|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US5869620A
(en)
*
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
US5260203A
(en)
*
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US5869053A
(en)
*
|
1988-03-04 |
1999-02-09 |
Cancer Research Campaign Technology, Ltd. |
5T4 antigen from human trophoblasts
|
|
US4892824A
(en)
*
|
1988-03-15 |
1990-01-09 |
Synbiotics Corporation |
Fast track method for producing monoclonal bi-specific immunoglobulins
|
|
US6010902A
(en)
*
|
1988-04-04 |
2000-01-04 |
Bristol-Meyers Squibb Company |
Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
|
|
US5162504A
(en)
|
1988-06-03 |
1992-11-10 |
Cytogen Corporation |
Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
DE3920358A1
(de)
*
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
WO1991000906A1
(en)
|
1989-07-12 |
1991-01-24 |
Genetics Institute, Inc. |
Chimeric and transgenic animals capable of producing human antibodies
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
EP1690934A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
ATE352612T1
(de)
|
1990-08-29 |
2007-02-15 |
Pharming Intellectual Pty Bv |
Homologe rekombination in säugetier-zellen
|
|
ATE300615T1
(de)
|
1990-08-29 |
2005-08-15 |
Genpharm Int |
Transgene mäuse fähig zur produktion heterologer antikörper
|
|
US6197298B1
(en)
*
|
1991-04-19 |
2001-03-06 |
Tanox, Inc. |
Modified binding molecules specific for T lymphocytes and their use as in vivo immune modulators in animals
|
|
DE4140142A1
(de)
*
|
1991-12-05 |
1993-06-09 |
Boehringer Mannheim Gmbh, 6800 Mannheim, De |
Multivalentes dextranreagenz zum einsatz in praezipitationstests
|
|
US5965132A
(en)
*
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
ES2149768T3
(es)
|
1992-03-25 |
2000-11-16 |
Immunogen Inc |
Conjugados de agentes enlazantes de celulas derivados de cc-1065.
|
|
US6096289A
(en)
*
|
1992-05-06 |
2000-08-01 |
Immunomedics, Inc. |
Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy
|
|
WO1994013806A1
(en)
*
|
1992-12-11 |
1994-06-23 |
The Dow Chemical Company |
Multivalent single chain antibodies
|
|
US5861156A
(en)
*
|
1993-01-08 |
1999-01-19 |
Creative Biomolecules |
Methods of delivering agents to target cells
|
|
US5705614A
(en)
*
|
1993-04-09 |
1998-01-06 |
Chiron Corporation |
Methods of producing antigen forks
|
|
US5869049A
(en)
*
|
1993-09-02 |
1999-02-09 |
Trustees Of Dartmouth College |
Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists
|
|
US6569432B1
(en)
*
|
1995-02-24 |
2003-05-27 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen and uses thereof
|
|
GB9324807D0
(en)
*
|
1993-12-03 |
1994-01-19 |
Cancer Res Campaign Tech |
Tumour antibody
|
|
US5559099A
(en)
*
|
1994-09-08 |
1996-09-24 |
Genvec, Inc. |
Penton base protein and methods of using same
|
|
ATE317435T1
(de)
*
|
1995-02-24 |
2006-02-15 |
Sloan Kettering Inst Cancer |
Prostataspezifisches membranes antigen und seine anwendungen
|
|
GB9504344D0
(en)
*
|
1995-03-03 |
1995-04-19 |
Unilever Plc |
Antibody fragment production
|
|
US5747035A
(en)
*
|
1995-04-14 |
1998-05-05 |
Genentech, Inc. |
Polypeptides with increased half-life for use in treating disorders involving the LFA-1 receptor
|
|
US6150508A
(en)
|
1996-03-25 |
2000-11-21 |
Northwest Biotherapeutics, Inc. |
Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
|
|
US6136311A
(en)
*
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
US6107090A
(en)
|
1996-05-06 |
2000-08-22 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
|
|
GB9712818D0
(en)
*
|
1996-07-08 |
1997-08-20 |
Cambridge Antibody Tech |
Labelling and selection of specific binding molecules
|
|
US5922845A
(en)
*
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
|
WO1998045419A1
(en)
*
|
1997-04-03 |
1998-10-15 |
Universite Laval |
Transgenic expression in genital tract and sexual accessory glands
|
|
WO1998052976A1
(en)
|
1997-05-21 |
1998-11-26 |
Biovation Limited |
Method for the production of non-immunogenic proteins
|
|
AU8296098A
(en)
*
|
1997-07-08 |
1999-02-08 |
Board Of Regents, The University Of Texas System |
Compositions and methods for homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
|
US6977074B2
(en)
*
|
1997-07-10 |
2005-12-20 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
US6994851B1
(en)
*
|
1997-07-10 |
2006-02-07 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
US6030792A
(en)
*
|
1997-11-13 |
2000-02-29 |
Pfizer Inc |
Assays for measurement of protein fragments in biological media
|
|
US5981209A
(en)
|
1997-12-04 |
1999-11-09 |
Guilford Pharmaceuticals Inc. |
Use of NAALADase activity to identify prostate cancer and benign prostatic hyperplasia
|
|
US6709844B1
(en)
*
|
2000-11-16 |
2004-03-23 |
Mannkind Corporation |
Avoidance of undesirable replication intermediates in plasmid propagation
|
|
ES2434961T5
(es)
*
|
1998-04-20 |
2018-01-18 |
Roche Glycart Ag |
Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo
|
|
US6200765B1
(en)
*
|
1998-05-04 |
2001-03-13 |
Pacific Northwest Cancer Foundation |
Non-invasive methods to detect prostate cancer
|
|
AU757698C
(en)
*
|
1998-06-01 |
2004-04-08 |
Agensys, Inc. |
Novel serpentine transmembrane antigens expressed in human cancers and uses thereof
|
|
US6833438B1
(en)
*
|
1999-06-01 |
2004-12-21 |
Agensys, Inc. |
Serpentine transmembrane antigens expressed in human cancers and uses thereof
|
|
US20030149531A1
(en)
*
|
2000-12-06 |
2003-08-07 |
Hubert Rene S. |
Serpentine transmembrane antigens expressed in human cancers and uses thereof
|
|
US6361774B1
(en)
*
|
1999-09-17 |
2002-03-26 |
Immunomedics, Inc. |
Methods and compositions for increasing the target-specific toxicity of a chemotherapy drug
|
|
WO2000034317A2
(en)
|
1998-12-08 |
2000-06-15 |
Biovation Limited |
Method for reducing immunogenicity of proteins
|
|
ATE399796T1
(de)
*
|
1999-04-09 |
2008-07-15 |
Univ Zuerich |
Verfahren zur stabilisierung von chimären immunoglobulinen oder immunoglobulinfragmenten und stabilisiertes anti-egp-2-scfv-fragment
|
|
EP1179541B1
(en)
*
|
1999-04-28 |
2004-06-16 |
Board Of Regents, The University Of Texas System |
Compositions and methods for cancer treatment by selectively inhibiting VEGF
|
|
US6342587B1
(en)
*
|
1999-10-22 |
2002-01-29 |
Ludwig Institute For Cancer Research |
A33 antigen specific immunoglobulin products and uses thereof
|
|
ES2276708T3
(es)
*
|
1999-11-24 |
2007-07-01 |
Immunogen, Inc. |
Agentes citotoxicos que comprenden taxanos y su uso terapeutico.
|
|
CN1423700A
(zh)
*
|
2000-03-24 |
2003-06-11 |
麦克美特股份公司 |
含有针对nkg2d受体复合物的表位的结合位点的多功能多肽
|
|
CN101289511A
(zh)
*
|
2000-04-11 |
2008-10-22 |
杰南技术公司 |
多价抗体及其应用
|
|
US6861234B1
(en)
*
|
2000-04-28 |
2005-03-01 |
Mannkind Corporation |
Method of epitope discovery
|
|
US6375991B1
(en)
*
|
2000-09-08 |
2002-04-23 |
Albemarle Corporation |
Production of concentrated biocidal solutions
|
|
DE10045591A1
(de)
*
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
|
WO2002092553A1
(en)
|
2001-05-11 |
2002-11-21 |
Guilford Pharmaceuticals Inc. |
Hydroxamic acids and acyl hydroxamines as naaladase inhibitors
|
|
US20090226429A1
(en)
*
|
2001-05-25 |
2009-09-10 |
Human Genome Sciences, Inc. |
Antibodies That Immunospecifically Bind to TRAIL Receptors
|
|
US7514078B2
(en)
*
|
2001-06-01 |
2009-04-07 |
Cornell Research Foundation, Inc. |
Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies
|
|
US7666414B2
(en)
|
2001-06-01 |
2010-02-23 |
Cornell Research Foundation, Inc. |
Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen
|
|
EP2277542B1
(en)
*
|
2001-06-01 |
2014-04-16 |
Cornell Research Foundation Inc. |
Modified antibodies to prostrate-specific membrane antigen and uses thereof
|
|
US7494646B2
(en)
*
|
2001-09-06 |
2009-02-24 |
Agensys, Inc. |
Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
|
|
ES2537074T3
(es)
*
|
2001-09-06 |
2015-06-02 |
Agensys, Inc. |
Ácido nucleico y proteína correspondiente denominados STEAP-1 útiles en el tratamiento y la detección de cáncer
|
|
IL159422A0
(en)
*
|
2001-09-20 |
2004-06-01 |
Cornell Res Foundation Inc |
Methods and compositions for treating or preventing skin disorders using binding agents specific for prostate-specific membrane antigen
|
|
WO2003034903A2
(en)
*
|
2001-10-23 |
2003-05-01 |
Psma Development Company, L.L.C. |
Psma antibodies and protein multimers
|
|
HUP0600342A3
(en)
*
|
2001-10-25 |
2011-03-28 |
Genentech Inc |
Glycoprotein compositions
|
|
US20040018519A1
(en)
*
|
2001-11-16 |
2004-01-29 |
Wright ,Jr. George L |
Methods and devices for quantitative detection of prostate specific membrane antigen and other prostatic markers
|
|
AU2003210802B2
(en)
*
|
2002-02-05 |
2009-09-10 |
Genentech Inc. |
Protein purification
|
|
CA2478925C
(en)
*
|
2002-04-26 |
2016-06-07 |
Robert Lee Fahrner |
Non-affinity purification of proteins
|
|
JP2004000045A
(ja)
*
|
2002-05-31 |
2004-01-08 |
Kyowa Hakko Kogyo Co Ltd |
前立腺特異的膜抗原に対する抗体
|
|
WO2004001004A2
(en)
*
|
2002-06-21 |
2003-12-31 |
Johns Hopkins University School Of Medicine |
Membrane associated tumor endothelium markers
|
|
WO2004088279A2
(en)
*
|
2003-03-28 |
2004-10-14 |
Iowa State University Research Foundation, Inc. |
Allosteric probes and methods
|
|
CA2529945A1
(en)
*
|
2003-06-27 |
2005-01-06 |
Biogen Idec Ma Inc. |
Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions
|
|
EP1648940B1
(en)
*
|
2003-07-28 |
2016-04-27 |
Genentech, Inc. |
Reducing protein a leaching during protein a affinity chromatography
|
|
US7524813B2
(en)
*
|
2003-10-10 |
2009-04-28 |
Novo Nordisk Health Care Ag |
Selectively conjugated peptides and methods of making the same
|
|
DE602004030811D1
(de)
*
|
2003-10-16 |
2011-02-10 |
Micromet Ag |
Multispezifische deimmunisierte cd3-bindende moleküle
|
|
US7498298B2
(en)
*
|
2003-11-06 |
2009-03-03 |
Seattle Genetics, Inc. |
Monomethylvaline compounds capable of conjugation to ligands
|
|
EP1704228B1
(en)
*
|
2004-01-16 |
2012-04-11 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Immunokinases
|
|
EP1718667B1
(en)
*
|
2004-02-23 |
2013-01-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
EP1610818A4
(en)
*
|
2004-03-03 |
2007-09-19 |
Millennium Pharm Inc |
MODIFIED ANTIBODIES AGAINST A PROSTATE-SPECIFIC MEMBRANE-ANTIGEN AND USE THEREOF
|
|
WO2005101017A1
(en)
*
|
2004-04-07 |
2005-10-27 |
Genentech, Inc. |
Mass spectrometry of antibody conjugates
|
|
ES2443996T3
(es)
*
|
2004-04-22 |
2014-02-21 |
Agensys, Inc. |
Anticuerpos y moléculas derivadas de los mismos que se unen a proteínas STEAP-1
|
|
AU2005263555B2
(en)
*
|
2004-07-16 |
2011-01-27 |
Amgen Research (Munich) Gmbh |
Expression-enhanced polypeptides
|
|
KR101270829B1
(ko)
*
|
2004-09-23 |
2013-06-07 |
제넨테크, 인크. |
시스테인 유전자조작 항체 및 접합체
|
|
US20100111856A1
(en)
*
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
BRPI0607796A2
(pt)
*
|
2005-02-18 |
2009-06-13 |
Medarex Inc |
composto ou um sal farmaceuticamente aceitável do mesmo, processo para preparação e uso do mesmo, e, composição farmacêutica
|
|
HRP20140338T1
(hr)
*
|
2005-07-25 |
2014-06-20 |
Emergent Product Development Seattle, Llc |
Smanjenje broja b-stanica upotrebom molekula koje se specifiäśno vežu na cd37 i cd20
|
|
US7612181B2
(en)
*
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
EP2144930A1
(en)
*
|
2007-04-18 |
2010-01-20 |
ZymoGenetics, Inc. |
Single chain fc, methods of making and methods of treatment
|
|
NZ601827A
(en)
*
|
2007-10-18 |
2014-01-31 |
Bavarian Nordic Inc |
Use of mva to treat prostate cancer
|
|
US8742076B2
(en)
*
|
2008-02-01 |
2014-06-03 |
Genentech, Inc. |
Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
|
|
CN102159248B
(zh)
*
|
2008-07-15 |
2013-09-11 |
健泰科生物技术公司 |
蒽环类衍生物缀合物、它们的制备方法以及它们作为抗肿瘤化合物的用途
|
|
US20100069616A1
(en)
*
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
|
AU2009288561B2
(en)
*
|
2008-09-08 |
2014-07-24 |
Conocophillips Company |
System for incondensable component separation in a liquefied natural gas facility
|
|
EP2358912B1
(en)
*
|
2008-10-30 |
2016-10-12 |
Caris Life Sciences Switzerland Holdings GmbH |
Methods for assessing rna patterns
|
|
GB2463401B
(en)
*
|
2008-11-12 |
2014-01-29 |
Caris Life Sciences Luxembourg Holdings S A R L |
Characterizing prostate disorders by analysis of microvesicles
|
|
US20110020327A1
(en)
*
|
2008-12-16 |
2011-01-27 |
Millipore Corporation |
Purification of proteins
|
|
US8424854B2
(en)
*
|
2008-12-25 |
2013-04-23 |
Tokai Rubber Industries, Ltd. |
Fluid-filled type vibration damping device
|
|
JP2012525149A
(ja)
*
|
2009-04-27 |
2012-10-22 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
ヘテロ多量体分子を作製するための方法
|
|
US8416206B2
(en)
*
|
2009-07-08 |
2013-04-09 |
Smart Technologies Ulc |
Method for manipulating a graphic widget in a three-dimensional environment displayed on a touch panel of an interactive input system
|
|
TWM383852U
(en)
*
|
2009-07-13 |
2010-07-01 |
Speedtech Corp |
An improvement of the universal serial bus connector
|
|
JPWO2011043061A1
(ja)
*
|
2009-10-05 |
2013-03-04 |
キヤノン株式会社 |
光音響イメージング用造影剤、及び、それを用いた光音響イメージング方法
|