FG | Grant or registration |